Robotic Capsule Drills Intestinal Mucus to Deliver Protein Drugs
Engineers at MIT have collaborated to develop a robotic drug delivery capsule that is specially designed to administer delicate protein drugs, such as insulin, through the wall of the intestine. Proteins are not suited for oral delivery, as they are typically destroyed by the low pH in the intestine and they can’t pass through the mucus layer that lines the gastrointestinal tract.
Protecting protein drugs from the acidic environment and providing a way to traverse this mucus layer is the goal behind this latest technology. The capsule can be loaded with the protein and then once swallowed it becomes activated by ...
Source: Medgadget - October 5, 2022 Category: Medical Devices Authors: Conn Hastings Tags: GI Materials Medicine mit MITnews Source Type: blogs
How to know if chest pain is due to heart disease or not? Cardiology Basics
It is not always possible to be certain about the origin of chest pain just by its characteristics as the variation between individuals is quite a bit. There can be a lot of overlap between symptoms due to heart disease and disease of other nearby organs.
Still some general observations are possible regarding chest pain originating from the heart. The typical pain of cardiac origin is a central chest pain which occurs on walking or other forms of exercise, known as effort angina. This pain is caused by insufficient blood supply to a region of the myocardium. Effort angina is commonly due to significant obstruction to a co...
Source: Cardiophile MD - October 4, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Soft Robot Grows Like a Plant to Travel Through Tight Spaces
At the University of Minnesota, researchers have developed a soft robotic system that can ‘grow’ like a plant. The mechanism allows it to travel through difficult-to-access areas, such as the tortuous gastrointestinal tract or vasculature. The system works by extruding a liquid through an opening in the device, and at the same time a photopolymerization process results in the rapid solidification of the liquid into a solid structure. The device illuminates the extruded liquid monomers, triggering the photopolymerization. This process mimics the way plants incrementally add material to their growing tips and root tips. ...
Source: Medgadget - October 3, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery GI Materials Radiology Telemedicine Vascular Surgery UMNews Source Type: blogs
Targeting the Gut Microbiome to Treat Aging
The distribution of microbial populations making up the gut microbiome changes with age in ways that are harmful to health, causing a reduction in production of beneficial metabolites and an increase in chronic inflammation. Animal studies make it clear that some approaches to restoring a more youthful gut microbiome, such as fecal microbiota transplantation from young donors, can produce a sustained rejuvenation of the gut microbiome and consequent improvement in later life health. Given the comparatively simplicity of this approach, and that the state of the gut microbiome can accurately measured via low-cost assays, thi...
Source: Fight Aging! - October 3, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Contrasting results of REDUCE-IT and STRENGTH trials of Omega 3
Contrasting results of REDUCE-IT [1] and STRENGTH [2] trials of Omega 3 fatty acid preparations have caught the attention of scientific community. Icosapent ethyl, a highly purified eicosapentaenoic acid ethyl ester was evaluated in REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial). In STRENGTH trial carboxylic acid formulation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were used.
REDUCE-IT was a multicenter, randomized, double blind, placebo controlled trial. Patients enrolled had established cardiovascular disease or diabetes with other risk factors. They were rece...
Source: Cardiophile MD - September 27, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Weekly Overseas Health IT Links –24th September, 2022.
This article makes the case and explains what will be required to make it happen.We hear a lot about “digital health” these days. As data about our health piles up — thanks to sources like electronic health records, personal fitness apps and gadgets, and home genome test kits — weshould understand a lot more than we used to about what ’s wrong with our health and what to do about it. But having a lot of data is not enough. We have to be aware of what we have, understand what it means, and act on that understanding. While the challenges are in some ways more acute in the United States because of its fragmented sys...
Source: Australian Health Information Technology - September 24, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
I ’ m a doctor who just had his first colonoscopy in my 60s — without anesthesia
Well, I am that family physician and geriatrician who is now almost 70 years old. And I cannot believe it because, in some ways, I am still like 27 years old! First of all, I’m very healthy, and I’m lucky that nobody in my family had colon cancer or any cancer. Most of my relatives
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I’m a doctor who just had his first colonoscopy in my 60s — without anesthesia originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 23, 2022 Category: General Medicine Authors: Mike Neskovic, MD Tags: Conditions Gastroenterology Source Type: blogs
Myalgic encephalomyelitis/chronic fatigue syndrome and long COVID [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “ME/CFS is a complex multi-system illness that destroys lives (essentially killing the person yet leaving them alive). It leaves patients with unimaginable fatigue, post-exertional malaise (meaning that minor exertion makes them feel worse), cognitive deficits, cardiovascular dysfunction, gastrointestinal malfunctions, unrefreshing sleep, pain, and much
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Myalgic encephalomyelitis/chronic fatigue syndrome and long COVID [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 20, 2022 Category: General Medicine Authors: The Podcast by KevinMD Tags: Podcast COVID Rheumatology Source Type: blogs
Soft Robot Biodegrades Inside Body
Researchers at the City University of Hong Kong have developed a magnetic soft millirobot that can grab and release objects, and move around by rolling. The device can be controlled using magnetic fields, and consists of a biodegradable gelatin and iron oxide microparticles.
The technology has significant potential as a minimally invasive drug delivery system, perhaps in the gastrointestinal tract, and may even lead to soft robots that can carry out surgical procedures within the body. One of the nicest features of the device is its rapid biodegradation over the space of a couple of days, which means that it may not ha...
Source: Medgadget - September 19, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Surgery CityUHongKong microrobotics microrobots millirobot Source Type: blogs
Bonus Features – September 18, 2022 – HIMSS and WHO to collaborate on digital health, inpatient admissions for pediatric mental health up 60% since 2016, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News and Studies
WHO/Europe and HIMSS have signed an agreement to collaborate on digital health, with the entities saying the partnership will allow for a more aligned approach to digital transformation in Europe. Under the agre...
Source: EMR and HIPAA - September 18, 2022 Category: Information Technology Authors: Brian Eastwood Tags: Health IT Company Healthcare IT Amanda Bury American Telemedicine Association Arcadia ATA BridgeHead Software BrithInsihgt CereCore Clarify Health Dartmouth Health Dash Chat Edifecs ePrescribing First Health Advisory Forescou Source Type: blogs
Why are women leaving medicine? Gaslighting. [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “We cannot change societal norms, gender biases, childhood needs, the education system, or stop a pandemic. But, we can stop gaslighting 50% of the population. We can start acknowledging that the simple fact of gender does greatly affect patient and support staff expectations, time,
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Why are women leaving medicine? Gaslighting. [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 15, 2022 Category: General Medicine Authors: The Podcast by KevinMD Tags: Podcast Gastroenterology Source Type: blogs
I Suspect It Says Something That A Three Million Dollar Grant In Digital Health Makes News!
This release appeared last week.ANDHealth - Special Announcement: 7 September 2022ANDHealth, Australia ’s leading digital health commercialisation organisation, in partnership with the Victorian Government, today announced it has received $2.4M from the Australian Medtech Manufacturing Centre and Biotechnology Fund to create the Victorian Connected Health Innovation& Commercialisation Centre (CHICC).The CHICC has been established to drive the creation and commercialisation of digital and digitally enabled medical technology companies and raise Victoria ’s profile as a leading centre for Australia’s fast grow...
Source: Australian Health Information Technology - September 14, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Weekly Australian Health IT Links – 12 September, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----It is amazing how many senior roles at the ADHA are being advertised it seem. Some at $150,000 plus!To keep busy we have vapourware interop plans being discussed and bullshit educational sessions being run for lesser salaries!Otherwise it has been a pretty boring week I have to say!-----https://www.ama.com.au/gpnn/issue-22-number-...
Source: Australian Health Information Technology - September 12, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, September 12th 2022
Discussion of Present Drug Development to Target Senescent Cells
Targeting Senescent Cells to Better Address Cancer and Consequences of Cancer Therapy
Calorie Restriction Suppresses Generation of Immune Cells via Changes to the Gut Microbiome
Arguing for an Expansion of the Hallmarks of Aging
https://www.fightaging.org/archives/2022/09/arguing-for-an-expansion-of-the-hallmarks-of-aging/
The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. Thi...
Source: Fight Aging! - September 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Using the Peripheral Nervous System as a Source of Cells for Central Nervous System Regeneration
It is in principle possible to obtain cells from the peripheral nervous system that may, once cultured and expanded in number, and possibly altered in their behavior via the application of suitable signal molecules, produce regeneration in the brain or other portions of the central nervous system. The peripheral nervous system is more readily accessed than the central nervous system, and this is the big point in favor of searching the periphery of the body for cells that might be useful in areas of the more protected, less accessible inner body.
With a steadily aging population there is an increasing prevalence of...
Source: Fight Aging! - September 6, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
