M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling

CONCLUSIONS: TGF-β1/Smad2/3-YAP/TAZ signalling may be involved in M2-induced fibrotic activities in HTFs. M2 plays a key role in promoting subconjunctival fibrosis and can serve as an attractive target for anti-fibrotic therapeutics.PMID:38335557 | PMC:PMC10860428 | DOI:10.1080/07853890.2024.2313680

Source: Annals of Medicine - February 9, 2024 Category: Internal Medicine Authors: Yiwei Wang Xingchen Geng Zhihua Guo Dandan Chu Ruixing Liu Boyuan Cheng Haohao Cui Chengcheng Li Jingguo Li Zhanrong Li Source Type: research