The impact of child-specific characteristics on warfarin dosing requirements
CONCLUSION: The study confirmed that the patient demographics affect the daily warfarin dose required to achieve the INR target. However, they do not have any predictive value for the incidence of out-of-range-INR.PMID:38371334 | PMC:PMC10874749 | DOI:10.1016/j.rpth.2024.102321 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 19, 2024 Category: Hematology Authors: Yousif S Alakeel Abdulraouf M Z Jijeh Norah S BinSabbar Meshary F Almeshary Numan A Alabdan Jawaher A Gramish Mohammed A Al Essa Source Type: research
The impact of child-specific characteristics on warfarin dosing requirements
CONCLUSION: The study confirmed that the patient demographics affect the daily warfarin dose required to achieve the INR target. However, they do not have any predictive value for the incidence of out-of-range-INR.PMID:38371334 | PMC:PMC10874749 | DOI:10.1016/j.rpth.2024.102321 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - February 19, 2024 Category: Hematology Authors: Yousif S Alakeel Abdulraouf M Z Jijeh Norah S BinSabbar Meshary F Almeshary Numan A Alabdan Jawaher A Gramish Mohammed A Al Essa Source Type: research
A Facile Access to Green Fluorescent Albumin Derivatives
Chembiochem. 2024 Feb 18:e202300862. doi: 10.1002/cbic.202300862. Online ahead of print.ABSTRACTA Morita-Baylis-Hillman Adduct (MBHA) derivative bearing a triphenylamine moiety was found to react with human serum albumin (HSA) shifting its emission from the blue to the green-yellow thus leading to green fluorescent albumin (GFA) derivatives and enlarging the platform of probes for aggregation-induced fluorescent-based detection techniques. A possible interaction of MBHA derivative 7 with a lipophilic pocket within the HSA structure was suggested by docking studies. DLS experiments showed that the reaction with HSA induce a...
Source: Chembiochem - February 18, 2024 Category: Biochemistry Authors: Mario Saletti Marco Paolino Jacopo Venditti Claudia Bonechi Germano Giuliani Stefania Lamponi Giusy Tassone Antonella Boccia Chiara Botta Llu ís Blancafort Federica Poggialini Chiara Vagaggini Andrea Cappelli Source Type: research
Plasma: indications, controversies, and opportunities
Postgrad Med. 2024 Feb 16. doi: 10.1080/00325481.2024.2320080. Online ahead of print.ABSTRACTPlasma is overused as a blood product worldwide; however, data supporting appropriate use of plasma is scant. Its most common utilization is for treatment of coagulopathy in actively bleeding patients; it is also used for coagulation optimization prior to procedures with specific coagulation profile targets. A baseline literature review in PUBMED and Google Scholar was done (1 January 2000 to 1 June 2023), utilizing the following search terms: plasma, fresh frozen plasma, lyophilized plasma, indications, massive transfusion protoco...
Source: Postgraduate Medicine - February 16, 2024 Category: Internal Medicine Authors: Michael A Benson Deborah Tolich Jeannie L Callum Moises Auron Source Type: research
Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma
CONCLUSIONS: PKCδ is an enhanced biomarker for the diagnosis of HCC that compensates for the drawbacks of conventional markers.PMID:38361436 | DOI:10.1080/1354750X.2024.2312990 (Source: Biomarkers)
Source: Biomarkers - February 16, 2024 Category: Research Authors: Chika Nakagawa Tsunekazu Oikawa Kohji Yamada Akihito Tsubota Chisato Saeki Kuniko Katagiri Naoko Tago Hiroshi Kamioka Kaoru Ueda Koichiro Haruki Kenei Furukawa Masanori Nakano Yuichi Torisu Toru Ikegami Kiyotsugu Yoshida Masayuki Saruta Source Type: research
Plasma: indications, controversies, and opportunities
Postgrad Med. 2024 Feb 16. doi: 10.1080/00325481.2024.2320080. Online ahead of print.ABSTRACTPlasma is overused as a blood product worldwide; however, data supporting appropriate use of plasma is scant. Its most common utilization is for treatment of coagulopathy in actively bleeding patients; it is also used for coagulation optimization prior to procedures with specific coagulation profile targets. A baseline literature review in PUBMED and Google Scholar was done (1 January 2000 to 1 June 2023), utilizing the following search terms: plasma, fresh frozen plasma, lyophilized plasma, indications, massive transfusion protoco...
Source: Postgraduate Medicine - February 16, 2024 Category: Internal Medicine Authors: Michael A Benson Deborah Tolich Jeannie L Callum Moises Auron Source Type: research
Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma
CONCLUSIONS: PKCδ is an enhanced biomarker for the diagnosis of HCC that compensates for the drawbacks of conventional markers.PMID:38361436 | DOI:10.1080/1354750X.2024.2312990 (Source: Biomarkers)
Source: Biomarkers - February 16, 2024 Category: Research Authors: Chika Nakagawa Tsunekazu Oikawa Kohji Yamada Akihito Tsubota Chisato Saeki Kuniko Katagiri Naoko Tago Hiroshi Kamioka Kaoru Ueda Koichiro Haruki Kenei Furukawa Masanori Nakano Yuichi Torisu Toru Ikegami Kiyotsugu Yoshida Masayuki Saruta Source Type: research
Plasma: indications, controversies, and opportunities
Postgrad Med. 2024 Feb 16. doi: 10.1080/00325481.2024.2320080. Online ahead of print.ABSTRACTPlasma is overused as a blood product worldwide; however, data supporting appropriate use of plasma is scant. Its most common utilization is for treatment of coagulopathy in actively bleeding patients; it is also used for coagulation optimization prior to procedures with specific coagulation profile targets. A baseline literature review in PUBMED and Google Scholar was done (1 January 2000 to 1 June 2023), utilizing the following search terms: plasma, fresh frozen plasma, lyophilized plasma, indications, massive transfusion protoco...
Source: Postgraduate Medicine - February 16, 2024 Category: Internal Medicine Authors: Michael A Benson Deborah Tolich Jeannie L Callum Moises Auron Source Type: research
Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma
CONCLUSIONS: PKCδ is an enhanced biomarker for the diagnosis of HCC that compensates for the drawbacks of conventional markers.PMID:38361436 | DOI:10.1080/1354750X.2024.2312990 (Source: Biomarkers)
Source: Biomarkers - February 16, 2024 Category: Research Authors: Chika Nakagawa Tsunekazu Oikawa Kohji Yamada Akihito Tsubota Chisato Saeki Kuniko Katagiri Naoko Tago Hiroshi Kamioka Kaoru Ueda Koichiro Haruki Kenei Furukawa Masanori Nakano Yuichi Torisu Toru Ikegami Kiyotsugu Yoshida Masayuki Saruta Source Type: research
Plasma: indications, controversies, and opportunities
Postgrad Med. 2024 Feb 16. doi: 10.1080/00325481.2024.2320080. Online ahead of print.ABSTRACTPlasma is overused as a blood product worldwide; however, data supporting appropriate use of plasma is scant. Its most common utilization is for treatment of coagulopathy in actively bleeding patients; it is also used for coagulation optimization prior to procedures with specific coagulation profile targets. A baseline literature review in PUBMED and Google Scholar was done (1 January 2000 to 1 June 2023), utilizing the following search terms: plasma, fresh frozen plasma, lyophilized plasma, indications, massive transfusion protoco...
Source: Postgraduate Medicine - February 16, 2024 Category: Internal Medicine Authors: Michael A Benson Deborah Tolich Jeannie L Callum Moises Auron Source Type: research
Pregnancy outcomes in Chinese women with mechanical heart valves receiving warfarin treatment throughout pregnancy: 14-year experience
The purpose was to evaluate pregnancy outcomes and risk factors associated with fetal complications in Chinese pregnant women with mechanical heart valves (MHVs) taking low-dose warfarin, aiming to fill in the research gap of this area. (Source: Thrombosis Research)
Source: Thrombosis Research - February 15, 2024 Category: Hematology Authors: Tianyu Li, Lei Chen, Mei Peng, Guobao Song, Chunyan Wang, Qiyun Peng, Shenglan Tan Tags: Full Length Article Source Type: research
Effects of sodium ferulate for injection on anticoagulation of warfarin in rats in vivo
Herb-drug interactions may result in increased adverse drug reactions or diminished drug efficacy, especially for drugs with a narrow therapeutic index such as warfarin. The current study investigates the effe... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 14, 2024 Category: Complementary Medicine Authors: Yue Zhao, Chunjuan Yang, Yan Liu, Mengnan Qin, Jiahui Sun and Gaofeng Liu Tags: Research Source Type: research
