Exploring the multifaceted bioactivities of < em > Lavandula pinnata L. < /em > essential oil: promising pharmacological activities
This study investigates the biological activities of Lavandula pinnata essential oil (LPEO), an endemic lavender species from the Canary Islands, traditionally used in treating various ailments. Methods: LPEO was extracted by hydrodistillation and analyzed using GC-MS. Antioxidant activity was assessed by DPPH radical scavenging and total antioxidant capacity assays. Antimicrobial activity was evaluated by disc diffusion, MIC, MBC, and MFC determination against bacterial (Staphylococcus aureus, Micrococcus luteus, Escherichia coli, Pseudomonas aeruginosa) and fungal (Candida glabrata, Rhodotorula glutinis, Aspergillus nige...
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Mounir Haddou Amine Elbouzidi Mohamed Taibi Abdellah Baraich El Hassania Loukili Reda Bellaouchi Ennouaamane Saalaoui Abdeslam Asehraou Ahmad Mohammad Salamatullah Mohammed Bourhia Hiba-Allah Nafidi Mohamed Addi Bouchra El Guerrouj Khalid Chaabane Source Type: research

Tandemly expanded OR17b in Himalaya ghost moth facilitates larval food allocation via olfactory reception of plant-derived tricosane
Int J Biol Macromol. 2024 Apr 23:131503. doi: 10.1016/j.ijbiomac.2024.131503. Online ahead of print.ABSTRACTHerbivorous insects utilize intricate olfactory mechanisms to locate food plants. The chemical communication of insect-plant in primitive lineage offers insights into evolutionary milestones of divergent olfactory modalities. Here, we focus on a system endemic to the Qinghai-Tibetan Plateau to unravel the chemical and molecular basis of food preference in ancestral Lepidoptera. We conducted volatile profiling, neural electrophysiology, and chemotaxis assays with a panel of host plant organs to identify attractants fo...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Rui Tang Hao Guo Jia-Qi Chen Cong Huang Xiang-Xin Kong Li Cao Fang-Hao Wan Ri-Chou Han Source Type: research

Viruses, Vol. 16, Pages 669: Identification of HLA-A*11:01 and A*02:01-Restricted EBV Peptides Using HLA Peptidomics
Xiaofei Zhang Miao Xu Epstein-Barr Virus (EBV) is closely linked to nasopharyngeal carcinoma (NPC), notably prevalent in southern China. Although type II latency of EBV plays a crucial role in the development of NPC, some lytic genes and intermittent reactivation are also critical for viral propagation and tumor progression. Since T cell-mediated immunity is effective in targeted killing of EBV-positive cells, it is important to identify EBV-derived peptides presented by highly prevalent human leukocyte antigen class I (HLA-I) molecules throughout the EBV life cycle. Here, we constructed an EBV-positive NPC cell mo...
Source: Viruses - April 25, 2024 Category: Virology Authors: Yufei Wang Wanlin Zhang Ruona Shi Yanran Luo Zhenhuan Feng Yanhong Chen Qiuting Zhang Yan Zhou Jingtong Liang Xiaoping Ye Qisheng Feng Xiaofei Zhang Miao Xu Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1970: Chemical Characterization of the Essential Oil Compositions of Mentha spicata and M. longifolia ssp. cyprica from the Mediterranean Basin and Multivariate Statistical Analyses
m Yavuz This present study aims to characterize the essential oil compositions of the aerial parts of M. spicata L. and endemic M. longifolia ssp. cyprica (Heinr. Braun) Harley by using GC-FID and GC/MS analyses simultaneously. In addition, it aims to perform multivariate statistical analysis by comparing with the existing literature, emphasizing the literature published within the last two decades, conducted on both species growing within the Mediterranean Basin. The major essential oil components of M. spicata were determined as carvone (67.8%) and limonene (10.6%), while the major compounds of M. longifolia ssp. cyp...
Source: Molecules - April 25, 2024 Category: Chemistry Authors: Hasan İsfendiyaroğlu Azmi Hano ğlu Duygu Yi ğit Hanoğlu Fehmi B. Alka ş Kemal H üsnü Can Başer Dudu Özkum Yavuz Tags: Article Source Type: research

Viruses, Vol. 16, Pages 675: First Report of Endemic Frog Virus 3 (FV3)-like Ranaviruses in the Korean Clawed Salamander (Onychodactylus koreanus) in Asia
esik Park Frog virus 3 (FV3) in the genus Ranavirus of the family Iridoviridae causes mass mortality in both anurans and urodeles worldwide; however, the phylogenetic origin of FV3-like ranaviruses is not well established. In Asia, three FV3-like ranaviruses have been reported in farmed populations of amphibians and reptiles. Here, we report the first case of endemic FV3-like ranavirus infections in the Korean clawed salamander Onychodactylus koreanus, caught in wild mountain streams in the Republic of Korea (ROK), through whole-genome sequencing and phylogenetic analysis. Two isolated FV3-like ranaviruses (Onychodacty...
Source: Viruses - April 25, 2024 Category: Virology Authors: Jongsun Kim Haan Woo Sung Tae Sung Jung Jaejin Park Daesik Park Tags: Article Source Type: research

Unravelling < i > Chlamydia trachomatis < /i > diversity in Amhara, Ethiopia: MLVA- < i > ompA < /i > sequencing as a molecular typing tool for trachoma
by Anna J. Harte, Ehsan Ghasemian, Harry Pickering, Joanna Houghton, Ambahun Chernet, Eshetu Sata, Gizachew Yismaw, Taye Zeru, Zerihun Tadesse, E. Kelly Callahan, Scott D. Nash, Martin Holland Trachoma is the leading infectious cause of blindness worldwide and is now largely confined to around 40 low- and middle-income countries. It is caused byChlamydia trachomatis (Ct), a contagious intracellular bacterium. The World Health Organization recommends mass drug administration (MDA) with azithromycin for treatment and control of ocular Ct infections, alongside improving facial cleanliness and environmental conditions to redu...
Source: PLoS Neglected Tropical Diseases - April 25, 2024 Category: Tropical Medicine Authors: Anna J. Harte Source Type: research

Echocardiographic Screening for Rheumatic Heart Disease: A Brief History and Implications for the Future
Transthoracic echocardiography is the gold standard for early detection of rheumatic heart disease (RHD) in asymptomatic children living in high-risk regions. Advances in technology allowing miniaturisation and increased portability of echocardiography devices have improved the accessibility of this vital diagnostic tool in RHD-endemic locations. Automation of image optimisation techniques and simplified RHD screening protocols permit use by non-experts after a brief period of training. While these changes are welcome advances in the battle to manage RHD, it is important that the sensitivity and specificity of RHD detectio...
Source: Heart, Lung and Circulation - April 25, 2024 Category: Cardiology Authors: Jacqueline Williamson, Bo Remenyi, Joshua Francis, Peter Morris, Gillian Whalley Tags: Review Source Type: research

Patients hospitalized with active tuberculosis and Covid-19 coinfection: A matched case-control from the Brazilian Covid-19 Registry
An Acad Bras Cienc. 2024 Apr 22;96(1):e20230791. doi: 10.1590/0001-3765202420230791. eCollection 2024.ABSTRACTAlthough control of Covid-19 has improved, the virus continues to cause infections, such as tuberculosis, that is still endemic in many countries, representing a scenario of coinfection. To compare Covid-19 clinical manifestations and outcomes between patients with active tuberculosis infection and matched controls. This is a matched case-control study based on data from the Brazilian Covid-19 Registry, in hospitalized patients aged 18 or over with laboratory confirmed Covid-19 from March 1, 2020, to March 31, 2022...
Source: An Acad Bras Cienc - April 24, 2024 Category: Science Authors: Rafael L R Carvalho Gabriella G Aguiar Jessica F B Moreira Daniella N Pereira Val éria Maria Augusto Alexandre V Schwarzbold Carolina C Matos Danyelle R A Rios Fel ício R Costa Fernando Anschau Jos é Miguel Chatkin Karen B Ruschel Marcelo Carneiro Neim Source Type: research

Malaria in a vulnerable population living in quilombo remnant communities in the Brazilian Amazon: a cross-sectional study from 2005-2020
Rev Inst Med Trop Sao Paulo. 2024 Apr 19;66:e25. doi: 10.1590/S1678-9946202466025. eCollection 2024.ABSTRACTQuilombo remnant communities are areas officially recognized by the Brazilian government as historical communities founded by formerly enslaved individuals. These communities are mostly located in the endemic areas of malaria in the Brazilian Amazon. We retrospectively described the prevalence of malaria among individuals living in 32 recognized quilombo remnant communities in the Baiao and Oriximina municipalities located in the Para State. The number of malaria cases and the Annual Parasitic Incidence (API) recorde...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - April 24, 2024 Category: Tropical Medicine Authors: Beatriz Costa Ribeiro Carla Gisele R Garcia Lilian J éssica Passos Lima Jo ão F Guerreiro Marinete Marins P óvoa Maristela G Cunha Source Type: research

A Troublesome Complication of Hydatid Cysts; Intra-Abdominal Rupture: A 10-Year Study from a High-Volume Center
CONCLUSION: Hydatid cyst rupture should be considered in cases of acute abdomen, particularly in regions where the disease is endemic, as in our region. The ruptured hydatid cyst was primarily observed in the liver (94.11% of cases).PMID:38654950 | PMC:PMC11033535 | DOI:10.18502/ijpa.v19i1.15199 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: H üseyin Yönder Mehmet Sait Berhuni Hasan Elkan Abdullah Özgönül Ahmet Bertan Vedat Kaplan Ali Uzunk öy Source Type: research

A 4-Year-Old Child with a Giant Cerebral Hydatid Cyst: A Case Report
Iran J Parasitol. 2024 Jan-Mar;19(1):113-116. doi: 10.18502/ijpa.v19i1.15218.ABSTRACTEchinococcosis is the most common cestode infection globally caused by the Echinococcus species. The most common organ involvement is the lungs and liver, but other organs can be rarely involved. Here, we present a case with a giant cerebral hydatid cyst. A 4-year-old boy presented with abnormal gait and walking at Marmara University School of Medicine Pendik Training and Research Hospital, Istanbul, Türkiye in September 2022. Cranial magnetic resonance imaging showed a cyst of 13 cm in diameter. The cyst was enucleated successfully with ...
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Aylin Dizi I şık Özcan Sönmez P ınar Canizci Erdemli Eda Kepenekli Zeynep Ergen ç Seyhan Y ılmaz Sevgi Aslan Tuncay Burcu Parlak Adnan Da ğçınar Source Type: research

An Unusual Cause of Insidious Back and Shoulder Pain in a Man: A Case Report
In this study, we aimed to raise awareness by presenting the first reported isolated hydatid cyst in the infraspinatus muscle case from our country, which is extremely rare.PMID:38654945 | PMC:PMC11033544 | DOI:10.18502/ijpa.v19i1.15220 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: O ğuz Kaya Nevzat G önder Source Type: research

Visceral Leishmaniasis (VL) Clinical Presentation, Laboratory Findings, Treatment Options and Outcome
CONCLUSION: VL should be included in the differential diagnosis of any child who presents with fever, splenomegaly, and anemia. Concerning the treatment strategy in this study, liposomal amphotericin B had more efficiency and shorter hospitalization duration.PMID:38654944 | PMC:PMC11033536 | DOI:10.18502/ijpa.v19i1.15190 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Mahmoud Khodabandeh Elham Moradian Maedeh Sarvari Mahsa Soti Khiabani Source Type: research

COVID-19 Vaccination-Related Myocarditis: What We Learned From Our Experience and What We Need to Do in The Future
Korean Circ J. 2024 Apr 1. doi: 10.4070/kcj.2024.0065. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has led to a global health crisis with substantial mortality and morbidity. To combat the COVID-19 pandemic, various vaccines have been developed, but unexpected serious adverse events including vaccine-induced thrombotic thrombocytopenia, carditis, and thromboembolic events have been reported and became a huddle for COVID-19 vaccination. Vaccine-related myocarditis (VRM) is a rare but significant adverse event associated primarily with mRNA vacci...
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Jae-Hyeong Park Kye Hun Kim Source Type: research

Patients hospitalized with active tuberculosis and Covid-19 coinfection: A matched case-control from the Brazilian Covid-19 Registry
An Acad Bras Cienc. 2024 Apr 22;96(1):e20230791. doi: 10.1590/0001-3765202420230791. eCollection 2024.ABSTRACTAlthough control of Covid-19 has improved, the virus continues to cause infections, such as tuberculosis, that is still endemic in many countries, representing a scenario of coinfection. To compare Covid-19 clinical manifestations and outcomes between patients with active tuberculosis infection and matched controls. This is a matched case-control study based on data from the Brazilian Covid-19 Registry, in hospitalized patients aged 18 or over with laboratory confirmed Covid-19 from March 1, 2020, to March 31, 2022...
Source: An Acad Bras Cienc - April 24, 2024 Category: Science Authors: Rafael L R Carvalho Gabriella G Aguiar Jessica F B Moreira Daniella N Pereira Val éria Maria Augusto Alexandre V Schwarzbold Carolina C Matos Danyelle R A Rios Fel ício R Costa Fernando Anschau Jos é Miguel Chatkin Karen B Ruschel Marcelo Carneiro Neim Source Type: research