Ultrahigh-precision noble gas isotope analyses reveal pervasive subsurface fractionation in hydrothermal systems
Sci Adv. 2023 Apr 14;9(15):eadg2566. doi: 10.1126/sciadv.adg2566. Epub 2023 Apr 14.ABSTRACTMantle-derived noble gases in volcanic gases are powerful tracers of terrestrial volatile evolution, as they contain mixtures of both primordial (from Earth's accretion) and secondary (e.g., radiogenic) isotope signals that characterize the composition of deep Earth. However, volcanic gases emitted through subaerial hydrothermal systems also contain contributions from shallow reservoirs (groundwater, crust, atmosphere). Deconvolving deep and shallow source signals is critical for robust interpretations of mantle-derived signals. Here...
Source: Adv Data - April 14, 2023 Category: Epidemiology Authors: David V Bekaert Peter H Barry Michael W Broadley David J Byrne Bernard Marty Carlos J Ram írez J Maarten de Moor Alejandro Rodriguez Michael R Hudak Adam V Subhas Saemundur A Halld órsson Andri Stef ánsson Antonio Caracausi Karen G Lloyd Donato Giovann Source Type: research

A novel interdomain consortium from a Costa Rican oil well composed of Methanobacterium  cahuitense sp. nov. and Desulfomicrobium aggregans sp. nov
Arch Microbiol. 2023 Apr 13;205(5):189. doi: 10.1007/s00203-023-03533-9.ABSTRACTA novel interdomain consortium composed of a methanogenic Archaeon and a sulfate-reducing bacterium was isolated from a microbial biofilm in an oil well in Cahuita National Park, Costa Rica. Both organisms can be grown in pure culture or as stable co-culture. The methanogenic cells were non-motile rods producing CH4 exclusively from H2/CO2. Cells of the sulfate-reducing partner were motile rods forming cell aggregates. They utilized hydrogen, lactate, formate, and pyruvate as electron donors. Electron acceptors were sulfate, thiosulfate, and su...
Source: Archives of Microbiology - April 13, 2023 Category: Microbiology Authors: Linda Dengler Julia Meier Andreas Klingl Laura Ni ßl Annett Bellack Dina Grohmann Reinhard Rachel Harald Huber Source Type: research

A novel interdomain consortium from a Costa Rican oil well composed of Methanobacterium  cahuitense sp. nov. and Desulfomicrobium aggregans sp. nov
Arch Microbiol. 2023 Apr 13;205(5):189. doi: 10.1007/s00203-023-03533-9.ABSTRACTA novel interdomain consortium composed of a methanogenic Archaeon and a sulfate-reducing bacterium was isolated from a microbial biofilm in an oil well in Cahuita National Park, Costa Rica. Both organisms can be grown in pure culture or as stable co-culture. The methanogenic cells were non-motile rods producing CH4 exclusively from H2/CO2. Cells of the sulfate-reducing partner were motile rods forming cell aggregates. They utilized hydrogen, lactate, formate, and pyruvate as electron donors. Electron acceptors were sulfate, thiosulfate, and su...
Source: Archives of Microbiology - April 13, 2023 Category: Microbiology Authors: Linda Dengler Julia Meier Andreas Klingl Laura Ni ßl Annett Bellack Dina Grohmann Reinhard Rachel Harald Huber Source Type: research

Estimating human papillomavirus vaccine efficacy from a single-arm trial: Proof-of-principle in the Costa Rica Vaccine Trial
CONCLUSION: We demonstrate that a single-arm design yields valid VE estimates with similar precision to an RCT. Single-arm studies can reduce the sample size and costs of future HPV vaccine trials while avoiding concerns related to unvaccinated control groups.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT00128661.PMID:37040086 | DOI:10.1093/jnci/djad064 (Source: Cancer Control)
Source: Cancer Control - April 11, 2023 Category: Cancer & Oncology Authors: Brian Befano Nicole G Campos Didem Egemen Rolando Herrero Mark Schiffman Carolina Porras Douglas R Lowy Ana Cecilia Rodriguez John T Schiller Rebecca Ocampo Allan Hildesheim Joshua N Sampson Shrutikona Das Aim ée R Kreimer Li C Cheung Costa Rica HPV Vacc Source Type: research

Pesticide use in banana plantations in Costa Rica - A review of environmental and human exposure, effects and potential risks
Environ Int. 2023 Mar 17;174:107877. doi: 10.1016/j.envint.2023.107877. Online ahead of print.ABSTRACTBiodiversity is declining on a global scale. Especially tropical ecosystems, containing most of the planetary biodiversity, are at risk. Agricultural monocrop systems contribute to this decline as they replace original habitats and depend on extensive use of synthetic pesticides that impact ecosystems. In this review we use large-scale banana production for export purposes in Costa Rica as an example for pesticide impacts, as it is in production for over a century and uses pesticides extensively for more than fifty years. ...
Source: Environment International - April 8, 2023 Category: Environmental Health Authors: Carsten A Br ühl Maria Arias Andres Silvia Echeverr ía-Sáenz Mirco Bundschuh Anja Kn äbel Freylan Mena Lara L Petschick Clemens Ruepert Sebastian Stehle Source Type: research

Pesticide use in banana plantations in Costa Rica - A review of environmental and human exposure, effects and potential risks
Environ Int. 2023 Mar 17;174:107877. doi: 10.1016/j.envint.2023.107877. Online ahead of print.ABSTRACTBiodiversity is declining on a global scale. Especially tropical ecosystems, containing most of the planetary biodiversity, are at risk. Agricultural monocrop systems contribute to this decline as they replace original habitats and depend on extensive use of synthetic pesticides that impact ecosystems. In this review we use large-scale banana production for export purposes in Costa Rica as an example for pesticide impacts, as it is in production for over a century and uses pesticides extensively for more than fifty years. ...
Source: Environment International - April 8, 2023 Category: Environmental Health Authors: Carsten A Br ühl Maria Arias Andres Silvia Echeverr ía-Sáenz Mirco Bundschuh Anja Kn äbel Freylan Mena Lara L Petschick Clemens Ruepert Sebastian Stehle Source Type: research

Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: an analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru
Our study analyzes the cost-effectiveness of the COVID-19 vaccination campaigns in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. (Source: Cost Effectiveness and Resource Allocation)
Source: Cost Effectiveness and Resource Allocation - April 1, 2023 Category: Health Management Authors: Augustovski Federico, Bardach Ariel, Santoro Adri án, Rodriguez-Cairoli Federico, López-Osornio Alejandro, Argento Fernando, Havela Maissa, Blumenfeld Alejandro, Ballivian Jamile, Solioz Germán, Capula Analía, López Analía, Cejas Cintia, Savedoff Wi Tags: Research Source Type: research

Frequencies of variants in genes associated with dyslipidemias identified in Costa Rican genomes
Dyslipidemias are risk factors in diseases of significant importance to public health, such as atherosclerosis, a condition that contributes to the development of cardiovascular disease. Unhealthy lifestyles, the pre-existence of diseases, and the accumulation of genetic variants in some loci contribute to the development of dyslipidemia. The genetic causality behind these diseases has been studied primarily on populations with extensive European ancestry. Only some studies have explored this topic in Costa Rica, and none have focused on identifying variants that can alter blood lipid levels and quantifying their frequency...
Source: Frontiers in Genetics - March 30, 2023 Category: Genetics & Stem Cells Source Type: research

Molecules, Vol. 28, Pages 2910: Chemical Composition, Enantiomeric Distribution and Biological Activity of Essential Oil from Morella pubescens (Humb. & amp; Bonpl. ex Willd.) Wilbur
In this study, the chemical composition, enantiomeric distribution, and biological activity of essential oil isolated from the leaves of this species was determined. Hydrodistillation was used to isolate the essential oil (EO). Gas chromatography coupled with mass spectrometry was used to determine the qualitative composition, gas chromatography equipped with a flame ionization detector was used to determine quantitative composition, and gas chromatography on an enantioselective column was used to determine enantiomeric distribution. The broth microdilution method was employed to assess the antibacterial capacity of the es...
Source: Molecules - March 24, 2023 Category: Chemistry Authors: Eduardo Valarezo Carlos Correa-Jaramillo Paola Astudillo-D ávila Julio Garz ón-Yaguache Luis Cartuche Miguel Angel Meneses Vladimir Morocho Tags: Article Source Type: research

A potential consequence for urban birds' fitness: Exposed anthropogenic nest materials reduce nest survival in the clay-colored thrush
Environ Pollut. 2023 Mar 18:121456. doi: 10.1016/j.envpol.2023.121456. Online ahead of print.ABSTRACTUrban bird dwellers survive and reproduce in highly urbanized ecosystems. Some individuals adjust to these novel conditions by changing natural nesting materials for artificial materials, thus making nests more conspicuous in the environment. The consequences of using artificial materials for nesting remain poorly understood, especially from a nest-predator perspective. We studied if exposed artificial materials on bird nests affect the daily survival rate in a common dweller species, the clay-colored thrush (Turdus grayi)....
Source: Environmental Pollution - March 20, 2023 Category: Environmental Health Authors: Josu é Corrales-Moya Gilbert Barrantes Eduardo Chac ón-Madrigal Luis Sandoval Source Type: research

A potential consequence for urban birds' fitness: Exposed anthropogenic nest materials reduce nest survival in the clay-colored thrush
Environ Pollut. 2023 Mar 18:121456. doi: 10.1016/j.envpol.2023.121456. Online ahead of print.ABSTRACTUrban bird dwellers survive and reproduce in highly urbanized ecosystems. Some individuals adjust to these novel conditions by changing natural nesting materials for artificial materials, thus making nests more conspicuous in the environment. The consequences of using artificial materials for nesting remain poorly understood, especially from a nest-predator perspective. We studied if exposed artificial materials on bird nests affect the daily survival rate in a common dweller species, the clay-colored thrush (Turdus grayi)....
Source: Environmental Pollution - March 20, 2023 Category: Environmental Health Authors: Josu é Corrales-Moya Gilbert Barrantes Eduardo Chac ón-Madrigal Luis Sandoval Source Type: research

A potential consequence for urban birds' fitness: Exposed anthropogenic nest materials reduce nest survival in the clay-colored thrush
Environ Pollut. 2023 Mar 18:121456. doi: 10.1016/j.envpol.2023.121456. Online ahead of print.ABSTRACTUrban bird dwellers survive and reproduce in highly urbanized ecosystems. Some individuals adjust to these novel conditions by changing natural nesting materials for artificial materials, thus making nests more conspicuous in the environment. The consequences of using artificial materials for nesting remain poorly understood, especially from a nest-predator perspective. We studied if exposed artificial materials on bird nests affect the daily survival rate in a common dweller species, the clay-colored thrush (Turdus grayi)....
Source: Environmental Pollution - March 20, 2023 Category: Environmental Health Authors: Josu é Corrales-Moya Gilbert Barrantes Eduardo Chac ón-Madrigal Luis Sandoval Source Type: research

Genotypes and morphologies of bovine papillomaviruses in Costa Rica
AbstractBovine papillomaviruses (BPVs) infect the basal layer of the epithelium of bovines, where they persist asymptomatically or produce benign fibroepithelial hyperplasia in the skin or mucosa. The aim of the present study was to describe the genotypes of bovine papillomas at the macroscopic and microscopic level. A descriptive study was carried out using non-probabilistic convenience sampling. Ninety-nine papillomas from 63 animals were collected on 32 farms, as well as information about age, gender, breed, and productive use of the bovines. The location, type, and degree of epithelial invasion of the papillomas were r...
Source: Archives of Virology - March 16, 2023 Category: Virology Source Type: research

Molecules, Vol. 28, Pages 2665: Profiling and Quantification of Anthocyanins in Purple-Pericarp Sweetcorn and Purple-Pericarp Maize
Hare Purple-pericarp sweetcorn accessions, derived from crossing purple-pericarp maize with white shrunken2 sweetcorn, were assessed for differences in anthocyanin profile at both sweetcorn eating stage and at full kernel maturity. The ‘Tim1’ sweetcorn line developed a similar total anthocyanin concentration to its ‘Costa Rica’ parent when assessed at sweetcorn-eating stage. At full maturity it surpassed the purple maize parent, but this was mainly due to the presence of starch diluting the anthocyanin concentration of the latter. The anthocyanin/colour relationsh...
Source: Molecules - March 15, 2023 Category: Chemistry Authors: Apurba Anirban Hung T. Hong Tim J. O ’Hare Tags: Article Source Type: research

Multiple endocrine neoplasia type 1 familial case in a patient with insulinoma and primary hyperparathyroidism: First report in literature and in the Costa Rican population of the c.1224_1225insGTCC pathogenic variant
This report of a MEN1 family in Costa Rica with a novel MEN1-pathogenic variant underlines that a thorough analysis may lead to new mutations description, impacts gene biology knowledge, patient follow-up, and population's genetic characteristics. AbstractMultiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder without a good genotype –phenotype correlation, characterized by tumor predisposition in the parathyroid gland, anterior pituitary, and pancreatic islet cells. Here, we describe a 37-year-old male with previous history of nephrolithiasis, with a 1-year history of recurrent hypoglycemic epis...
Source: Clinical Case Reports - March 8, 2023 Category: General Medicine Authors: Paula Molina ‐Céspedes, Ernesto José Ruiz‐Golcher, Oscar Badilla‐Barboza, Giovanni Sedó‐Mejía, Laura Barboza‐Rodríguez, Ramsés Badilla‐Porras Tags: CASE REPORT Source Type: research