Acute exposure of Isopyrazam damages the developed cardiovascular system of zebrafish (Danio rerio)
J Environ Sci Health B. 2023 Apr 9:1-11. doi: 10.1080/03601234.2023.2197655. Online ahead of print.ABSTRACTIsopyrazam (IPZ) is one of the broad-spectrum succinate dehydrogenase inhibitor fungicides (SDHIs). Although the potential bio-toxicity of SDHIs has been reported hourly, the specific effects focused on the cardiovascular system have remained unclear and piecemeal. Thus, we chose IPZ as a representative to observe the cardiovascular toxicity of SDHIs in zebrafish. Two types of transgenic zebrafish, Tg (cmlc2:GFP) and Tg (flk1:GFP) were used in this study. Healthy embryos at 6 hpf were exposed to IPZ solutions. The sta...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 10, 2023 Category: Environmental Health Authors: Yuepei Yan Shuang Liang Tao Zhang Chengchen Deng Huili Li Dechuan Zhang Daoxi Lei Guixue Wang Source Type: research

Acute exposure of Isopyrazam damages the developed cardiovascular system of zebrafish (Danio rerio)
J Environ Sci Health B. 2023 Apr 9:1-11. doi: 10.1080/03601234.2023.2197655. Online ahead of print.ABSTRACTIsopyrazam (IPZ) is one of the broad-spectrum succinate dehydrogenase inhibitor fungicides (SDHIs). Although the potential bio-toxicity of SDHIs has been reported hourly, the specific effects focused on the cardiovascular system have remained unclear and piecemeal. Thus, we chose IPZ as a representative to observe the cardiovascular toxicity of SDHIs in zebrafish. Two types of transgenic zebrafish, Tg (cmlc2:GFP) and Tg (flk1:GFP) were used in this study. Healthy embryos at 6 hpf were exposed to IPZ solutions. The sta...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 10, 2023 Category: Environmental Health Authors: Yuepei Yan Shuang Liang Tao Zhang Chengchen Deng Huili Li Dechuan Zhang Daoxi Lei Guixue Wang Source Type: research

Acute exposure of Isopyrazam damages the developed cardiovascular system of zebrafish (Danio rerio)
J Environ Sci Health B. 2023 Apr 9:1-11. doi: 10.1080/03601234.2023.2197655. Online ahead of print.ABSTRACTIsopyrazam (IPZ) is one of the broad-spectrum succinate dehydrogenase inhibitor fungicides (SDHIs). Although the potential bio-toxicity of SDHIs has been reported hourly, the specific effects focused on the cardiovascular system have remained unclear and piecemeal. Thus, we chose IPZ as a representative to observe the cardiovascular toxicity of SDHIs in zebrafish. Two types of transgenic zebrafish, Tg (cmlc2:GFP) and Tg (flk1:GFP) were used in this study. Healthy embryos at 6 hpf were exposed to IPZ solutions. The sta...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 10, 2023 Category: Environmental Health Authors: Yuepei Yan Shuang Liang Tao Zhang Chengchen Deng Huili Li Dechuan Zhang Daoxi Lei Guixue Wang Source Type: research

Acute exposure of Isopyrazam damages the developed cardiovascular system of zebrafish (Danio rerio)
J Environ Sci Health B. 2023;58(4):367-377. doi: 10.1080/03601234.2023.2197655. Epub 2023 Apr 9.ABSTRACTIsopyrazam (IPZ) is one of the broad-spectrum succinate dehydrogenase inhibitor fungicides (SDHIs). Although the potential bio-toxicity of SDHIs has been reported hourly, the specific effects focused on the cardiovascular system have remained unclear and piecemeal. Thus, we chose IPZ as a representative to observe the cardiovascular toxicity of SDHIs in zebrafish. Two types of transgenic zebrafish, Tg (cmlc2:GFP) and Tg (flk1:GFP) were used in this study. Healthy embryos at 6 hpf were exposed to IPZ solutions. The statis...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 10, 2023 Category: Environmental Health Authors: Yuepei Yan Shuang Liang Tao Zhang Chengchen Deng Huili Li Dechuan Zhang Daoxi Lei Guixue Wang Source Type: research

Acute exposure of Isopyrazam damages the developed cardiovascular system of zebrafish (Danio rerio)
J Environ Sci Health B. 2023;58(4):367-377. doi: 10.1080/03601234.2023.2197655. Epub 2023 Apr 9.ABSTRACTIsopyrazam (IPZ) is one of the broad-spectrum succinate dehydrogenase inhibitor fungicides (SDHIs). Although the potential bio-toxicity of SDHIs has been reported hourly, the specific effects focused on the cardiovascular system have remained unclear and piecemeal. Thus, we chose IPZ as a representative to observe the cardiovascular toxicity of SDHIs in zebrafish. Two types of transgenic zebrafish, Tg (cmlc2:GFP) and Tg (flk1:GFP) were used in this study. Healthy embryos at 6 hpf were exposed to IPZ solutions. The statis...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 10, 2023 Category: Environmental Health Authors: Yuepei Yan Shuang Liang Tao Zhang Chengchen Deng Huili Li Dechuan Zhang Daoxi Lei Guixue Wang Source Type: research