Role of virtual reality in examining the effect of fear of falling (FOF) on postural stability in individuals without and with Parkinsons disease in Egypt: a mixed-methods feasibility study protocol
This study will assess a range of FOF-related responses, including cognitive factors, neuromuscular response and postural stability.
Methods and analysis
This feasibility study will consist of four phases: the first two phases will include people without PD, while the other two will include people diagnosed with PD. Participants will be assessed for direct and indirect responses to real life, as well as virtual environment walking scenarios that may induce FOF. Data from questionnaires, different neurophysiological assessments, movement and gait parameters, alongside evaluations of usability and acceptability, will be col...
Source: BMJ Open - May 1, 2024 Category: General Medicine Authors: Gomaa, Y. S., Awad, M. I., Emara, T., Elbokl, A., Al-Yahya, E., ElMeligie, M. M. Tags: Open access, Rehabilitation medicine Source Type: research
Drug resistance in breast cancer is based on the mechanism of exocrine non-coding RNA
AbstractBreast cancer (BC) ranks first among female malignant tumors and involves hormonal changes and genetic as well as environmental risk factors. In recent years, with the improvement of medical treatment, a variety of therapeutic approaches for breast cancer have emerged and have strengthened to accommodate molecular diversity. However, the primary way to improve the effective treatment of breast cancer patients is to overcome treatment resistance. Recent studies have provided insights into the mechanisms of resistance to exosome effects in BC. Exosomes are membrane-bound vesicles secreted by both healthy and malignan...
Source: Hormones and Cancer - May 1, 2024 Category: Cancer & Oncology Source Type: research
Dual-step pharmacological intervention for traumatic-like memories: implications from D-cycloserine and cannabidiol or clonidine in male and female rats
ConclusionsThese findings highlight the importance of NMDA receptor signaling in memory destabilization and underscore the efficacy of a dual-step pharmacological intervention in attenuating traumatic-like memories, even in a context different from the original learning environment.Graphical Abstract (Source: Psychopharmacology)
Source: Psychopharmacology - May 1, 2024 Category: Psychiatry Source Type: research
Sensors, Vol. 24, Pages 2897: A Survey on Satellite Communication System Security
n Lee
In recent years, satellite communication systems (SCSs) have rapidly developed in terms of their role and capabilities, promoted by advancements in space launch technologies. However, this rapid development has also led to the emergence of significant security vulnerabilities, demonstrated through real-world targeted attacks such as AcidRain and AcidPour that demand immediate attention from the security community. In response, various countermeasures, encompassing both technological and policy-based approaches, have been proposed to mitigate these threats. However, the multitude and diversity of these proposals m...
Source: Sensors - May 1, 2024 Category: Biotechnology Authors: Minjae Kang Sungbin Park Yeonjoon Lee Tags: Review Source Type: research
Sensors, Vol. 24, Pages 2899: Bat2Web: A Framework for Real-Time Classification of Bat Species Echolocation Signals Using Audio Sensor Data
Dana Dghaym
Bats play a pivotal role in maintaining ecological balance, and studying their behaviors offers vital insights into environmental health and aids in conservation efforts. Determining the presence of various bat species in an environment is essential for many bat studies. Specialized audio sensors can be used to record bat echolocation calls that can then be used to identify bat species. However, the complexity of bat calls presents a significant challenge, necessitating expert analysis and extensive time for accurate interpretation. Recent advances in neural networks can help identify bat species automatica...
Source: Sensors - May 1, 2024 Category: Biotechnology Authors: Taslim Mahbub Azadan Bhagwagar Priyanka Chand Imran Zualkernan Jacky Judas Dana Dghaym Tags: Article Source Type: research
Sensors, Vol. 24, Pages 2900: Soft Sensory-Motor System Based on Ionic Solution for Robotic Applications
This study provides a comparative analysis of the performance of SSMS-IS prototypes with three diverse designs: toroidal, semi-toroidal, and rectangular geometries, based on a series of performance experiments, such as sensitivity, drift, and durability. The design with the best performance was the rectangular SSMS-IS using silicon rubber RPRO20 for both internal and external pressures applied in the system. Moreover, this work explores the performance of a bioinspired soft robot using rectangular SSMS-IS elements integrated in its body. Further, it investigated the feasibility of the robot to adapt its morphology online f...
Source: Sensors - May 1, 2024 Category: Biotechnology Authors: Sender Rocha dos Santos Eric Rohmer Tags: Article Source Type: research
IJERPH, Vol. 21, Pages 582: Evolving Adult ADHD Care: Preparatory Evaluation of a Prototype Digital Service Model Innovation for ADHD Care
Conclusions: A consumer-centred approach to digital health service innovation, featuring streamlined, private, and secure solutions with enhanced mobile tools proves instrumental in bridging gaps in ADHD care in Australia. These innovations should help to address the gaps in ADHD care in Australia. These innovations should encompass integrated care, targeted treatment outcome data, and additional lifestyle support, whilst recognising the tensions between customised functionalities and streamlined displays. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Bronwin Patrickson Lida Shams John Fouyaxis J örg Strobel Klaus Oliver Schubert Mike Musker Niranjan Bidargaddi Tags: Article Source Type: research
IJERPH, Vol. 21, Pages 580: Diagnosis in Bytes: Comparing the Diagnostic Accuracy of Google and ChatGPT 3.5 as an Educational Support Tool
Conclusion: ChatGPT 3.5 demonstrated higher diagnostic accuracy than Google in both contexts. The platform showed satisfactory accuracy when diagnosing common cases, yet its performance in identifying rare conditions remains limited. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Guilherme R. Guimaraes Ricardo G. Figueiredo Caroline Santos Silva Vanessa Arata Jean Carlos Z. Contreras Cristiano M. Gomes Ricardo B. Tiraboschi Jos é Bessa Junior Tags: Article Source Type: research
IJERPH, Vol. 21, Pages 581: Behind the Hospital Ward: In-Hospital Mortality of Type 2 Diabetes Mellitus Patients in Indonesia (Analysis of National Health Insurance Claim Sample Data)
This study examined in-hospital mortality among patients diagnosed with non-insulin-dependent diabetes mellitus (NIDDM) of ICD-10, or Type 2 Diabetes Mellitus (T2DM), in Indonesia, utilizing hospital claims data spanning from 2017 to 2022 obtained from the Indonesia Health Social Security Agency or Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan. The analysis, which included 610,809 hospitalized T2DM patients, revealed an in-hospital mortality rate of 6.6%. Factors contributing to an elevated risk of mortality included advanced age, the presence of comorbidities, and severe complications. Additionally, patients receivi...
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Ede Surya Darmawan Vetty Yulianty Permanasari Latin Vania Nisrina Dian Kusuma Syarif Rahman Hasibuan Nisrina Widyasanti Tags: Article Source Type: research
IJERPH, Vol. 21, Pages 579: Spatio-Temporal Variation in the Exceedance of Enterococci in Lake Burley Griffin: An Analysis of 16 Years & rsquo; Recreational Water Quality Monitoring Data
This study analysed enterococci concentrations from seven recreational sites from 2001–2021 to examine spatial and temporal patterns in exceedances during the swimming season (October–April), when exposure is highest. The enterococci concentrations varied significantly across sites and in the summer months. The frequency of the exceedances was higher in the 2009–2015 period than in the 2001–2005 and 2015–2021 periods. The odds of alert-level concentrations were greater in November, December, and February compared to October. The odds of exceedance were h...
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Ripon Kumar Adhikary Danswell Starrs David Wright Barry Croke Kathryn Glass Aparna Lal Tags: Article Source Type: research
Oracle, Merakai, Appollo, Yang by Claire Roche
Art is integrated into the Mayo Clinic environment. Since the original Mayo Clinic Building was finished in 1914, many pieces have been donated or commissioned for patients and staff to enjoy. Each issue of Mayo Clinic Proceedings features a work of art (as interpreted by the author) that is displayed in a building or on the grounds of Mayo Clinic campuses. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - May 1, 2024 Category: Internal Medicine Authors: Margaret R. Wentz Tags: Art at mayo clinic Source Type: research
Systematic evaluation and meta-analysis of the effects of major dietary patterns on cognitive function in healthy adults
. (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - May 1, 2024 Category: Nutrition Authors: HanQing GuoQi TianXueMei QinQing LuoXiuMei GongQinghan Gaoa School of Public Health, Ningxia Medical University, Yinchuan, People ’s Republic of Chinab Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinc Source Type: research
Studying the relationship between different stages of Parkinson's disease and iron metabolism, oxidative stress, and inflammation from Qinghai-Tibetan Plateau Area
Background: To explore the correlation between different stages of Parkinson's disease (PD)and serum iron metabolism, oxidative stress, and inflammation in hypoxic environments. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: L. Yan, A. Zhu Source Type: research
Study protocol: Exploration of sternal focused vibrotactile stimulation in people with Parkinson's disease experiencing Freezing of Gait
Background: Freezing of Gait (FoG), a symptom of Parkinson ’s Disease (PD), poses significant challenges. Compensatory strategies like cueing and high-frequency vibrotactile stimulation have proven effective in alleviating FoG severity. Understanding functional mobility, defined as a person's ability to move independently and safely across environments, i s vital for task accomplishment. The potential impact of individualized Focused Sternal Vibrotactile Stimulation (FocuS) on functional mobility and FoG in people with PD (PwPD) over a 2-week period remains unexplored. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: A. Wilhelm, T. Miksch, H. K öttl, J. Janssen, P. Augat Source Type: research
Communication in Parkinson ’s Disease and Healthy Controls: A Mixed-Methods Exploration of Conversational Speech Recordings in Natural Environments
Background: Parkinson ’s disease (PD) is characterized by a shortage of the neurotransmitter dopamine which is vital for motor control. PD progression involves motor control for speech production. Qualitative literature on communication of people with Parkinson's Disease (PWPD) primarily involves interviews or question naires with PWPD or their caregivers. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: C. Rountrey, A. Spotts Source Type: research
