Association between leucocyte telomere length and erectile dysfunction in US adults: a secondary study based on 2001-2002 NHANES data
Conclusion Our results demonstrated an inverted J-curve relationship between the LTL and ED. When the LTL was ≥1.037, the incidence of ED decreased with increasing LTL. (Source: BMJ Open)
Source: BMJ Open - April 19, 2024 Category: General Medicine Authors: Dilixiati, D., Kadier, K., Laihaiti, D., Lu, J.-D., Azhati, B., Rexiati, M. Tags: Open access, Urology Source Type: research

Anxiety, depression, urinary continence, and sexuality in patients undergoing radical prostatectomy: preliminary findings
ConclusionsIn the early post-surgical phase anxiety and ED are the most frequently detected components, while depressive experiences and decreased desire, typical of later stages, have not yet fully emerged. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research

Health-related quality of life following salvage radical prostatectomy for recurrent prostate cancer after radiotherapy or focal therapy
ConclusionssRP impacts HRQOL in patients with PCa after RT and FT with no significant differences. Comparison with HRQOL and BRFS of treatment alternatives is paramount to counsel patients for appropriate treatments. (Source: World Journal of Urology)
Source: World Journal of Urology - April 18, 2024 Category: Urology & Nephrology Source Type: research

Aortoiliac occlusion mimicking cauda equina syndrome, a diagnostic dilemma: A case report and review of the literature
CONCLUSION: For patients presenting with cauda equina symptomatology, it is critical to consider vascular etiology, especially for those with cardiovascular risk factors. Spine surgeons and emergency physicians should maintain a high index of suspicion for vascular etiologies and consider appropriate imaging studies to promote early diagnosis and intervention to prevent subsequent neurological and life-threatening consequences.PMID:38628528 | PMC:PMC11021084 | DOI:10.25259/SNI_1011_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Abdulaziz Alomayri Ali A Basalamah Alwaleed Abdulrahman Alsaleh Sultan Alreshood Abdulrahman Aldakkan Source Type: research

Association between atherogenic indexes and erectile dysfunction: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004
CONCLUSIONS: AIP is positively associated with the development of ED in US adults. More prospective cohort studies are needed to confirm the link between AIP and ED.PMID:38625648 | DOI:10.1007/s11255-024-04050-4 (Source: Atherosclerosis)
Source: Atherosclerosis - April 16, 2024 Category: Cardiology Authors: Lange Guo Yukui Nan Lizhong Yao Source Type: research

Association between atherogenic indexes and erectile dysfunction: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004
CONCLUSIONS: AIP is positively associated with the development of ED in US adults. More prospective cohort studies are needed to confirm the link between AIP and ED.PMID:38625648 | DOI:10.1007/s11255-024-04050-4 (Source: Atherosclerosis)
Source: Atherosclerosis - April 16, 2024 Category: Cardiology Authors: Lange Guo Yukui Nan Lizhong Yao Source Type: research

Response to Comment on: Platelet-rich plasma intracavernosal injections for the treatment of primary organic erectile dysfunction: a systematic review and meta-analysis of contemporary controlled studies
International Journal of Impotence Research, Published online: 15 April 2024; doi:10.1038/s41443-024-00878-7Response to Comment on: Platelet-rich plasma intracavernosal injections for the treatment of primary organic erectile dysfunction: a systematic review and meta-analysis of contemporary controlled studies (Source: International Journal of Impotence Research)
Source: International Journal of Impotence Research - April 15, 2024 Category: Urology & Nephrology Authors: Andrea Panunzio Alessandro Tafuri Source Type: research

Possible Retinotoxicity of Long-term Vardenafil Treatment
Exp Eye Res. 2024 Apr 12:109890. doi: 10.1016/j.exer.2024.109890. Online ahead of print.ABSTRACTPhosphodiesterase (PDE) inhibitors - such as vardenafil - are used primarily for treating erectile dysfunction via increasing cyclic guanosine monophosphate (cGMP) levels. Recent studies have also demonstrated their significant cardioprotective effects in several diseases, including diabetes, upon long-term, continuous application. However, PDE inhibitors are not specific for PDE5 and also inhibit the retinal isoform. A sustained rise in cGMP in photoreceptors is known to be toxic; therefore, we hypothesized that long-term varde...
Source: Cell Research - April 14, 2024 Category: Cytology Authors: Klaudia Szab ó Bulcs ú Dékány Anna Énzsöly Rozina Ida Hajd ú Lenke Korn élia Laurik-Feuerstein Arnold Szab ó Tam ás Radovits Csaba M átyás Attila Ol áh Kriszti án András Kovács Ágoston Szél G ábor Márk Somfai Ákos Lukáts Source Type: research

Possible Retinotoxicity of Long-term Vardenafil Treatment
Exp Eye Res. 2024 Apr 12:109890. doi: 10.1016/j.exer.2024.109890. Online ahead of print.ABSTRACTPhosphodiesterase (PDE) inhibitors - such as vardenafil - are used primarily for treating erectile dysfunction via increasing cyclic guanosine monophosphate (cGMP) levels. Recent studies have also demonstrated their significant cardioprotective effects in several diseases, including diabetes, upon long-term, continuous application. However, PDE inhibitors are not specific for PDE5 and also inhibit the retinal isoform. A sustained rise in cGMP in photoreceptors is known to be toxic; therefore, we hypothesized that long-term varde...
Source: Experimental Eye Research - April 14, 2024 Category: Opthalmology Authors: Klaudia Szab ó Bulcs ú Dékány Anna Énzsöly Rozina Ida Hajd ú Lenke Korn élia Laurik-Feuerstein Arnold Szab ó Tam ás Radovits Csaba M átyás Attila Ol áh Kriszti án András Kovács Ágoston Szél G ábor Márk Somfai Ákos Lukáts Source Type: research