Probiotic formulations and gastro-intestinal diseases in the paediatric population: a narrative review
CONCLUSION: This study concludes that single-organism and composite probiotics are effective complementary therapies for treating gastrointestinal disorders in the pediatric population. Hence, healthcare professionals should consider using probiotics in standard treatment regimens, and educating guardians can enhance the benefits of probiotic therapy. Further research is recommended to identify the optimal strains and dosages for specific conditions and demographics. The integration of probiotics in clinical practice and ongoing research can contribute to reducing the incidence and severity of gastrointestinal disorders in...
Source: Hand Surgery - May 2, 2024 Category: Surgery Authors: Amna Siddiqui Ramsha Haider Syeda Ilsa Aaqil Laiba Imran Vohra Khulud Qamar Areesha Jawed Nabeela Fatima Alishba Adnan Vidhi Parikh Sidhant Ochani Md Al Hasibuzzaman Source Type: research
Probiotic formulations and gastro-intestinal diseases in the paediatric population: a narrative review
CONCLUSION: This study concludes that single-organism and composite probiotics are effective complementary therapies for treating gastrointestinal disorders in the pediatric population. Hence, healthcare professionals should consider using probiotics in standard treatment regimens, and educating guardians can enhance the benefits of probiotic therapy. Further research is recommended to identify the optimal strains and dosages for specific conditions and demographics. The integration of probiotics in clinical practice and ongoing research can contribute to reducing the incidence and severity of gastrointestinal disorders in...
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Amna Siddiqui Ramsha Haider Syeda Ilsa Aaqil Laiba Imran Vohra Khulud Qamar Areesha Jawed Nabeela Fatima Alishba Adnan Vidhi Parikh Sidhant Ochani Md Al Hasibuzzaman Source Type: research
Probiotic formulations and gastro-intestinal diseases in the paediatric population: a narrative review
CONCLUSION: This study concludes that single-organism and composite probiotics are effective complementary therapies for treating gastrointestinal disorders in the pediatric population. Hence, healthcare professionals should consider using probiotics in standard treatment regimens, and educating guardians can enhance the benefits of probiotic therapy. Further research is recommended to identify the optimal strains and dosages for specific conditions and demographics. The integration of probiotics in clinical practice and ongoing research can contribute to reducing the incidence and severity of gastrointestinal disorders in...
Source: Hand Surgery - May 2, 2024 Category: Surgery Authors: Amna Siddiqui Ramsha Haider Syeda Ilsa Aaqil Laiba Imran Vohra Khulud Qamar Areesha Jawed Nabeela Fatima Alishba Adnan Vidhi Parikh Sidhant Ochani Md Al Hasibuzzaman Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology : WJG - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Theophylline-based control of repA on a Clostridioides difficile plasmid for use in allelic exchange
Anaerobe. 2024 Apr 29:102858. doi: 10.1016/j.anaerobe.2024.102858. Online ahead of print.ABSTRACTHistorically, mutagenesis in the non-model enteropathogenic bacterium Clostridioides difficile has been challenging. Developing a versatile and reliable method of generating targeted mutations in C. difficile is important to further our understanding of its pathogenesis. Some of the most common targeted mutagenesis systems rely on allelic exchange mediated by either uracil auxotrophy combined with a toxic uracil precursor, a toxin / anti-toxin system, group II introns, or CRISPR/Cas mutagenesis. However, each of these methods s...
Source: Anaerobe - May 1, 2024 Category: Microbiology Authors: Joshua N Brehm Joseph A Sorg Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology : WJG - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Theophylline-based control of repA on a Clostridioides difficile plasmid for use in allelic exchange
Anaerobe. 2024 Apr 29:102858. doi: 10.1016/j.anaerobe.2024.102858. Online ahead of print.ABSTRACTHistorically, mutagenesis in the non-model enteropathogenic bacterium Clostridioides difficile has been challenging. Developing a versatile and reliable method of generating targeted mutations in C. difficile is important to further our understanding of its pathogenesis. Some of the most common targeted mutagenesis systems rely on allelic exchange mediated by either uracil auxotrophy combined with a toxic uracil precursor, a toxin / anti-toxin system, group II introns, or CRISPR/Cas mutagenesis. However, each of these methods s...
Source: Anaerobe - May 1, 2024 Category: Microbiology Authors: Joshua N Brehm Joseph A Sorg Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology : WJG - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research
Impact of including productivity costs in economic analyses of vaccines for C. difficile infections and infant respiratory syncytial virus, in a UK setting
It has been estimated that vaccines can accrue a relatively large part of their value from patient and carer productivity. Yet, productivity value is not commonly or consistently considered in health economic ... (Source: Cost Effectiveness and Resource Allocation)
Source: Cost Effectiveness and Resource Allocation - April 30, 2024 Category: Health Management Authors: Margherita Neri, Janne C. Mewes, Fernando Albuquerque de Almeida, Sophia Stoychev, Nadia Minarovic, Apostolos Charos, Kimberly M. Shea and Lotte M.G. Steuten Tags: Research Source Type: research
An Innovative Academic Clinical Partnership
NewYork-Presbyterian Hospital (NYPH) evaluates quality and patient safety (QPS) metrics and goals for the hospital enterprise and at each hospital site. The hospital QPS committee lead an initiative focused on C-difficile (C-diff) with a multifaceted strategy to meet the standardized infection ratio (SIR) goals for 2021. As part of this program, an innovative practice partnership between NYPH and Columbia University School of Nursing (CUSON) emerged to create an audit program while providing students first-hand experience with hospital-based quality improvement initiatives. (Source: Nurse Leader)
Source: Nurse Leader - April 30, 2024 Category: Nursing Authors: Susan D. Chin, Heidi Hahn-Schroeder, Candice Smith, MariLou Prado-Inzerillo Tags: Featured article Source Type: research
Appendectomy versus antibiotic treatment for acute appendicitis
CONCLUSIONS: Antibiotics may be associated with higher rates of unsuccessful treatment for 76 per 1000 people, although differences may not be clinically significant. It is uncertain if antibiotics increase length of hospital stay by half a day. Antibiotics may reduce wound infections. A third of the participants initially treated with antibiotics required subsequent appendectomy or two-thirds avoided surgery within one year, but the evidence is very uncertain. There were too few data from the included studies to comment on major complications.PMID:38682788 | DOI:10.1002/14651858.CD015038.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 29, 2024 Category: General Medicine Authors: Brett Doleman Siv Fonnes Jon N Lund Hannah Boyd-Carson Hannah Javanmard-Emamghissi Susan Moug Marianne Hollyman Gillian Tierney Samson Tou John P Williams Source Type: research
