What is SCAPE in Cardiovascular Medicine?
SCAPE is an acronym for sympathetic crash acute pulmonary edema, which can typcially occur in Pickering syndrome with renal artery stenosis [1]. Another term for transient acute pulmonary edema which occurs in renal artery stenosis is flash pulmonary edema. SCAPE is the extreme end of the spectrum of acute pulmonary edema and needs urgent management in the emergency room [2]. Excessive release of catecholamines may increase the permeability of pulmonary capillaries and facilitate flash pulmonary edema [3]. Endothelial dysfunction secondary to excessive activity of renin-angiotenisn-aldosterone axis, impaired synthesis of ...
Source: Cardiophile MD - November 12, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Weekly Roundup – November 11, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week.
American Telemedicine Association Leaps Into Privacy and AI Policies. Andy Oram talked to Kyle Zebley about how the ATA aims to be the voice of the telehealth community, in large part through its recently released sets of governing principles for AI and data privacy. Read more…
Effective Epic Application Management and Go-Live. Jennifer Stemmler ...
Source: EMR and HIPAA - November 11, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs
The Immune System Mediates Some of the Benefits of Exercise
It is uncontroversial to point out that exercise is good for long-term health. It slows aging, reduces risk of age-related disease, reduces mortality. A mountain of evidence supports these assertions, both animal studies demonstrating causation, and any number of large human studies showing correlation. Exercise, like the practice of calorie restriction, produces sweeping changes in the operation of metabolism. Near everything is different, both in the short term following exercise, and over the long term when looking at differences between the biochemistry of a fit individual versus that a sedentary individual. This can m...
Source: Fight Aging! - November 10, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Specific Inhibition of miR-206 Activity Boosts CXCR4 Expression to Suppress the Development of Atherosclerosis
Researchers here find an approach to selective upregulation of CXCR4 that acts to suppress the development of atherosclerosis in a mouse model. It is a small molecule treatment, so may well make its way into further development. Like all such treatments, however, it will likely prove to have little effect on established atherosclerotic plaques. It remains to be seen as to whether the research and development community can bring effective means of reversal of atherosclerosis to the clinic in the years ahead. Efforts to produce therapies capable of reversal have to date near all focused on enhancing reverse cholesterol trans...
Source: Fight Aging! - November 9, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Role of Senescent Cells in Age-Related Skeletal Diseases
Compelling evidence obtained from many studies in mice show that the accumulation of senescent cells with age is a major contributing factor in all of the common, inflammatory age-related conditions: cardiovascular disease, dementia, degeneration of bone tissue, and so forth. Senescent cells are created throughout life, mostly as somatic cells reach the Hayflick limit on replication, but accumulate in later life in large part because the immune system falters in its clearance of senescent cells. It still performs this function, but less efficiently, and the balance between creation and destruction of senescent cells tips t...
Source: Fight Aging! - November 8, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Kento Health Raises $4.1 Million CAD to Bring AI to Cardiovascular Care
Dialogue Alumni’s New Startup is Gearing up to Strike Hard in the Battle Against the Leading Cause of Death
Montréal-based healthtech startup Kento Health has closed a $4.1 million CAD ($3 million USD) pre-seed financing round.
The round was led by Boreal Ventures and N49P and saw participation from Broom Ventures, Graphite Ventures, and several other strategic angel investors as well as an undisclosed US-based medical institution. Kento claims it is poised to make a substantial impact in the fight against the world’s leading cause of death by using technology like artificial intelligence (AI).
“This funding not...
Source: EMR and HIPAA - November 8, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alex Norman Boreal Ventures Broom Ventures David Charbonneau Dialogue Health Graphite Ventures Health IT Funding Health IT Fundings Health IT Investment Jonah Davies Kento Kento Health Max Leca Source Type: blogs
3D Printing In Medicine And Healthcare – The Ultimate List
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. See the impressive list of 3D-printed healthcare materials and medical equipment below!
How does 3D printing in medicine work?
3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained in our article on bioprinting here.
As technology evolves, researchers work on various solutions. For example, engineers from the University of Buffalo have ...
Source: The Medical Futurist - November 7, 2023 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine 3d printed biomaterial tissue engineering Video bioprinting GC1 Innovation Source Type: blogs
Fight Aging! Newsletter, November 6th 2023
This study aimed to gather valuable insights from pharmaceutical experts and healthcare practitioners regarding the potential and challenges of translating senolytic drugs for treatment of vascular aging-related disorders. This study employed a qualitative approach by conducting in-depth interviews with healthcare practitioners and pharmaceutical experts. Participants were selected through purposeful sampling. Thematic analysis was used to identify themes from the interview transcripts. A total of six individuals were interviewed, with three being pharmaceutical experts and the remaining three healthcare practitioners.
...
Source: Fight Aging! - November 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Accelerated Epigenetic Age and Cardiovascular Risk Factors
Epigenetic patterns determine the behavior of a cell, and change constantly in response to cell state and the surrounding tissue environment. Epigenetic state can be used to measure biological age, the epigenetic clock. When an epigenetic clock indicates an age older than chronological age, that is referred to as epigenetic age acceleration. While the clocks are not fully understood in detail, it is thought that the specific epigenetic changes measured are reflective of the burden of cell and tissue damage and dysfunction that causes aging. This acceleration has been shown to correlate with risk and status of a number of a...
Source: Fight Aging! - November 2, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Reviewing the Role of Insulin in Aging
The relationship between insulin metabolism and aging is one of the most studied areas of the field, with decades of researchers putting in time to deepen the understanding of the web of interactions surrounding insulin. Yet this has failed to lead to any practical outcome when it comes to slowing or reversing aging. Researchers now have an incrementally better idea as to why obesity, metabolic syndrome, and type 2 diabetes shorten life and worsen health, but that was well understood to be the case well prior to the advent of modern biotechnology.
Experimental studies in animal models of aging such as nematodes, f...
Source: Fight Aging! - October 31, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Gingivitis Bacteria Causes Harms in the Heart, Impairing Already Poor Recovery from Heart Attack
Inflammatory periodontal disease is caused by a specific bacterial species. The bacteria can use damaged gums to enter the bloodstream. It is thought that its ability to provoke inflammation can then contribute to cardiovascular disease and dementia, though the size of the effect is up for debate. Along these lines, researchers here show that periodontal bacteria can worsen the consequences of a heart attack, impairing the already limited ability of the heart to regenerate and restore function following injury.
Heart attacks occur when blood flow in the coronary arteries is blocked, resulting in an inadequate supp...
Source: Fight Aging! - October 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Bonus Features – October 29, 2023 – 66% of patients prefer email or text for reminders about medical bills, 94% of clinicians said lack of timely access to insights within EHR impacts patient care, and 28 more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
CMMI released the 2022 performance results for the direct contracting value-based care model, which has since been redesigned and renamed the ACO REACH Model. All told, participating entities achieved net savings of more t...
Source: EMR and HIPAA - October 29, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 1upHealth ACO REACH AGS Health Avenda Health Bluefin California HHS Carestream Dental CB Insights Cedar Gate Technologies CMMI CORE eClinicalWorks Fivetran Found Freshpaint FutureRx GSR Ventures Healthcare Source Type: blogs
Fight Aging! Newsletter, October 30th 2023
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.
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Source: Fight Aging! - October 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Sizable Mortality Risk Differences for Healthy versus Unhealthy Lifestyles in Later Life
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.
Link: https://doi.org/10.1186/s12877-023-04247-9 (Source: Fight Aging!)
Source: Fight Aging! - October 27, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Higher Serum Klotho Correlates with Lower Systemic Inflammation
The objective of this research is to determine the linkage between soluble Klotho (S-Klotho) level and systemic immune-inflammation index (SII).
Eligible participants with complete information of S-Klotho level and SII were selected from the National Health and Nutrition Examination Surveys (NHANES). Subsequently, weighted multivariate linear regression and subgroup analysis were carried out to evaluate the association. Totally, 11,108 adults with complete data on S-Klotho level, SII and other important covariates were included in final analysis. Multivariate liner regression revealed that high level of S-Klotho wa...
Source: Fight Aging! - October 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
