Endocannabinoids and cortisol in plasma, aqueous and tear samples of primary angle closure glaucoma versus controls
CONCLUSIONS: Tear endocannabinoids were determined for the first time in PACG and normal with no difference between the two groups. Plasma and aqueous cortisol levels are a differentiating factor between normal and glaucoma patients with plasma endocannabinoids being remarkably higher in normals. Quality of life in glaucoma patients with high cortisol levels is poorer.PMID:38613316 | DOI:10.1177/11206721241247419 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 13, 2024 Category: Opthalmology Authors: Dewang Angmo Gazella Bruce Warjri L Gowtham Thirumurthy Velpandian Tanuj Dada Source Type: research
Case report: Introduction of an Ahmed valve implant tube into the ciliary sulcus using a guide-wire
CONCLUSION: The purpose of these cases presentations attended at our service is to demonstrate the passage of the AGV silicone tube was performed with the aid of a guide wire.PMID:38613315 | DOI:10.1177/11206721241247584 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 13, 2024 Category: Opthalmology Authors: Jo ão Leite Ana Figueiredo Rita Reis Isabel Sampaio Maria Jo ão Menéres Source Type: research
Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks
ConclusionsDM1 patients have a noteworthy occurrence of several comorbidities such as cancer, diabetes, thyroid dysfunction, and earlier cataract surgery. This highlights the importance of a comprehensive and integrative approach to the management and treatment of DM1, going beyond addressing only the primary neuromuscular symptoms. More research is required to understand the underlying mechanisms contributing to these comorbidities in DM1 patients, which may inform preventative measures and guide improvements in patient care. (Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2024 Category: Neurology Source Type: research
Aqueous humour protein dysregulation in Asian eyes with primary open angle glaucoma
Exp Eye Res. 2024 Apr 10:109887. doi: 10.1016/j.exer.2024.109887. Online ahead of print.ABSTRACTThe pathophysiology of Primary Open Angle Glaucoma (POAG) remains poorly understood. Through proteomic analysis of aqueous humour (AH) from POAG patients, we aim to identify changes in protein composition of these samples compared to control samples. High resolution mass spectrometry-based TMT6plex quantitative proteomics analysis is performed on AH samples collected from POAG patients, and compared against a control group of patients with cataracts. Data are available via ProteomeXchange with identifier PXD033153. 1589 proteins...
Source: Experimental Eye Research - April 12, 2024 Category: Opthalmology Authors: Darren Mun Yoong Choy Bryan Chin Hou Ang Sunil S Adav Zheng Yu Bo Caius Jun Shyan Goh Jin Wei Arjunan Kumaran Chua Chun Hau Nicola Yian Gan Sze Siu Kwan Leonard Wai Leon Yip Source Type: research
Aqueous humour protein dysregulation in Asian eyes with primary open angle glaucoma
Exp Eye Res. 2024 Apr 10:109887. doi: 10.1016/j.exer.2024.109887. Online ahead of print.ABSTRACTThe pathophysiology of Primary Open Angle Glaucoma (POAG) remains poorly understood. Through proteomic analysis of aqueous humour (AH) from POAG patients, we aim to identify changes in protein composition of these samples compared to control samples. High resolution mass spectrometry-based TMT6plex quantitative proteomics analysis is performed on AH samples collected from POAG patients, and compared against a control group of patients with cataracts. Data are available via ProteomeXchange with identifier PXD033153. 1589 proteins...
Source: Experimental Eye Research - April 12, 2024 Category: Opthalmology Authors: Darren Mun Yoong Choy Bryan Chin Hou Ang Sunil S Adav Zheng Yu Bo Caius Jun Shyan Goh Jin Wei Arjunan Kumaran Chua Chun Hau Nicola Yian Gan Sze Siu Kwan Leonard Wai Leon Yip Source Type: research
Dropless After Cataract Surgery (DACS) for patients with difficulties using eye drops
Eye, Published online: 12 April 2024; doi:10.1038/s41433-024-03055-8Dropless After Cataract Surgery (DACS) for patients with difficulties using eye drops (Source: Eye)
Source: Eye - April 12, 2024 Category: Opthalmology Authors: Johannes Birtel Guy Mole Sher A. Aslam Peter Charbel Issa Source Type: research
Atypical phacolytic glaucoma diagnosed by biometry and anterior segment optical coherence tomography (OCT) in a patient with CMV anterior uveitis
CONCLUSION: This is the first time that we image and document the phacolytic nature of a natural lens. Our patient did not have the typical clinical presentation and was differentially diagnosed with biometry SS-OCT and confirmed by anterior segment SD-OCT.PMID:38602030 | DOI:10.1177/11206721241246816 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 11, 2024 Category: Opthalmology Authors: Efthymios Karmiris Evangelia Papakonstantinou Konstantinos Tsiripidis Panagiotis Stavrakas Ioannis Giannakis Evangelia Chalkiadaki Source Type: research
Epidemiological, Clinical, and Therapeutic Profile of Uveitis in Multiple Sclerosis: A Multicenter Study
CONCLUSION: MS-associated uveitis occurs most frequently before the diagnosis of relapsing-remitting MS in the form of panuveitis or intermediate uveitis, which is mildly inflammatory and whose main complications are macular edema, cataract and venous vasculitis. Despite their chronicity, these uveitis cases have a good visual prognosis and teriflunomide appears to have a positive effect on progression.PMID:38602890 | DOI:10.1080/09273948.2024.2337839 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 11, 2024 Category: Allergy & Immunology Authors: R Fitoussi P Gascon D Denis T Mathis N Tieul é C Schneider-Rouhaud R Attia T David N Stolowy Source Type: research
The generation and characterization of a transgenic zebrafish line with lens-specific Cre expression
CONCLUSIONS: We established a zTg(cryaa:Cre-cryaa:EGFP) zebrafish line that can specifically express an active Cre recombinase in lens tissues. This transgenic zebrafish line can be used as a tool to specifically manipulate a gene in zebrafish lenses.PMID:38601019 | PMC:PMC11006009 (Source: Molecular Vision)
Source: Molecular Vision - April 11, 2024 Category: Molecular Biology Authors: Xuyan Peng Xiaolin Jia Guohui Shang Mengjiao Xue Mingjun Jiang Dandan Chen Fengyan Zhang Yanzhong Hu Source Type: research
Rupture of a posterior polar cataract after peribulbar block
Can J Ophthalmol. 2024 Apr 8:S0008-4182(24)00075-9. doi: 10.1016/j.jcjo.2024.03.008. Online ahead of print.NO ABSTRACTPMID:38604238 | DOI:10.1016/j.jcjo.2024.03.008 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - April 11, 2024 Category: Opthalmology Authors: David Z Chen David J Hernstadt Hazel A Lin Soon-Phaik Chee Source Type: research
Replacing the postoperative week 1 visit after routine phacoemulsification with a telephone consult
CONCLUSIONS: These results suggest that replacing the POW1 visit with a nurse-conducted telephone consult for patients who have undergone uncomplicated phacoemulsification surgery and had a normal POD1 consultation is safe.PMID:38604239 | DOI:10.1016/j.jcjo.2024.03.015 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - April 11, 2024 Category: Opthalmology Authors: Jane S Lim Shayne S Tan Yi Lin Yeo Merrelynn Hong Alvin W J Teo Yi Fang Lee Daniel S W Ting Tin Aung Rahat Husain Source Type: research
Atypical phacolytic glaucoma diagnosed by biometry and anterior segment optical coherence tomography (OCT) in a patient with CMV anterior uveitis
CONCLUSION: This is the first time that we image and document the phacolytic nature of a natural lens. Our patient did not have the typical clinical presentation and was differentially diagnosed with biometry SS-OCT and confirmed by anterior segment SD-OCT.PMID:38602030 | DOI:10.1177/11206721241246816 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 11, 2024 Category: Opthalmology Authors: Efthymios Karmiris Evangelia Papakonstantinou Konstantinos Tsiripidis Panagiotis Stavrakas Ioannis Giannakis Evangelia Chalkiadaki Source Type: research
Prices and complications in hospital-based and freestanding surgery centers
CONCLUSIONS: The higher prices charged in HOPDs for the 3 ambulatory procedures were not balanced by better quality-as measured by rates of procedural complications-compared with procedures performed in nonhospital ASCs.PMID:38603532 | DOI:10.37765/ajmc.2024.89529 (Source: The American Journal of Managed Care)
Source: The American Journal of Managed Care - April 11, 2024 Category: Health Management Authors: James C Robinson Christopher M Whaley Sanket S Dhruva Source Type: research
Visual supplementation is an effective tool in cataract surgery counselling by eye-care practitioners
CONCLUSION: Pictorial aids add to the repository of tools available to eye-care practitioners and are low-cost, easy to implement, and can effectively augment existing preoperative counselling processes to ensure accurate and effective preoperative counselling of patients.PMID:38603893 | DOI:10.1016/j.jfo.2024.104175 (Source: Journal Francais d Ophtalmologie)
Source: Journal Francais d Ophtalmologie - April 11, 2024 Category: Opthalmology Authors: W T Chan D Wu B X H Lim R Du P Jeyabal X L Ng T I Nabhan D K-A Lim F Stapleton C H L Lim Source Type: research
Epidemiological, Clinical, and Therapeutic Profile of Uveitis in Multiple Sclerosis: A Multicenter Study
CONCLUSION: MS-associated uveitis occurs most frequently before the diagnosis of relapsing-remitting MS in the form of panuveitis or intermediate uveitis, which is mildly inflammatory and whose main complications are macular edema, cataract and venous vasculitis. Despite their chronicity, these uveitis cases have a good visual prognosis and teriflunomide appears to have a positive effect on progression.PMID:38602890 | DOI:10.1080/09273948.2024.2337839 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 11, 2024 Category: Allergy & Immunology Authors: R Fitoussi P Gascon D Denis T Mathis N Tieul é C Schneider-Rouhaud R Attia T David N Stolowy Source Type: research
