Occurrence and risk assessment of pharmaceuticals in hospital wastewater in Costa Rica
Chemosphere. 2023 Aug 5:139746. doi: 10.1016/j.chemosphere.2023.139746. Online ahead of print.ABSTRACTThis work aims to determine the occurrence, hazard and prioritization of pharmaceuticals from hospital wastewater in Costa Rica through the monitoring of 70 compounds and assessing their environmental risk through a hazard quotient approach (HQ). Moreover, the quantification of selected antibiotic resistance genes (ARGs) was conducted for the first time in this matrix in this geographical location. Thirty-four pharmaceuticals were detected, being caffeine, 1,7-dimethylxanthine, acetaminophen, ibuprofen, naproxen, ciproflox...
Source: Chemosphere - August 7, 2023 Category: Chemistry Authors: Carlos E Rodr íguez-Rodríguez Didier Ram írez-Morales Mario Masis-Mora Jos é R Montiel-Mora Claudio Soto-Garita Emanuel Araya-Valverde Juan Carlos Cambronero-Heinrichs Alexandre S ànchez-Melsió Susana Brice ño-Guevara Michael Mendez-Rivera Jos é L Source Type: research

Occurrence and risk assessment of pharmaceuticals in hospital wastewater in Costa Rica
Chemosphere. 2023 Aug 5:139746. doi: 10.1016/j.chemosphere.2023.139746. Online ahead of print.ABSTRACTThis work aims to determine the occurrence, hazard and prioritization of pharmaceuticals from hospital wastewater in Costa Rica through the monitoring of 70 compounds and assessing their environmental risk through a hazard quotient approach (HQ). Moreover, the quantification of selected antibiotic resistance genes (ARGs) was conducted for the first time in this matrix in this geographical location. Thirty-four pharmaceuticals were detected, being caffeine, 1,7-dimethylxanthine, acetaminophen, ibuprofen, naproxen, ciproflox...
Source: Chemosphere - August 7, 2023 Category: Chemistry Authors: Carlos E Rodr íguez-Rodríguez Didier Ram írez-Morales Mario Masis-Mora Jos é R Montiel-Mora Claudio Soto-Garita Emanuel Araya-Valverde Juan Carlos Cambronero-Heinrichs Alexandre S ànchez-Melsió Susana Brice ño-Guevara Michael Mendez-Rivera Jos é L Source Type: research

Experimental infection of < i > Artibeus lituratus < /i > bats and no detection of Zika virus in neotropical bats from French Guiana, Peru, and Costa Rica suggests a limited role of bats in Zika transmission
by Alvaro Aguilar-Seti én, Mónica Salas-Rojas, Guillermo Gálvez-Romero, Cenia Almazán-Marín, Andrés Moreira-Soto, Jorge Alfonso-Toledo, Cirani Obregón-Morales, Martha García-Flores, Anahí García-Baltazar, Jordi Serra-Cobo, Marc López-Roig, Nora Reyes-Puma, Marta Piche-Ovares, Mario Romero-Vega, Daniel Felipe Ba rrantes Murillo, Claudio Soto-Garita, Alejandro Alfaro-Alarcón, Eugenia Corrales-Aguilar, Osvaldo López-Díaz, Dominique Pontier, Ondine Filippi-Codaccioni, Jean-Baptiste Pons, Jeanne Duhayer, Jan Felix Drexler Bats are important natural reservoir hosts of a diverse range of viruses that can be transmi...
Source: PLoS Neglected Tropical Diseases - July 24, 2023 Category: Tropical Medicine Authors: Alvaro Aguilar-Seti én Source Type: research

Assessing heavy metal pollution load index (PLI) in biomonitors and road dust from vehicular emission by magnetic properties modeling
This study aimed to assess the HM pollution load in biomonitors and road dust from vehicular emissions by chemical analyses and magnetic properties modeling. For this purpose, chemical and magnetic property analyses were carried out on samples of road dust and leaves of Cupressus lusitanica Mill. and Casuarina equisetifolia L., which were sampled during 2 different years in the Greater Metropolitan Area of Costa Rica known as GAM. Contamination factor (CF) and pollution load index (PLI) results showed significant metal pollution in some of the study sites. Contamination by the metals V, Cr, and Zn was most commonly present...
Source: Environmental Science and Pollution Research International - July 20, 2023 Category: Environmental Health Authors: Teresa Salazar-Rojas Fredy Rub én Cejudo-Ruiz Marco V Guti érrez-Soto Guillermo Calvo-Brenes Source Type: research

Detection of the fungicide transformation product 4-hydroxychlorothalonil in serum of pregnant women from Sweden and Costa Rica
Journal of Exposure Science & Environmental Epidemiology, Published online: 20 July 2023; doi:10.1038/s41370-023-00580-8Detection of the fungicide transformation product 4-hydroxychlorothalonil in serum of pregnant women from Sweden and Costa Rica (Source: Journal of Exposure Science and Environmental Epidemiology)
Source: Journal of Exposure Science and Environmental Epidemiology - July 20, 2023 Category: Epidemiology Authors: Annette M. Krais Berna van Wendel de Joode Emelie Rietz Liljedahl Annelise J. Blomberg Anna R önnholm Marie Bengtsson Juan Camilo Cano Jane A. Hoppin Margareta Littorin Christel Nielsen Christian H. Lindh Source Type: research

Comparison among three predictive models for cancer-associated thromboembolism in a hispanic population
In this study we aimed to evaluate and compare the overall performance of the Khorana, PROTECHT, and CONKO scores as predictive scores for the occurrence of venous thromboembolism (VTE) among ambulatory Hispanic patients with solid tumors. We included all outpatients with newly diagnosed solid tumors receiving systemic chemotherapy in Hospital San Juan Dios, San Jos é, Costa Rica, from January to December 2021. For each patient the Khorana, PROTECHT, and CONKO scores were calculated at the beginning of treatment. The sixth-month cumulative incidence of VTE was estimated using the Fine& Gray competing risk model. The r...
Source: Journal of Thrombosis and Thrombolysis - July 6, 2023 Category: Hematology Source Type: research

Exploring Handgrip Strength as a Cross-cultural Correlate of Body Composition and Upper Body Strength in Older Adults from Costa Rica and Kansas
This study compared HGS to multiple measurements of body composition in older adults from the US (Kansas) and a middle-income country (Costa Rica) to test if HGS is a cross-culturally appropriate predictive measure that yields reliable estimates across developed and developing nations. Percent body fat (%BF), lean tissue mass index (LTMI), appendicular lean soft tissue index (ALSTI), body fat mass index (BFMI), bone mineral density (BMD), and HGS were measured in older Costa Ricans (n  = 78) and Kansans (n = 100). HGS predicted lean arm mass with equal accuracy for both samples (p ≤ 0.05 for all groups), indi...
Source: Journal of Cross-Cultural Gerontology - July 6, 2023 Category: Geriatrics Source Type: research

Thermal desorption direct analysis in real ‐time high‐resolution mass spectrometry and machine learning allow the rapid authentication of ground black pepper and dried oregano: A proof‐of‐concept study
In this study, TD-DART-HRMS's utility for establishing spice authenticity was examined. To this aim, we directly analyzed authentic (typical) and adulterated (atypical) samples of ground black pepper and dried oregano in positive and negative ion modes. We analyzed a set of authentic ground black pepper samples (n = 14) originating from Brazil, Sri Lanka, Madagascar, Ecuador, Vietnam, Costa Rica, Indonesia, Cambodia, and adulterated samples (n = 25) consisting of mixtures of ground black pepper with this spice's nonfunctional by-products (pinheads or spent) or with different exogenous materials (olive kernel, green...
Source: Journal of Mass Spectrometry - July 4, 2023 Category: Chemistry Authors: Carmela Zacometti, Andrea Massaro, Tommaso Gioia, Stephane Lefevre, Aline Fr égière‐Salomon, Jean‐Louis Lafeuille, Ingrid Fiordaliso Candalino, Michele Suman, Roberto Piro, Alessandra Tata Tags: RESEARCH ARTICLE Source Type: research

A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and childreUMn from the ISA birth cohort, Costa Rica
CONCLUSION: Rhinitis and wheeze were associated with elevated FeNO in this rural, agricultural population. Smoke from waste burning as well as para-occupational pesticide exposure may contribute to elevated FeNO in rural communities.PMID:37356534 | DOI:10.1016/j.envres.2023.116449 (Source: Environmental Research)
Source: Environmental Research - June 25, 2023 Category: Environmental Health Authors: Derek Werthmann Berna van Wendel de Joode Michael T Cuffney Brian J Reich Manuel E Soto-Martinez Andrea Corrales-Vargas Luis Palomo-Cordero Jorge Pe ñaloza-Castañeda Jane A Hoppin Source Type: research

New tobacco and nicotine products in Latin America and the Caribbean: assessing the market and regulatory environment
Conclusion NTNPs are emerging products in the LAC region. Governments should follow WHO guidance and the decisions of the Conference of Parties to the WHO Framework Convention on Tobacco Control and ban or regulate NTNPs as tobacco products; otherwise NTNPs could create a new generation of tobacco and nicotine users. (Source: Tobacco Control)
Source: Tobacco Control - June 20, 2023 Category: Respiratory Medicine Authors: Crosbie, E., Severini, G., Beem, A., Tran, B., Sebrie, E. M. Tags: Original research Source Type: research

Viruses, Vol. 15, Pages 1390: Two Decades of Wildlife Pathogen Surveillance: Case Study of Choclo orthohantavirus and Its Wild Reservoir Oligoryzomys costaricensis
Armien Joseph A. Cook Blas Armien The Costa Rican pygmy rice rat (Oligoryzomys costaricensis) is the primary reservoir of Choclo orthohantavirus (CHOV), the causal agent of hantavirus disease, pulmonary syndrome, and fever in humans in Panama. Since the emergence of CHOV in early 2000, we have systematically sampled and archived rodents from &amp;gt;150 sites across Panama to establish a baseline understanding of the host and virus, producing a permanent archive of holistic specimens that we are now probing in greater detail. We summarize these collections and explore preliminary habitat/virus associations to ...
Source: Viruses - June 17, 2023 Category: Virology Authors: Publio Gonzalez Jacqueline R. Salazar Tybbysay P. Salinas Mario Avila Jocelyn P. Colella Jonathan L. Dunnum Gregory E. Glass Gloria Gonzalez Enos Juarez Kimberly Lindblade Edwin Pile Yaxelis Mendoza Juan Miguel Pascale Anibal G. Armien Joseph A. Cook Blas Tags: Article Source Type: research

Bothrops asper bite and post-traumatic stress disorder in Costa Rica: Report of two cases
Toxicon. 2023 Jun 14:107199. doi: 10.1016/j.toxicon.2023.107199. Online ahead of print.ABSTRACTSnakebite envenoming (SBE) is a public health problem of high impact worldwide. The psychiatric consequences of SBE have been poorly documented. Here we present in detail the phenomenology of two clinical cases of Bothrops asper snakebite post-traumatic stress disorder (SBPTSD) in Costa Rica. We suggest that there is a characteristic presentation of SBPTSD and hypothesize that main contributors to the development of this disorder are: the systemic inflammatory response, the repetition of events that put the patient's life at risk...
Source: Toxicon - June 16, 2023 Category: Toxicology Authors: Ricardo Mill án-González Luis F Monge-Morales Natalia De La Cruz-Villalobos Fabi án Bonilla-Murillo Jos é María Gutiérrez Source Type: research

Bothrops asper bite and post-traumatic stress disorder in Costa Rica: Report of two cases
Toxicon. 2023 Jun 14:107199. doi: 10.1016/j.toxicon.2023.107199. Online ahead of print.ABSTRACTSnakebite envenoming (SBE) is a public health problem of high impact worldwide. The psychiatric consequences of SBE have been poorly documented. Here we present in detail the phenomenology of two clinical cases of Bothrops asper snakebite post-traumatic stress disorder (SBPTSD) in Costa Rica. We suggest that there is a characteristic presentation of SBPTSD and hypothesize that main contributors to the development of this disorder are: the systemic inflammatory response, the repetition of events that put the patient's life at risk...
Source: Toxicon - June 16, 2023 Category: Toxicology Authors: Ricardo Mill án-González Luis F Monge-Morales Natalia De La Cruz-Villalobos Fabi án Bonilla-Murillo Jos é María Gutiérrez Source Type: research

Bothrops asper bite and post-traumatic stress disorder in Costa Rica: Report of two cases
Toxicon. 2023 Jun 14;231:107199. doi: 10.1016/j.toxicon.2023.107199. Online ahead of print.ABSTRACTSnakebite envenoming (SBE) is a public health problem of high impact worldwide. The psychiatric consequences of SBE have been poorly documented. Here we present in detail the phenomenology of two clinical cases of Bothrops asper snakebite post-traumatic stress disorder (SBPTSD) in Costa Rica. We suggest that there is a characteristic presentation of SBPTSD and hypothesize that main contributors to the development of this disorder are: the systemic inflammatory response, the repetition of events that put the patient's life at ...
Source: Toxicon - June 16, 2023 Category: Toxicology Authors: Ricardo Mill án-González Luis F Monge-Morales Natalia De La Cruz-Villalobos Fabi án Bonilla-Murillo Jos é María Gutiérrez Source Type: research