Anxiety, depression, urinary continence, and sexuality in patients undergoing radical prostatectomy: preliminary findings
ConclusionsIn the early post-surgical phase anxiety and ED are the most frequently detected components, while depressive experiences and decreased desire, typical of later stages, have not yet fully emerged. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research
Aortoiliac occlusion mimicking cauda equina syndrome, a diagnostic dilemma: A case report and review of the literature
CONCLUSION: For patients presenting with cauda equina symptomatology, it is critical to consider vascular etiology, especially for those with cardiovascular risk factors. Spine surgeons and emergency physicians should maintain a high index of suspicion for vascular etiologies and consider appropriate imaging studies to promote early diagnosis and intervention to prevent subsequent neurological and life-threatening consequences.PMID:38628528 | PMC:PMC11021084 | DOI:10.25259/SNI_1011_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Abdulaziz Alomayri Ali A Basalamah Alwaleed Abdulrahman Alsaleh Sultan Alreshood Abdulrahman Aldakkan Source Type: research
Association between atherogenic indexes and erectile dysfunction: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004
CONCLUSIONS: AIP is positively associated with the development of ED in US adults. More prospective cohort studies are needed to confirm the link between AIP and ED.PMID:38625648 | DOI:10.1007/s11255-024-04050-4 (Source: Atherosclerosis)
Source: Atherosclerosis - April 16, 2024 Category: Cardiology Authors: Lange Guo Yukui Nan Lizhong Yao Source Type: research
Association between atherogenic indexes and erectile dysfunction: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004
CONCLUSIONS: AIP is positively associated with the development of ED in US adults. More prospective cohort studies are needed to confirm the link between AIP and ED.PMID:38625648 | DOI:10.1007/s11255-024-04050-4 (Source: Atherosclerosis)
Source: Atherosclerosis - April 16, 2024 Category: Cardiology Authors: Lange Guo Yukui Nan Lizhong Yao Source Type: research
Response to Comment on: Platelet-rich plasma intracavernosal injections for the treatment of primary organic erectile dysfunction: a systematic review and meta-analysis of contemporary controlled studies
International Journal of Impotence Research, Published online: 15 April 2024; doi:10.1038/s41443-024-00878-7Response to Comment on: Platelet-rich plasma intracavernosal injections for the treatment of primary organic erectile dysfunction: a systematic review and meta-analysis of contemporary controlled studies (Source: International Journal of Impotence Research)
Source: International Journal of Impotence Research - April 15, 2024 Category: Urology & Nephrology Authors: Andrea Panunzio Alessandro Tafuri Source Type: research
Possible Retinotoxicity of Long-term Vardenafil Treatment
Exp Eye Res. 2024 Apr 12:109890. doi: 10.1016/j.exer.2024.109890. Online ahead of print.ABSTRACTPhosphodiesterase (PDE) inhibitors - such as vardenafil - are used primarily for treating erectile dysfunction via increasing cyclic guanosine monophosphate (cGMP) levels. Recent studies have also demonstrated their significant cardioprotective effects in several diseases, including diabetes, upon long-term, continuous application. However, PDE inhibitors are not specific for PDE5 and also inhibit the retinal isoform. A sustained rise in cGMP in photoreceptors is known to be toxic; therefore, we hypothesized that long-term varde...
Source: Cell Research - April 14, 2024 Category: Cytology Authors: Klaudia Szab ó Bulcs ú Dékány Anna Énzsöly Rozina Ida Hajd ú Lenke Korn élia Laurik-Feuerstein Arnold Szab ó Tam ás Radovits Csaba M átyás Attila Ol áh Kriszti án András Kovács Ágoston Szél G ábor Márk Somfai Ákos Lukáts Source Type: research
Possible Retinotoxicity of Long-term Vardenafil Treatment
Exp Eye Res. 2024 Apr 12:109890. doi: 10.1016/j.exer.2024.109890. Online ahead of print.ABSTRACTPhosphodiesterase (PDE) inhibitors - such as vardenafil - are used primarily for treating erectile dysfunction via increasing cyclic guanosine monophosphate (cGMP) levels. Recent studies have also demonstrated their significant cardioprotective effects in several diseases, including diabetes, upon long-term, continuous application. However, PDE inhibitors are not specific for PDE5 and also inhibit the retinal isoform. A sustained rise in cGMP in photoreceptors is known to be toxic; therefore, we hypothesized that long-term varde...
Source: Experimental Eye Research - April 14, 2024 Category: Opthalmology Authors: Klaudia Szab ó Bulcs ú Dékány Anna Énzsöly Rozina Ida Hajd ú Lenke Korn élia Laurik-Feuerstein Arnold Szab ó Tam ás Radovits Csaba M átyás Attila Ol áh Kriszti án András Kovács Ágoston Szél G ábor Márk Somfai Ákos Lukáts Source Type: research
Association between severe headache or migraine and erectile dysfunction in American adults: a cross-sectional of data study from the NHANES
International Journal of Impotence Research, Published online: 12 April 2024; doi:10.1038/s41443-024-00867-wAssociation between severe headache or migraine and erectile dysfunction in American adults: a cross-sectional of data study from the NHANES (Source: International Journal of Impotence Research)
Source: International Journal of Impotence Research - April 12, 2024 Category: Urology & Nephrology Authors: Xu Wu Yuyang Zhang Guodong Liu Hui Jiang Xiansheng Zhang Source Type: research
Exploring Trends in Erectile Dysfunction Research from 2017 to 2023: A Focus on COVID-19, Mental Health, Psychiatry, and Drug
AbstractThis paper investigates the trends in erectile dysfunction research by integrating individual keywords such as COVID-19, mental health, psychiatry, and drug use. The study spans a six-year period from September 21, 2017, to September 21, 2023, and utilizes resources from the National Library of Medicine. For instance, the quantity of relevant documents is determined using the Google search engine. A custom date range can be set on the browser via tools, and the search is limited to the nih.gov site domain. The phrase-site search command used is executed with “erectile dysfunction” COVID-19 site:nih.gov. The res...
Source: Sexuality and Disability - April 12, 2024 Category: Disability Source Type: research
Costs associated with adverse events during treatment episodes for adult attention-deficit/hyperactivity disorder
Conclusions: This study found that AEs occurring during ADHD treatment episodes are associated with significant healthcare costs. This highlights the potential of treatments with favorable safety profiles to alleviate the burden experienced by patients and the healthcare system.PMID:38602691 | DOI:10.1080/13696998.2024.2342749 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 11, 2024 Category: Health Management Authors: Jeff Schein Martin Cloutier Rebecca Bungay Marjolaine Gauthier-Loiselle Ann Childress Source Type: research
β-blockers are not all the same: pharmacologic similarities and differences, potential combinations and clinical implications
Curr Med Res Opin. 2024;40(sup1):15-23. doi: 10.1080/03007995.2024.2318058. Epub 2024 Apr 10.ABSTRACTβ-blockers are a heterogeneous class, with individual agents distinguished by selectivity for β1- vs. β2- and α-adrenoceptors, presence or absence of partial agonist activity at one of more β-receptor subtype, presence or absence of additional vasodilatory properties, and lipophilicity, which determines the ease of entry the drug into the central nervous system. Cardioselectivity (β1-adrenoceptor selectivity) helps to reduce the potential for adverse effects mediated by blockade of β2-adrenoceptors outside the myocar...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Stefano Taddei Nqoba Tsabedze Ru-San Tan Source Type: research
Safety and tolerability of β-blockers: importance of cardioselectivity
Curr Med Res Opin. 2024;40(sup1):55-62. doi: 10.1080/03007995.2024.2317433. Epub 2024 Apr 10.ABSTRACTCardioselective β-blockade is generally well tolerated in practice and contraindications to this therapy are uncommon. β-blockers are a diverse therapeutic class, and their individual tolerability profiles are influenced strongly by their pharmacodynamic effects across different adrenergic receptors. Bisoprolol, probably the β-blocker with the highest selectivity for blockade of β1- vs. β2-adrenoceptors, does not block β2-adrenoceptors to an appreciable extent at doses in therapeutic use. Side-effects often attributed...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Hans-Peter Marti Abel Alberto Pav ía López Pedro Schwartzmann Source Type: research
Erectile function preservation after radiotherapy using a dose-optimization approach on sexual structures for localized prostate cancer
CONCLUSION: This approach with dose-optimization on sexual structures for localized prostate cancer found excellent results on erectile function preservation after radiotherapy, with 78% of the patients with no or mild erectile dysfunction at 2 years.PMID:38599939 | DOI:10.1016/j.canrad.2023.08.010 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - April 10, 2024 Category: Cancer & Oncology Authors: A Chardon C Udrescu A Beneux A Ruffion S Horn A Lapierre O Chapet Source Type: research
β-blockers are not all the same: pharmacologic similarities and differences, potential combinations and clinical implications
Curr Med Res Opin. 2024;40(sup1):15-23. doi: 10.1080/03007995.2024.2318058. Epub 2024 Apr 10.ABSTRACTβ-blockers are a heterogeneous class, with individual agents distinguished by selectivity for β1- vs. β2- and α-adrenoceptors, presence or absence of partial agonist activity at one of more β-receptor subtype, presence or absence of additional vasodilatory properties, and lipophilicity, which determines the ease of entry the drug into the central nervous system. Cardioselectivity (β1-adrenoceptor selectivity) helps to reduce the potential for adverse effects mediated by blockade of β2-adrenoceptors outside the myocar...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Stefano Taddei Nqoba Tsabedze Ru-San Tan Source Type: research
