What does LBBB look like in severe hypothermia? Is there a long QT? Is the QT appropriate for the temperature?
This patient was found down in a Minneapolis winter. He was very cold with frostbitten fingers and toes. He was alert but encephalopathic and delirious and very agitated and could not be adequately calmed with olanzapine and lorazepam, so we intubated him. The first reliable temperature could only be obtained with a Foley thermistor, and it was 26.5 degrees C (79.7 F).His BP was 76/60. K was 2.8 mEq/L.Here was his first ECG:There is sinus bradycardia with left bundle branch block (LBBB), with proportional ST-T, and VERY long QT and a PVC. I measure the QT at 800 ms. Notice that there are ...
Source: Dr. Smith's ECG Blog - January 6, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs
Answer to Case 667
Answer to theParasite Case of the Week 667: Ascaris lumbricoides. This adult nematode is easy to identify when found in human stool, or expelled through the mouth, nose, or anus, due to its large size and characteristic 3 fleshy lips. Importantly, anisakid larvae also have 3 fleshy lips, and must therefore be differentiated from immatureAscariswhen expelled from the human gastrointestinal tract. This can be accomplished by examining the characteristics of the intestinal tract, mouth and tail.Thanks again to Heather for this beautiful photograph! (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - January 2, 2022 Category: Parasitology Source Type: blogs
Thought-to-Text Brain-Computer Interface: Interview with Florian Solzbacher, Chairman of Blackrock Neurotech
Blackrock Neurotech, a medical technology company based in Salt Lake City, created a suite of brain-computer interface systems with the goal of empowering patients to have increased independence and quality of life. This latest technology aims to restore written communication in patients who have difficulties in this regard, such as those affected by paralysis.
The company’s new system, which Blackrock aims to make available in late 2022, allows patients to type text by merely imagining themselves writing or typing the words. The system uses machine learning to decode neural signals that occur while someone is ima...
Source: Medgadget - December 28, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurology Neurosurgery Rehab Source Type: blogs
Fight Aging! Newsletter, December 27th 2021
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - December 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A reflection on stomach surgery
One of the most dramatic changes from my training to the present is the nearly complete disappearance of elective ulcer surgery. (Reminder: as I’ve said before,“elective” means non-emergent, as opposed to unnecessary.) The revolution began with the advent of drugs that effectively reduce gastric acid production and settled in for real when the relationshipRead more …A reflection on stomach surgery originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 25, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/sid-schwab" rel="tag" > Sid Schwab, MD < /a > < /span > Tags: Physician Surgery Source Type: blogs
Nicotinamide Mononucleotide Supplement Adjusts the Gut Microbiome
In today's open access paper, the authors report on their investigation of the effects of nicotinamide mononucleotide (NMN) supplementation on the gut microbiome in mice. The gut microbiome changes with age, exhibiting a loss of helpful populations that produce metabolites necessary to health, and the growth in harmful populations that provoke chronic inflammation. Rejuvenating the aged gut microbiome via fecal microbiota transplantation from a young individual has been shown to improve health and extend life in short-lived species. Thus there is some interest in evaluating the effects on the gut microbiome produced by int...
Source: Fight Aging! - December 24, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
“Playing Doctor” – A Cautionary Tale From Health IT Pioneers.
By MIKE MAGEE
Warner Vincent Slack, MD, a pioneer of medical informatics, was a Professor of Medicine at Harvard Medical School in the Division of Clinical Informatics. When he died in 2018 at age 85, his memoriam read:
“For over 50 years, Dr. Slack conducted pioneering research on the use of computers in the medical world and was one of the founders of medical informatics. His goal was to empower both doctors and patients by improving the communication between them.”
Followers of Dr. Slack have labored hard over the past half-century to design solutions that will strengthen rather than weaken the bonds of the...
Source: The Health Care Blog - December 17, 2021 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Politics Dr. Slack Health Information Technology Mike Magee Supreme Court terry schiavo Warner Vincent Slack Source Type: blogs
Innovation in a rural gastroenterology practice using a farm
The cost of health care in the United States continues to rise, totaling over $3.8 trillion per year. Gastrointestinal diseases contribute significantly to health care costs and were recently estimated to be $135.9 billion annually. Innovation in gastroenterology has traditionally focused on expensive pharmaceuticals, devices, and new procedures. Many of the conditions and diseases treated byRead more …Innovation in a rural gastroenterology practice using a farm originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 9, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/savita-srivastava-and-christina-tennyson" rel="tag" > Savita Srivastava, MD and Christina Tennyson, MD < /a > < /span > Tags: Physician Gastroenterology Source Type: blogs
With Eyes to See and Ears to Beer: Navigating Multisensory Intellectual Property Rights in the Craft Beer Industry
Mark Edward Blankenship Jr. (Yeshiva University), With Eyes to See and Ears to Beer: Navigating Multisensory Intellectual Property Rights in the Craft Beer Industry, 21 Wake Forest J. Bus.& Intell. Prop. L. 395 (2021): Gastrophysics is an interdisciplinary science... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - December 6, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Insights From Our New E-book, The Medical Futurist ’s Hype Cycle Of The TOP 50 Digital Health Trends
As a researcher, I have always lived for the moments when I had to see a whole process and analyze the small details at once. Looking into the roots and origins of trends and also seeing the possible outcomes are rewarding in a way that I need to work with data (my passion), my analytical skills and my intuitions.
Besides, I’ve always loved challenging myself in order to be better – that is, for example, why I find my participation in undertakings like the Good Judgement Project (GJP) important.
So when we at The Medical Futurist decided to create a trend analysis of digital health trajectories, we ignited ...
Source: The Medical Futurist - December 2, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: TMF Covid-19 Lifestyle medicine 3D Printing Artificial Intelligence in Medicine Augmented Reality Digital Health Research Future of Medicine Future of Pharma Genomics Health Insurance Health Sensors & Trackers Healthcare Design M Source Type: blogs
Catheter-Deliverable Biomaterial Sealants: Interview with Natalie Artzi, Co-founder of BioDevek
BioDevek, a medtech company based in Cambridge, Massachusetts, has developed a biomaterial adhesive that acts to seal internal wounds and incisions. The material is designed to be sprayed through a catheter, and the primary application for the technology so far is to act as a sealant following colonic polyp resection.
At present, following polyp resection, surgeons can use polyp clips to seal the resection site, which can hamper wound healing, or use no sealant at all, leading to an open wound that comes with a risk of bleeding or other complications. This can lead to additional surgeries to correct the issue and is inc...
Source: Medgadget - November 30, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Materials Plastic Surgery BioDevek Source Type: blogs
Fight Aging! Newsletter, November 29th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - November 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Dogs Benefit from Time Restricted Feeding
A common factor in calorie restriction, intermittent fasting, and time-restricted feeding is time spent in a state of hunger. More time spent hungry may be better, up to a point. The signaling associated with hunger upregulates cellular maintenance processes such as autophagy, known to improve health over the long term. While the biochemistry is under ever greater exploration, there is still a lot of work to be accomplished in order to map the dose-response curve for calorie intake versus time spent hungry, as well as how that dose-response curve may differ in different mammalian species. One might look at recent discussio...
Source: Fight Aging! - November 22, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
How did we let insurers run health care?
How did we Americans allow health insurers to dictate how physicians practice good medicine? The hypocritic oath says,“Do no harm.” We should not allow insurance company profits to prevent proper care for patients. Our insurer is now telling our young adult son, a Crohn’s patient (Crohn’s is not yet a curable disease), who hasRead more …How did we let insurers run health care? originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 15, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/gary-lawson-and-marcia-lawson" rel="tag" > Gary Lawson and Marcia Lawson < /a > < /span > Tags: Meds Gastroenterology Medications Public Health & Policy Source Type: blogs
Chip for Investigation of Coronavirus Intestinal Infection
This study demonstrates that we can explore complex interactions between cells, pathogens, and drugs in the human intestine using our Intestine Chip as a preclinical model,” said Don Ingber, a researcher involved in the study, via a press release. “We hope it proves useful in the ongoing effort to better understand the effects of SARS-CoV-2 and to identify drugs that could be used to combat future viral pandemics.”
Study in Frontiers in Pharmacology: Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip
Flashbacks: Intestine Chip to Study Human-Microbiome Interact...
Source: Medgadget - November 10, 2021 Category: Medical Devices Authors: Conn Hastings Tags: GI Medicine Public Health Source Type: blogs
