AI designs bespoke 3D-printed prosthetic eyes
Using an artificial intelligence model and 3D printer to create prosthetic eyes reduces the time required to make such implants, which could make them available to more people (Source: New Scientist - Health)
Source: New Scientist - Health - February 27, 2024 Category: Consumer Health News Source Type: research

Real-world experience with fluocinolone acetonide intravitreal implant in patients with diabetic macular edema
CONCLUSION: FAc implant provides a substantial long-term functional and anatomical benefit when used as second-line treatment in eyes with DME. IOP rise can be adequately managed with topical agents although some eyes may require IOP-lowering surgery.PMID:38396370 | DOI:10.1177/11206721241235266 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 24, 2024 Category: Opthalmology Authors: Luigi Capone Pietro Airaghi Pasquale Aragona Nicol ò Castellino Maria Vittoria Cicinelli Francesco Ciucci Michele Coppola Cristiano De Gaetano Rosangela Lattanzio Massimo Lorusso Martina Maceroni Maria Elena Malvasi Luisa Marco Michele Marraffa Gaia Mart Source Type: research

Real-world experience with fluocinolone acetonide intravitreal implant in patients with diabetic macular edema
CONCLUSION: FAc implant provides a substantial long-term functional and anatomical benefit when used as second-line treatment in eyes with DME. IOP rise can be adequately managed with topical agents although some eyes may require IOP-lowering surgery.PMID:38396370 | DOI:10.1177/11206721241235266 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 24, 2024 Category: Opthalmology Authors: Luigi Capone Pietro Airaghi Pasquale Aragona Nicol ò Castellino Maria Vittoria Cicinelli Francesco Ciucci Michele Coppola Cristiano De Gaetano Rosangela Lattanzio Massimo Lorusso Martina Maceroni Maria Elena Malvasi Luisa Marco Michele Marraffa Gaia Mart Source Type: research

Clinical and optical coherence tomography biomarkers as prognostic factors in dexamethasone intravitreal implant for diabetic macular edema
CONCLUSION: In conclusion, OCT biomarkers can be considered significant prognostic factors for treatment outcome in patients with DME undergoing DEX intravitreal implant.PMID:38384119 | DOI:10.1177/11206721241235242 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 22, 2024 Category: Opthalmology Authors: Giovanni William Oliverio Alessandro Meduri Valentina Urz ì Brancati Irene Ingrande Laura De Luca Enrico Di Raimondo Letteria Minutoli Emanuela Aragona Pasquale Aragona Source Type: research

Clinical and optical coherence tomography biomarkers as prognostic factors in dexamethasone intravitreal implant for diabetic macular edema
CONCLUSION: In conclusion, OCT biomarkers can be considered significant prognostic factors for treatment outcome in patients with DME undergoing DEX intravitreal implant.PMID:38384119 | DOI:10.1177/11206721241235242 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 22, 2024 Category: Opthalmology Authors: Giovanni William Oliverio Alessandro Meduri Valentina Urz ì Brancati Irene Ingrande Laura De Luca Enrico Di Raimondo Letteria Minutoli Emanuela Aragona Pasquale Aragona Source Type: research

Postural impairments in unilateral and bilateral vestibulopathy
Chronic imbalance is a major complaint of patients suffering from bilateral vestibulopathy (BV) and is often reported by patients with chronic unilateral vestibulopathy (UV), leading to increased risk of falling. We used the Central SensoriMotor Integration (CSMI) test, which evaluates sensory integration, time delay, and motor activation contributions to standing balance control, to determine whether CSMI measures could distinguish between healthy control (HC), UV, and BV subjects and to characterize vestibular, proprioceptive, and visual contributions expressed as sensory weights. We also hypothesized that sensory weight...
Source: Frontiers in Neurology - February 21, 2024 Category: Neurology Source Type: research

Epiretinal membrane development after Ex-Press glaucoma filtration device implant: 2-year results of a case control study
ConclusionEx-Press implant may increase the ERM incidence regardless concomitant cataract surgery, accelerating or inducing a posterior vitreous detachment, such as other ocular surgical procedure. Nevertheless, the vast majority of ERM are CMR, not affecting the macular profile. (Source: International Ophthalmology)
Source: International Ophthalmology - February 17, 2024 Category: Opthalmology Source Type: research

M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling
CONCLUSIONS: TGF-β1/Smad2/3-YAP/TAZ signalling may be involved in M2-induced fibrotic activities in HTFs. M2 plays a key role in promoting subconjunctival fibrosis and can serve as an attractive target for anti-fibrotic therapeutics.PMID:38335557 | PMC:PMC10860428 | DOI:10.1080/07853890.2024.2313680 (Source: Annals of Medicine)
Source: Annals of Medicine - February 9, 2024 Category: Internal Medicine Authors: Yiwei Wang Xingchen Geng Zhihua Guo Dandan Chu Ruixing Liu Boyuan Cheng Haohao Cui Chengcheng Li Jingguo Li Zhanrong Li Source Type: research

Does dexamethasone implant combination with aflibercept monotherapy affect one-year outcomes in treatment-naive diabetic macular edema with inflammatory biomarkers?
ConclusionThe CT, where inflammation is prominent, can provide faster recovery. The pseudophakic eyes seem to be the ideal patient group for CT. (Source: International Ophthalmology)
Source: International Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research

Long-Term Surgical Outcomes of Glaucoma Drainage Implants in Eyes with Preoperative Intraocular Pressure Less than 19  mmHg
CONCLUSION: In patients with baseline IOP ≤18 mmHg who had GDI surgery, though the change in IOP was not statistically significant, the number of medications dropped and visual field progression slowed in a subset of patients with adequate perimetric data. Due to a relatively high rate of complications and limited effectiveness in lowering IOP, GDI should be cautiously used in these eyes.PMID:38304290 | PMC:PMC10830923 | DOI:10.1155/2024/6624021 (Source: Journal of Ophthalmology)
Source: Journal of Ophthalmology - February 2, 2024 Category: Opthalmology Authors: Shahin Hallaj Jae-Chiang Wong Lauren E Hock Natasha Nayak Kolomeyer Aakriti G Shukla Michael J Pro Marlene R Moster Jonathan S Myers Reza Razeghinejad Daniel Lee Source Type: research

Anatomical and Functional Results of Early or Late Switching from Anti-VEGF to Dexamethasone Implant in Case of Poor Anatomical Response in Na ïve Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion
CONCLUSIONS: A gain of 15 or more letters was demonstrated to be higher in patients who switched to DEX implant late after anti-VEGF treatment. If it is necessary to switch, the late switch may be more effective for more visual gain at the end of the first year.PMID:38282256 | DOI:10.1080/08820538.2024.2310662 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - January 29, 2024 Category: Opthalmology Authors: Z übeyir Yozgat Mehmed U ğur Işik Source Type: research

Safety and effectiveness of intravitreal dexamethasone implant in patients with ocular toxocariasis
Conclusions This was the first study to investigate use of intravitreal DEX implant in OT patients, which can efficiently reduce ocular inflammation and improve BCVA in macular uninvolved patients. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 29, 2024 Category: Opthalmology Authors: Sun, L., Huang, L., Li, S., Lu, J., Zheng, S., Ding, X. Tags: Intraocular infection and inflammation Source Type: research

Outcomes for expanded polytetrafluoroethylene strip in frontalis suspension surgery
CONCLUSION: An ePTFE strip soaked in cefazolin prior to utilization in surgery is a viable material for frontalis suspension surgery, with a lower infectious or inflammatory complication rate than previously reported. However, reoperation rate was still relatively high.PMID:38236954 | DOI:10.1080/01676830.2023.2300793 (Source: Orbit)
Source: Orbit - January 18, 2024 Category: Opthalmology Authors: Elana Meer Meleha Ahmad Jacob Lifton Arman Mosenia Davin C Ashraf Seanna Grob M Reza Vagefi Bryan J Winn Robert C Kersten Source Type: research

Influence of prior treatment protocol on intravitreal dexamethasone implant behavior in patients with diabetic macular edema in real-world practice
CONCLUSIONS: There was similar anatomical and functional behavior in all groups. Poorer visual acuity at baseline was associated with worse functional outcome despite good anatomic response.PMID:38234187 | DOI:10.1080/14740338.2024.2305361 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - January 18, 2024 Category: Drugs & Pharmacology Authors: Almudena Moreno-Martinez Cristina Blanco-Marchite Sergio Copete Source Type: research

Long-Term Clinical Outcomes of the 0.18 Mg Fluocinolone Acetonide Intravitreal Implant Following Local Corticosteroid Burst in Noninfectious Uveitis
CONCLUSIONS: This treatment approach demonstrates that the 0.18 mg FAi is a useful adjuvant for the treatment of noninfectious uveitis but may not be adequate as solo therapy.PMID:38194443 | DOI:10.1080/09273948.2023.2296031 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Timothy M Janetos Anjum Koreishi Debra A Goldstein Source Type: research