Botanical Dietary Supplements Translational Research Teams (RM1 Clinical Trial Required)
Funding Opportunity RFA-OD-24-014 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support collaborative, transdisciplinary, translational research projects which advance exceptionally promising, chemically complex botanical and other natural products relevant to dietary supplements towards highly informative clinical trials of their effects on quantitative, objective measures of human resilience. Dynamic, synergistic interactions among the range of experts required to ensure rigor in all aspects of this research will be supported by a multi-PD/PI team collabora...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2024 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Chemical Countermeasures Research Program (CCRP) Administrative Supplements to Promote the Development of Pediatric Research Models of Chemical Injury and Medical Countermeasures Discovery
Notice NOT-AI-24-022 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 8, 2024 Category: Research Source Type: funding

Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AT-24-008 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) will support development, adaptation, and/or applications of computational tools to aggregate and analyze orthogonal chemical and/or biological data sets related to natural products with the aim of generating novel testable hypotheses regarding their biological activity and role in the context of whole person health research. Projects must leverage and merge multiple compatible or interoperable sources and/or types of data. Use of artificial intelligence and machine learning approaches is encouraged. ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 5, 2024 Category: Research Source Type: funding

Do I Need to Authenticate Key Biological and/or Chemical Resources? If So, How?
NIH’s Rigor and Reproducibility FAQs have been updated with new questions and answers about authenticating key biological/chemical resources: What kind of information should I include in the “Authentication of Key Biological and/or Chemical Resources” attachment? Do I need to include an “Authentication of Key Biological and/or Chemical Resources” attachment? Have more questions on this topic? Check out the Authentication of Key Biological/Chemical Resources section, or visit the complete set of Rigor and Reproducibility FAQs. (Source: NIH Extramural Nexus)
Source: NIH Extramural Nexus - January 31, 2024 Category: Research Authors: NIH Staff Tags: You Ask, We Answer Grants policy rigor Source Type: funding

Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R21 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-008 from the NIH Guide for Grants and Contracts. HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological complications. Strategies to address viral latency include silencing of HIV transcription and reactivation and clearance. The goal of this initiative is to support research aimed at (1) identification of targets and pathways by which transcriptional activity...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 20, 2023 Category: Research Source Type: funding

Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-007 from the NIH Guide for Grants and Contracts. HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological complications. Strategies to address viral latency include silencing of HIV transcription and reactivation and clearance. The goal of this initiative is to support research aimed at (1) identification of targets and pathways by which transcriptional activity...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 20, 2023 Category: Research Source Type: funding

Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-088 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunities (NOFOs) is to support investigators who have interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds. Through this NOFO, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in understanding biological processes relevan...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 13, 2023 Category: Research Source Type: funding

Dear Colleague Letter: Planning Proposals for Centers of Research Excellence in Science and Technology (CREST Centers) in Chemistry Research
Available Formats: HTML: https://www.nsf.gov/pubs/2024/nsf24029/nsf24029.jsp?WT.mc_id=USNSF_25&WT.mc_ev=clickPDF: https://www.nsf.gov/pubs/2024/nsf24029/nsf24029.pdf?WT.mc_id=USNSF_25&WT.mc_ev=clickDocument Number: nsf24029This is an NSF Program Announcements and Information item. (Source: NSF Program Announcements and Information)
Source: NSF Program Announcements and Information - December 5, 2023 Category: Science Source Type: funding

Notice of Special Interest (NOSI): Development and Application of Novel Chemical Approaches to Discover Therapeutic Targets for Substance Use Disorders
Notice NOT-DA-25-027 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 28, 2023 Category: Research Source Type: funding

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Funding Opportunity PAR-24-043 from the NIH Guide for Grants and Contracts. Reissue of PAR-18-546. The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN are responsible for conducting all studies that involve disease- or target-specific assays, models, and other research tools and receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants and can augment their pr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2023 Category: Research Source Type: funding

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Funding Opportunity PAR-24-063 from the NIH Guide for Grants and Contracts. Reissue of PAR-18-541. The Blueprint Neurotherapeutics Network (BPN) encourages applications from small businesses seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN are responsible for conducting all studies that involve disease- or target-specific assays, models, and other research tools and receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants and can augment their project w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 1, 2023 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Chemical Countermeasures Research Program (CCRP) Initiative: Additional Research Areas of Interest focusing on Ultra-Potent Synthetic (UPS) Opioids
Notice NOT-DA-23-044 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 25, 2023 Category: Research Source Type: funding

Dear Colleague Letter: NSF ANR Chemistry Lead Agency Opportunity on Sustainable Chemistry: Catalysis with Earth-Abundant Elements
Available Formats: HTML: https://www.nsf.gov/pubs/2023/nsf23157/nsf23157.jsp?WT.mc_id=USNSF_25&WT.mc_ev=clickPDF: https://www.nsf.gov/pubs/2023/nsf23157/nsf23157.pdf?WT.mc_id=USNSF_25&WT.mc_ev=clickDocument Number: nsf23157Public Comment: This is an NSF Program Announcements and Information item. (Source: NSF Program Announcements and Information)
Source: NSF Program Announcements and Information - September 26, 2023 Category: Science Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)
Notice NOT-NS-24-008 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 20, 2023 Category: Research Source Type: funding

BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
Funding Opportunity RFA-EY-23-001 from the NIH Guide for Grants and Contracts. This FOA seeks applications for unique and innovative recording and/or modulation technologies that are in the earliest stage of development, including new and untested ideas that are in the initial stages of conceptualization. Some projects may aim to increase recording or modulation capabilities by many orders of magnitude, while others may aim to improve the precision and selectivity of recording or modulation (also referred to as stimulation, perturbation, or manipulation). A wide range of modalities are appropriate including acoustic, ch...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 19, 2023 Category: Research Source Type: funding