Cyclobenzaprine-Induced Hallucinosis.
Authors: Bulbena-Cabre A, Dunn NR, Swift RG
PMID: 26644954 [PubMed - as supplied by publisher] (Source: The Primary Care Companion for CNS Disorders)
Source: The Primary Care Companion for CNS Disorders - December 12, 2015 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
Cyclobenzaprine for acute back pain.
PMID: 26668287 [PubMed - in process] (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - December 1, 2015 Category: Primary Care Authors: Braschi E, Garrison S, Allan GM Tags: Can Fam Physician Source Type: research
Pharmacological Treatment of Acute Low Back Pain
This randomized trial compared improvement in functional outcomes among patients with low back pain discharged from the emergency department and receiving naproxen with either placebo, cyclobenzaprine, or oxycodone/acetaminophen. (Source: JAMA)
Source: JAMA - October 20, 2015 Category: Journals (General) Source Type: research
Retrospective Evaluation on the Analgesic Activities of 2 Compounded Topical Creams and Voltaren Gel in Chronic Noncancer Pain
The objective of this study was to evaluate the efficacy of 2 compounded topical creams, “Cream I” and “Cream II,” in patients with chronic extremity, joint, musculoskeletal, neuropathic, or other chronic topical pain conditions and compare their efficacy with Voltaren gel. The primary efficacy outcome was the change in visual numeric pain intensity score from pretreatment to posttreatment. The Cream I contained Flurbiprofen (20%), Tramadol (5%), Clonidine (0.2%), Cyclobenzaprine (4%), and Bupivacaine (3%). The Cream II contained Flurbiprofen (20%), Baclofen (2%), Clonidine (0.2%), Gabapentin (10%), and Lidocaine (...
Source: American Journal of Therapeutics - September 1, 2015 Category: Drugs & Pharmacology Tags: Original Articles Source Type: research
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report
Clinical Toxicology, Ahead of Print. (Source: Clinical Toxicology)
Source: Clinical Toxicology - May 9, 2015 Category: Toxicology Tags: article Source Type: research
Potentially Inappropriate Anticholinergic Medication Use in Community-Dwelling Older Adults: A National Cross-Sectional Study
Conclusion
The study found that approximately one in ten older adults used potentially inappropriate anticholinergic medications. Several predisposing, enabling and need factors were associated with the use of potentially inappropriate anticholinergic medications. Concerted efforts are needed to optimize potentially inappropriate anticholinergic medication use in older adults. (Source: Drugs and Aging)
Source: Drugs and Aging - April 1, 2015 Category: Geriatrics Source Type: research
Element Determination in Pharmaceuticals Using Direct Solid Analysis- Electrothermal Vaporization Inductively Coupled Plasma Optical Emission Spectrometry
A solid sampling electrothermal vaporization inductively coupled plasma optical emission spectrometry (ETV-ICP OES) method for determination of As, Cd, Cr, Cu, Mn, Mo, Ni, Pb, Pd, Pt, Rh, Ru and V in pharmaceuticals is proposed. Tricyclic pharmaceuticals were directly analyzed due to their difficult decomposition with acids. Pyrolysis and vaporization temperature, sample mass, and reaction gas (Freon) flow rate were evaluated. The effect of organic and inorganic compounds was evaluated for matrix matching. The limits of detection ranged from 0.04 µg g−1 (Cu) to 107 µg g−1 (As) and the relative standard deviation was ...
Source: Journal of the Brazilian Chemical Society - April 1, 2015 Category: Chemistry Source Type: research
Medication Effects on Periurethral Sensation and Urethral Sphincter Activity
Conclusions: In women without lower urinary tract symptoms, pseudoephedrine improved urethral sensation but not urethral neuromuscular function on CNE or PFS. Imipramine, cyclobenzaprine, tamsulosin, solifenacin, and placebo did not change urethral sensation or neuromuscular function. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - February 25, 2015 Category: OBGYN Tags: Original Articles Source Type: research
Novel use of patch testing in the first report of allergic contact dermatitis to cyclobenzaprine.
PMID: 25581672 [PubMed - in process] (Source: Dermatitis)
Source: Dermatitis - January 1, 2015 Category: Dermatology Authors: Turrentine JE, Marrazzo G, Cruz PD Tags: Dermatitis Source Type: research
Partial to Complete Suppression of Unilateral Noise-Induced Tinnitus in Rats after Cyclobenzaprine Treatment
Abstract
Some forms of tinnitus are believed to arise from abnormal central nervous system activity following a single or repeated noise exposure, for which there are no widely accepted pharmacological treatments. One central site that could be related to tinnitus awareness or modulation is the locus coeruleus, a brainstem structure associated with stress, arousal, and attention. In the present study, we evaluated the effects of cyclobenzaprine, a drug known to act on the rat locus coeruleus, on noise-induced tinnitus using Gap Prepulse Inhibition of the Acoustic Startle (GPIAS). In untreated rats, brief ...
Source: JARO - Journal of the Association for Research in Otolaryngology - December 20, 2014 Category: ENT & OMF Source Type: research
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
CONCLUSION: The use of tizanidine or cyclobenzaprine in addition to self-care management and patient education was not more effective than placebo for the management of patients with myofascial jaw pain upon awakening.
PMID: 24822235 [PubMed - indexed for MEDLINE] (Source: Journal of Orofacial Pain)
Source: Journal of Orofacial Pain - November 25, 2014 Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
Rapid and sensitive analysis of cyclobenzaprine by LC–MS/MS: Application to a pharmacokinetic study of cyclobenzaprine in dog
Publication date: April 2014 Source:Asian Journal of Pharmaceutical Sciences, Volume 9, Issue 2 Author(s): Wenhong Yu , Xiaojing Yang , Wenwen Sui , Haiyan Xu , Xinyi Luan , Xiangjun Wang , Yi Jin , Bo Yuan A rapid and sensitive liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of cyclobenzaprine in dog plasma. After extracted with organic solvent, post-treatment samples were separated on an Agela C18 column interfaced with a triple quadrupole tandem mass spectrometer in positive electrospray ionization mode. Multiple reaction monitoring was performed usi...
Source: Asian Journal of Pharmaceutical Sciences - October 12, 2014 Category: Drugs & Pharmacology Source Type: research
Peripartum Pneumocephalus Associated With Epidural Anesthesia For Labor (P5.207)
Conclusions: Though thought to be rare, peripartum pneumocephalus may be more common than previously recognized and should be considered as an occasional etiology of headache following lumbar spinal/epidural anesthesia. Our patients with pneumocephalus had the defining characteristic of immediate and unilateral headache onset at catheter insertion.Disclosure: Dr. Reddi has nothing to disclose. Dr. Honchar has nothing to disclose. Dr. Robbins has received personal compensation for activities with Medlink. (Source: Neurology)
Source: Neurology - April 9, 2014 Category: Neurology Authors: Reddi, S., Honchar, V., Robbins, M. Tags: Headache: Epidemiology Source Type: research
Green Sweat: An Atypical Finding in Drug‐Induced Liver Disease
This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - December 24, 2013 Category: Gastroenterology Authors: Janaína Luz Narciso‐Schiavon, Gabriella Di Giunta, Mariana Horn André, Oscar Cardoso Dimatos, Esther Buzaglo Dantas‐Corrêa, Daniel Holthausen Nunes, Leonardo Lucca Schiavon Tags: Letter to the Editor Source Type: research
Rhabdomyolysis as a manifestation of clomipramine poisoning.
CONCLUSIONS: Although arrhythmia is the most important complication, rhabdomyolysis should be investigated in cases of clomipramine poisoning.
PMID: 24346784 [PubMed - in process] (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - December 23, 2013 Category: Journals (General) Authors: Santana NO, Góis AF Tags: Sao Paulo Med J Source Type: research
