Telangiectasias induced by combination tucatinib and ado-trastuzumab emtansine in a patient with metastatic breast cancer
CONCLUSIONS: We postulate that telangiectasias may be a previously unreported dermatologic side effect of combination treatment with tucatinib and T-DM1. Electrocautery is a safe and effective procedure to reduce the appearance of telangiectasias and improve patient satisfaction during chemotherapy.PMID:38578876 | DOI:10.3233/BD-230053 (Source: Breast Disease)
Source: Breast Disease - April 5, 2024 Category: Cancer & Oncology Authors: Gabriella F Rodriguez Anuj Shah Andrea D Maderal Source Type: research
Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials
Ductal Carcinoma In Situ (DCIS) can progress to invasive breast cancer, but most DCIS lesions never will. Therefore, four clinical trials (COMET, LORIS, LORETTA, AND LORD) test whether active surveillance for ... (Source: Cancer Imaging)
Source: Cancer Imaging - April 5, 2024 Category: Radiology Authors: Sena Alaeikhanehshir, Madelon M. Voets, Frederieke H. van Duijnhoven, Esther H. lips, Emma J. Groen, Marja C. J. van Oirsouw, Shelley E. Hwang, Joseph Y. Lo, Jelle Wesseling, Ritse M. Mann and Jonas Teuwen Tags: Research article Source Type: research
Cancers, Vol. 16, Pages 1417: Safety of the Breast Cancer Adjuvant Radiotherapy in Ataxia & ndash;Telangiectasia Mutated Variant Carriers
Cancers, Vol. 16, Pages 1417: Safety of the Breast Cancer Adjuvant Radiotherapy in Ataxia–Telangiectasia Mutated Variant Carriers
Cancers doi: 10.3390/cancers16071417
Authors:
Rayan Bensenane
Arnaud Beddok
Fabienne Lesueur
Alain Fourquet
Mathilde Warcoin
Marine Le Mentec
Eve Cavaciuti
Dorothée Le Gal
Séverine Eon-Marchais
Nadine Andrieu
Dominique Stoppa-Lyonnet
Youlia Kirova
The Ataxia–Telangiectasia Mutated (ATM) gene is implicated in DNA double-strand break repair. Controversies in clinical radiosensitivity remain known for monoallelic carriers of the ATM pathogenic...
Source: Cancers - April 5, 2024 Category: Cancer & Oncology Authors: Rayan Bensenane Arnaud Beddok Fabienne Lesueur Alain Fourquet Mathilde Warcoin Marine Le Mentec Eve Cavaciuti Doroth ée Le Gal S éverine Eon-Marchais Nadine Andrieu Dominique Stoppa-Lyonnet Youlia Kirova Tags: Article Source Type: research
AI analytics can be used as imaging biomarkers for predicting invasive upgrade of ductal carcinoma in situ
ConclusionThe AI-CAD score was an independent predictor of invasive upgrade for DCIS. Higher AI-CAD scores, especially in the highest quartile of ≥ 75%, can be used as an objective imaging biomarker to predict invasive upgrade in DCIS diagnosed with percutaneous biopsy.Critical relevance statementNoninvasive imaging features including the quantitative results of AI-CAD for mammography interpretation were independent predictors of invasive upgrade in lesions initially diagnosed as ductal carcinoma in situ via percutaneous biopsy and therefore may help decide the direction of surgery before treatment.Key points• Predicti...
Source: Insights into Imaging - April 5, 2024 Category: Radiology Source Type: research
Systematic review and meta-analysis of prognostic characteristics for breast cancers in populations with digital versus film mammography indicate the transition may have increased both early detection and overdiagnosis
CONCLUSION: The increased detection of all grades of DCIS and invasive cancer may indicate both increased early detection of more aggressive disease and increased overdiagnosis.FUNDING: Australian National Health and Medical Research Council and the National Breast Cancer Foundation.REGISTRATION: PROSPERO 2017:CRD42017070601.PMID:38570078 | DOI:10.1016/j.jclinepi.2024.111339 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 3, 2024 Category: Cancer & Oncology Authors: Rachel Farber Michael L Marinovich Audrey Pinna Nehmat Houssami Kevin McGeechan Alexandra Barratt Katy Jl Bell Source Type: research
Systematic review and meta-analysis of prognostic characteristics for breast cancers in populations with digital versus film mammography indicate the transition may have increased both early detection and overdiagnosis
CONCLUSION: The increased detection of all grades of DCIS and invasive cancer may indicate both increased early detection of more aggressive disease and increased overdiagnosis.FUNDING: Australian National Health and Medical Research Council and the National Breast Cancer Foundation.REGISTRATION: PROSPERO 2017:CRD42017070601.PMID:38570078 | DOI:10.1016/j.jclinepi.2024.111339 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 3, 2024 Category: Cancer & Oncology Authors: Rachel Farber Michael L Marinovich Audrey Pinna Nehmat Houssami Kevin McGeechan Alexandra Barratt Katy Jl Bell Source Type: research
Outcomes of atypical (B3) core biopsy lesions diagnosed across BreastScreen NSW, Australia
CONCLUSIONS: The overall upgrade rate of B3 lesions to malignancy was 26.4%. The majority of the lesions were upgraded to DCIS instead of invasive cancer. Upgrade rates varied by lesion type. Lesions with atypia had significantly higher upgrade rates to cancer compared to lesions without atypia. Malignant lesions were significantly larger than benign lesions.PMID:38564975 | DOI:10.1016/j.breast.2024.103720 (Source: Breast)
Source: Breast - April 2, 2024 Category: Cancer & Oncology Authors: Richard Chou Diana Tran Joseph Descallar Bin Jalaludin Patsy S Soon Source Type: research
Outcomes of atypical (B3) core biopsy lesions diagnosed across BreastScreen NSW, Australia
CONCLUSIONS: The overall upgrade rate of B3 lesions to malignancy was 26.4%. The majority of the lesions were upgraded to DCIS instead of invasive cancer. Upgrade rates varied by lesion type. Lesions with atypia had significantly higher upgrade rates to cancer compared to lesions without atypia. Malignant lesions were significantly larger than benign lesions.PMID:38564975 | PMC:PMC10993176 | DOI:10.1016/j.breast.2024.103720 (Source: Breast)
Source: Breast - April 2, 2024 Category: Cancer & Oncology Authors: Richard Chou Diana Tran Joseph Descallar Bin Jalaludin Patsy S Soon Source Type: research
Outcomes of atypical (B3) core biopsy lesions diagnosed across BreastScreen NSW, Australia
CONCLUSIONS: The overall upgrade rate of B3 lesions to malignancy was 26.4%. The majority of the lesions were upgraded to DCIS instead of invasive cancer. Upgrade rates varied by lesion type. Lesions with atypia had significantly higher upgrade rates to cancer compared to lesions without atypia. Malignant lesions were significantly larger than benign lesions.PMID:38564975 | PMC:PMC10993176 | DOI:10.1016/j.breast.2024.103720 (Source: Breast)
Source: Breast - April 2, 2024 Category: Cancer & Oncology Authors: Richard Chou Diana Tran Joseph Descallar Bin Jalaludin Patsy S Soon Source Type: research
Outcomes of atypical (B3) core biopsy lesions diagnosed across BreastScreen NSW, Australia
CONCLUSIONS: The overall upgrade rate of B3 lesions to malignancy was 26.4%. The majority of the lesions were upgraded to DCIS instead of invasive cancer. Upgrade rates varied by lesion type. Lesions with atypia had significantly higher upgrade rates to cancer compared to lesions without atypia. Malignant lesions were significantly larger than benign lesions.PMID:38564975 | PMC:PMC10993176 | DOI:10.1016/j.breast.2024.103720 (Source: Breast)
Source: Breast - April 2, 2024 Category: Cancer & Oncology Authors: Richard Chou Diana Tran Joseph Descallar Bin Jalaludin Patsy S Soon Source Type: research
Outcomes of atypical (B3) core biopsy lesions diagnosed across BreastScreen NSW, Australia
CONCLUSIONS: The overall upgrade rate of B3 lesions to malignancy was 26.4%. The majority of the lesions were upgraded to DCIS instead of invasive cancer. Upgrade rates varied by lesion type. Lesions with atypia had significantly higher upgrade rates to cancer compared to lesions without atypia. Malignant lesions were significantly larger than benign lesions.PMID:38564975 | PMC:PMC10993176 | DOI:10.1016/j.breast.2024.103720 (Source: Breast)
Source: Breast - April 2, 2024 Category: Cancer & Oncology Authors: Richard Chou Diana Tran Joseph Descallar Bin Jalaludin Patsy S Soon Source Type: research
