Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity
AbstractThe three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral aspects of the breast tissue, and they have important roles during mammary gland development, function and malignancy. However, the architecture of the branched mammary epithelial network is poorly recapitulated in the current in vitro models. 3D bioprinting is an emerging approach to improve tissue-mimicry in cell culture. Here, we developed and optimized a protocol for 3D bioprinting of normal and cancerous mammary epithelial cells into a branched Y-shape to study the role of cell positioning ...
Source: Journal of Mammary Gland Biology and Neoplasia - February 28, 2024 Category: Cancer & Oncology Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
Value of magnetic resonance imaging radiomics features in predicting histologic grade of invasive ductal carcinoma of the breast
CONCLUSION: ADC values and breast MRI radiomics signatures are significant in identifying the histological grades of IDC, with the ADC radiomics signatures having greater value.PMID:38393931 | DOI:10.3233/THC-230671 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Xin-Lei Yang Dong-He Ni Yang Yu Jin-Cui Zhao Rui Lin Chao Xiu Zhe-Xing Chang Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | PMC:PMC10887948 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
Value of magnetic resonance imaging radiomics features in predicting histologic grade of invasive ductal carcinoma of the breast
CONCLUSION: ADC values and breast MRI radiomics signatures are significant in identifying the histological grades of IDC, with the ADC radiomics signatures having greater value.PMID:38393931 | DOI:10.3233/THC-230671 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Xin-Lei Yang Dong-He Ni Yang Yu Jin-Cui Zhao Rui Lin Chao Xiu Zhe-Xing Chang Source Type: research
Immune cell infiltrate in ductal carcinoma in situ and the risk of dying from breast cancer: case-control study
CONCLUSION: The immune response to DCIS may influence the risk of dying from breast cancer.PMID:38395442 | PMC:PMC10890909 | DOI:10.1093/bjs/znae037 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - February 23, 2024 Category: Surgery Authors: Gunilla Rask Charlotta Wadsten Balazs Acs Johan Hartman Irma Fredriksson Hans Garmo Fredrik W ärnberg Malin Sund Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | PMC:PMC10887948 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
Value of magnetic resonance imaging radiomics features in predicting histologic grade of invasive ductal carcinoma of the breast
CONCLUSION: ADC values and breast MRI radiomics signatures are significant in identifying the histological grades of IDC, with the ADC radiomics signatures having greater value.PMID:38393931 | DOI:10.3233/THC-230671 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Xin-Lei Yang Dong-He Ni Yang Yu Jin-Cui Zhao Rui Lin Chao Xiu Zhe-Xing Chang Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | PMC:PMC10887948 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
Value of magnetic resonance imaging radiomics features in predicting histologic grade of invasive ductal carcinoma of the breast
CONCLUSION: ADC values and breast MRI radiomics signatures are significant in identifying the histological grades of IDC, with the ADC radiomics signatures having greater value.PMID:38393931 | DOI:10.3233/THC-230671 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Xin-Lei Yang Dong-He Ni Yang Yu Jin-Cui Zhao Rui Lin Chao Xiu Zhe-Xing Chang Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | PMC:PMC10887948 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
Value of magnetic resonance imaging radiomics features in predicting histologic grade of invasive ductal carcinoma of the breast
CONCLUSION: ADC values and breast MRI radiomics signatures are significant in identifying the histological grades of IDC, with the ADC radiomics signatures having greater value.PMID:38393931 | DOI:10.3233/THC-230671 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Xin-Lei Yang Dong-He Ni Yang Yu Jin-Cui Zhao Rui Lin Chao Xiu Zhe-Xing Chang Source Type: research
Personalizing the Treatment of Women with Ductal Carcinoma In Situ (DCIS) Using the DCIS Score: A Qualitative Study on Score Use
CONCLUSIONS: ROs had concerns about the overtreatment of women with DCIS, but lacked the tools to reliably predict which women could safely avoid radiation. By providing oncologists and women with personalized tumor information, the DCIS score was an important component of treatment decision making.PMID:38392067 | PMC:PMC10887948 | DOI:10.3390/curroncol31020073 (Source: Current Oncology)
Source: Current Oncology - February 23, 2024 Category: Cancer & Oncology Authors: Mary Ann O'Brien Lawrence Paszat Tutsirai Makuwaza Cindy Fong Eileen Rakovitch Source Type: research
