Small breast Schwannoma in an old female; a case report.
We report a case which was presented to and managed in the Oncology center, Mansoura University in November 2017. PMID: 31045508 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - May 4, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Infiltration of CD4, CD8, CD56, and Fox-P3-positive lymphocytes in breast carcinoma tissue after neoadjuvant chemotherapy with or without trastuzumab.
CONCLUSIONS: The results suggest that Tz therapy induces adaptive cellular immunity, including infiltration of both CD4-positive helper T cells and CD8-positive cytotoxic T cells into the breast carcinoma lesion. PMID: 31006655 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - April 24, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Upstaging papillary lesions to carcinoma on surgical excision is not impacted by patient race.
CONCLUSIONS: Atypia remains the most significant contributor to the risk of upstaging papillary lesions to malignancy. Our research supports the practice of excising all atypical papillary lesions with selected excision of those without atypia. In our cohort, there was no association between race and risk of upstaging to malignacy. PMID: 30988233 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - April 18, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Inter-laboratory comparison of Ki-67 proliferating index detected by visual assessment and automated digital image analysis.
CONCLUSION: Proliferation remains one of the most important parameters for tumor characterization helpful in making clinical decisions, but it should be used with great caution. Standardization of the Ki-67 assessment is essential and proliferating index should be expressed as exact numeric value. For patients with proliferative index near the cut-off value, other factors must be considered in making clinical decisions. PMID: 30958325 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - April 9, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Performance of survivin mRNA as a biomarker for breast cancer among Vietnamese women.
CONCLUSION: Results provide the initial evidence of the expression of survivin mRNA in breast cancer patients in Vietnam, suggesting the role of survivin mRNA in breast cancer molecular pathology. PMID: 30958326 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - April 9, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Oncology nurses' knowledge about Lymphedema Assessment, Prevention, and  Management among Women with Breast Cancer.
This study was conducted to evaluate the oncology nurses' knowledge about lymphedema assessment, prevention, and management among women with breast cancer, and identify the relationships between oncology nurses' academic qualification, years of experience, and level of knowledge. METHODS: A cross-sectional descriptive design was used. A sample of 150 participants from three institutions completed the study surveys. RESULTS: 60% (N = 90) of the participants did not pass the knowledge test. 70% (N = 105) of the participants showed lack of knowledge regarding BCRL assessment and examination. The results show...
Source: Breast Disease - April 9, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

A comparative analysis of axillary nodal burden in ultrasound/biopsy positive axilla vs ultrasound negative sentinel lymph node biopsy positive axilla.
Authors: Tandon M, Ball W, Kirby R, Soumian S, Narayanan S Abstract BACKGROUND: Axillary Ultrasound (AUS) is now performed as a protocol in every newly diagnosed breast cancer in most European countries. It is an inexpensive and sensitive tool in hands of a trained operator. All AUS negative patients undergo Sentinel Lymph Node Biopsy (SLNB), while AUS positive patients bypass SLNB and undergo axillary nodal clearance (ANC) as a standard protocol. We wish to analyse these two groups to see if ANC can be foregone in these patients. AIMS AND OBJECTIVES: To compare and analyse the axillary disease burden in early ...
Source: Breast Disease - March 26, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

A clinicopathological study of fibroadenomas with epithelial proliferation including lobular carcinoma in-situ, atypical ductal hyperplasia, DCIS and invasive carcinoma.
CONCLUSION: In our study population, the most common type of carcinoma arising in fibroadenomas was DCIS, followed by lobular carcinoma in-situ. Lobular carcinoma in-situ was more likely to be confined to the fibroadenoma while most DCIS involved surrounding breast tissue. PMID: 30909180 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - March 26, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Metastatic breast cancer to the adductor magnus; a case report and literature overview.
We report a case of a patient with a history of stage IIA infiltrating lobular carcinoma of the right breast presenting with a metastatic lesion in the right adductor magnus. She was treated four years prior to the onset of the metastases with a modified radical mastectomy but refused postoperative chemotherapy or adjunctive radiation. PMID: 30856097 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - March 13, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Breast cancer section analysis correlates with sentinel lymph node biopsies: Precision and topographic anatomy.
CONCLUSIONS: The correlation between the SLN topographic anatomical position and the pathology results, revealed that the majority of the SLN accumulates in the front axillary region. A larger patient population will statistically support this association. PMID: 30829609 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - March 6, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

DSCAM-AS1 up-regulation in invasive ductal carcinoma of breast and assessment of its potential as a diagnostic biomarker.
CONCLUSIONS: The significant up-regulation of DSCAM-AS1 in tumoral tissues compared with ANCTs provides further evidences for participation of this lncRNA in the pathogenesis of breast cancer. PMID: 30594914 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - January 1, 2019 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Expression of urokinase plasminogen activator (uPA) in the leukocytes and tissues of patients with benign and malignant breast lesions.
Authors: Barberi S, Montagna G, Rossi L Abstract OBJECTIVE: to show that the expression of urokinase plasminogen activator (uPA) in the leucocytes of patients with benign and malignant breast lesions correlates with its expression in the lesions, and to explore the role of uPA as a tumour marker in breast cancer. METHODS: using real time reverse transcriptase - polymerase chain reaction (RT-PCR), we examined the expression of uPA in leukocytes and tissues of three groups of women: a) with breast cancer (BC), b) with benign breast lesions and c) a control group of healthy women. An arbitrary value of 1 was assig...
Source: Breast Disease - December 21, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Recurrent Mondor's breast disease - hormonal contraceptive involvement.
Authors: Lambat Emery S, Kalovidouri A, David-Montefiore E Abstract Mondor's disease can be a challenging diagnosis. The case we present is of a 29 year-old Brazilian woman, under combined hormonal contraception, who consulted for a painful lump on her right breast. She presented a complete resolution after a local treatment of heparinoid cream and a non-steroidal anti-inflammatory oral treatment, but relapsed 18 months later. Oral combined hormonal contraception was the only "risk factor" found, in this case, and the modification of the latter helped resolve the relapse clinical symptoms. PMID: 30530...
Source: Breast Disease - December 12, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Re-excision rate after sector resection for breast cancer: A 5-year retrospective cohort study.
CONCLUSION: BCS using the sector resection technique has a low re-excision rate for positive margins. Younger patients and aggressive tumour biology are important predictive risk factors for positive margins. PMID: 30198861 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - September 12, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Prospective comparative study assessing role of ultrasound versus thermography in breast cancer detection.
CONCLUSION: We believe that thermography is a non-invasive, safe, and accepted method by patients; however, despite technical advances in it, its diagnostic abilities are still less than those of sonography, so we suggest that it be used as an adjunct in breast cancer diagnosis in selective situations. PMID: 30124439 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - August 22, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Ductal carcinoma in-situ, cystic hypersecretory type presented by recurrent hemorrhagic cyst.
We reported the first case report of ductal carcinoma in-situ, hypersecretory type, presented by a hemorrhagic cyst. PMID: 30124440 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - August 22, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Molecular prevalence of human papillomavirus infection among Iranian women with breast cancer.
CONCLUSION: The low frequency of HPV detected in our study does not support an association between breast carcinoma and HPV infection. However, it is possible that HPV may be responsible for breast carcinogenesis only in small percentage of all breast cancer. PMID: 30124441 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - August 22, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Role of radiotherapy in women over the age of 65 after breast conserving surgery for breast cancer: A 5-year retrospective study.
CONCLUSIONS: XRT in women over the age of 65 did not decrease the risk of LR. Adjuvant XRT in older women should be offered to selective patients with high risk patient and tumour factors. PMID: 30124442 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - August 22, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Overall survival of elderly patients with breast cancer is not related to breast-cancer specific survival: A single institution experience in Japan.
Authors: Takuwa H, Tsuji W, Yotsumoto F Abstract BACKGROUND: As the aging population grows, the number of elderly breast cancer patients has rapidly increased especially in Japan; a suitable treatment for elderly patients, considering chronic comorbidities and treatment tolerance, is urgently needed. METHODS: In this retrospective study, 286 elderly breast cancer patients were investigated. Tumor characteristics and survival outcome were compared between 70-79-year-old and ≥ 80-year-old groups. Disease-free survival, overall survival, and breast cancer-specific survival were compared, and the effect of varia...
Source: Breast Disease - April 18, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Huge mucinous carcinoma of the breast in which doubling time was observed by computed tomography during 3 years without treatment.
Authors: Nakata B, Kuroda K, Yoshida Y, Iimori N, Masuda G, Lee T, Tendo M, Hori T, Sato H, Ishikawa T Abstract Here we report the case of a 77-year-old woman with a huge cancer of the right breast for which size was measured on computed tomography in our hospital preoperatively and in other hospital 3 years earlier. During the 3-year untreated interval, the tumor grew from 4 cm to 13 cm in maximum diameter, and the tumor-volume doubling time (TVDT) was calculated as 209 days. The patient underwent mastectomy with axillary lymph node dissection, with the large skin defect covered by autologous skin graft. The patho...
Source: Breast Disease - March 28, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Intracystic breast carcinoma. An important differential diagnosis in postmenopausal patients presenting with a rapidly growing breast cyst. Management and literature review.
Authors: Salemis NS Abstract Intracystic breast carcinoma is a rare clinical entity accounting for 0.5-2% of all breast cancers. It represents a distinctive clinical form rather a histological subtype of breast cancer and can either be in situ or invasive tumor. We herein describe a rare case of intracystic breast carcinoma arising from the wall of a cyst in a postmenopausal patient, who presented with a rapidly growing complex breast cyst. Diagnostic evaluation and management of the patient are discussed along with a review of the literature. Complex breast cysts may represent a diagnostic and therapeutic challeng...
Source: Breast Disease - March 28, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

The relationship between serum E2 levels and recurrence in premenopausal, ER-positive breast cancer patients: A retrospective study.
CONCLUSION: Among patients who received endocrine therapy without adjuvant chemotherapy, those with longer LHRH-a exposure had favorable prognoses. A potential association was observed between recurrence and E2 concentrations in women with premenopausal ER-positive early-stage breast cancer. PMID: 29578459 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - March 28, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Synchronous and metachronous breast cancer in Ukraine.
CONCLUSIONS: There should be paid a great attention to synchronous and metachronous breast cancer patients in order to find and provide the best options of their management. This is crucial to continue researches in this field of oncology. PMID: 29504518 [PubMed - in process] (Source: Breast Disease)
Source: Breast Disease - March 8, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Metaplastic carcinoma of the breast with mesenchymal differentiation (carcinosarcoma). A unique presentation of an aggressive malignancy and literature review.
Authors: Salemis NS Abstract Metaplastic carcinoma of the breast with mesenchymal differentiation (MCMD), previously known as carcinosarcoma, is a very rare and aggressive tumor that has been recently classified as a subtype of metaplastic breast carcinoma. It accounts for 0.08%-0.2% of all breast cancers, with only a few cases reported in the literature. Histologically, MCMD is characterized by a biphasic pattern of malignant epithelial and sarcomatous components without evidence of a transition zone between the two elements. We herein describe a unique case of metaplastic carcinoma of the breast with chondrosarco...
Source: Breast Disease - March 6, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Forkhead box M1 (FOXM1) expression predicts disease free survival and may mediate resistance to chemotherapy and hormonotherapy in male breast cancer.
Authors: Abdeljaoued S, Bettaieb L, Nasri M, Adouni O, Goucha A, Bouzaiene H, Boussen H, Rahal K, Gamoudi A Abstract BACKGROUND: Male breast cancer (MBC) is a rare and neglected disease. Prognostic and predictive factors in MBC are extrapoled from trials conducted on its female counterpart. OBJECTIVE: Since the relationship between the transcription factor Forkhead box M1 (FOXM1) expression and the clinical response to chemotherapy and hormonotherapy in MBC remains unknown, we sought to investigate the predictive value of FOXM1 in MBC. METHODS: FOXM1 expression was assessed in 130 MBC cases. Clinical signif...
Source: Breast Disease - March 6, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Isolated metachronous breast metastasis from Renal Cell carcinoma: A report of two cases.
We report two cases of isolated metachronous metastases to breast from renal cell carcinoma. PMID: 29376843 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - January 31, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Clinico-pathologic disparities of breast cancer in Hispanic/Latina women.
Authors: Nahleh Z, Botrus G, Dwivedi A, Badri N, Otoukesh S, Diab N, Biswas S, Jennings M, Elzamly S Abstract BACKGROUND: Breast cancer is the leading cause of cancer death in Hispanic/Latina women nationwide. Limited cancer research has been conducted in this population. El Paso, Texas is a large border city with a population of around 900,000, of which 85% are Latinos and would provide a suitable setting for this study. The aim of this study is to evaluate ethnic differences and cancer characteristics in Hispanic/latina women with breast cancer. METHODS: After IRB approval, we retrospectively analyzed the var...
Source: Breast Disease - January 31, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Phyllodes tumors of the breast: clinicopathological analysis of 106 cases from a single institution.
Authors: Efared B Abstract BACKGROUND: Phyllodes tumors (PT) are uncommon biphasic tumors, accounting for less than 1% of all breast primary neoplasms. They form a wide variety of tumors ranging from benign to malignant. Several histological features are used to grade PT into 3 categories: benign (grade I), borderline (grade II) and malignant (grade III) tumors. The aim of our study was to analyse histolopathological, radiological and clinical features of PT from an experience of a single center. METHODS: It was a retrospective study including 106 patients diagnosed with phyllodes tumors on surgi...
Source: Breast Disease - January 16, 2018 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Primary breast angiosarcoma - a single institution experience from a tertiary cancer center in South  India.
CONCLUSION: Due to a small number of this malignancy randomized studies are difficult to perform and optimum treatment strategy still need to be defined. PMID: 29286911 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - December 31, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Cytological diagnosis of crystallizing galactocele - report of an unusual case.
We report this case because of rarity of this condition and to the best of our knowledge, till date only five cases of crystallizing galactocele has been reported in medical literature. PMID: 29286912 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - December 31, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

First site of recurrence after breast cancer adjuvant treatment in the era of multimodality therapy: which imaging for which patient during follow-up?
CONCLUSION: Outcome of loco-regional and bone relapses was good, suggesting that both systematic mammography and bone-scan/CT scan for high risk patients (N+, gradeIII) during the first 2-3 years may represent a tailored relevant follow-up protocol for breast cancer patients. PMID: 29171964 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - November 26, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

The enigma of granulomatous mastitis: A series.
We report our experience with the diagnosis and management of eighteen cases of granulomatous mastitis in the setting of an urban public hospital. The patients were identified after a retrospective review of pathology and surgery databases. Demographic, clinical, radiographic, histopathological data and treatment responses were reviewed. Out of a total of 18 patients, 8 patients were noted to be from Mexico. The mean age at presentation was 35 years and 11 of the 18 patients reported a pregnancy in the last four years. Most cases were unsuccessfully managed as bacterial breast infections initially; definitive treatment inv...
Source: Breast Disease - November 1, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Follow-up of patients undergoing oncoplastic surgery - more palpable masses and benign biopsies.
We examined the findings on breast exam and imaging of patients who underwent breast conservation with or without oncoplastic reconstruction. OBJECTIVE: We hypothesized that patients undergoing immediate breast reconstruction would present with more palpable and imaging abnormalities compared to lumpectomy alone and undergo therefore more biopsies. METHODS: All patients undergoing breast conservation with oncoplastic reconstruction for breast cancer between 2009 and 2014 were included in the study group. The control group was created by matching 4 women that underwent lumpectomy alone during the same week to each p...
Source: Breast Disease - October 8, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Analysis of patient-detected breast cancer recurrence.
Authors: Kapoor T, Wrenn S, Callas P, James TA Abstract BACKGROUND: After primary surgical resection, breast cancer survivors regularly undergo surveillance using multiple modalities to detect recurrences. OBJECTIVE: The goal of this study was to determine how breast cancer recurrences were detected in our sample population of breast cancer survivors. We hypothesize that the majority of recurrences are patient-detected. METHODS: This was a retrospective observational study evaluating patients with a detected breast cancer recurrence between 2010 and 2015. Patients were analyzed by initial detection modality...
Source: Breast Disease - September 2, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Breast fibroadenoma with pseudoangiomatous (PASH-like) stroma.
Authors: Bezic J, Srbljin J Abstract Pseudoangiomatous stromal hyperplasia (PASH) is a breast stromal change, histologically characterized by anastomosing, slit-like spaces lined by slender myofibroblasts and surrounded by dense collagenous stroma. Mass forming cases clinically and radiologically simulate fibroadenoma. A middle aged women presented with unpalpable breast nodule discovered on ultrasound examination. The ultrasound characteristics were typical for fibroadenoma, while fine-needle aspiration cytology was inconclusive. The histological examination of the lumpectomy specimen showed fibroadenoma with pecu...
Source: Breast Disease - August 6, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

The importance of tattoo pigment in sentinel lymph nodes.
CONCLUSIONS: In this cohort of patients with ipsilateral tattoos, removed more LNs lead to unnecessary excision which may important for increasing the risk of arm morbidity from SLN biopsy. However, the presence of tattoo pigment did not interfere with understaging for axillary mapping and it did not effect of pathological identification of SLNs positivity. PMID: 28697552 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - July 14, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

The overall 5-year survival rate of breast cancer among iranian women: A systematic review and meta-analysis of published studies.
CONCLUSION: The survival rate of BC was relatively low in Iran compared to developed countries. Hence, more effective measures have to be taken to increase these patients' survival. PMID: 28655117 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 30, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Giant juvenile fibroadenoma in a 9-year-old: A case presentation and review of the current literature.
We present a 9-year-old, pre-menstrual, Nigerian female with no known family history of breast masses or cancers who developed spontaneous giant fibroadenoma measuring approximately 13  cm × 13 cm. Rapid growth of a breast mass can be of great concern to such young patients whose breasts are in the early formative stages. It is important to promptly rule out malignant processes or phyllodes tumor, and educate young patients and their families on treatment options that fit their unique concerns and circumstances. PMID: 28655118 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 30, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Follow-up of granulomatous mastitis with monitoring versus surgery.
CONCLUSIONS: Patients who followed-up by observation should be explained that IGM is a chronic disease and that it may recur in certain periods. Clinical, radiological and pathological examinations should be performed together for breast cancer developing due to the chronical progresses of IGM or concurrent breast cancer. PMID: 28655119 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 30, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

A rare benign tumor of breast masquerading on fine needle aspiration cytology: A  case report.
We present an extremely rare case of pleomorphic adenoma of breast diagnosed on FNAC with histopathological confirmation. PMID: 28655120 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 30, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

High-grade poorly differentiated neuroendocrine carcinoma of the breast with low oncotype Dx recurrence score: A  case report.
High-grade poorly differentiated neuroendocrine carcinoma of the breast with low oncotype Dx recurrence score: A case report. Breast Dis. 2017 Jun 23;: Authors: Munoz-Zuluaga CA, Kotiah S, Studeman KD Abstract Primary neuroendocrine carcinoma of the breast (NECB) is a rare malignant tumor with controversial biological behavior and a lack of data guiding treatment decisions due to its scarcity. Cancer gene-expression profiling tests provide a better indication of clinical prognosis and help determine the best clinical management versus the traditional clinical and pathological parameters. This...
Source: Breast Disease - June 30, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Retinoic acid-related orphan receptor alpha (RORA) variants and risk of breast cancer.
CONCLUSIONS: The results of this study support a putative role for RORA in breast cancer pathogenesis. PMID: 28598825 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 11, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

The evaluation of the effect of metformin on breast fibrocystic disease.
Authors: Talaei A, Moradi A, Rafiei F PMID: 28598826 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 11, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Expression analysis of long non-coding ATB and its putative target in breast cancer.
CONCLUSION: Collectively, out data show downregulation of lncRNA-ATB in a significant number of breast tumor tissues compared with ANCTs and imply that lncRNA-ATB might have distinct roles in the pathogenesis of different cancers or even different subtypes of a certain cancer which should be evaluated in future studies. PMID: 28598827 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 11, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Gigantomastia due to retromammary lipoma: An aesthetic management.
CONCLUSION: This case demonstrates that reduction mammoplasty after giant lipoma removal is highly rewarding, resulting in a smaller-sized breast that is aesthetically more pleasing, has better symmetry with the contralateral breast, and provides relief from functional mass deficit. PMID: 28598828 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - June 11, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Impaired expression of Drosha in breast  cancer.
Impaired expression of Drosha in breast cancer. Breast Dis. 2017 Jun 02;: Authors: Poursadegh Zonouzi AA, Shekari M, Nejatizadeh A, Shakerizadeh S, Fardmanesh H, Poursadegh Zonouzi A, Rahmati-Yamchi M, Tozihi M Abstract BACKGROUND: Impaired miRNAs processing pathway is one interesting scenario for global downregulation of the miRNAome in various types of malignancy. We previously reported that DGCR8 and Dicer genes dysregulated in patients with breast cancer. OBJECTIVE: To evaluate the expression pattern of Drosha in patients with breast cancer. METHODS: We evaluated the mRNA expression le...
Source: Breast Disease - June 11, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Huge lactating adenoma of the breast: Case report.
Authors: Elzahaby IA, Saleh S, Metwally IH, Fathi A, Atallah K PMID: 28269736 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - March 9, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

A rare case of umbilical metastasis after delayed transverse rectus abdominis myocutaneous flap reconstruction for invasive breast cancer.
Authors: Seymour NC, Rathinaezhil R Abstract A 46-year-old female presented with an inflamed and painful umbilicus. Past medical history included breast cancer, followed by metastatic sternal cancer two years after the initial breast cancer diagnosis.The painful umbilicus was confirmed metastasis from a primary breast cancer she had treated eleven years previously.Metastases to the umbilicus are rare, and are usually gastrointestinal in origin. To our knowledge this is the first report of a metastasis from any primary cancer to the umbilicus after transverse rectus abdominis myocutaneous flap (TRAM). Any lesion at ...
Source: Breast Disease - January 1, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as prognostic factors in non-metastatic breast cancer patients from a Hispanic population.
Authors: Allan RE, Luis RP, Juan P PMID: 28035906 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - January 1, 2017 Category: Cancer & Oncology Tags: Breast Dis Source Type: research

Expression of TTF-1 in breast cancer independently of ER expression: A case report and pathogenic implications.
We present a case of ER-positive breast cancer in 30% of tumor cells that was also TTF-1 positive in some areas of the primary tumor but lost ER expression completely in the metastatic recurrence site while retaining TTF-1 positivity. Additionally, a PTEN mutation was present on genomic evaluation of the primary tumor. Diagnostic, pathogenic and therapeutic implications of these findings are discussed. PMID: 27983521 [PubMed - as supplied by publisher] (Source: Breast Disease)
Source: Breast Disease - December 18, 2016 Category: Cancer & Oncology Tags: Breast Dis Source Type: research