Longitudinal Multimodal Transformer Integrating Imaging and Latent Clinical Signatures From Routine EHRs for Pulmonary Nodule Classification
Med Image Comput Comput Assist Interv. 2023 Oct;14221:649-659. doi: 10.1007/978-3-031-43895-0_61. Epub 2023 Oct 1.ABSTRACTThe accuracy of predictive models for solitary pulmonary nodule (SPN) diagnosis can be greatly increased by incorporating repeat imaging and medical context, such as electronic health records (EHRs). However, clinically routine modalities such as imaging and diagnostic codes can be asynchronous and irregularly sampled over different time scales which are obstacles to longitudinal multimodal learning. In this work, we propose a transformer-based multimodal strategy to integrate repeat imaging with longit...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - May 23, 2024 Category: Radiology Authors: Thomas Z Li John M Still Kaiwen Xu Ho Hin Lee Leon Y Cai Aravind R Krishnan Riqiang Gao Mirza S Khan Sanja Antic Michael Kammer Kim L Sandler Fabien Maldonado Bennett A Landman Thomas A Lasko Source Type: research

Abnormal Electroencephalogram Findings and Its Correlation With Clinical Features From Pediatric Patients in Psychiatric Clinic
Conclusion: EEG abnormalities were common in pediatric patients with psychiatric disorders, with background abnormalities detected as frequently as IEDs. Disease severity was not associated with EEG abnormality, while IQ scores showed a negative correlation.PMID:38778758 | DOI:10.1177/15500594241256170 (Source: Clinical EEG and Neuroscience)
Source: Clinical EEG and Neuroscience - May 23, 2024 Category: Neuroscience Authors: Young Jun Ko Jae Hyun Han Anna Cho Heejeong Yoo Hunmin Kim Source Type: research

How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC
Heart failure (HF) care to promote implementation of HF with reduced ejection fraction (HFrEF) guideline-directed medical therapy (GDMT). EHR, electronic health record; EP, electrophysiologist; GP, general practitioner; OMT, optimal medical therapy; PIP, potentially inappropriate prescription; WHF, worsening heart failure. AbstractGuideline-directed medical therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF) reduces morbidity and mortality, but its implementation is often poor in daily clinical practice. Barriers to implementation include clinical and organizational factors that might contri...
Source: European Journal of Heart Failure - May 23, 2024 Category: Cardiology Authors: Gianluigi Savarese, Felix Lindberg, Antonio Cannata, Ovidiu Chioncel, Davide Stolfo, Francesca Musella, Daniela Tomasoni, Magdy Abdelhamid, Debasish Banerjee, Antoni Bayes ‐Genis, Emmanuelle Berthelot, Frieder Braunschweig, Andrew J.S. Coats Tags: Position Paper Source Type: research

Prevalence, incidence, mortality, and healthcare resource use for generalised pustular psoriasis, palmoplantar pustulosis, and plaque psoriasis in England: a population-based cohort study
CONCLUSIONS: Our results provide further evidence that GPP is a distinct disease with different epidemiology, lower survival and higher HCRU than plaque psoriasis in England.PMID:38775029 | DOI:10.1093/bjd/ljae217 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 22, 2024 Category: Dermatology Authors: Monika Frysz Smit Patel Marie Oy Yee Li Christopher E M Griffiths Richard B Warren Darren M Ashcroft Source Type: research

Cardiovascular and Noncardiovascular Prescribing and Mortality After Takotsubo Comparison With Myocardial Infarction and General Population
CONCLUSIONS: In patients with takotsubo syndrome, cardiovascular mortality is the leading cause of death, and this is not associated with cardiovascular therapy use.PMID:38774915 | PMC:PMC7615966 | DOI:10.1016/j.jacadv.2023.100797 (Source: Adv Data)
Source: Adv Data - May 22, 2024 Category: Epidemiology Authors: Amelia E Rudd Graham Horgan Hilal Khan David T Gamble Jim McGowan Arvind Sood Ross McGeoch John Irving Jonathan Watt Stephen J Leslie Mark Petrie Chim Lang Nicholas L Mills David E Newby Dana K Dawson Source Type: research

Unhealthy Alcohol Use among Adults with Depression or Anxiety: Changes During COVID-19 and Associations with Mental Health Treatment
CONCLUSIONS: Contrary to expectations, patients with unhealthy alcohol use and depression or anxiety decreased alcohol use more than those without depression or anxiety during COVID-19, whether or not they accessed mental health services.PMID:38775320 | DOI:10.15288/jsad.23-00373 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - May 22, 2024 Category: Addiction Authors: Derek D Satre Vanessa A Palzes Felicia W Chi Andrea H Kline-Simon Cynthia I Campbell Natalia Van Doren Constance Weisner Stacy Sterling Source Type: research

Prevalence, incidence, mortality, and healthcare resource use for generalised pustular psoriasis, palmoplantar pustulosis, and plaque psoriasis in England: a population-based cohort study
CONCLUSIONS: Our results provide further evidence that GPP is a distinct disease with different epidemiology, lower survival and higher HCRU than plaque psoriasis in England.PMID:38775029 | DOI:10.1093/bjd/ljae217 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 22, 2024 Category: Dermatology Authors: Monika Frysz Smit Patel Marie Oy Yee Li Christopher E M Griffiths Richard B Warren Darren M Ashcroft Source Type: research

Use of Natural Language Understanding to Facilitate Surgical De-Escalation of Axillary Staging in Patients With Breast Cancer
CONCLUSION: Data from our NLU model suggest that omission of sentinel lymph node biopsy might be extended beyond Choosing Wisely recommendations, limited to those older than 70 years and to all postmenopausal women with early-stage ER+/cN0 disease. These data support the recently reported SOUND trial results and provide additional granularity to facilitate surgical de-escalation.PMID:38776506 | DOI:10.1200/CCI.23.00177 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - May 22, 2024 Category: Cancer & Oncology Authors: Neil Carleton Gilan Saadawi Priscilla F McAuliffe Atilla Soran Steffi Oesterreich Adrian V Lee Emilia J Diego Source Type: research

Use of Natural Language Understanding to Facilitate Surgical De-Escalation of Axillary Staging in Patients With Breast Cancer
CONCLUSION: Data from our NLU model suggest that omission of sentinel lymph node biopsy might be extended beyond Choosing Wisely recommendations, limited to those older than 70 years and to all postmenopausal women with early-stage ER+/cN0 disease. These data support the recently reported SOUND trial results and provide additional granularity to facilitate surgical de-escalation.PMID:38776506 | DOI:10.1200/CCI.23.00177 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - May 22, 2024 Category: Cancer & Oncology Authors: Neil Carleton Gilan Saadawi Priscilla F McAuliffe Atilla Soran Steffi Oesterreich Adrian V Lee Emilia J Diego Source Type: research

Cardiovascular and Noncardiovascular Prescribing and Mortality After Takotsubo Comparison With Myocardial Infarction and General Population
CONCLUSIONS: In patients with takotsubo syndrome, cardiovascular mortality is the leading cause of death, and this is not associated with cardiovascular therapy use.PMID:38774915 | PMC:PMC7615966 | DOI:10.1016/j.jacadv.2023.100797 (Source: Adv Data)
Source: Adv Data - May 22, 2024 Category: Epidemiology Authors: Amelia E Rudd Graham Horgan Hilal Khan David T Gamble Jim McGowan Arvind Sood Ross McGeoch John Irving Jonathan Watt Stephen J Leslie Mark Petrie Chim Lang Nicholas L Mills David E Newby Dana K Dawson Source Type: research

Unhealthy Alcohol Use among Adults with Depression or Anxiety: Changes During COVID-19 and Associations with Mental Health Treatment
CONCLUSIONS: Contrary to expectations, patients with unhealthy alcohol use and depression or anxiety decreased alcohol use more than those without depression or anxiety during COVID-19, whether or not they accessed mental health services.PMID:38775320 | DOI:10.15288/jsad.23-00373 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - May 22, 2024 Category: Addiction Authors: Derek D Satre Vanessa A Palzes Felicia W Chi Andrea H Kline-Simon Cynthia I Campbell Natalia Van Doren Constance Weisner Stacy Sterling Source Type: research

Acute and long-term outcomes of SARS-CoV-2 infection in school-aged children in England: Study protocol for the joint analysis of the COVID-19 schools infection survey (SIS) and the COVID-19 mapping and mitigation in schools (CoMMinS) study
ConclusionLinked SIS-1 and CoMMinS data represent a unique and rich resource for understanding the impact of SARS-CoV-2 infection on children ’s health, benefiting from enhanced SARS-CoV-2 testing and ability to assess a wide range of outcomes. (Source: PLoS One)
Source: PLoS One - May 22, 2024 Category: Biomedical Science Authors: Katharine J. Looker Source Type: research