Switchable Dual Circularly Polarized Luminescence in Through-Space Conjugated Chiral Foldamers
Angew Chem Int Ed Engl. 2024 May 2:e202407605. doi: 10.1002/anie.202407605. Online ahead of print.ABSTRACTOrganic materials with switchable dual circularly polarized luminescence (CPL) are highly desired because they can not only directly radiate tunable circularly polarized light themselves but also induce CPL for guests by providing chiral environment in self-assembled structures or serving as the hosts for energy transfer systems. However, most organic molecules only exhibit single CPL and it remains challenging to develop organic molecules with dual CPL. Herein, novel through-space conjugated chiral foldamers are const...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Pingchuan Shen Shaoshao Jiao Zeyan Zhuang Xiaobing Dong Shaoxin Song Jinshi Li Ben Zhong Tang Zujin Zhao Source Type: research
Organocatalytic Enantioselective 1,12-Addition of Alkynyl Biphenyl Quinone Methides Formed In Situ
Angew Chem Int Ed Engl. 2024 May 2:e202400143. doi: 10.1002/anie.202400143. Online ahead of print.ABSTRACTThe chemistry of quinone methides formed in situ has been flourishing in recent years. In sharp contrast, the development and utilization of biphenyl quinone methides are rare. Herein, we achieved a remote stereocontrolled 1,12-conjugate addition of biphenyl quinone methides formed in situ for the first time. In the presence of a suitable chiral phosphoric acid, alkynyl biphenyl quinone methides were generated from α-[4-(4-hydroxyphenyl)phenyl]propargyl alcohols, followed by enantioselective 1,12-conjugate addition wi...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Xing Wang Boming Shen Meiwen Liu Ziyang Wang Chang Liu Pengfei Li Peiyuan Yu Wenjun Li Source Type: research
Probing Particle-Carbon/Binder Degradation Behavior in Fatigued Layered Cathode Materials through Machine Learning Aided Diffraction Tomography
Angew Chem Int Ed Engl. 2024 May 3:e202403189. doi: 10.1002/anie.202403189. Online ahead of print.ABSTRACTUnderstanding how reaction heterogeneity impacts cathode materials during Li-ion battery (LIB) electrochemical cycling is pivotal for unraveling their electrochemical performance. Yet, experimentally verifying these reactions has proven to be a challenge. To address this, we employed scanning μ-XRD computed tomography to scrutinize Ni-rich layered LiNi0.6Co0.2Mn0.2O2 (NCM622) and Li-rich layered Li[Li0.2Ni0.2Mn0.6]O2 (LLNMO). By harnessing machine learning (ML) techniques, we scrutinized an extensive dataset of μ-XRD...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Weibo Hua Jinniu Chen Dario Ferreira Sanchez Bj örn Schwarz Yang Yang Anatoliy Senyshyn Zhenguo Wu Chong-Heng Shen Michael Knapp Helmut Ehrenberg Sylvio Indris Xiaodong Guo Xiaoping Ouyang Source Type: research
Dimensional Regulation in Metal-Free Perovskites by Compositional Engineering to Achieve Record Low X-ray Detection Limits
This study expands the dimensionality control strategies for MFPs and introduces, for the first time, the potential of 2D MFPs as high-performance X-ray detectors, thereby enriching the diversity of the MFPs family.PMID:38701362 | DOI:10.1002/anie.202407048 (Source: Angewandte Chemie)
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Pengxiang Dong Chensheng Lin Ning Ye Min Luo Source Type: research
Photon Upconversion Cooperates with Downshifting in Chiral Systems: Modulation, Amplification, and Applications of Circularly Polarized Luminescence
Angew Chem Int Ed Engl. 2024 May 3:e202406524. doi: 10.1002/anie.202406524. Online ahead of print.ABSTRACTCircularly polarized luminescence (CPL)-active materials are increasingly recognized for their potential applications such as 3D imaging, data storage, and optoelectronic devices. Typically, CPL materials have required high-energy (HE) photons for excitation to emit low-energy (LE) circularly polarized light, a process known as downshifting CPL (DSCPL). However, the emergence of upconverted CPL (UCCPL), where the absorption of multi LE photons results in the emission of a single HE photon with circular polarization, ha...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Tonghan Zhao Pengfei Duan Source Type: research
Ultrastrong Graphene Sheets Assembled with Nanoconfined Water
Angew Chem Int Ed Engl. 2024 May 3:e202405964. doi: 10.1002/anie.202405964. Online ahead of print.ABSTRACTHighly ordered assembly of two-dimensional (2D) nanoplatelets plays a key role in enhancing the mechanical properties of layered nanocomposites. Layer-by-layer (LbL) assembly, vacuum-assisted filtration, and blade coating have been used to fabricate layered nanocomposites. However, the intrinsic wrinkles of 2D nanoplatelets and defects derived from assembling approaches make it difficult to align 2D nanoplatelets. A team of Prof. Qunfeng Cheng at Beihang University with collaborator of Prof. Ray H. Baughman at Universi...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Zhiyong Tang Source Type: research
An in-situ-tag-generation proximity labeling technology for recording cellular interactions
Angew Chem Int Ed Engl. 2024 May 3:e202407109. doi: 10.1002/anie.202407109. Online ahead of print.ABSTRACTObtaining information about cellular interactions is fundamental to the elucidation of physiological and pathological processes. Proximity labeling technologies have been widely used to report cellular interactions in situ; however, the reliance on addition of tag molecules typically restricts their application to regions where tags can readily diffuse, while the application in, for example, solid tissues, is susceptible. Here, we propose an "in-situ-tag-generation mechanism" and develop the GalTag technology based on ...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Yunyan Yao Ru Jia Chuanming Liu Haiqi Wang Ting Li Xiaocui Zheng Tong Zhong Nan Feng Jiahui Sun Ke Li Ran Xie Lijun Ding Chao Yan Lin Ding Huangxian Ju Source Type: research
Fluorinated Surface Engineering towards High-rate and Durable Potassium-ion Battery
We report an ultra-thin and KF-enriched SEI triggered by tuned fluorinated surface design in electrode. Our results reveal that fluorination engineering alters the interfacial chemical environment to facilitate inherited electronic conductivity, enhance adsorption ability of potassium, induce localized surface polarization to guide electrolyte decomposition behavior for SEI formation, and especially, enrich the KF crystals in SEI by self-sacrifice from C-F bond cleavage. Hence, the regulated fluorinated electrode with generated ultra-thin, uniform, and KF-enriched SEI shows improved capacity of 439.3 mAh g-1 (3.82 mAh cm--...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Xixue Zhang Feng Wu Difan Fang Renjie Chen Li Li Source Type: research
ß-Phenethylamine Synthesis via Latent Dual Electrophilicity of N-Pyridinium Aziridines
Angew Chem Int Ed Engl. 2024 May 3:e202406335. doi: 10.1002/anie.202406335. Online ahead of print.ABSTRACTß-Phenethylamines are widely represented in biologically and pharmacologically active organic small molecules. Here, we introduce N-pyridinium aziridines as latent dual electrophiles for the synthesis of ß-phenethylamines. Bromide-promoted ring opening generates ß-halopyridinium amines. Selective Ni-catalyzed C-C cross-coupling between organozinc nucleophiles and the benzylic C-Br electrophile affords a diverse family of ß-functionalized phenethylaminopyridinium salts, and coupling is stereoconvergent in the presen...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Samya Samanta Promita Biswas Braeden O'Bannon David C Powers Source Type: research
Spin-State Control in Dysprosium(III) Metallacrown Magnets via Thioacetal Modification
Angew Chem Int Ed Engl. 2024 May 3:e202404271. doi: 10.1002/anie.202404271. Online ahead of print.ABSTRACTIntegrating controllable spin states into single-molecule magnets (SMMs) enables precise manipulation of magnetic interactions at a molecular level, but remains a synthetic challenge. Herein, we developed a 3d-4f metallacrown (MC) magnet [DyNi5(quinha)5(Clsal)2(py)8](ClO4)∙4H2O (H2quinha = quinaldichydroxamic acid, HClsal = 5-chlorosalicylaldehyde) wherein a square planar NiII is stabilized by chemical stacking. Thioacetal modification was employed via post-synthetic ligand substitutions and yielded [DyNi5(quinha)5(C...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Wei Deng Si-Guo Wu Ze-Yu Ruan Ya-Ping Gong Shan-Nan Du Hai-Ling Wang Yan-Cong Chen Wei-Xiong Zhang Jun-Liang Liu Ming-Liang Tong Source Type: research
Metal Ions Trigger the Gelation of Cysteine-Containing Peptide-Appended Coordination Cages
We report a series of coordination cages that incorporate peptide chains at their vertices, prepared through subcomponent self-assembly. Three distinct heterochiral tripeptide subcomponents were incorporated, each exhibiting an L-D-L stereoconfiguration. Through this approach, we prepared and characterized three tetrahedral metal-peptide cages that incorporate thiol and methylthio groups. The gelation of these cages wasprobed through the binding of additional metal ions, with the metal-peptide cages acting as junctions, owing to the presence of sulfur atoms on the peripheral peptides. Gels were obtained with cages bearing ...
Source: Angewandte Chemie - May 3, 2024 Category: Chemistry Authors: Meng Li Huangtianzhi Zhu Simone Adorinni Weichao Xue Andrew Heard Ana M Garcia Slavko Kralj Jonathan Russell Nitschke Silvia Marchesan Source Type: research
Improving hemocompatibility of decellularized vascular tissue by structural modification of collagen fiber
Int J Biol Macromol. 2024 May 1:132040. doi: 10.1016/j.ijbiomac.2024.132040. Online ahead of print.ABSTRACTDecellularized vascular tissue has high potential as a tissue-engineered vascular graft because of its similarity to native vessels in terms of mechanical strength. However, exposed collagen on the tissue induces blood coagulation, and low hemocompatibility is a major obstacle to its vascular application. Here we report that freeze-drying and ethanol treatment effectively modify collagen fiber structure and drastically reduce blood coagulation on the graft surface without exogenous chemical modification. Decellularize...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Atsushi Mahara Satoki Ota Le Thi Hue Kaito Shimizu Raghav Soni Kentaro Kojima Yoshiaki Hirano Sachiro Kakinoki Tetsuji Yamaoka Source Type: research
Anhydroparthenin as a dual-target inhibitor against Sterol C-24 methyltransferase and Sterol 14- α demethylase of Leishmania donovani: A comprehensive in vitro and in silico study
Int J Biol Macromol. 2024 May 1:132034. doi: 10.1016/j.ijbiomac.2024.132034. Online ahead of print.ABSTRACTParthenium hysterophorus plant has a diverse chemical profile and immense bioactive potential. It exhibits excellent pharmacological properties such as anti-cancer, anti-inflammatory, anti-malarial, microbicidal, and anti-trypanosomal. The present study aims to evaluate the anti-leishmanial potential and toxicological safety of anhydroparthenin isolated from P. hysterophorus. Anydroparthenin was extracted from the leaves of P. hysterophorus and characterized through detailed analysis of 1H, 13C NMR, and HRMS. Dye-base...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Diksha Kumari Parampreet Kour Chetan Paul Singh Rinku Choudhary Syed Mudassir Ali Sagar Bhayye Yogesh P Bharitkar Kuljit Singh Source Type: research
Chemical and physical modification of graphene oxide nano-sheets using casein, Zn-Al layered double hydroxide, alginate hydrogel, and magnetic nanoparticles for biomedical applications
Int J Biol Macromol. 2024 May 1:132047. doi: 10.1016/j.ijbiomac.2024.132047. Online ahead of print.ABSTRACTIn our study, we developed a novel nanobiocomposite using graphene oxide (GO), casein (Cas), ZnAl layered double hydroxide (LDH), sodium alginate (Alg), and Fe3O4 magnetic nanoparticles. To synthesize the GO, we used a modified Hummer's method and then covalently functionalized its surface with Cas protein. The functionalized GO was combined with as-synthesized ZnAl LDH, and the composite was conjugated with alginate hydrogel through the gelation process. Finally, we magnetized the nanobiocomposite using in-situ magne...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Ehsan Bahojb Noruzi Seyed Amir Hossein Vasigh Reza Eivazzadeh-Keihan Hooman Aghamirza Moghim Aliabadi Milad Salimi Bani Behrouz Shaabani Source Type: research
Structural and functional characteristics of pectins from three cultivars of apple (Malus pumila Mill.) pomaces
This study aimed to investigate the chemical composition, structural properties, and biological properties of pectin polysaccharides (AP-FS, AP-QG, and AP-HG) isolated from different varieties of apple pomace. Based on the methylation and nuclear magnetic resonance analyses, the structure of AP-FS was determined to be composed of an α-1,4-linked homogalacturonan backbone that exhibited high levels of O-6 methylation. All pectins exhibit potent inhibitory activity against human colon cancer and human liver cancer cells, along with immunostimulatory effects. Among them, AP-FS exhibited the highest activity level. Finally, w...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Huan Guo Hang Li Wenyi Ran Wenyue Yu Yue Xiao Renyou Gan Hong Gao Source Type: research
