One Habit That Can Fight The “ Hidden Epidemic ” Of Loneliness (M)
Feeling isolated? This simple activity could boost your mental well-being. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 29, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Exercise Loneliness subscribers-only Source Type: blogs

The Long and Tortured History of Alpha-Synuclein and Parkinson ’s Disease
This study tracks the decades-long journey to harness alpha-synuclein as a treatment for Parkinson’s disease. Steven Zecola an activist who tracks Parkinson’s research and was on THCB last month discussing it, offers three key changes needed to overcome the underlying challenges. A Quick Start for Alpha-Synuclein R&D In the mid-1990’s, Parkinson’s patient advocacy groups had become impatient by the absence of any major therapeutic advances in the 25 years since L-dopa had been approved for Parkinson’s disease (PD). The Director of National Institute of Neurological Disorders and Stroke (NINDS) se...
Source: The Health Care Blog - March 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Parkinson's Disease Steven Zecola Source Type: blogs

Interesting Epidemiological Results for Time Restricted Feeding
In this study, researchers investigated the potential long-term health impact of following an 8-hour time-restricted eating plan. They reviewed information about dietary patterns for participants in the annual 2003-2018 National Health and Nutrition Examination Surveys (NHANES) in comparison to data about people who died in the U.S., from 2003 through December 2019, from the Centers for Disease Control and Prevention's National Death Index database. The analysis found: (a) people who followed a pattern of eating all of their food across less than 8 hours per day had a 91% higher risk of death due to cardiovascular d...
Source: Fight Aging! - March 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

AusHealthIT Poll Number 739 – Results – 24 March, 2024.
Here are the results of the recent poll. Does The Government Have Any Sensible Idea On What To Do To Manage And Reduce The Vaping Epidemic? Yes                                         & (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - March 24, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

This Psychological Epidemic Is Killing Millions Worldwide
One-third of people over 45 have this chronic psychological problem -- as do many who are younger. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 21, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Depression Source Type: blogs

Microplastics, Major Problem
By KIM BELLARD It’s been almost four years since I first wrote about microplastics; long story short, they’re everywhere. In the ground, in the oceans (even at the very bottom), in the atmosphere. More to the point, they’re in the air you breathe and in the food you eat. They’re in you, and no one thinks that is a good thing. But we’re only starting to understand the harm they cause. The Washington Post recently reported: Scientists have found microplastics — or their tinier cousins, nanoplastics — embedded in the human placenta, in blood, in the heart and in the liver and bowels. In one re...
Source: The Health Care Blog - March 19, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech Kim Bellard Microplastics Source Type: blogs

Wound Care Education for Medical Doctors: Filling the Gap
Whenever I ask a group of doctors, “How many of you have had any training in care and treatment of chronic wounds?” it is the rare person who raises their hand. Despite the urgent need for medical doctors to know how to assess and treat pressure injuries and chronic wounds, there is no formal medical or surgical specialty in wound care. This has resulted in a gap in education, training, and research, with extensive variation in clinical practice. The medical education establishment has simply not caught up to the realities of care for the chronically ill patient. Filling the education gap in wound care is one of my pro...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - March 18, 2024 Category: Geriatrics Authors: Jeffrey M Levine Tags: An Aging World Geriatric Medicine Long-Term Care Pressure Injuries & Wound Care Risk Management aging skin bedsore bedsores decubiti decubitus ulcer end-of-life care geriatrics Healthcare Quality Improving Medical Care Jeff Lev Source Type: blogs

Towards a Better Understanding of the Role of the Gut Microbiome in Alzheimer's Disease
This article summarizes research presented at the virtual symposium and workshop, "New Approaches for Understanding the Potential Role of Microbes in Alzheimer's Disease." The objective of these events was to review the evidence base and catalyze research to address knowledge gaps in the hypothesis that infections or microbes play some causative role in the development or progression of Alzheimer's disease. Alzheimer's disease is a complex disease; this symposium was rooted in an understanding that its pathogenesis could be triggered by both microbe-dependent and microbe-independent pathways and the two are not mutually ex...
Source: Fight Aging! - March 15, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What could we do if GLP-1 weight loss drugs were free? Would our obesity epidemic be solved for good?
By CECI CONNOLY and SAMI INKINEN Unless you have been living under a rock, you likely have heard the names Ozempic, Wegovy or Mounjaro. Or perhaps been humming the jingle. Rarely has a class of drugs (in this case, GLP-1s) achieved such widespread attention in popular culture and the media, which has people clamoring for them in every doctor’s office in the nation. And for good reason. What we know is that the efficacy and safety profile of these medications is substantially better than any weight loss drug in the past, while our obesity epidemic has only ballooned. As organizations committed to sound science and h...
Source: The Health Care Blog - March 13, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy ACHP Ceci Connoly GLP-1s Obesity Sami Inkinen virta Source Type: blogs

The ‘Barbie Speech’ – How Much Has Really Changed For Women in America?
By MIKE MAGEE In our world where up is down, and black is white, there is a left and a right – it’s the middle we appear to be missing. Does it exist, or was it make believe all along? Into this existential despair enters Britt Cagle Grant, the 47-year old Federal Judge of the U.S. Court of Appeals for the Eleventh Circuit. The Stanford Law graduate, blessed by the Federalist Society and Leonard Leo, and former clerk of Hon. Brett Kavanaugh, was nominated by Donald Trump and confirmed by the Senate on July 31, 2018. Now six years later, her words in rejecting DeSantis’s “Stop Woke Act” (otherwise kno...
Source: The Health Care Blog - March 11, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Barbie De Santis feminism Mike Magee Terry Sciaivo Source Type: blogs

The Correlation Between Education and Life Expectancy
It is comparatively easy to find correlations in human epidemiological data, but much harder to determine causation. A web of correlations exist between socioeconomic status, education, intelligence, and life expectancy. We can even draw in environmental factors such as degree of exposure to particulate air pollution, which tends to correlate with the wealth of individuals living in a given area. In the matter of education, the effect size is small but the correlation is robust in large data sets. Why this is the case remains a topic for discussion. To measure the pace of aging, the researchers applied an algorith...
Source: Fight Aging! - March 11, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The humorous essay that predicted today ’ s medical anxiety epidemic
In elementary school, we read an essay named ‘The Man Who Was a Hospital’ by Jerome K. Jerome. This is a humorous essay in which the writer describes his misadventure in a humorous way. He says that once, he was reading a liver pill circular when he suspected that his liver was out of order. Read more… The humorous essay that predicted today’s medical anxiety epidemic originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 10, 2024 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Fight Aging! Newsletter, March 11th 2024
In conclusion, this Mendelian randomization study found that Streptococcus was causally associated with Bioage acceleration. Further randomized controlled trials are needed to investigate its role in the aging process. « Back to Top Considering the Mechanisms of Vascular Calcification https://www.fightaging.org/archives/2024/03/considering-the-mechanisms-of-vascular-calcification/ Harmful calcification of structures in the cardiovascular system proceeds alongside the development of the fatty lesions of atherosclerosis. Both disease processes are accelerated by chronic inflammation, but d...
Source: Fight Aging! - March 10, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Continuing the Debate Over Why Time Spent Sitting Correlates with Mortality
We examined the prospective associations of convolutional neural network hip accelerometer posture-classified total sitting time and mean sitting bout duration with all-cause and cardiovascular disease (CVD) death. Women (n=5,856; 79±7 years old) in the Women's Health Initiative Objective Physical Activity and Cardiovascular Health (OPACH) Study wore the ActiGraph GT3X+ for ~7 days from May 2012 to April 2014 and were followed through February 19, 2022 for all-cause and CVD death. The convolutional neural network hip accelerometer posture algorithm classified total sitting time and mean sitting bout duration fr...
Source: Fight Aging! - March 7, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Heat Stress Produces Lasting Cellular Resilience via Formation of Tetraspanin Webs
In this study, we use a robust thermal stress paradigm in C. elegans to uncover causal mechanisms by which transient stress may exert lasting impacts on organismal resilience and longevity. We show that transient heat exposure at 28°C during late larval development activates the gene tsp-1, which encodes a C. elegans homolog of the evolutionarily conserved tetraspanin protein family. Tetraspanin 1 (TSP-1) proteins form tetraspanin web-like structures and are essential for maintaining membrane permeability, barrier functions, and heat-induced organismal resilience and longevity. Initial induction of tsp-1 by heat requires ...
Source: Fight Aging! - March 6, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs