Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Primary Hypertension: The Unseen Risk For Healthy People
Conclusion
In conclusion, even the healthiest individuals can develop primary hypertension, a condition that affects a significant portion of the U.S. adult population. With its roots often hidden in our genetic makeup and influenced by various lifestyle factors, hypertension can quietly disrupt our wellbeing, earning its nickname as the “silent killer.”
Real-life experiences, such as Martin Cassels’, highlight that maintaining an active, healthy lifestyle doesn’t render one immune to this condition. However, it underscores the importance of regular health check-ups and the value of a second o...
Source: The EMT Spot - July 13, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
A Throbbing Sign Of A Vitamin D Deficiency
Diseases linked to vitamin D deficiency include cardiovascular disease, diabetes and cancer. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - July 13, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Nutrition Source Type: blogs
Reviewing Efforts to Use Cells and Scaffolds to Regenerate the Heart
The heart is one of the least regenerative tissues in the body. Damage resulting from loss of blood flow during a heart attack leads to scarring and loss of function, rather than any meaningful degree of regeneration. While preventing the atherosclerosis that causes occlusion of blood vessels is the most desirable goal, finding ways to repair a damaged heart is also a high priority for the research community. Many groups have worked towards regenerative therapies based on delivery of cells and scaffolding material, even layers of artificial tissue made by combining the two, but progress has been frustratingly slow.
...
Source: Fight Aging! - July 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Angiotensin II Receptor Blockers (ARBs) For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
Cardiovascular disease (CVD) has become a leading cause of death globally, necessitating the adoption of preventive measures, early detection, and effective management strategies.
Hypertension, a significant risk factor for CVD, requires active management to mitigate associated risks.
Angiotensin II Receptor Blockers (ARBs) have emerged as a favored choice among healthcare professionals due to their effectiveness and unique benefits.
ARBs offer several advantages compared to other blood pressure medications. They effectively control blood pressure, protect vital organs such as the heart and kidneys, ...
Source: The EMT Spot - July 11, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
The Influence of Chronic Inflammation on the Hallmarks of Aging
Chronic inflammation is a feature of aging, a continual activation of the immune response without any triggering injury or infection. Many different mechanisms contribute to this state of unresolved inflammatory signaling: the accumulation of senescent cells and the senescence-associated secretory phenotype (SASP); mitochondrial dysfunction leading to mislocalized mitochondrial DNA that triggers an innate immune reaction; signaling from visceral fat cells in those who are overweight; changes in the gut microbiome and intestinal barrier that allow microbes and microbial metabolites to provoke the immune system; and so on an...
Source: Fight Aging! - July 11, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
ACE Inhibitors For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion
In conclusion, the rising utilization of blood pressure medications reflects a growing awareness of the importance of managing hypertension for overall health.
ACE inhibitors, among other drug classes, are widely used due to their effectiveness in lowering blood pressure and providing additional benefits for heart and kidney health.
It’s essential to consult your doctor before starting or adjusting ACE inhibitor treatment to ensure personalized care and monitor for potential side effects or drug interactions.
Taking ACE inhibitors as prescribed, following consistent dosing schedules, and attend...
Source: The EMT Spot - July 9, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Fight Aging! Newsletter, July 10th 2023
In conclusion, the examination of the GBA can aid in understanding the etiology and development of NDs, which may benefit the improvement of clinical treatments for these disorders and ND interventions. This review indicates existing knowledge about the involvement of microbiota present in the gut in NDs and potential treatment options.
The Aging of the Enteric Nervous System
https://www.fightaging.org/archives/2023/07/the-aging-of-the-enteric-nervous-system/
The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome ...
Source: Fight Aging! - July 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Lipid Droplet Accumulation in Aging and Age-Related Disease
Researchers here consider dysregulation of lipid metabolism at the cellular level as an aspect of aging that causes downstream issues. Like many manifestations of aging observed in cells in aged tissues, why this happens is a matter for debate, setting aside situations such as the environment of a fatty liver or atherosclerotic plaque in which there is a localized excess of lipids to explain the overload inside cells. In a number of neurodegenerative conditions, the presence of cells loaded with lipid droplets is a prominent feature. It remains to be seen as to whether new classes of therapy under development, capable of c...
Source: Fight Aging! - July 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Oxiline Pressure 9 Pro Review: State Of The Art Blood Pressure Monitor
This article will introduce you to one such smart blood pressure monitor, the Oxiline Pressure 9 Pro. We will discuss its working, features, certifications, price, and much more below. So without further ado, let us jump into the crux of this article.
What Is Oxiline Pressure 9 Pro?
The Oxiline Pressure 9 Pro is a state-of-the-art blood pressure monitor manufactured by Oxiline LLC, a reputable company based in the USA. It is a cutting-edge device designed to measure and monitor blood pressure levels accurately.
The Oxiline Pressure 9 Pro is an upgraded version of its predecessor, the Oxiline Pressure 7 Pro, in...
Source: The EMT Spot - July 6, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs
Processed Foods Linked To Increased Blood Pressure, Study Finds
Conclusions
This groundbreaking study highlights the link between high consumption of processed foods and increased blood pressure variability, particularly at night.
The findings emphasize the crucial role of diet and lifestyle in cardiovascular health.
Interestingly, researchers noted an unexpected association: higher consumption of ultra-processed foods was linked to less variation in night-time blood pressure.
This puzzling finding suggests a need for further investigation into the effects of ultra-processed foods on our health.
In conclusion, the study underscores the importance of prioritizing unproc...
Source: The EMT Spot - July 4, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Study Uncovers: Brushing Teeth Twice Daily Reduces Heart Disease Risk
Conclusion
The study came full circle, offering an emphatic conclusion.
While a morning brush is a good start, brushing before bedtime takes the crown when it comes to preventing heart diseases.
The act of brushing your teeth, so mundane yet so essential, emerges as a key soldier in the battle against heart disease.
The findings beckon us to look at our toothbrushes differently – as tools of preventative care rather than just instruments of oral hygiene.
The message is clear – taking care of our teeth could mean taking care of our hearts.
After all, our health, as this study suggests, is a...
Source: The EMT Spot - July 4, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
Drugs Vs. Digital Therapeutics – A Digital Symbiosis
In conclusion, it’s not about Drugs vs DTx. It’s about Drugs & DTx, leveraging the strengths of both for maximal benefits.
The post Drugs Vs. Digital Therapeutics – A Digital Symbiosis appeared first on The Medical Futurist. (Source: The Medical Futurist)
Source: The Medical Futurist - July 4, 2023 Category: Information Technology Authors: Andrea Koncz Tags: E-Patients Future of Pharma Personalized Medicine Telemedicine & Smartphones DTx digital therapeutics prescription apps Source Type: blogs
Oxiline Pressure 7 Pro Review: The Best Basic Blood Pressure Monitor?
If you are new to at-home blood pressure monitoring and planning to purchase one, then check out this review of the Oxiline Pressure 7 Pro. Happy reading!
Oxiline Pressure 7 Pro
Features:
VIBRA technology detects even the slightest arterial wall vibrations thanks to the accuracy of its patented VIBRA T7 sensor.
Easy color reference indicator to compare your reading with the World Health Organization color codes of various blood pressure levels.
Fully automatic and easy to operate with FDA clearance and world-class standards in accuracy.
It has a high-contrast LED display that features bright and ...
Source: The EMT Spot - July 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs
Fight Aging! Newsletter, July 3rd 2023
In this study, cultured adipose-derived stem cells (ASCs) were derived from subcutaneous white adipose tissue isolated from mice fed a normal diet. We performed senescence-associated-β-galactosidase (SA-β-gal) staining, real-time PCR, and Western blot to evaluate the levels related to cellular senescence markers.
The mRNA expression levels of senescence markers were significantly increased in the later passages of ASCs. We show that light activation reduced the expression of senescent genes, and SA-β-Gal in all cells at passages. Moreover, the light-activated ASCs-derived exosomes decrease the expression of senes...
Source: Fight Aging! - July 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
