Association between lipoprotein(a) and cardiovascular disease in patients undergoing coronary angiography
CONCLUSION: The findings indicated that elevated lipoprotein(a) had no obvious relationship with hypertension and obesity. Elevated lipoprotein(a) increases the risk of high total cholesterol, high LDL‑c, and premature CAD, and increases the occurrence and severity of coronary heart disease.PMID:38658408 | DOI:10.1007/s00059-024-05247-0 (Source: Herz)
Source: Herz - April 24, 2024 Category: Cardiology Authors: Azhi ShaMa Chunmei Xu Yingying Huang Chunlan Ma Jingyue Hu Zhuxin Li Chunyu Zeng Source Type: research
The Association of CHADS-P2A2RC Risk Score With Clinical Outcomes in Patients Taking P2Y12 Inhibitor Monotherapy After 3 Months of Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention
CONCLUSIONS: The CHADS-P2A2RC risk score is valuable in discriminating high-ischemic-risk patients. Even in such patients with a high risk of ischemic events, P2Y12 inhibitor monotherapy was associated with a lower incidence of bleeding without increased risk of ischemic events compared with prolonged DAPT.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02079194.PMID:38654565 | PMC:PMC11040264 | DOI:10.4070/kcj.2023.0268 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Pil Sang Song Seok-Woo Seong Ji-Yeon Kim Soo Yeon An Mi Joo Kim Kye Taek Ahn Seon-Ah Jin Jin-Ok Jeong Jeong Hoon Yang Joo-Yong Hahn Hyeon-Cheol Gwon Woo Jin Jang Hyuck Jun Yoon Jang-Whan Bae Woong Gil Choi Young Bin Song Source Type: research
Microvascular resistance reserve before and after PCI: a serial FFR and [15O] H2O PET study
Microvascular Resistance Reserve (MRR) has recently been introduced as a microvasculature-specific index and hypothesized to be independent of coronary stenosis. The aim of this study was to investigate the change of MRR after percutaneous coronary intervention (PCI). (Source: Atherosclerosis)
Source: Atherosclerosis - April 24, 2024 Category: Cardiology Authors: Masahiro Hoshino, Ruurt.A. Jukema, Nico Pijls, Roel Hoek, Pieter Raijmakers, Roel Driessen, Pepijn van Diemen, Jos Twisk, Tim van der Hoef, Ibrahim Danad, Tsunekazu Kakuta, Paul Knaapen Source Type: research
An audit of patient radiation doses during interventional cardiology procedures in Uttarakhand, India, and establishment of local diagnostic reference levels
The objective of this study was to investigate patient radiation doses by a dose audit of three common interventional cardiology (IC) procedures: coronary angiography (CA), percutaneous transluminal coronary angioplasty (PTCA) and CA –PTCA procedures performed in IC centres in the Uttarakhand state of India, for the establishment of local diagnostic reference levels (DRLs) and the estimation of average effective dose (Eav) for these procedures. For each procedure, the values of kerma-area product (PKA), reference air kerma (Ka,r), fluoroscopy time (FT) and the number of cine images were recorded from 1233 CA, 458 PTCA an...
Source: Radiological Physics and Technology - April 23, 2024 Category: Physics Source Type: research
A case report of ventricular fibrillation following Shockwave intravascular lithotripsy during percutaneous coronary intervention
Shockwave intravascular lithotripsy (S-IVL) is widely used during percutaneous coronary intervention (PCI) of calcified coronary arteries. Ventricular capture beats during S-IVL are common but arrhythmias are ... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 23, 2024 Category: Cardiology Authors: Lars Jakobsen, Evald H øj Christiansen and Troels Thim Tags: Case Report Source Type: research
A case of coronary artery compression syndrome resulting from peri-valvular regurgitation and long-standing atrial fibrillation
J Cardiol Cases. 2024 Jan 6;29(4):157-160. doi: 10.1016/j.jccase.2023.12.003. eCollection 2024 Apr.ABSTRACTA man in his 70s with a history of mitral valve replacement (MVR) and long-standing persistent atrial fibrillation (AF) presented with effort angina. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA). As it was an emergent case, PCI (percutaneous coronary intervention) was selected for treatment. Intravascular ultrasonography revealed no atherosclerotic lesions in the LMCA. The LMCA was effectively dilated by the drug-eluting stent. No elevation in intracardiac pressure was observed...
Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: Keisuke Suzuki Yoshiaki Mibiki Mai Suzuki Hiroshi Nakagata Kosuke Aoki Eiji Sato Yoshihiro Yamashina Takehiko Miyashita Akihiko Ishida Tetsuo Yagi Source Type: research
Sex-based Differences in Complex Percutaneous Coronary Intervention - Insights from COMPLEX Registry
Hellenic J Cardiol. 2024 Apr 20:S1109-9666(24)00080-0. doi: 10.1016/j.hjc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38648939 | DOI:10.1016/j.hjc.2024.04.005 (Source: Hellenic Journal of Cardiology)
Source: Hellenic Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Sylwia Iwa ńczyk Samir Ahmad Dit Al Hakim Marta Skrzypi ńska Zofia Stanisz Patrycja Wo źniak Weronika Go ściniak Aleksander Araszkiewicz Fatima Al Salman Ali Hok Marwan Mhanna Wiktoria Chylinska W łodzimierz Skorupski Micha ł Lesiak Marek Grygier Ma Source Type: research
Acute coronary syndrome in patients treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants: Proposed management algorithm for the first 48hours
Arch Cardiovasc Dis. 2024 Apr 12:S1875-2136(24)00058-5. doi: 10.1016/j.acvd.2024.02.012. Online ahead of print.ABSTRACTAround 10% of patients with acute coronary syndrome are treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants for various indications. The initial management of these patients is highly complex, and new guidelines specify that, only during percutaneous coronary intervention, a bolus of unfractionated heparin is recommended in one of the following circumstances: (1) if the patient is receiving a non-vitamin K antagonist oral anticoagulant; or (2) if the international normalized ra...
Source: Archives of Cardiovascular Diseases - April 21, 2024 Category: Cardiology Authors: Alexandre Salaun Emmanuel de Maistre Marl ène Daller Chan Sombrun Fr édéric Chagué Florence Bichat Luc Rochette Nicolas Danchin Laurent Fauchier Marianne Zeller Yves Cottin Source Type: research
Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels via VEGF Signaling Pathway Activation by miRNA-126
In this study, we clarified the mechanism by which Detoxification and Activating Blood Circulation Decoction (DABCD) promotes vascular reendothelialization to avoid ISR by miRNA-126-mediated modulation of the vascular endothelial growth factor (VEGF) signaling pathway. A rat model of post-PCI restenosis was established by balloon injury. The injured aortic segment was collected 14 and 28 d after model establishment. Our findings indicate that on the 14th and 28th days following balloon injury, DABCD reduced intimal hyperplasia and inflammation and promoted vascular reendothelialization. Additionally, DABCD markedly increas...
Source: Biological and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhiming Liu Guangmie Xie Zuwei Li Hanbin Luo Jianhong Zhou Jie Cheng Xiaolin Wang Xiaoyan Huang Guohui Zou Source Type: research
Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels via VEGF Signaling Pathway Activation by miRNA-126
In this study, we clarified the mechanism by which Detoxification and Activating Blood Circulation Decoction (DABCD) promotes vascular reendothelialization to avoid ISR by miRNA-126-mediated modulation of the vascular endothelial growth factor (VEGF) signaling pathway. A rat model of post-PCI restenosis was established by balloon injury. The injured aortic segment was collected 14 and 28 d after model establishment. Our findings indicate that on the 14th and 28th days following balloon injury, DABCD reduced intimal hyperplasia and inflammation and promoted vascular reendothelialization. Additionally, DABCD markedly increas...
Source: Biological and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhiming Liu Guangmie Xie Zuwei Li Hanbin Luo Jianhong Zhou Jie Cheng Xiaolin Wang Xiaoyan Huang Guohui Zou Source Type: research
Acute coronary syndrome in patients treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants: Proposed management algorithm for the first 48hours
Arch Cardiovasc Dis. 2024 Apr 12:S1875-2136(24)00058-5. doi: 10.1016/j.acvd.2024.02.012. Online ahead of print.ABSTRACTAround 10% of patients with acute coronary syndrome are treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants for various indications. The initial management of these patients is highly complex, and new guidelines specify that, only during percutaneous coronary intervention, a bolus of unfractionated heparin is recommended in one of the following circumstances: (1) if the patient is receiving a non-vitamin K antagonist oral anticoagulant; or (2) if the international normalized ra...
Source: Archives of Cardiovascular Diseases - April 21, 2024 Category: Cardiology Authors: Alexandre Salaun Emmanuel de Maistre Marl ène Daller Chan Sombrun Fr édéric Chagué Florence Bichat Luc Rochette Nicolas Danchin Laurent Fauchier Marianne Zeller Yves Cottin Source Type: research
How much data is enough data for imaging-guided PCI?
It is almost unanimously acknowledged that imaging guided percutaneous coronary intervention (PCI) improves outcomes, particularly in complex cases, where there's a mortality reduction of up to 50% [1,2]. Numerous studies have permeated the interventional landscape, that it is very difficult not to recommend intracoronary imaging when embarking on a more complex PCI. Just as no one questions the prescription of statins, for example, which reduce all-cause mortality by approximately 20 –30% (for both primary and secondary prevention) [3–5]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Alexandru Achim Source Type: research
Longer Duration DAPT in Medically Treated MI: What is the Strength of the Evidence?
A few studies have demonstrated the benefit of dual antiplatelet therapy (DAPT) during the first 3-12 months after AMI in medically managed patients (1-3). However, the benefit of more prolonged DAPT is poorly defined. The guidelines from national societies on the use of antiplatelet therapy after acute coronary syndromes (ACS) with or without percutaneous coronary intervention (PCI)/stenting continue to evolve, with more recent guidelines recommending a reduced duration and intensity of therapy in certain situations (4, 5). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Jeffrey L Anderson Tags: Editorial Source Type: research
Efficacy and safety of proton pump inhibitors on cardiovascular events and inflammatory factors in patients with upper gastrointestinal bleeding undergoing dual antiplatelet therapy
ConclusionMelena was the most frequent clinical manifestation in UGIB patients. The use of PPIs did not increase the risk of CVEs, and different PPI drugs did not affect the occurrence of CVEs. Furthermore, PPIs lowered CRP and TNF- α levels in serum of these patients. (Source: Inflammopharmacology)
Source: Inflammopharmacology - April 20, 2024 Category: Drugs & Pharmacology Source Type: research
