Usefulness of nabilone as an antiemetic in persistent vomiting due to refractory gastrointestinal disorders
Rev Esp Enferm Dig. 2023 Jun 14. doi: 10.17235/reed.2023.9719/2023. Online ahead of print.ABSTRACTNabilone, a synthetic analogue of delta-9-Tetrahydrocannabinol, is an agonist of cannabinoid receptors (CB-1 and CB-2) approved to treat chemotherapy-induced vomiting refractory to antiemetics. Its use in patients with refractory vomiting due to gastrointestinal dysmotility (GID) has not been reported. Our study aims are to assess nabilone usefulness and side-effects in patients with refractory vomiting due to GID. Patients prescribed nabilone at St. Mark's intestinal rehabilitation unit (January 2017 to September 2022) due to...
Source: Revista Espanola de Enfermedades Digestivas - June 14, 2023 Category: Gastroenterology Authors: Cristina Olmedo Moreno Richard Holman Manni Naghibi Suzanne Donnelly Alison Culkin Lilia Malcom Nicola Vernon Simon Gabe Source Type: research
Evaluation of Esophageal Dysphagia in Elderly Patients
AbstractPurpose of ReviewWhile guidelines exist for the evaluation and management of esophageal dysphagia in the general population, dysphagia disproportionately affects the elderly. In this article, we reviewed the literature on evaluating esophageal dysphagia in elderly patients and proposed a diagnostic algorithm based on this evidence.Recent FindingsIn older patients, dysphagia is often well compensated for by altered eating habits and physiologic changes, underreported by patients, and missed by healthcare providers. Once identified, dysphagia should be differentiated into oropharyngeal and esophageal dysphagia to gui...
Source: Current Gastroenterology Reports - June 14, 2023 Category: Gastroenterology Source Type: research
Safety and efficacy of esoflip dilation in patients with esophageal dysmotility: a systematic review meta-analysis
Geisinger Medical Center, USA; University of Toledo - Health Science Campus, USA; Capital Health Regional Medical Center, USA; Dow University of Health Sciences, Pakistan. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 1, 2023 Category: Gastroenterology Authors: Umair Iqbal, Zohaib Ahmed, Hafsa Anwar, Syeda Faiza Arif, Wade Lee-Smith, Abdallah Kobeissy, Toseef Javaid, David Diehl Tags: Esophagus 1 Sunday, May 7, 2023 12:30 PM - 1:30 PM Source Type: research
Characterizing esophageal dysmotility by flip planimetry and high-resolution manometery in post-obesity surgery patients
Mayo Clinic Minnesota, USA. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 1, 2023 Category: Gastroenterology Authors: Mark Hanscom, Farah Abdul Razzak, Donna Maria Abboud, Karim Al Annan, Anthony Kerbage, Rudy Mrad, Vitor Brunaldi, Andrew Storm, Eric Vargas, Omar Ghanem, Karthik Ravi, Barham Abu Dayyeh Tags: Bariatric Endoscopy Saturday, May 6, 2023 12:30 PM - 1:30 PM Source Type: research
A PhysioMechanical model of esophageal function in eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is characterized by eosinophilic inflammation, but also heterogeneous presentations involving fibrostenotic esophageal remodeling and esophageal dysmotility. We aimed to define and evaluate phenotypes of EoE using functional lumen imaging probe (FLIP) Panometry, i.e. a PhysioMechanical Classification of EoE. (Source: Gastroenterology)
Source: Gastroenterology - May 29, 2023 Category: Gastroenterology Authors: D.A. Carlson, I. Hirano, N. Gonsalves, P.J. Kahrilas, I.K. Araujo, M. Yang, M.P. Tetreault, J.E. Pandolfino Tags: Clinical - Alimentary Tract Source Type: research
GSE229322 The enteric nervous system relays psychological stress to intestinal inflammation [SnRNASeq_ENS]
Contributor : Christoph A ThaissSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMental health profoundly impacts inflammatory responses in the body. This is particularly apparent in inflammatory bowel disease (IBD), where psychological stress is associated with disease flares. Here, we discover a critical role for the enteric nervous system (ENS) in mediating the aggravating effect of chronic stress on intestinal inflammation. We find that chronically elevated levels of glucocorticoids drive the generation of an inflammatory subset of enteric glia that promotes monocyte- and TNF-media...
Source: GEO: Gene Expression Omnibus - May 25, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE229321 The enteric nervous system relays psychological stress to intestinal inflammation [ScRNASeqCD45seq]
Contributor : Christoph A ThaissSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMental health profoundly impacts inflammatory responses in the body. This is particularly apparent in inflammatory bowel disease (IBD), where psychological stress is associated with disease flares. Here, we discover a critical role for the enteric nervous system (ENS) in mediating the aggravating effect of chronic stress on intestinal inflammation. We find that chronically elevated levels of glucocorticoids drive the generation of an inflammatory subset of enteric glia that promotes monocyte- and TNF-media...
Source: GEO: Gene Expression Omnibus - May 25, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
