An audit of patient radiation doses during interventional cardiology procedures in Uttarakhand, India, and establishment of local diagnostic reference levels
The objective of this study was to investigate patient radiation doses by a dose audit of three common interventional cardiology (IC) procedures: coronary angiography (CA), percutaneous transluminal coronary angioplasty (PTCA) and CA –PTCA procedures performed in IC centres in the Uttarakhand state of India, for the establishment of local diagnostic reference levels (DRLs) and the estimation of average effective dose (Eav) for these procedures. For each procedure, the values of kerma-area product (PKA), reference air kerma (Ka,r), fluoroscopy time (FT) and the number of cine images were recorded from 1233 CA, 458 PTCA an...
Source: Radiological Physics and Technology - April 23, 2024 Category: Physics Source Type: research

A case report of ventricular fibrillation following Shockwave intravascular lithotripsy during percutaneous coronary intervention
Shockwave intravascular lithotripsy (S-IVL) is widely used during percutaneous coronary intervention (PCI) of calcified coronary arteries. Ventricular capture beats during S-IVL are common but arrhythmias are ... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 23, 2024 Category: Cardiology Authors: Lars Jakobsen, Evald H øj Christiansen and Troels Thim Tags: Case Report Source Type: research

A case of coronary artery compression syndrome resulting from peri-valvular regurgitation and long-standing atrial fibrillation
J Cardiol Cases. 2024 Jan 6;29(4):157-160. doi: 10.1016/j.jccase.2023.12.003. eCollection 2024 Apr.ABSTRACTA man in his 70s with a history of mitral valve replacement (MVR) and long-standing persistent atrial fibrillation (AF) presented with effort angina. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA). As it was an emergent case, PCI (percutaneous coronary intervention) was selected for treatment. Intravascular ultrasonography revealed no atherosclerotic lesions in the LMCA. The LMCA was effectively dilated by the drug-eluting stent. No elevation in intracardiac pressure was observed...
Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: Keisuke Suzuki Yoshiaki Mibiki Mai Suzuki Hiroshi Nakagata Kosuke Aoki Eiji Sato Yoshihiro Yamashina Takehiko Miyashita Akihiko Ishida Tetsuo Yagi Source Type: research

Sex-based Differences in Complex Percutaneous Coronary Intervention - Insights from COMPLEX Registry
Hellenic J Cardiol. 2024 Apr 20:S1109-9666(24)00080-0. doi: 10.1016/j.hjc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38648939 | DOI:10.1016/j.hjc.2024.04.005 (Source: Hellenic Journal of Cardiology)
Source: Hellenic Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Sylwia Iwa ńczyk Samir Ahmad Dit Al Hakim Marta Skrzypi ńska Zofia Stanisz Patrycja Wo źniak Weronika Go ściniak Aleksander Araszkiewicz Fatima Al Salman Ali Hok Marwan Mhanna Wiktoria Chylinska W łodzimierz Skorupski Micha ł Lesiak Marek Grygier Ma Source Type: research

Acute coronary syndrome in patients treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants: Proposed management algorithm for the first 48hours
Arch Cardiovasc Dis. 2024 Apr 12:S1875-2136(24)00058-5. doi: 10.1016/j.acvd.2024.02.012. Online ahead of print.ABSTRACTAround 10% of patients with acute coronary syndrome are treated by vitamin K antagonists or non-vitamin K antagonist oral anticoagulants for various indications. The initial management of these patients is highly complex, and new guidelines specify that, only during percutaneous coronary intervention, a bolus of unfractionated heparin is recommended in one of the following circumstances: (1) if the patient is receiving a non-vitamin K antagonist oral anticoagulant; or (2) if the international normalized ra...
Source: Archives of Cardiovascular Diseases - April 21, 2024 Category: Cardiology Authors: Alexandre Salaun Emmanuel de Maistre Marl ène Daller Chan Sombrun Fr édéric Chagué Florence Bichat Luc Rochette Nicolas Danchin Laurent Fauchier Marianne Zeller Yves Cottin Source Type: research

Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels via VEGF Signaling Pathway Activation by miRNA-126
In this study, we clarified the mechanism by which Detoxification and Activating Blood Circulation Decoction (DABCD) promotes vascular reendothelialization to avoid ISR by miRNA-126-mediated modulation of the vascular endothelial growth factor (VEGF) signaling pathway. A rat model of post-PCI restenosis was established by balloon injury. The injured aortic segment was collected 14 and 28 d after model establishment. Our findings indicate that on the 14th and 28th days following balloon injury, DABCD reduced intimal hyperplasia and inflammation and promoted vascular reendothelialization. Additionally, DABCD markedly increas...
Source: Biological and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhiming Liu Guangmie Xie Zuwei Li Hanbin Luo Jianhong Zhou Jie Cheng Xiaolin Wang Xiaoyan Huang Guohui Zou Source Type: research

How much data is enough data for imaging-guided PCI?
It is almost unanimously acknowledged that imaging guided percutaneous coronary intervention (PCI) improves outcomes, particularly in complex cases, where there's a mortality reduction of up to 50% [1,2]. Numerous studies have permeated the interventional landscape, that it is very difficult not to recommend intracoronary imaging when embarking on a more complex PCI. Just as no one questions the prescription of statins, for example, which reduce all-cause mortality by approximately 20 –30% (for both primary and secondary prevention) [3–5]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Alexandru Achim Source Type: research

Longer Duration DAPT in Medically Treated MI: What is the Strength of the Evidence?
A few studies have demonstrated the benefit of dual antiplatelet therapy (DAPT) during the first 3-12 months after AMI in medically managed patients (1-3). However, the benefit of more prolonged DAPT is poorly defined. The guidelines from national societies on the use of antiplatelet therapy after acute coronary syndromes (ACS) with or without percutaneous coronary intervention (PCI)/stenting continue to evolve, with more recent guidelines recommending a reduced duration and intensity of therapy in certain situations (4, 5). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Jeffrey L Anderson Tags: Editorial Source Type: research

Efficacy and safety of proton pump inhibitors on cardiovascular events and inflammatory factors in patients with upper gastrointestinal bleeding undergoing dual antiplatelet therapy
ConclusionMelena was the most frequent clinical manifestation in UGIB patients. The use of PPIs did not increase the risk of CVEs, and different PPI drugs did not affect the occurrence of CVEs. Furthermore, PPIs lowered CRP and TNF- α levels in serum of these patients. (Source: Inflammopharmacology)
Source: Inflammopharmacology - April 20, 2024 Category: Drugs & Pharmacology Source Type: research

Outcomes of Percutaneous Revascularization in Severe Ischemic Left Ventricular Dysfunction
This article presents a comprehensive review of coronary revascularization versus optimal medical therapy (OMT) in patients with severe ischemic left ventricular dysfunction.Recent FindingsThe REVIVED-BCIS2 trial randomized 700 patients with extensive coronary artery disease and left ventricular (LV) ejection fraction (LVEF)  ≤ 35% and viability in more than four dysfunctional myocardial segments to percutaneous coronary intervention (PCI) plus OMT versus OMT alone. Over a median duration of 41 months, there was no difference in the composite of all-cause mortality, heart failure hospitalization, or improvement i n ...
Source: Current Cardiology Reports - April 20, 2024 Category: Cardiology Source Type: research

Impact of baseline yellow plaque assessed by coronary angioscopy on vascular response after stent implantation
CONCLUSIONS: Baseline YP affected the incidence of neoatherosclerosis as well as poor neointimal coverage at 11 months after stent implantation.PMID:38641319 | DOI:10.1016/j.jjcc.2024.04.004 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 19, 2024 Category: Cardiology Authors: Takuya Tsujimura Isamu Mizote Takayuki Ishihara Daisuke Nakamura Naotaka Okamoto Tatsuya Shiraki Naoki Itaya Mitsuyoshi Takahara Takaharu Nakayoshi Osamu Iida Yosuke Hata Masami Nishino Takafumi Ueno Daisaku Nakatani Shungo Hikoso Shinsuke Nanto Toshiaki Source Type: research

Evaluation on mortality predictors after emergent percutaneous coronary intervention in acute myocardial infarction with ventricular arrhythmias: Details not to be ignored?
We have read the article “Predictors of 30-day survival after emergent percutaneous coronary intervention following ventricular tachyarrhythmias complicating acute myocardial infarction” by Kohei Ukita et al [1]. In the study Immediate CPR and single-vessel CAD were significant predictors of 30-day survival after emerge nt PCI following VF or pulseless VT complicating AMI in patients . In univariate analysis, absence of diabetes and low arterial lactate value were associated with 30-day survival. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 19, 2024 Category: Cardiology Authors: Aytu ğ Al, Erdi Babayiğit, Bülent Görenek Source Type: research

Clinical and economic outcomes of assigning percutaneous coronary intervention patients to contrast-sparing strategies based on the predicted risk of contrast-induced acute kidney injury
CONCLUSIONS.: Assignment to contrast-sparing regimens at a predicted risk threshold close to the underlying incidence of CI-AKI is projected to result in significant clinical and economic benefits.PMID:38632967 | DOI:10.1080/13696998.2024.2334180 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 18, 2024 Category: Health Management Authors: Robert I Griffiths Aparna Bhave Alysha M McGovern Liesl M Hargens Craig A Solid Amit P Amin Source Type: research

Isthmin-1 alleviates cardiac ischemia/reperfusion injury through cGMP-PKG signaling pathway
CONCLUSION: ISM1 can protect against cardiac I/R injury through cGMP-PKG signaling pathway, and it is a promising therapeutic and predictive target of cardiac I/R injury.PMID:38637328 | DOI:10.1093/cvr/cvae077 (Source: Cell Research)
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Min Hu Xin Zhang Can Hu Zhen-Guo Ma Sha-Sha Wang Teng Teng Xiao-Feng Zeng Qi-Zhu Tang Source Type: research

Acute myocardial infarction with e ‐cigarette or vaping‐use associated lung injury in a young Filipino vape user
We present a 22-year-old Filipino male with sudden chest pain. He had no known comorbidities but had a two-year history of daily vape use. Work-up revealed elevated cardiac markers, anteroseptal ST-elevation myocardial infarction, hypokinesia of the anterior wall and interventricular septum, and an ejection fraction of 30%. Chest radiography showed consolidation pneumonia but culture studies and Biofire Pneumonia Panel were negative for microbial detection. Coronary angiography revealed chronic total obstruction of the mid-left anterior descending (LAD) and right coronary arteries (RCA). Percutaneous coronary angioplasty o...
Source: Respirology Case Reports - April 18, 2024 Category: Respiratory Medicine Authors: Margarita Isabel C. Fernandez, Margaret Francine Co, Janine Bianca Marie Rafael, Regiel Christian Mag ‐usara, Vanessa Ediza, Rafael Luis Gavino, Jan Christian Feliciano, Nigel Jeronimo Santos, Mark Andrian Yano, Julian Alexander Huibonhoa, Ric Tags: CASE REPORT Source Type: research