Rapid and sensitive analysis of cyclobenzaprine by LC–MS/MS: Application to a pharmacokinetic study of cyclobenzaprine in dog
Publication date: April 2014 Source:Asian Journal of Pharmaceutical Sciences, Volume 9, Issue 2 Author(s): Wenhong Yu , Xiaojing Yang , Wenwen Sui , Haiyan Xu , Xinyi Luan , Xiangjun Wang , Yi Jin , Bo Yuan A rapid and sensitive liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of cyclobenzaprine in dog plasma. After extracted with organic solvent, post-treatment samples were separated on an Agela C18 column interfaced with a triple quadrupole tandem mass spectrometer in positive electrospray ionization mode. Multiple reaction monitoring was performed usi...
Source: Asian Journal of Pharmaceutical Sciences - October 12, 2014 Category: Drugs & Pharmacology Source Type: research
Peripartum Pneumocephalus Associated With Epidural Anesthesia For Labor (P5.207)
Conclusions: Though thought to be rare, peripartum pneumocephalus may be more common than previously recognized and should be considered as an occasional etiology of headache following lumbar spinal/epidural anesthesia. Our patients with pneumocephalus had the defining characteristic of immediate and unilateral headache onset at catheter insertion.Disclosure: Dr. Reddi has nothing to disclose. Dr. Honchar has nothing to disclose. Dr. Robbins has received personal compensation for activities with Medlink. (Source: Neurology)
Source: Neurology - April 9, 2014 Category: Neurology Authors: Reddi, S., Honchar, V., Robbins, M. Tags: Headache: Epidemiology Source Type: research
Green Sweat: An Atypical Finding in Drug‐Induced Liver Disease
This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - December 24, 2013 Category: Gastroenterology Authors: Janaína Luz Narciso‐Schiavon, Gabriella Di Giunta, Mariana Horn André, Oscar Cardoso Dimatos, Esther Buzaglo Dantas‐Corrêa, Daniel Holthausen Nunes, Leonardo Lucca Schiavon Tags: Letter to the Editor Source Type: research
Rhabdomyolysis as a manifestation of clomipramine poisoning.
CONCLUSIONS: Although arrhythmia is the most important complication, rhabdomyolysis should be investigated in cases of clomipramine poisoning.
PMID: 24346784 [PubMed - in process] (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - December 23, 2013 Category: Journals (General) Authors: Santana NO, Góis AF Tags: Sao Paulo Med J Source Type: research
Risk of Injury Associated with Skeletal Muscle Relaxant Use in Older Adults (July/August).
CONCLUSIONS:Older adults using SMRs have an increased risk of injury. These findings provide evidence to support current recommendations to avoid the use of SMRs in elderly patients.
PMID: 23821610 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - July 2, 2013 Category: Drugs & Pharmacology Authors: Spence MM, Shin PJ, Lee EA, Gibbs NE Tags: Ann Pharmacother Source Type: research
Cyclobenzaprine: Drowsiness: case report
(Source: Reactions)
Source: Reactions - January 9, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
