Appendectomy versus antibiotic treatment for acute appendicitis
CONCLUSIONS: Antibiotics may be associated with higher rates of unsuccessful treatment for 76 per 1000 people, although differences may not be clinically significant. It is uncertain if antibiotics increase length of hospital stay by half a day. Antibiotics may reduce wound infections. A third of the participants initially treated with antibiotics required subsequent appendectomy or two-thirds avoided surgery within one year, but the evidence is very uncertain. There were too few data from the included studies to comment on major complications.PMID:38682788 | PMC:PMC11057219 | DOI:10.1002/14651858.CD015038.pub2 (Source: Co...
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Brett Doleman Siv Fonnes Jon N Lund Hannah Boyd-Carson Hannah Javanmard-Emamghissi Susan Moug Marianne Hollyman Gillian Tierney Samson Tou John P Williams Source Type: research
Appendectomy versus antibiotic treatment for acute appendicitis
CONCLUSIONS: Antibiotics may be associated with higher rates of unsuccessful treatment for 76 per 1000 people, although differences may not be clinically significant. It is uncertain if antibiotics increase length of hospital stay by half a day. Antibiotics may reduce wound infections. A third of the participants initially treated with antibiotics required subsequent appendectomy or two-thirds avoided surgery within one year, but the evidence is very uncertain. There were too few data from the included studies to comment on major complications.PMID:38682788 | PMC:PMC11057219 | DOI:10.1002/14651858.CD015038.pub2 (Source: Co...
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Brett Doleman Siv Fonnes Jon N Lund Hannah Boyd-Carson Hannah Javanmard-Emamghissi Susan Moug Marianne Hollyman Gillian Tierney Samson Tou John P Williams Source Type: research
Clostridiodes difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 Apr 27. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatment of...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research
A comparative assessment of microbiocenosis of saliva and oropharynx in patients with migraine
CONCLUSION: A comparative assessment of the microbiota of a smear from the posterior wall of the oropharynx and saliva using MMSM showed the presence of dysbiosis both in the oropharynx and in the saliva of patients with migraine. However, there were fewer deviations from the norm in saliva, therefore, for diagnostic purposes, a smear from the posterior wall of the oropharynx is more significant as a biomarker for patients with migraine.PMID:38676678 | DOI:10.17116/jnevro202412404155 (Source: Herpes)
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: I L Naydenova A B Danilov A V Simonova A A Pilipovich E G Filatova Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
Clostridiodes difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 Apr 27. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatment of...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
A comparative assessment of microbiocenosis of saliva and oropharynx in patients with migraine
CONCLUSION: A comparative assessment of the microbiota of a smear from the posterior wall of the oropharynx and saliva using MMSM showed the presence of dysbiosis both in the oropharynx and in the saliva of patients with migraine. However, there were fewer deviations from the norm in saliva, therefore, for diagnostic purposes, a smear from the posterior wall of the oropharynx is more significant as a biomarker for patients with migraine.PMID:38676678 | DOI:10.17116/jnevro202412404155 (Source: Herpes)
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: I L Naydenova A B Danilov A V Simonova A A Pilipovich E G Filatova Source Type: research
Clostridiodes difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 Apr 27. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatment of...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
Clostridiodes difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 Apr 27. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatment of...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
Clostridioides difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 May 2:1-10. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatmen...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
Clostridioides difficile Colitis
Surg Clin North Am. 2024 Jun;104(3):545-556. doi: 10.1016/j.suc.2023.11.005. Epub 2023 Dec 26.ABSTRACTClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at ...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Luke Pumiglia Lexi Wilson Laila Rashidi Source Type: research
