Prevalence and Predictors of Emergency Medical Service Use in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction
We aim to describe prevalence of Emergency Medical Service (EMS) use, investigate factors predictive of EMS use, and determine if EMS use predicts treatment delay and mortality in our ST-elevation myocardial infarction (STEMI) cohort. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - April 2, 2024 Category: Cardiology Authors: Arul Baradi, Diem T. Dinh, Angela Brennan, Dion Stub, Jithendra Somaratne, Sonny Palmer, Ziad Nehme, Emily Andrew, Karen Smith, Danny Liew, Christopher M. Reid, Jeffrey Lefkovits, Andrew Wilson Tags: Original Article Source Type: research
Real-world performance of indobufen versus aspirin after percutaneous coronary intervention: insights from the ASPIRATION registry
Indobufen is widely used in patients with aspirin intolerance in East Asia. The OPTION trial launched by our cardiac center examined the performance of indobufen based dual antiplatelet therapy (DAPT) after pe... (Source: BMC Medicine)
Source: BMC Medicine - April 2, 2024 Category: Internal Medicine Authors: Chunfeng Dai, Muyin Liu, Zheng Yang, Youran Li, You Zhou, Danbo Lu, Yan Xia, Ao Chen, Chenguang Li, Hao Lu, Yuxiang Dai, Jianying Ma, Zhangwei Chen, Juying Qian and Junbo Ge Tags: Research article Source Type: research
Risk and Benefit of Secondary Prevention with Aspirin Versus P2Y12 Inhibitor in CAD Patients
Clinical question: In patients with coronary artery disease (CAD), what is the difference in risk and benefit between secondary prevention with aspirin (ASA) versus a P2Y12 inhibitor?
Background: Lifelong ASA is the mainstay of care for patients with CAD who require secondary prevention. This is predicated on studies from several decades ago. Subsequent studies examining P2Y12 monotherapy versus ASA have had inconsistent results.
Study design: Systematic review and meta-analysis
Setting: Seven randomized clinical trials from 1996 to 2021 were found to meet the criteria for analysis.
Synopsis: 24,325 patients were included ...
Source: The Hospitalist - April 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Cardiology In the Literature Source Type: research
Intravascular Imaging for Guiding Percutaneous Coronary Intervention: What Does the Totality of Data Suggest, and Where Should We Go?
Circulation. 2024 Apr 2;149(14):1087-1089. doi: 10.1161/CIRCULATIONAHA.123.067916. Epub 2024 Apr 1.NO ABSTRACTPMID:38557127 | DOI:10.1161/CIRCULATIONAHA.123.067916 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Akiko Maehara Yoichiro Sugizaki Source Type: research
The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention
CONCLUSIONS: High levels of SIRI are independent predictors of CA-AKI and long-term mortality in patients undergoing elective PCI.PMID:38561250 | DOI:10.1080/0886022X.2024.2330621 (Source: Renal Failure)
Source: Renal Failure - April 1, 2024 Category: Urology & Nephrology Authors: Jun-Han Chen Li-Wei Zhang Wen-Jia Liang Wei-Ze Lin Xiao-Fang Chen Zhi-Jie Lin Chang-Xi Wang Kai-Yang Lin Yan-Song Guo Source Type: research
TRIM27 Promotes Endothelial Progenitor Cell Apoptosis in Patients with In-Stent Restenosis by Ubiquitinating TBK1
Appl Biochem Biotechnol. 2024 Apr 1. doi: 10.1007/s12010-024-04933-3. Online ahead of print.ABSTRACTApproximately 2-10% in-stent restenosis (ISR) may occur following percutaneous coronary intervention (PCI) despite the use of modern drug-eluting stents (DES); thus, our study aimed to explore the effects of tripartite motif-containing (TRIM) 27 on ISR and the underlying mechanism. For this purpose, a total of 42 patients undergoing coronary angiography who had prior coronary angiography with DES implantation were recruited. Endothelial progenitor cells (EPCs) markers (defined as CD34 and vascular endothelial growth factorec...
Source: Applied Biochemistry and Biotechnology - April 1, 2024 Category: Biochemistry Authors: Bo Liu Huai Wang Wenhao Xie Ting Gong Source Type: research
The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention
CONCLUSIONS: High levels of SIRI are independent predictors of CA-AKI and long-term mortality in patients undergoing elective PCI.PMID:38561250 | PMC:PMC10986433 | DOI:10.1080/0886022X.2024.2330621 (Source: Renal Failure)
Source: Renal Failure - April 1, 2024 Category: Urology & Nephrology Authors: Jun-Han Chen Li-Wei Zhang Wen-Jia Liang Wei-Ze Lin Xiao-Fang Chen Zhi-Jie Lin Chang-Xi Wang Kai-Yang Lin Yan-Song Guo Source Type: research
Evaluating biomarkers for contrast-induced nephropathy following coronary interventions: an umbrella review on meta-analyses
ConclusionNGAL demonstrated superior diagnostic performance, exhibiting the highest AUC, positive likelihood ratio, and diagnostic odds ratio among biomarkers for CIN, followed by cystatin-C, and uKIM-1. These findings underscore the potential clinical utility of NGAL, cystatin-C and uKIM-1 in predicting and assessing CIN.Graphical Abstract (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 1, 2024 Category: Research Source Type: research
Clinical Outcomes of Renal Transplant Recipients Undergoing Percutaneous Coronary Intervention
Clinical outcomes of patients with renal transplant (RT) undergoing percutaneous coronary intervention (PCI) remain poorly elucidated. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - April 1, 2024 Category: Cardiology Authors: Wayne C. Zheng, Nicole Evans, Diem Dinh, Jason E. Bloom, Angela L. Brennan, Jocasta Ball, Jeffrey Lefkovits, James A. Shaw, Christopher M. Reid, William Chan, Dion Stub Tags: Original Article Source Type: research
The effect of coronary stent policies on the risk of percutaneous coronary intervention among acute coronary syndrome patients in Shanghai: Real-world evidence
This study aimed to analyze the effect of coronary stent policies implemented in Shanghai on the risk of percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) inpatients based on real-world data. MethodsTwo retrospective cohorts of inpatients with a first diagnosis of ACS who had undergone PCI for the first time in the previous year in Shanghai hospitals were examined (one for the postpolicy period and the other for the prepolicy period).χ2 tests were used to compare categorical variables between the two cohorts. Single- and multivariate Cox proportional hazards models were used to compare the risk of ...
Source: PLoS One - April 1, 2024 Category: Biomedical Science Authors: Zhenyi Shao Source Type: research
Systemic immune-inflammation index as a novel predictor of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention: a meta-analysis of cohort studies
The Systemic Immune-Inflammation Index (SII), a novel marker of inflammation based on neutrophil, platelet, and lymphocyte counts, has demonstrated potential prognostic value in patients undergoing percutaneou... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 1, 2024 Category: Cardiology Authors: Chunyu Zhang, Minghao Li, Lin Liu, Li Deng, Xie Yulei, Yi Zhong, Bin Liao, Lu Yu and Jian Feng Tags: Systematic Review Source Type: research
Left Ventricular Assist Device Recipients with a History of Cardiovascular Disease or Cardiothoracic Surgery Have Increased Mortality
Purpose: Right ventricular failure (RVF) is a major complication following left ventricular assist device (LVAD) placement and can significantly increase mortality. The identification of preoperative risk factors could help delineate the risk for RVF in LVAD recipients. While early RVF is well established, the risk factors for late RVF remain are not well established. Our goal was to evaluate the prevalence of late RVF in LVAD patients with a history of coronary artery disease (CAD) and prior cardiac surgery (coronary artery bypass grafting [CABG] or percutaneous coronary intervention). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.S. Scott, S. Smith Source Type: research
Percutaneous Coronary Intervention in Pediatric Transplant Recipients- Delaying the Inevitable
Purpose: Coronary allograft vasculopathy (CAV) is the leading cause of allograft failure in pediatric patients. Atherosclerotic coronary disease is usually focal and is managed with lifestyles modifications, medications and percutaneous interventions; however, CAV is more diffuse. Limited data is available regarding use of percutaneous interventions (PCI) for CAV. We sought to retrospectively review patients who were transplanted as pediatric patients and who underwent PCI for CAV and evaluate their outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M.S. Purlee, , D. Lopez-Colon, M. Bleiweis, J. Jacobs, G. Peek, F. Fricker, B. Pietra, H. Vyas, J. Fudge, D. Gupta Source Type: research
Risk Prediction and Standardisation of Cardiogenic Shock Care
Cardiogenic shock (CS), specifically complicating acute myocardial infarction (AMI), continues to be associated with high morbidity and mortality despite advances in pharmacotherapy, percutaneous coronary intervention (PCI) techniques, and temporary mechanical circulatory support (MCS) device technology [1]. Poor in-hospital and long-term outcomes are largely attributable to heterogeneity in the presentation, aetiology, severity, and clinical assessment of CS, which continues to be challenging [2]. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - April 1, 2024 Category: Cardiology Authors: Saraschandra Vallabhajosyula, Vinayak Nagaraja Tags: Editorial Source Type: research
Low-dose prasugrel versus standard-dose ticagrelor in east Asian patients with acute coronary syndrome
This study included ACS patients who underwent percutaneous coronary intervention and, at discharge between January 1, 2018 and December 31, 2020, were prescribed with low-dose prasugrel plus aspirin or standard-dose ticagrelor plus aspirin. Stabilized inve rse probability of treatment weighting was used to balance the covariates across these two groups. The primary effectiveness outcome was a composite of acute myocardial infarction, ischemic stroke, and cardiovascular death; the secondary effectiveness outcome was each of the individual components of the primary outcome, transient ischemic attack, and repeat revasculariz...
Source: Journal of Thrombosis and Thrombolysis - March 31, 2024 Category: Hematology Source Type: research
