Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecuar mechanisms
Crit Rev Microbiol. 2024 Apr 11:1-31. doi: 10.1080/1040841X.2024.2339260. Online ahead of print.ABSTRACTPeriodontitis is an immuno-inflammatory disease of the soft tissues surrounding the teeth. Periodontitis is linked to many communicable and non-communicable diseases such as diabetes, cardiovascular disease, rheumatoid arthritis, and cancers. The oral-systemic link between periodontal disease and systemic diseases is attributed to the spread of inflammation, microbial products and microbes to distant organ systems. Oral bacteria reach the gut via swallowed saliva, whereby they induce gut dysbiosis and gastrointestinal dy...
Source: Critical Reviews in Microbiology - April 11, 2024 Category: Microbiology Authors: Sayantan Mukherjee Aditi Chopra Shaswata Karmakar Subraya Giliyar Bhat Source Type: research

Association of imaging and pathological findings of breast cancer in very young women: Report of a twenty-year retrospective study
CONCLUSION: Our study shows the most common subtype to be Luminal A cancer, with 74 % of the tumors being larger than 2 cm at the time of diagnosis. Irregular masses with non-circumscribed margins were the most common imaging findings.PMID:38599926 | DOI:10.1016/j.clinimag.2024.110094 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Sepideh Sefidbakht Zahra Beizavi Fatemeh Kanaani Nejad Parisa Pishdad Nahid Sadighi Masoumeh Ghoddusi Johari Bijan Bijan Sedigheh Tahmasebi Source Type: research

Association of imaging and pathological findings of breast cancer in very young women: Report of a twenty-year retrospective study
CONCLUSION: Our study shows the most common subtype to be Luminal A cancer, with 74 % of the tumors being larger than 2 cm at the time of diagnosis. Irregular masses with non-circumscribed margins were the most common imaging findings.PMID:38599926 | DOI:10.1016/j.clinimag.2024.110094 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Sepideh Sefidbakht Zahra Beizavi Fatemeh Kanaani Nejad Parisa Pishdad Nahid Sadighi Masoumeh Ghoddusi Johari Bijan Bijan Sedigheh Tahmasebi Source Type: research

Association of imaging and pathological findings of breast cancer in very young women: Report of a twenty-year retrospective study
CONCLUSION: Our study shows the most common subtype to be Luminal A cancer, with 74 % of the tumors being larger than 2 cm at the time of diagnosis. Irregular masses with non-circumscribed margins were the most common imaging findings.PMID:38599926 | DOI:10.1016/j.clinimag.2024.110094 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Sepideh Sefidbakht Zahra Beizavi Fatemeh Kanaani Nejad Parisa Pishdad Nahid Sadighi Masoumeh Ghoddusi Johari Bijan Bijan Sedigheh Tahmasebi Source Type: research

Association of imaging and pathological findings of breast cancer in very young women: Report of a twenty-year retrospective study
CONCLUSION: Our study shows the most common subtype to be Luminal A cancer, with 74 % of the tumors being larger than 2 cm at the time of diagnosis. Irregular masses with non-circumscribed margins were the most common imaging findings.PMID:38599926 | DOI:10.1016/j.clinimag.2024.110094 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Sepideh Sefidbakht Zahra Beizavi Fatemeh Kanaani Nejad Parisa Pishdad Nahid Sadighi Masoumeh Ghoddusi Johari Bijan Bijan Sedigheh Tahmasebi Source Type: research

STK3 higher expression association with clinical characteristics in intrinsic subtypes of breast cancer invasive ductal carcinoma patients
ConclusionBy introducing a novel bioinformatics approach that combines GSEA and WSM, the study successfully identified the top 5% of genes associated with higher expression of STK3. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - April 9, 2024 Category: Cancer & Oncology Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Genitourinary Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Breast Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research

Clinical Longevity of Preoperative Injection of Superparamagnetic Iron Oxide Nanoparticles for Delayed Sentinel Lymph Node Biopsy
We present our experience with a patient who due to complications from surgery could not complete her d-SLNB for 165 days. The SPIO tracer remained active in the lymph node and remained clinically useful for this five and a half month gap from time of injection. Further study is needed to determine the clinical longevity of SPIO in a lymph node.PMID:38576134 | DOI:10.1177/00031348241244634 (Source: The American Surgeon)
Source: The American Surgeon - April 5, 2024 Category: Surgery Authors: Gael Muanamputu Brian K Sparkman Raphael J Louie Kandace P McGuire Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Breast Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Genitourinary Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research

Telangiectasias induced by combination tucatinib and ado-trastuzumab emtansine in a patient with metastatic breast cancer
CONCLUSIONS: We postulate that telangiectasias may be a previously unreported dermatologic side effect of combination treatment with tucatinib and T-DM1. Electrocautery is a safe and effective procedure to reduce the appearance of telangiectasias and improve patient satisfaction during chemotherapy.PMID:38578876 | DOI:10.3233/BD-230053 (Source: Breast Disease)
Source: Breast Disease - April 5, 2024 Category: Cancer & Oncology Authors: Gabriella F Rodriguez Anuj Shah Andrea D Maderal Source Type: research

Clinical Longevity of Preoperative Injection of Superparamagnetic Iron Oxide Nanoparticles for Delayed Sentinel Lymph Node Biopsy
We present our experience with a patient who due to complications from surgery could not complete her d-SLNB for 165 days. The SPIO tracer remained active in the lymph node and remained clinically useful for this five and a half month gap from time of injection. Further study is needed to determine the clinical longevity of SPIO in a lymph node.PMID:38576134 | DOI:10.1177/00031348241244634 (Source: The American Surgeon)
Source: The American Surgeon - April 5, 2024 Category: Surgery Authors: Gael Muanamputu Brian K Sparkman Raphael J Louie Kandace P McGuire Source Type: research

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement
Indian J Clin Biochem. 2024 Apr;39(2):214-220. doi: 10.1007/s12291-023-01129-0. Epub 2023 Mar 30.ABSTRACTBreast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Fem...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Sanchi Sukhija Purvi Purohit Puneet Pareek Pawan Kumar Garg Jeewan Ram Vishnoi Poonam Abhay Elhence Shobhan Babu Varthya Praveen Sharma Sneha Ambwani Jaykaran Charan Source Type: research