Why poor diets are contributing to a surge in colorectal cancer cases among young people
An alarming trend has emerged in my medical practice in recent years: I’m seeing more and more young adults with colorectal cancer. When I began practicing as a family physician 21 years ago, I never saw patients in their 40s and 50s with the disease, much less ones in their 30s. Now, I diagnose two Read more… Why poor diets are contributing to a surge in colorectal cancer cases among young people originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 26, 2023 Category: General Medicine Authors: Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs

Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved. Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing the Aging of the Gut Microbiome
Researchers here take a high level tour of what is known of age-related changes in the gut microbiome and how they influence health. Accumulating evidence shows a loss of beneficial populations that generate useful metabolites such as butyrate, accompanied by an increase in harmful populations that can provoke chronic inflammation. This is a likely a meaningful contribution to the onset and development age-related conditions, making it a priority to develop ways to reset the balance of populations in the gut microbiome. The best of the available approaches, given the evidence to date, is fecal microbiota transplantation fr...
Source: Fight Aging! - April 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Implementation May Be a Science, But, Alas, Medicine Remains an Art
By KIM BELLARD I’ve been working in healthcare for over forty (!) years now, in one form or another, but it wasn’t until this past week that I heard of implementation science.  Which, in a way, is sort of the problem healthcare has.  Granted, I’m not a doctor or other clinician, but everyone working in healthcare should be aware of, and thinking a lot about, “the scientific study of methods to promote the systematic uptake of research findings and other EBPs into routine practice, and, hence, to improve the quality and effectiveness of health services” (Bauer, et. al).  It took a JAMA article,...
Source: The Health Care Blog - April 11, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Health care tech Implementation Kim Bellard Source Type: blogs

What do people want from pain management?
The short answer is often “take my pain away” – and we’d be foolish to ignore the impact of pain intensity on distress and disability. At the same time there’s more than enough research showing that if treatment only emphasises pain intensity (1) it may not be achievable for many, especially if we take into account the small effect sizes on pain intensity from exercise, medications and psychological therapies; and (2) even if pain is reduced, it may not translate into improvements in daily life. The slightly more complex answer lies behind the desire to “take my pain away.” We n...
Source: HealthSkills Weblog - March 19, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Coping strategies Research Science in practice Occupational therapy pain management Therapeutic approaches Source Type: blogs

Yoga and self-care won ’t cure my Crohn ’ s disease
Inflation and rising interest rates have given way to a record high of $930.6 billion in credit card debt. I am among many people who have gone into credit card debt by spending too much on health and wellness. Several years ago, I was diagnosed with Crohn’s disease, a type of irritable bowel disease (IBD), which Read more… Yoga and self-care won’t cure my Crohn’s disease originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 19, 2023 Category: General Medicine Authors: Tags: Conditions Gastroenterology Source Type: blogs

Fight Aging! Newsletter, March 20th 2023
This study also provides the potential for de novo generation of complex organs in vivo. T Cells May Play a Role in the Brain Inflammation Characteristic of Neurodegenerative Conditions https://www.fightaging.org/archives/2023/03/t-cells-may-play-a-role-in-the-brain-inflammation-characteristic-of-neurodegenerative-conditions/ Alzheimer's disease, and other forms of neurodegenerative condition, are characterized by chronic inflammation in brain tissue. Unresolved inflammatory signaling is disruptive of tissue structure and function. Here, researchers provide evidence for T cells to become involved in thi...
Source: Fight Aging! - March 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lowered Dietary Phosphate Slows the Onset of Sarcopenia in Mice
Researchers here find that both reduced phosphate in the diet and use of a phosphate binding drug slow age-related loss of muscle mass in mice. It is an interesting result given the size of the effect. It has been proposed that high levels of phosphates observed in later life are relatively important in the constellation of many contributing mechanisms implicated in the onset of sarcopenia, the name given to this characteristic decline of muscle mass and strength. The data noted here seems a compelling demonstration of the point. Sarcopenia is defined by the progressive and generalized loss of muscle mass and func...
Source: Fight Aging! - March 15, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

CodaMetrix Closes $55M Series A to Autonomously Power Medical Coding, Boost Health System Revenue Cycles
Born out of Mass General Brigham, and led by healthtech veterans, CodaMetrix empowers health systems to use Artificial Intelligence to prevent revenue setbacks driven by manual coding inefficiencies Overhauling medical coding is now crucial for health systems grappling with physician burnout, billing backlogs and claim denials, skilled labor shortages, and a graying medical coding workforce AI-powered, multi-specialty, autonomous medical coding eliminates human intervention, reduces coding costs, improves coding quality and unlocks clinician capacity CodaMetrix, the leading AI technology platform transforming healthcare ...
Source: EMR and HIPAA - March 10, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT AI Artificial Intelligence Chris Scoggins CMX CodaMetrix CU Healthcare Innovation Fund EHR Electronic Health Record FCV Frist Cressey Ventures Hamid Tabatabaie Health IT Funding Health IT Funding Source Type: blogs

Semaglutide – the “ skinny jab ”
TL:DR – Semaglutide is known to US celebrities as the “skinny jab” and has apparently been the subject of a weight-loss craze. It has now been approved in the UK for weight-loss in the clinically obese. Semaglutide is a pharmaceutical that can help control the symptoms of Type 2 diabetes for which it was first used. The nickname, the “skinny jab” comes from the drug’s activity as an appetite suppressant used in helping overweight people and the obese reduce their body weight. It is sold under the brand names Ozempic, Wegovy and Rybelsus and was originally developed by Novo Nordisk in 20...
Source: David Bradley Sciencebase - Songs, Snaps, Science - March 8, 2023 Category: Science Authors: David Bradley Tags: Health and Medicine Obesity Source Type: blogs

What ’ s On Your Plate? Culinary Medicine as an Innovative Nutrition Education Model
On this episode of the Academic Medicine Podcast, guests Courtney Newman and Jaclyn Albin, MD, join host Toni Gallo to discuss culinary medicine and its role in teaching nutrition, nutrition counseling, and hands-on cooking skills to medical students. The conversation also covers how culinary medicine programs build connections and community and improve the well-being of students, faculty, and patients. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Read the article discussed in this episode: Newman C, Yan J, Me...
Source: Academic Medicine Blog - February 20, 2023 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast culinary medicine medical education nutrition patient care Source Type: blogs

Ingestible Sensor Reveals Gastric Motility
Researchers at MIT have developed an ingestible sensor that can reveal gastrointestinal motility issues, such as gastroparesis and gastroesophageal reflux disease. The technology is intended for use as an easy at-home method to diagnose such issues, which typically require more invasive and inconvenient procedures, such as endoscopy or X-ray imaging. This new technology is based on the concept that a magnetic field produced by an electromagnetic coil becomes weaker the further away you move from the coil. This change in field signal is predictable, allowing researchers to calculate the distance accurately by measuring the ...
Source: Medgadget - February 16, 2023 Category: Medical Devices Authors: Conn Hastings Tags: GI mit Source Type: blogs

Make Dry January a habit: Understanding and addressing alcohol use disorder
The concept of Dry January, an opportunity to take a break from alcohol, does not need to end on January 31. If it does end, dietary guidelines recommending a maximum of 1 drink or less for women and two drinks or less for men on any given day should guide subsequent alcohol use. This is because Read more… Make Dry January a habit: Understanding and addressing alcohol use disorder originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 14, 2023 Category: General Medicine Authors: Tags: Physician Gastroenterology Source Type: blogs

Practicing Medicine without a License: When Patients and Politicians Play Doctor
BY MICHAEL KIRSCH We’ve all heard the adage, leave it to the professionals.  It’s typically used when an individual has wandered out of his lane.  How many folks go beyond their knowledge and skills with home projects, for example, who must then hire a real professional to mop up the mistakes?  Luckily for me, the only tools that I – a gastroenterologist – know how to use are a colonoscope and an endoscope, so there’s no chance that I will be tempted to perform any plumbing or electrical tasks at home.   Although patients are not medical professionals, they routinely bring me results...
Source: The Health Care Blog - February 1, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Medical Marijuana Medical Practice medical professionals michael kirsch politicians Source Type: blogs

Why skipping your colonoscopy could be a deadly mistake
I have to respond to and correct the recent article and podcast about a doctor having his first colonoscopy in his late 60s without anesthesia. There were multiple factual errors and misstatements by the doctor author, which may well dissuade doctors and laypeople from colonoscopies in the future. First, he notes the reason he’s thus Read more… Why skipping your colonoscopy could be a deadly mistake originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 31, 2023 Category: General Medicine Authors: Tags: Conditions Gastroenterology Source Type: blogs