Efficacy of 190 mcg fluocinolone acetonide intravitreal implant: microperimetry and OCT real-life data
CONCLUSIONS: According to the results of our study, fluocinolone acetonide (FAc) is a valid therapy option despite some limitations. It has been evidenced that FAc is more effective in patients with mild central macular thickening, while in those with modest to severe central macular thickness (CMT), different therapy strategies should be considered.PMID:36930491 | DOI:10.26355/eurrev_202303_31536 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 17, 2023 Category: Drugs & Pharmacology Authors: F Avogaro A Florido A Calandri F Toja E M Vingolo Source Type: research
Efficacy of 190 mcg fluocinolone acetonide intravitreal implant: microperimetry and OCT real-life data
CONCLUSIONS: According to the results of our study, fluocinolone acetonide (FAc) is a valid therapy option despite some limitations. It has been evidenced that FAc is more effective in patients with mild central macular thickening, while in those with modest to severe central macular thickness (CMT), different therapy strategies should be considered.PMID:36930491 | DOI:10.26355/eurrev_202303_31536 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 17, 2023 Category: Drugs & Pharmacology Authors: F Avogaro A Florido A Calandri F Toja E M Vingolo Source Type: research
Intravitreal dexamethasone to manage post endothelial keratoplasty cystoid macular oedema refractory to topical therapy
CONCLUSIONS: The use of intravitreal sustained-release dexamethasone implant in the management of post EK CMO refractory to topical therapy is effective and safe in most cases, but patients should be monitored and treated promptly for any secondary IOP response.PMID:36919243 | DOI:10.1177/11206721231160983 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - March 15, 2023 Category: Opthalmology Authors: Jesse Panthagani Elizabeth M Law Caroline Wong Chimwemwe Chipeta Harry Roberts James Myerscough Source Type: research
Cosmetic iris implants - double edge sword
Eur J Ophthalmol. 2023 Feb 27:11206721231160989. doi: 10.1177/11206721231160989. Online ahead of print.ABSTRACTIris implants were originally described as an option to treat photophobia and glare associated with aniridia, coloboma, corectopia or any other causes of acquired or congenital iris defects. They are not designed to be used in healthy phakic eyes and not approved by regulatory bodies anywhere in the world for cosmesis. However, widespread publicity and the compulsive need for beautification has popularised the use of these implants illicitly. Implantation into phakic eyes causes mechanical irritation of angle stru...
Source: European Journal of Ophthalmology - February 28, 2023 Category: Opthalmology Authors: Tulika Chauhan Isha Chaturvedi Kanika Bhardwaj Yuganki Kush Garvita Dabas Krishna Teja Source Type: research
Cosmetic iris implants - double edge sword
Eur J Ophthalmol. 2023 Feb 27:11206721231160989. doi: 10.1177/11206721231160989. Online ahead of print.ABSTRACTIris implants were originally described as an option to treat photophobia and glare associated with aniridia, coloboma, corectopia or any other causes of acquired or congenital iris defects. They are not designed to be used in healthy phakic eyes and not approved by regulatory bodies anywhere in the world for cosmesis. However, widespread publicity and the compulsive need for beautification has popularised the use of these implants illicitly. Implantation into phakic eyes causes mechanical irritation of angle stru...
Source: European Journal of Ophthalmology - February 28, 2023 Category: Opthalmology Authors: Tulika Chauhan Isha Chaturvedi Kanika Bhardwaj Yuganki Kush Garvita Dabas Krishna Teja Source Type: research
Prognostic Imaging Biomarkers in Diabetic Macular Edema Eyes Treated with Intravitreal Dexamethasone Implant
CONCLUSION: The presence of DME mixed pattern, a high number of parafoveal HRF, hyper-reflective MAs, SSPiM in the outer nuclear layers, and high PD represent baseline predictive biomarkers for DEXi treatment responsiveness. The application of these models to treatment-naïve patients allowed a good identification of n-RES eyes.PMID:36835839 | DOI:10.3390/jcm12041303 (Source: Clin Med Res)
Source: Clin Med Res - February 25, 2023 Category: Research Authors: Eliana Costanzo Daniela Giannini Daniele De Geronimo Serena Fragiotta Monica Varano Mariacristina Parravano Source Type: research
Prognostic Imaging Biomarkers in Diabetic Macular Edema Eyes Treated with Intravitreal Dexamethasone Implant
CONCLUSION: The presence of DME mixed pattern, a high number of parafoveal HRF, hyper-reflective MAs, SSPiM in the outer nuclear layers, and high PD represent baseline predictive biomarkers for DEXi treatment responsiveness. The application of these models to treatment-naïve patients allowed a good identification of n-RES eyes.PMID:36835839 | DOI:10.3390/jcm12041303 (Source: Clin Med Res)
Source: Clin Med Res - February 25, 2023 Category: Research Authors: Eliana Costanzo Daniela Giannini Daniele De Geronimo Serena Fragiotta Monica Varano Mariacristina Parravano Source Type: research
IJERPH, Vol. 20, Pages 4152: Comparison of Safety and Efficacy of Hydrus and iStent Combined with Phacoemulsyfication in Open Angle Glaucoma Patients: 24-Month Follow-Up
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The paper presents the results of a 24-month-long observation comparing the effectiveness and safety of two micro-invasive glaucoma surgery (MIGS) devices: Hydrus Microstent and iStent Trabecular Bypass in combination with cataract phacoemulsification in the treatment of open-angle glaucoma. We also analyzed the impact of preoperative factors on achieving surgical success in both surgical methods. The prospective, comparative, non-randomized study included 65 glaucoma surgeries. In 35 patients (53.8%), an iStent implant procedure was performed, while 30 patients (46.2%) underwent a Hydrus implant procedure. The dem...
Source: International Journal of Environmental Research and Public Health - February 25, 2023 Category: Environmental Health Authors: Joanna Jab łońska Katarzyna Lewczuk Marek Tadeusz R ękas Tags: Article Source Type: research
Preconditioning of clinical data for intraocular lens formula constant optimisation using Random Forest Quantile Regression Trees
CONCLUSION: We were able to prove that with random forest quantile regression trees a fully data driven outlier identification strategy acting in the response space is achievable. In a real life scenario this strategy has to be complemented by an outlier identification method acting in the parameter space for a proper qualification of datasets prior to formula constant optimisation.PMID:36813595 | DOI:10.1016/j.zemedi.2022.11.009 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - February 22, 2023 Category: Radiology Authors: Achim Langenbucher N óra Szentmáry Alan Cayless Jascha Wendelstein Peter Hoffmann Source Type: research
Preconditioning of clinical data for intraocular lens formula constant optimisation using Random Forest Quantile Regression Trees
CONCLUSION: We were able to prove that with random forest quantile regression trees a fully data driven outlier identification strategy acting in the response space is achievable. In a real life scenario this strategy has to be complemented by an outlier identification method acting in the parameter space for a proper qualification of datasets prior to formula constant optimisation.PMID:36813595 | DOI:10.1016/j.zemedi.2022.11.009 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - February 22, 2023 Category: Radiology Authors: Achim Langenbucher N óra Szentmáry Alan Cayless Jascha Wendelstein Peter Hoffmann Source Type: research
Preconditioning of clinical data for intraocular lens formula constant optimisation using Random Forest Quantile Regression Trees
CONCLUSION: We were able to prove that with random forest quantile regression trees a fully data driven outlier identification strategy acting in the response space is achievable. In a real life scenario this strategy has to be complemented by an outlier identification method acting in the parameter space for a proper qualification of datasets prior to formula constant optimisation.PMID:36813595 | DOI:10.1016/j.zemedi.2022.11.009 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - February 22, 2023 Category: Radiology Authors: Achim Langenbucher N óra Szentmáry Alan Cayless Jascha Wendelstein Peter Hoffmann Source Type: research
