Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review
We present the case of a 59-year old female with type 2 diabetes who complained of painful muscle spasms. Her muscle spasms involved in both feet, which have spread proximally to her legs. She also experienced intermittent muscle spasms in her left arm, which is not alleviated by baclofen, cyclobenzaprine. Her plasma pyridoxal 5-phosphate confirmed pyridoxine deficiency. Vitamins B1, B3, B12, and folate were within normal limits. The patient received standard-dose intramuscular pyridoxine injections for three weeks followed by oral supplements for 3 months and her symptoms resolved. This case illustrates the rare instance ...
Source: The American Journal of the Medical Sciences - May 7, 2021 Category: General Medicine Authors: Joseph Zhou Utibe Effiong Source Type: research
Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review
We present the case of a 59-year old female with type 2 diabetes who complained of painful muscle spasms. Her muscle spasms involved in both feet, which have spread proximally to her legs. She also experienced intermittent muscle spasms in her left arm, which is not alleviated by baclofen, cyclobenzaprine. Her plasma pyridoxal 5-phosphate confirmed pyridoxine deficiency. Vitamins B1, B3, B12, and folate were within normal limits. The patient received standard-dose intramuscular pyridoxine injections for three weeks followed by oral supplements for 3 months and her symptoms resolved. This case illustrates the rare instance ...
Source: The American Journal of the Medical Sciences - May 7, 2021 Category: General Medicine Authors: Joseph Zhou Utibe Effiong Source Type: research
Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review
We present the case of a 59-year old female with type 2 diabetes who complained of painful muscle spasms. Her muscle spasms involved in both feet, which have spread proximally to her legs. She also experienced intermittent muscle spasms in her left arm, which is not alleviated by baclofen, cyclobenzaprine. Her plasma pyridoxal 5-phosphate confirmed pyridoxine deficiency. Vitamins B1, B3, B12, and folate were within normal limits. The patient received standard-dose intramuscular pyridoxine injections for three weeks followed by oral supplements for 3 months and her symptoms resolved. This case illustrates the rare instance ...
Source: The American Journal of the Medical Sciences - May 7, 2021 Category: General Medicine Authors: Joseph Zhou Utibe Effiong Source Type: research
Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review
We present the case of a 59-year old female with type 2 diabetes who complained of painful muscle spasms. Her muscle spasms involved in both feet, which have spread proximally to her legs. She also experienced intermittent muscle spasms in her left arm, which is not alleviated by baclofen, cyclobenzaprine. Her plasma pyridoxal 5-phosphate confirmed pyridoxine deficiency. Vitamins B1, B3, B12, and folate were within normal limits. The patient received standard-dose intramuscular pyridoxine injections for three weeks followed by oral supplements for 3 months and her symptoms resolved. This case illustrates the rare instance ...
Source: The American Journal of the Medical Sciences - May 7, 2021 Category: General Medicine Authors: Joseph Zhou Utibe Effiong Source Type: research
Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review
We present the case of a 59-year old female with type 2 diabetes who complained of painful muscle spasms. Her muscle spasms involved in both feet, which have spread proximally to her legs. She also experienced intermittent muscle spasms in her left arm, which is not alleviated by baclofen, cyclobenzaprine. Her plasma pyridoxal 5-phosphate confirmed pyridoxine deficiency. Vitamins B1, B3, B12, and folate were within normal limits. The patient received standard-dose intramuscular pyridoxine injections for three weeks followed by oral supplements for 3 months and her symptoms resolved. This case illustrates the rare instance ...
Source: The American Journal of the Medical Sciences - May 7, 2021 Category: General Medicine Authors: Joseph Zhou Utibe Effiong Source Type: research
Exploring the Transmucosal Permeability of Cyclobenzaprine: A Comparative Preformulation by Standardized and Controlled Ex Vivo and In Vitro Permeation Studies
Publication date: Available online 5 April 2021Source: International Journal of PharmaceuticsAuthor(s): Haidara Majid, Andreas Puzik, Tanja Maier, Daniel Eberhard, Anke Bartel, Hans-Christian Mueller, Bjoern B. Burckhardt (Source: International Journal of Pharmaceutics)
Source: International Journal of Pharmaceutics - April 7, 2021 Category: Drugs & Pharmacology Source Type: research
Oral Muscle Relaxants for the Treatment of Chronic Pain Associated with Cerebral Palsy
Psychopharmacol Bull. 2020 Oct 15;50(4 Suppl 1):142-162.ABSTRACTPURPOSE OF REVIEW: This is a comprehensive literature review of the available for treatment of oral muscle relaxants for cerebral palsy (CP) and associated chronic pain. It briefly describes the background and etiology of pain in CP and proceeds to review and weigh the available evidence for treatment for muscle relaxants.RECENT FINDINGS: CP is a permanent, chronic, non-progressive neuromuscular and neurocognitive disorder of motor dysfunction that is diagnosed in infancy and is frequently (62% of patients) accompanied by chronic or recurrent muscular pain. Tr...
Source: Psychopharmacology Bulletin - February 26, 2021 Category: Psychiatry & Psychology Authors: Jacki Peck Ivan Urits Joshua Crane Alexandra McNally Nazir Noor Megha Patel Amnon A Berger Elyse M Cornett Hisham Kassem Alan D Kaye Omar Viswanath Source Type: research
