Best Blood Pressure Monitors During Pregnancy
Conclusion Pregnancy is a period in a woman’s life where health monitoring becomes crucial, and one key aspect that requires regular monitoring is blood pressure. Elevated blood pressure during pregnancy can lead to severe complications, such as preeclampsia, which poses risks to both the mother and the unborn child. This guide provides comprehensive information on selecting the best blood pressure monitor during pregnancy, considering the vast array of options available in the marketplace. It highlights the essential features to consider, such as accuracy, ease of use, and additional features like irregu...
Source: The EMT Spot - August 28, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Longevity-Associated Variant of BPIFB4 Reduces Heart Disease Severity
Few human longevity-associated gene variants are replicated in multiple patient populations. One of those is a variant of BPIFB4, that appears to improve immune function and lower inflammation by adjusting the behavior of macrophage cells of the innate immune system. Delivering the variant to mice using a gene therapy has similar effects. It may well operate via other mechanisms as well, however. Few proteins in a living cell turn out to have only one purpose. In today's open access paper, researchers report that the BPIFB4 variant reduces the severity of coronary artery disease in humans and mice. Delivering the va...
Source: Fight Aging! - August 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Navigating Correlation and Causation with Life Sciences in the Age of AI
The following is a guest article by Alex Long, Head of Life Sciences Sales Strategy at Dell Technologies In science, avoiding correlation without causation is a cornerstone of research methodology. This fundamental principle ensures that scientific conclusions are grounded in evidence rather than coincidental associations. However, as we venture into the Artificial Intelligence (AI) age, a new challenge emerges – that of “Correlation, not Creation.” A classic example highlighting the distinction between correlation and causation is the seemingly bizarre connection between ice cream sales and swimming acci...
Source: EMR and HIPAA - August 24, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AI Hallucination Alex Long Correlation vs Causation Dell Technologies Generative AI Healthcare Scene Featured Human Source Type: blogs

Lipid Metabolism in Age-Related Disease
In this age of excess calories, in which a large proportion of the population is significantly overweight, research into lipid metabolism in the context of aging tends overlap with research into lipid metabolism in the context of obesity. People of normal weight still undergo complex changes in lipid metabolism and lipid transport throughout the body with age, however. These lead to prominent, important issues such as atherosclerosis, localized excesses of cholesterol and associated lesions in the arterial walls, for example. Looking at these conditions through the lens of lipid metabolism is looking at just one part of a ...
Source: Fight Aging! - August 23, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Bonus Features – August 20, 2023 – Healthcare orgs only use 57% of their data to drive decision-making, digital health is well represented on the Inc. 5000 list, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News The annual Inc. 5000 list is live. Digital health companies on the list include AngelEye Health, Authenticx, DAS Health, FarmboxRX, ixlayer, Mytonomy, Reveleer, TigerConnect, TimelyCare, Valenz Health, Veda, and Vytalize He...
Source: EMR and HIPAA - August 20, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 1upHealth 4medica Accelecom AliveCor Anahi Santiago AngelEye Health Authenticx AVIA Azalea Health Boston Children's Hospital C3HIE Center for Virtual Care Value and Equity Cerner Cerner CommunityWorks Christiana Source Type: blogs

Weekly Roundup – August 19, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week. Helping Children With Gamified Interactive Physiotherapy. Psychiatrist Dr. Geoff Frost struggled to encourage pediatric patients with spinal muscular atrophy to do their necessary exercises. As he explained to Colin Hung, that’s why Raft Digital Therapeutics created a game called Cloud Bazaar to captures a child’s movement as a way to advance...
Source: EMR and HIPAA - August 19, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs

Associations Between the Lipidome and Epigenetic Aging
The body contains hundreds of different types of lipid molecules, participating in cellular metabolism in ways that are just as complex and relevant to health as the activities of other biomolecules. In the context of aging, this broad range of lipids are perhaps understudied in comparison to levels and roles of proteins and patterns of gene expression. The situation is much the same, however: researchers can readily and cost-effectively amass a vast amount of data, but the analysis of this data lags far behind the accumulation of ever more and ever larger omics databases. It is ever unclear as to whether any particular as...
Source: Fight Aging! - August 18, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Raised Remnant Cholesterol Level Correlates with Frailty
Remnant cholesterol refers to circulating cholesterol in the bloodstream that is not attached to LDL transport particles coming from the liver or HDL transport particles going to the liver. The remnant is attached to some mix of VLDL and IDL particles that serve much the same purpose as LDL particles, or incorporated into much larger chylomicron transporters that carry dietary lipids from the intestines throughout the body. Researchers have noted that remnant cholesterol appears to contribute to cardiovascular risk, speeding the progression of atherosclerosis and increasing the risk of stroke and heart attack. It is...
Source: Fight Aging! - August 16, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Survivors of Nuclear Weapon Use in Early Life Exhibit Accelerated Immune Aging in Late Life
It probably strains the meaning of the term to call the aftermath of the use of nuclear weapons at the end of the Second World War a natural experiment, but nonetheless there has been considerable study of survivors from those events and their health relative to control populations in other parts of Japan. Irradiation is known to produce what is effectively accelerated aging in the context of cancer treatment, producing an increased burden of senescent cells that then ensure the later course of health for survivors is worse than would otherwise be the case, absent both cancer and treatment. In the case of exposure to radia...
Source: Fight Aging! - August 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Cuff Size Impacts Blood Pressure Measurement Accuracy – The Study
Conclusion The journey through the nuances of blood pressure measurements unveils a pivotal lesson: individuality matters. The convenience of a one-size-fits-all approach, while appealing, may not stand up to the rigorous demands of health accuracy. Each person’s uniqueness, from their arm size to their health conditions, necessitates a tailored approach, especially when it comes to something as vital as blood pressure readings. Yet, the responsibility doesn’t just lie with the medical professionals. As readers, as individuals, there’s a clarion call for proactivity. Being informed, asking quest...
Source: The EMT Spot - August 10, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Best Blood Pressure Monitors For Large Arms
This article aims to provide comprehensive information on the best blood pressure monitors designed for larger arms.  Remember, a properly fitted monitor can lead to better tracking of your blood pressure, improved control of hypertension if you have it, and, ultimately, better cardiovascular health. Keep reading to discover the top options, what to consider when making your selection, and how to ensure you’re using your blood pressure monitor correctly for consistent, reliable readings. In addition, we delve into various other monitoring techniques suitable for those with larger arms and address some c...
Source: The EMT Spot - August 10, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Monitors Source Type: blogs

Chest pain and T wave inversion, NSTEMI?
Case submitted and written by Dr. Mazen El-Baba and Dr. Emily Austin, with edits from Jesse McLarenA 50 year-old patient presented to the Emergency Department with sudden onset chest pain that began 14-hours ago. The nurse alerted the MD because the patient was still symptomatic, diaphoretic and “looking unwell”. What do you think?      ECG interpretation: sinus rhythm, normal conduction (PR, QRS, and QTc), normal axis, delayed R-wave progression, and normal voltages. There ’s primary TWI inferiorly (aVF and III) and V6, with reciprocal tall T-wave in lead I/aVL, and a Q wave in III. The...
Source: Dr. Smith's ECG Blog - August 10, 2023 Category: Cardiology Authors: Jesse McLaren Source Type: blogs