Safety Issues of Herb-Warfarin Interactions
Curr Drug Metab. 2024 Mar 8. doi: 10.2174/0113892002290846240228061506. Online ahead of print.ABSTRACTWarfarin is a popular anticoagulant with high global demand. However, studies have underlined serious safety issues when warfarin is consumed concomitantly with herbs or its formulations. This review aimed to highlight the mechanisms behind herb-warfarin interactions while laying special emphasis on its PKPD interactions and evidence on Herb-Warfarin Interaction (HWI) with regards to three different scenarios, such as when warfarin is consumed with herbs taken as foods or prescribed as medicine, or when used in special sit...
Source: Current Drug Metabolism - March 11, 2024 Category: Drugs & Pharmacology Authors: Subhajit Hazra Preet Amol Singh Neha Bajwa Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research

Evaluation of the Safety of Uninterrupted Warfarin Anticoagulation With Tranexamic Acid in Total Joint Arthroplasty
CONCLUSION: Many factors must be considered when choosing perioperative thromboembolic prophylaxis for arthroplasty candidates with medical comorbidities requiring long-term anticoagulation. This study presents data indicating that it could be safe and effective to continue therapeutic warfarin while using prophylactic TXA. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38466825 | DOI:10.3928/01477447-20240304-04 (Source: Orthopedics)
Source: Orthopedics - March 11, 2024 Category: Orthopaedics Authors: Michael G Johnston Matthew A Porter Kade E Eppich Celeste G Gray David F Scott Source Type: research