Couching of cataractous lens in microphthalmic eyes with irido-fundal coloboma: revisiting the historical technique
ConclusionCouching of cataractous lens is an effective and safe method in microphthalmic eyes with irido-fundal coloboma as last resort procedure, where no other surgical procedure may work. It provides an ambulatory gain of visual acuity in previously non-ambulatory subjects. Corneal measurements help in determining the subset of patients where couching offers viable option. (Source: International Ophthalmology)
Source: International Ophthalmology - April 25, 2024 Category: Opthalmology Source Type: research
Comparison of baseline cataract rates in AB and TL wildtype zebrafish strains
In this study, we compared the baseline cataract rate between two commonly used wildtype laboratory strains, AB and TL, and also an outbred transgenic line with mCherry reporter. We assessed a total of 805 lens images of fish at 4 days post-fertilisation for cataracts and scored each cataract observed as mild, moderate or severe. We found that the AB strain had a cataract rate of 16.2%, TL had 8.9%, and mCherry had 0.7% and these rates were significantly different. We found that TL strain had a lower rate of mild cataracts than AB fish, however, the rate of moderate and severe phenotypes in the AB and the TL strain was sim...
Source: Experimental Eye Research - April 24, 2024 Category: Opthalmology Authors: Bibek Khatiwada Johanna L Jones Duran Zhao Robert J Gasperini Bennet J McComish Kathryn P Burdon Source Type: research
Metabolomic Profiling of the Aqueous Humor in Patients with Pediatric Cataract
Exp Eye Res. 2024 Apr 22:109906. doi: 10.1016/j.exer.2024.109906. Online ahead of print.ABSTRACTPediatric cataract, including congenital and developmental cataract, is a kind of pediatric vision-threatening disease with extensive phenotypic heterogeneity and multiple mechanisms. We aimed to investigate the metabolite profile of aqueous humor (AH) in patients with pediatric cataracts, and identify underlying mutual correlations between differential metabolites. Metabolomic profiles of AH were analyzed and compared between pediatric cataract patients (n=33) and age-related cataract patients without metabolic diseases (n=29),...
Source: Experimental Eye Research - April 24, 2024 Category: Opthalmology Authors: Hui Chen Yinglin Yu Leyi Hu Xiaohang Wu Lixia Luo Haotian Lin Yizhi Liu Zhenzhen Liu Source Type: research
Comparison of baseline cataract rates in AB and TL wildtype zebrafish strains
In this study, we compared the baseline cataract rate between two commonly used wildtype laboratory strains, AB and TL, and also an outbred transgenic line with mCherry reporter. We assessed a total of 805 lens images of fish at 4 days post-fertilisation for cataracts and scored each cataract observed as mild, moderate or severe. We found that the AB strain had a cataract rate of 16.2%, TL had 8.9%, and mCherry had 0.7% and these rates were significantly different. We found that TL strain had a lower rate of mild cataracts than AB fish, however, the rate of moderate and severe phenotypes in the AB and the TL strain was sim...
Source: Experimental Eye Research - April 24, 2024 Category: Opthalmology Authors: Bibek Khatiwada Johanna L Jones Duran Zhao Robert J Gasperini Bennet J McComish Kathryn P Burdon Source Type: research
Metabolomic Profiling of the Aqueous Humor in Patients with Pediatric Cataract
Exp Eye Res. 2024 Apr 22:109906. doi: 10.1016/j.exer.2024.109906. Online ahead of print.ABSTRACTPediatric cataract, including congenital and developmental cataract, is a kind of pediatric vision-threatening disease with extensive phenotypic heterogeneity and multiple mechanisms. We aimed to investigate the metabolite profile of aqueous humor (AH) in patients with pediatric cataracts, and identify underlying mutual correlations between differential metabolites. Metabolomic profiles of AH were analyzed and compared between pediatric cataract patients (n=33) and age-related cataract patients without metabolic diseases (n=29),...
Source: Experimental Eye Research - April 24, 2024 Category: Opthalmology Authors: Hui Chen Yinglin Yu Leyi Hu Xiaohang Wu Lixia Luo Haotian Lin Yizhi Liu Zhenzhen Liu Source Type: research
Sensors, Vol. 24, Pages 2700: Compound Acoustic Radiation Force Impulse Imaging of Bovine Eye by Using Phase-Inverted Ultrasound Transducer
In this study, the entire internal ocular structure of a bovine eye was visualized in an ex vivo environment using the compound acoustic radiation force impulse (CARFI) imaging scheme based on the phase-inverted ultrasound transducer (PIUT). In the proposed method, the aperture of the PIUT is divided into four sections, and the PIUT is driven by the out-of-phase input signal capable of generating split-focusing at the same time. Subsequently, the compound imaging technique was employed to increase signal-to-noise ratio (SNR) and to reduce displacement error. The experimental results demonstrated that the proposed technique...
Source: Sensors - April 24, 2024 Category: Biotechnology Authors: Gil Su Kim Hak Hyun Moon Hee Su Lee Jong Seob Jeong Tags: Article Source Type: research
An analysis of the factors involved in IOL decentration after phacoemulsification using CASIA 2 anterior segment optical coherence tomography
ConclusionGreater crystalline lens diameter was associated with greater decentration and with greater ITS. Day-one IOL decentration seems to be the main determinant of final IOL decentration. (Source: International Ophthalmology)
Source: International Ophthalmology - April 24, 2024 Category: Opthalmology Source Type: research
Comparison of short-term clinical outcomes of a diffractive trifocal intraocular lens with phacoemulsification and femtosecond laser assisted cataract surgery
To evaluate short-term visual and refractive outcomes after implantation of a diffractive trifocal intraocular lens (IOL) in cataract patients with phacoemulsification (PHACO) and femtosecond laser assisted ca... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - April 24, 2024 Category: Opthalmology Authors: Haokun Qu, Adilamu Abulimiti, Jianheng Liang, Suowang Zhou, Zheming Wu, Yun Chen, Ruihong Ju, Zheng Wang, Rong Xu and Xu Chen Tags: Research Source Type: research
A spontaneous hyperglycaemic cynomolgus monkey presents cognitive deficits, neurological dysfunction and cataract
This study first reported cognitive deficits in a spontaneous hyperglycaemia NHPs, which might provide evidence to use macaque as a promising model for translational research in diabetes and neurological complications.PMID:38650114 | DOI:10.1111/1440-1681.13863 (Source: Clinical and Experimental Pharmacology and Physiology)
Source: Clinical and Experimental Pharmacology and Physiology - April 23, 2024 Category: Drugs & Pharmacology Authors: Hongdi Huang Jianglin Pu Yufang Zhou Yang Fan Yali Zhang Yanling Li Yangzhuo Chen Yun Wang Xiaomei Yu Bulgin Dmitry Zhu Zhou Jianhong Wang Source Type: research
Vision Development in a Hallermann-Streiff Case with Bilateral Severe Microphthalmia, Cataract and Extensive Retinal Folds
Klin Monbl Augenheilkd. 2024 Apr;241(4):506-509. doi: 10.1055/a-2215-4293. Epub 2024 Apr 23.NO ABSTRACTPMID:38653282 | DOI:10.1055/a-2215-4293 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Mouna Abdulghafor Francis Munier Christina Stathopoulos Source Type: research
Real-World Clinical Results with the Hoya Vivinex Impress Intraocular Lens with Enhanced Depth of Focus
CONCLUSION: Cataract surgery with Hoya Vivinex Impress IOL implantation revealed good distance and intermediate vision and, in some patients, functional near vision as well as a high patient satisfaction.PMID:38653291 | DOI:10.1055/a-2220-0620 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Tamer Tandogan Arnas Urbonavicius Marco Langenegger David Goldblum Christoph Tappeiner Source Type: research
Patient-Reported Outcome Measures (PROMs) with Refractive and Diffractive Extended Depth of Focus (EDOF) Intraocular Lenses
CONCLUSIONS: With both types of EDOF-IOLs, the majority of patients could perform most of their daily activities without spectacles, except reading, and were highly satisfied with their IOLs. Patients with diffractive Zeiss AT LARA EDOF-IOLs were more likely to accomplish unaided near-range visual tasks; however, they were also at a higher risk of experiencing glares or halos at night.PMID:38653290 | DOI:10.1055/a-2211-8796 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Shalini Banerjee Claude Kaufmann Chiara Tinner Katja Iselin Christoph Andreas Amstutz Ying-Yu Melody Hedinger Martin K Schmid Michael Thiel Source Type: research
Silicone Oil Tamponade for Therapy of Primary Retinal Detachment in Patients Who Live at High Altitudes
CONCLUSION: PPV with SO injection seems to be a safe and efficient surgical approach in the treatment of primary uncomplicated RRD in patients living at high altitudes and was associated with good anatomical and functional outcome in our series. However, the need for a follow-up surgery to remove SO should be weighed in these cases.PMID:38653297 | DOI:10.1055/a-2233-0971 (Source: Klinische Monatsblatter fur Augenheilkunde)
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Tim Beltraminelli Quentin Hessler Theodor Stappler Jelena Potic Thomas J Wolfensberger Lazaros Konstantinidis Source Type: research
Influence of Post-radiation Ocular Surface Disorder on Ocular Surgery: A Case Report and Review of the Literature
CONCLUSION: The continuous worsening of clinical symptoms of the disorder of the ocular surface after proton beam radiotherapy can be the result of a post-radiation syndrome. Gradual expansion of ischemia, vasculitis, and inflammatory mediators compresses the retinal tissue, leading to recurrent macular edema as well as to secondary glaucoma and corneal decompensation. Band keratopathy is occasionally noted and seems to result from severe post-radiation disorder of the ocular surface. However, PKP would typically be indicated in cases of corneal perforation, uncontrolled infectious keratitis, or for improving vision in the...
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Driton Gjukaj Ilir Morina Christophe Valmaggia Dagmar Ammann Margarita G Todorova Source Type: research
A spontaneous hyperglycaemic cynomolgus monkey presents cognitive deficits, neurological dysfunction and cataract
This study first reported cognitive deficits in a spontaneous hyperglycaemia NHPs, which might provide evidence to use macaque as a promising model for translational research in diabetes and neurological complications.PMID:38650114 | DOI:10.1111/1440-1681.13863 (Source: Clinical and Experimental Pharmacology and Physiology)
Source: Clinical and Experimental Pharmacology and Physiology - April 23, 2024 Category: Drugs & Pharmacology Authors: Hongdi Huang Jianglin Pu Yufang Zhou Yang Fan Yali Zhang Yanling Li Yangzhuo Chen Yun Wang Xiaomei Yu Bulgin Dmitry Zhu Zhou Jianhong Wang Source Type: research
