Hepatocyte growth factor and risk of incident stroke in Black and White Americans in the Reasons for Geographic and Racial Differences in Stroke study
CONCLUSION: In the REGARDS study, higher HGF was associated with increased risk of incident ischemic stroke in Black and White adults, with a doubling in risk of HGF in the top quintile compared with the lowest quintile after adjusting for other stroke risk factors.PMID:38511198 | PMC:PMC10950816 | DOI:10.1016/j.rpth.2024.102340 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - March 21, 2024 Category: Hematology Authors: Sarah R Gillett Insu Koh Neil A Zakai Suzanne E Judd Timothy B Plante George Howard Mary Cushman Source Type: research

Paroxysmal nocturnal hemoglobinuria-related thrombosis in the era of novel therapies: a 2043 patient/years analysis
Blood. 2024 Mar 21:blood.2024023988. doi: 10.1182/blood.2024023988. Online ahead of print.ABSTRACTThrombophilia is one of the principal features of paroxysmal nocturnal hemoglobinuria (PNH) and constitutes the main cause of disease morbidity/mortality. Anti-complement treatment has revolutionized the natural history of PNH with control of the hemolytic process and abolition of thrombotic events (TE). However, no guidelines exist for the management of thromboembolic complications in this setting, with type and duration of anti-coagulation depending on individual practices. Besides, a scarcity of data is present on the effic...
Source: Cancer Control - March 21, 2024 Category: Cancer & Oncology Authors: Carmelo Gurnari Hussein Awada Simona Pagliuca Danai Dima Fauzia Ullah Naomi Kawashima Yasuo Kubota Ceylan Colak Valeria Visconte Bhumika J Patel Vikram Dhillon Naimisha Marneni Suresh Kumar Balasubramanian Ashwin Kishtagari Taha Bat Jaroslaw P Maciejewski Source Type: research

Assessment of temporary warfarin reversal in patients with left ventricular assist devices: the KVAD study
Due to advances in technology and limited availability of donor hearts, thousands of patients with advanced heart failure are supported with left ventricular assist devices (LVAD) either as a bridge-to-transplant, bridge-to-candidacy, or as destination therapy for those ineligible for a heart transplant.1 –3 The survival profile continues to improve, with 1 and 5 year survival rates of 83% and 52% respectively, allowing patients supported on these devices to live for longer periods of time.3–5 (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - March 21, 2024 Category: Cardiology Authors: Katelyn W. Sylvester, Jessica Grandoni, Megan Rhoten, Lara Coakley, Erin Matiello-Lyons, Katie Frankel, Brooke Fortin, Kate Jolley, Hae Soo Park, Revital Freedman, Mandeep R. Mehra, Michael M. Givertz, Jean M. Connors Source Type: research

The Quantitative Impact of Warfarin Versus Factor Xa Inhibitors on Anticoagulation Profiles in Patients With Peripheral Artery Disease Post-Revascularization
Anticoagulants are a mainstay of thromboembolic prevention in patients with cardiovascular disease, including peripheral artery disease (PAD). Newer factor Xa inhibitors are now being widely used in place of warfarin. There is a paucity of data regarding the impact of type of anticoagulant on coagulation parameters. The aim of this study was to quantify differences in coagulation parameters in patients taking warfarin versus factor Xa inhibitors. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Sasha Suarez Ferreira, Ryan Hall, Katherine Morrow, Shiv Patel, Ivy Lee, Fanah Hagos, Nikolaos Zacharias, Kellie Machlus, Anahita Dua Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
CONCLUSIONS: This study showed no significant difference in thrombus resolution between DOAC and warfarin. DOAC might be an alternative to warfarin for the treatment of LV thrombus. However, further large prospective studies are required to explore the efficacy and safety of DOAC in patients with LV thrombus.PMID:38505052 | PMC:PMC10944738 | DOI:10.21037/jtd-23-1582 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yang Zhou Xiaoxuan Zhang Yang Lin Wenxing Peng Source Type: research