Mechanisms by which Calorie Restriction Delays the Onset of Sarcopenia
In this study, except for the reduction in body weight, the aging characteristics related to epidermal and muscle tissue in mice were significantly ameliorated in the CR group compared with the control group. Additional studies have indicated that not stem cells themselves but the stem cell microenvironment is the key factor mediating stem cell activation, proliferation and differentiation. Mitochondrial dysfunction is an important factor leading to age-related muscular atrophy. Considering the dependence of skeletal muscle on ATP, loss of mitochondrial function, which can lead to a decrease in strength and enduranc...
Source: Fight Aging! - December 4, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

21st century outbreaks
  Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century?  In this blog, we can use GIDEON’s data to find out. ‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines,  and can sometimes go unnoticed outside of the Healthcare Industry. An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and...
Source: GIDEON blog - December 3, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs

Top 10 most prominent diseases of the 21st Century
Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century?  In this blog, we can use GIDEON’s data to find out. ‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines,  and can sometimes go unnoticed outside of the Healthcare Industry. An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and time. ...
Source: GIDEON blog - December 1, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs

Delayed GI Symptoms and a Liver Transplant
​A 16-year-old boy presented to an emergency department in rural Pennsylvania for nausea, vomiting, and diarrhea. He reported diffuse abdominal cramping that had started two hours earlier. Shortly prior to arrival, he had multiple episodes of nonbloody diarrhea and emesis. He had no significant past medical history, and was not currently taking any medications or supplements. Initially, the history he gave was limited due to a language barrier. His sister was also being evaluated for similar symptoms.The boy's vital signs were a heart rate of 130 bpm, a blood pressure of 100/50 mm Hg, a respiratory rate of 26 bpm, an oxy...
Source: The Tox Cave - November 30, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

What my locums tenens experience in Maine taught me
Recently I had the opportunity to work as a locums tenens physician in a small town in Maine, and it helped me gain a new perspective on community, health care, and living.   While providing a service to the area, I received valuable lessons in return.  The folks in Maine can teach the rest of the […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 24, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/christina-tennyson" rel="tag" > Christina Tennyson, MD < /a > < /span > Tags: Physician Gastroenterology Practice Management Source Type: blogs

From 5 Questions to 5 Reflections: A Residency Leadership “Sign-Out” During COVID-19—Part 2
Editor’s note: This is the second of a 2-part blog post. Read the first part of this blog post, with an introduction and the first 3 reflections, here. 4. A crisis reveals the flaws of how we assign value. Scholarly output is an important part of what we do in academic medicine. We balance the tasks of running our program, caring for patients, and teaching with individual pursuits: research, curriculum development, implementation science, or quality improvement. During the pandemic, many of these academic efforts were necessarily placed on hold. This impacted some more than others, along the predictable lines of ge...
Source: Academic Medicine Blog - November 17, 2020 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective COVID-19 leadership residency Source Type: blogs

From 5 Questions to 5 Reflections: A Residency Leadership “Sign-Out” During COVID-19—Part 1
Editor’s note: This is the first of a two-part blog post. Check back next week for the second-part of this blog post with the final 2 reflections.  As a chief resident and program director in our internal medicine residency program, we set out at the end of academic year 2019–2020 to prepare the annual sign-out for the incoming chief medical residents and launch a new academic year. This exercise is typically straightforward, a practice refined over years of repetition. However, this academic year had been defined by the sentinel crisis of the entire medical enterprise: the COVID-19 pandemic. In this two-part blog ...
Source: Academic Medicine Blog - November 10, 2020 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective COVID-19 leadership residency Source Type: blogs

Coping With IBS
Irritable bowel syndrome (IBS) can be painful, annoying, and embarrassing. There is currently no cure for this complex condition, and managing its symptoms and flare-ups is tricky. So, coping mechanisms are a constant need. What are the symptoms of IBS? IBS is a gastrointestinal disorder in which your gut becomes more sensitive, and the muscles of your digestive system have abnormal contractions. People with IBS usually have abdominal pain along with frequent changes in bowel habits (diarrhea, constipation, or alternating between both). Other common symptoms include bloating and gas urge to move the bowels, but being unab...
Source: Harvard Health Blog - November 3, 2020 Category: Consumer Health News Authors: Matthew Solan Tags: Digestive Disorders Health Mental Health Stress Source Type: blogs

Portable Surgical Robot for Minimally Invasive Procedures: Interview with John Murphy, CEO of Virtual Incision
Virtual Incision, a company based in Lincoln, Nebraska, has developed the miniaturized in vivo robotic assistant (MIRA) platform to perform minimally invasive abdominal surgeries, such as colon resections. Conceived as a small and accessible surgical robotic support device, the miniaturized system is considerably less expensive than current robotic surgical platforms. MIRA is small enough to be easily transported and typically requires fewer incisions than larger and more complex surgical robots. The system can be inserted through a single midline umbilical incision in the abdomen. Strikingly, the device does not need s...
Source: Medgadget - November 2, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurosurgery Orthopedic Surgery Plastic Surgery Thoracic Surgery Urology Vascular Surgery intuitive surgical minimally invasive surgery virtual incision Source Type: blogs

Zoom is foie gras of the brain
The stuffing of things into organs for a desired effect, in this case, fattening a goose, is first recorded in Ancient Egypt and has since been used in multiple culinary traditions. It is now best known for French cuisine. What gastronomes desire animal welfare people abhor. The preferred method is to put more things (food) […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 28, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lester-gottesman" rel="tag" > Lester Gottesman, MD < /a > < /span > Tags: Physician Health IT Mobile health Source Type: blogs

Aspirin and breast cancer risk: How a wonder drug may become more wonderful
Aspirin has been called a wonder drug. And it’s easy to see why. It’s inexpensive, its side effects are well-known and generally minor. And since it was developed in the 1890s, it’s been shown to provide a number of potential benefits, such as relieving pain, bringing down a fever, and preventing heart attacks and strokes. Over the last 20 years or so, the list of aspirin’s potential benefits has been growing. And it might be about to get even longer: did you know that aspirin may lower your risk of several types of cancer? Studies of aspirin and cancer A number of studies suggest that aspirin can lower the risk of...
Source: Harvard Health Blog - October 23, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Breast Cancer Health Source Type: blogs

We are suffering from an epidemic of anger
The nation ’s racial upheaval, particularly vis a vis law enforcement, has shown us the value of the skill of de-escalation. A situation arises, and several outcomes are possible, although some are clearly preferred. The specific technique and approach utilized may determine the end result. A range of option s is often available. What can make these […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 17, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/michael-kirsch" rel="tag" > Michael Kirsch, MD < /a > < /span > Tags: Physician Gastroenterology Source Type: blogs

Early, tight control of Crohn ’s disease may have lasting benefits
The gastrointestinal (GI) tract is a remarkable organ: it resides on the inside of our bodies, but is regularly in contact with the outside world by virtue of what we ingest. It is quite incredible that the immune cells of the GI tract are not activated more regularly by the many foreign products it encounters every day. Only when the GI tract encounters an intruder that risks causing disease do the immune cells of the GI tract spring into action. That is, of course, under normal circumstances. In people with Crohn’s disease, the normally tolerant immune cells of the GI tract are activated without provocation, and this a...
Source: Harvard Health Blog - October 16, 2020 Category: Consumer Health News Authors: Sarah Flier, MD Tags: Digestive Disorders Source Type: blogs

Will Trump, Congressional Infections Boost Innovations For Covid-19 Survivors?
By MICHAEL MILLENSON When powerful politicians confront a life-threatening diagnosis, it can change policy priorities.  In addition to President Trump and a slew of top aides, five U.S. senators and 15 members of the House of Representatives have now tested positive or been presumed positive in tests for Covid-19 as of Oct. 5, according to a running tally by National Public Radio (NPR). In that light, the recent burst of coronavirus infections could accelerate three significant innovations affecting every Covid-19 survivor. 1) Post-Covid Clinics Even seemingly mild encounters with the coronavirus can tr...
Source: The Health Care Blog - October 15, 2020 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy OP-ED Politics Michael Millenson Source Type: blogs

Fermented Foods and Your Gut: Why They Are So Good for Your Health
Do you have more than the occasional abdominal upset? If you find yourself singing the Pepto-Bismol jingle most days, why not consider adding more fermented foods to your diet.  You don’t have to go to a fancy health food store to buy exotic-sounding ingredients. You probably have many staples in your pantry and fridge. Here’s the skinny on fermented foods and your gut and how they benefit your overall health.  What Is Fermentation?  You might think of the term “fermentation” in association with beer or wine. However, this food preparation method goes back thousands of years — as far as 60...
Source: PickTheBrain | Motivation and Self Improvement - October 13, 2020 Category: Consumer Health News Authors: Jennifer Landis Tags: diet featured health and fitness self-improvement fermented foods gut health self improvement Source Type: blogs