Philadelphia ’ s devastating gun violence epidemic: a wake-up call for action
It’s become my morning ritual on the way to the hospital. Cruising down a main Philadelphia stretch, just as the road crests and the hospital becomes visible, I steel myself for the line. Is it going to be long today? In just a few more blocks, my second reflexive check-in: Are there news vans outside Read more… Philadelphia’s devastating gun violence epidemic: a wake-up call for action originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 4, 2023 Category: General Medicine Authors: Tags: Policy Public Health & Policy Source Type: blogs

Burnout and compassion fatigue: chronic workplace stress and emotional withdrawal
Over the past five years, the term “burnout” has become closely associated with the health care field. It has reached the point where more than 60 percent of surveyed physicians reported experiencing burnout in 2021, indicating that it has become an epidemic within our profession. It’s important to understand that burnout is not a personal Read more… Burnout and compassion fatigue: chronic workplace stress and emotional withdrawal originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 29, 2023 Category: General Medicine Authors: Tags: Physician Cardiology Psychiatry Source Type: blogs

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Is Alzheimer's Disease Primarily a Result of Infection-Driven Inflammation?
Many diseases of aging are strongly associated with chronic inflammation, and inflammatory signaling is involved in disease pathology. Unresolved low-grade inflammatory signaling and excessive immune system activation increases with advancing age, producing the state of immune dysfunction known as inflammaging. Many different factors contribute to this chronic inflammation of aging. They include the presence of lingering senescent cells that actively produce inflammatory secretions, as well as mitochondrial dysfunction resulting in mislocated mitochondrial DNA fragments that can cause an innate inflammatory response. It is...
Source: Fight Aging! - June 22, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A physician ’ s journey through propaganda and misinformation [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join us for a fascinating podcast episode as we explore the dangerous consequences of propaganda and misinformation within the context of the opioid epidemic. Our guest, Jay K. Joshi, a family physician and author of Burden of Pain: A Physician’s Journey through the Opioid Read more… A physician’s journey through propaganda and misinformation [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 20, 2023 Category: General Medicine Authors: Tags: Podcast Pain Management Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechan...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Notes from the 2023 Age-Related Disease Therapeutics Summit
The former Longevity Therapeutics conference series was renamed to the Age-Related Disease Therapeutics Summit and held its fifth event recently in San Francisco. It was a smaller meeting than in past years, perhaps a result of the recent downturn in the global financial and investment environment. Few investors were present. Nonetheless, one can usually learn something interesting from the presenting biotech founders and executives. I took a few notes while I was there to present on progress at Repair Biotechnologies, and they follow in the order of the conference program. Birget Schilling from the Buck Institute f...
Source: Fight Aging! - June 16, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Breaking barriers in Medicaid access [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join us in this insightful podcast episode as we discuss the challenges and importance of Medicaid access in the United States. Our guests include Fatima Al-Shimari, an epidemiologist, and medical students Miriam Al-Saedy and Salsabeal Al-Saedy. We delve into the limited availability of Medicaid Read more… Breaking barriers in Medicaid access [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 16, 2023 Category: General Medicine Authors: Tags: Podcast Public Health & Policy Source Type: blogs

Evidence of Causality in the Relationship Between Excess Body Weight and Accelerated Progression of Aging
In conclusion, this study provides evidence of the causality between overweight and accelerated aging (telomere length decreased, frailty index increased, facial aging increased) and lower life expectancy. Accordingly, the potential significance of weight control and treatment of overweight status in combating accelerated aging need to be emphasized. Link: https://doi.org/10.1111/acel.13899 (Source: Fight Aging!)
Source: Fight Aging! - June 15, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The alarming epidemic of physician burnout and how we can combat it
Physician burnout is not a new issue, but it has become increasingly prevalent in recent years. According to the Medscape’s 2023 survey, 53 percent of physicians say they are burned out, compared to 42 percent in 2018. Burnout among doctors can have disastrous consequences for individuals and society at large. Burnout can lead to reduced Read more… The alarming epidemic of physician burnout and how we can combat it originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 8, 2023 Category: General Medicine Authors: Tags: Physician Psychiatry Source Type: blogs

Unmasking the truth: the shocking reality of the opioid epidemic and who ’ s really to blame
An excerpt from Burden of Pain: A Physician’s Journey through the Opioid Epidemic. Glide your hand over a piece of velvet and you notice the smoothness. You feel its aggregated smoothness, not the individualized roughness of each fiber. Each fleeting fiber, a prick of truth, is nullified, synthesized, and then magnified into the silky fluency Read more… Unmasking the truth: the shocking reality of the opioid epidemic and who’s really to blame originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 7, 2023 Category: General Medicine Authors: Tags: Physician Pain Management Source Type: blogs

A Hand Up, Not a Hand-Out
BY KIM BELLARD As many of you did, I followed the recent debt ceiling saga closely, and am relieved that we now have a compromise, of sorts.  The House Republicans demanded a lot of things, most of which they did not get, but one area where they did prevail was in toughening work requirements for food (SNAP) and income (TANF).  They somehow believe that there are uncounted numbers of “able-bodied” people sitting around on their couches collecting government benefits, a myth that goes back to Ronald Reagan’s welfare queen stereotype, and have long advocated work requirements as the remedy.  Ironic...
Source: The Health Care Blog - June 6, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Guaranteed Income Programs Kim Bellard SNAP Source Type: blogs

Amid an Epidemic of Loneliness, Nonprofits Are Helping Keep Veterans Connected
Many nonprofit organizations in the United States seek to support veterans and foster social connection. The connections and sense of community these programs are building can help to combat the loneliness epidemic that is affecting veterans and non-veterans alike. (Source: The RAND Blog)
Source: The RAND Blog - June 5, 2023 Category: Health Management Authors: Laura Werber Source Type: blogs

Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred yea...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Long Term Hypoxia Slows Aging in an Accelerated Aging Mouse Model
Researchers here show that a mouse model of accelerated aging lives considerably longer when in a low-oxygen atmosphere for most of its life span. This is quite interesting, even given that large effect sizes in accelerated aging models should be taken with a grain of salt. It is most likely that any effect on normal mice would be smaller, and also likely that any form of life extension achieved through manipulation of stress responses, such as the response to hypoxia, will produce much smaller effects in long-lived mammals than in short-lived mammals. As is always the case, recall that when we say "accelerated agin...
Source: Fight Aging! - June 2, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs