A Population Study Correlates Air Pollution with Faster Cognitive Aging
A number of large epidemiological studies provide evidence for long-term exposure to greater levels of air pollution to accelerate the onset and progression of age-related disease. A few of these manage to control for the tendency for wealthier people to avoid living in areas with higher particulate air pollution, and the correlation with worse health remains. Mechanistically, it is thought that particulates provoke greater chronic inflammation via their interaction with lung and other tissues, and this in turn contributes to the cell and tissue dysfunction that leads to age-related disease.
The present study asse...
Source: Fight Aging! - April 17, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Supported self-management – what are we managing, actually?
One of the words that has been in my vocabulary for decades is ‘management.’ No, I don’t mean the proliferative middle management layer infesting healthcare for about as long as I’ve been working in health. I mean ‘pain management’ or ‘supported self-management.’ As ever, what pops up for me is about what, exactly, is being managed?
Is it pain? Well – not exactly. After all, pain does what it does, and if we focus on pain reduction alone just look where that gets us (Ballantyne & Sullivan, 2015; Cutler & Glaeser, 2021). And quickly, lest anyone think I’...
Source: HealthSkills Weblog - April 14, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Uncategorized Source Type: blogs
Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls.
Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A View of Type 2 Diabetes as Accelerated Aging
The mortality characteristics resulting from type 2 diabetes look very much like an accelerated form of normal aging, as noted in today's open access paper reporting on a large epidemiological study. This mortality characteristic is so much like aging that at times in the past researchers have used animal models of type 2 diabetes as stand-ins for aging, in order to conduct studies more rapidly. Type 2 diabetes is a metabolic disease, a condition that usually arises from excess fat tissue, and is characterized by chronic inflammation, excessive blood sugar, high levels of circulating advanced glycation end-products, and ot...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Chronic Pain Accelerates Brain Aging, Perhaps via Inflammation
A range of conditions produce chronic pain in muscle and skeletal tissue. While conditions such as osteoathritis are comparatively well understood, the etiology of chronic muscular pain disorders such as myofascial pain syndrome is poorly understood and treatment options are consequently limited. Here, researchers analyze available epidemiological data on knee osteoarthritis, and show that it suggests an inflammatory link between chronic pain and an accelerated pace of degenerative brain aging.
Individuals suffering from chronic musculoskeletal pain (CMP) may face a higher high risk of brain aging. CMP is a leadin...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Scale And Severity Of The Autism Epidemic Seems To Have Gone Unnoticed By Many.
(Source: Australian Health Information Technology)
Source: Australian Health Information Technology - April 1, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes.
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A Skeptical View of the Role of Nuclear DNA Damage in Aging
https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/
It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
AusHealthIT Poll Number 740 – Results – 31 March, 2024.
Here are the results of the recent
poll.
Is Australia Doing Enough To Manage The Rising Epidemic Of Obesity?
Yes (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - March 31, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
One Habit That Can Fight The “ Hidden Epidemic ” Of Loneliness (M)
Feeling isolated? This simple activity could boost your mental well-being. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 29, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Exercise Loneliness subscribers-only Source Type: blogs
The Long and Tortured History of Alpha-Synuclein and Parkinson ’s Disease
This study tracks the decades-long journey to harness alpha-synuclein as a treatment for Parkinson’s disease. Steven Zecola an activist who tracks Parkinson’s research and was on THCB last month discussing it, offers three key changes needed to overcome the underlying challenges.
A Quick Start for Alpha-Synuclein R&D
In the mid-1990’s, Parkinson’s patient advocacy groups had become impatient by the absence of any major therapeutic advances in the 25 years since L-dopa had been approved for Parkinson’s disease (PD).
The Director of National Institute of Neurological Disorders and Stroke (NINDS) se...
Source: The Health Care Blog - March 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Parkinson's Disease Steven Zecola Source Type: blogs
Interesting Epidemiological Results for Time Restricted Feeding
In this study, researchers investigated the potential long-term health impact of following an 8-hour time-restricted eating plan. They reviewed information about dietary patterns for participants in the annual 2003-2018 National Health and Nutrition Examination Surveys (NHANES) in comparison to data about people who died in the U.S., from 2003 through December 2019, from the Centers for Disease Control and Prevention's National Death Index database.
The analysis found: (a) people who followed a pattern of eating all of their food across less than 8 hours per day had a 91% higher risk of death due to cardiovascular d...
Source: Fight Aging! - March 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
AusHealthIT Poll Number 739 – Results – 24 March, 2024.
Here are the results of the recent
poll.
Does The Government Have Any Sensible Idea On What To Do To Manage And
Reduce The Vaping Epidemic?
Yes & (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - March 24, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
This Psychological Epidemic Is Killing Millions Worldwide
One-third of people over 45 have this chronic psychological problem -- as do many who are younger. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 21, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Depression Source Type: blogs
Microplastics, Major Problem
By KIM BELLARD
It’s been almost four years since I first wrote about microplastics; long story short, they’re everywhere. In the ground, in the oceans (even at the very bottom), in the atmosphere. More to the point, they’re in the air you breathe and in the food you eat. They’re in you, and no one thinks that is a good thing. But we’re only starting to understand the harm they cause.
The Washington Post recently reported:
Scientists have found microplastics — or their tinier cousins, nanoplastics — embedded in the human placenta, in blood, in the heart and in the liver and bowels. In one re...
Source: The Health Care Blog - March 19, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech Kim Bellard Microplastics Source Type: blogs
Wound Care Education for Medical Doctors: Filling the Gap
Whenever I ask a group of doctors, “How many of you have had any training in care and treatment of chronic wounds?” it is the rare person who raises their hand. Despite the urgent need for medical doctors to know how to assess and treat pressure injuries and chronic wounds, there is no formal medical or surgical specialty in wound care. This has resulted in a gap in education, training, and research, with extensive variation in clinical practice. The medical education establishment has simply not caught up to the realities of care for the chronically ill patient. Filling the education gap in wound care is one of my pro...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - March 18, 2024 Category: Geriatrics Authors: Jeffrey M Levine Tags: An Aging World Geriatric Medicine Long-Term Care Pressure Injuries & Wound Care Risk Management aging skin bedsore bedsores decubiti decubitus ulcer end-of-life care geriatrics Healthcare Quality Improving Medical Care Jeff Lev Source Type: blogs
