Inhibition of Fatty Acid Oxidation Provokes Greater Regenerative Capacity in the Injured Heart
The heart is one of the least regenerative organs in the adult body, and this makes the lasting consequences of a heart attack that much worse. While the best approach to the challenge of cardiovascular disease is to find a way to reverse atheroslerosis, and thus prevent heart attacks from ever occurring, much of the focus of the research community is on improving the regenerative capacity of heart tissue. Here, researcher find a comparatively straightforward way to make cardiomyocyte cells in the heart behave more like those in developing tissue, increasing their regenerative capacity. Since the target is well defined, th...
Source: Fight Aging! - October 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
More White Matter Hyperintensities, Greater Cognitive Decline
Researchers here show that the burden of white matter hyperintensities in the brain correlates with both age and with loss of cognitive function. A white matter hyperintensity is named for its appearance in MRI images of the brain, and is an area of damaged tissue. The cause can include rupture of small blood vessels, which is increasingly common with advancing age, particularly in patients with hypertension, or forms of inflammation and scarring, often associated with leakage of the blood-brain barrier, another issue that becomes prevalent with age. These incidences of damage to the brain are individually minor, but colle...
Source: Fight Aging! - October 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Modestly Increased Physical Activity Reduces the Age-Related Increase in Blood Pressure
The difference between lesser and greater degrees of modest exercise is sizable when it comes to effects on measures of cardiovascular health, such as blood pressure. The raised blood pressure characteristic of aging and a lack of physical fitness is damaging to delicate tissues, speeds the development of atherosclerosis, and is associated with a raised risk of mortality. A sizable proportion of the mortality reduction that attends greater physical activity in later life may be mediated via effects such as lowered blood pressure.
A study sought to determine if older adults with hypertension could receive these ben...
Source: Fight Aging! - October 3, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Continued Study of Urolithin A to Improve Mitochondrial Function
Urolithin A is one of a number of compounds available as supplements that can improve mitochondrial function in older individuals. Like others, urolithin A may function by improving the mitochondrial quality control process of mitophagy, responsible for removing damaged and worn mitochondria. Mitophagy becomes less efficient with age, and this is one of the contributing factors to age-related loss of mitochondrial function and its harmful impact on tissues. Like other supplement based approaches to improving mitochondrial function, it is likely that regular exercise delivers larger gains than those demonstrated for supplem...
Source: Fight Aging! - October 2, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
This Monthly Vitamin Supplement Reduces Heart Attack Risk 19%
A monthly dose of the vitamin was found to lower the incidence of cardiovascular events, including heart attacks. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - October 1, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs
Bonus Features – October 1, 2023 – 45 Percent of patients prefer telehealth for minor but urgent issues and much more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
Surveys and Research
Nearly 30% of telehealth visits result in an in-person follow-up within three weeks, and nearly half of patients who used telehealth only did it once, according to Trilliant Health’s latest report on t...
Source: EMR and HIPAA - October 1, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Aaron Tendler Accelecom AccYouRate AdvancedMD Affirm Aiberry Akasa Amwell Apollo MD AvaSure Cedar Christine Davis Costco DAX Copilot Evidium Foresite Capital Google Cloud Gozio Health GrayMatters Health Source Type: blogs
Climbing More Than Five Flights of Stairs Daily Reduces Risk of Heart Disease!
World Heart Day greetings to all. Climbing more than five flights of stairs every day can reduce the risk of atherosclerotic cardiovascular disease by over 20% according to a study using data from the UK Biobank, published in the journal Atherosclerosis [1]. But beware, those who stop climbing has a higher risk than those who never did it! The study had over four hundred and fifty thousands adult participants. Information about climbing stairs, sociodemographic factors and lifestyle factors were collected at baseline and by a resurvey after 5 years. Median follow up period was 12.5 years. Similar results were noted for bo...
Source: Cardiophile MD - September 29, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Beyond The Hype: The Top 5 Digital Health Devices Making A Real Difference In My Life
In the digital health era, an abundance of devices promises to streamline our health and optimize every breath we take. For enthusiasts like us at The Medical Futurist, it’s a realm of fascinating trials, rigorous testing, and delightful discoveries. As Dr. Meskó and the team have experimented with over a hundred devices, we’ve had the pleasure of immersing ourselves in this tech-filled healthcare voyage. While all devices had their moments, five stood out as champions in enhancing our everyday lives and bringing the most practical benefit. Let’s see our subjective list of the top 5 digital health devic...
Source: The Medical Futurist - September 26, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Health Sensors & Trackers digital health smartwatch wearables continous glucose monitoring best digital health devices air quality Source Type: blogs
The Top 5 Digital Health Devices Making A Real Difference In A Healthy Lifestyle
In the digital health era, an abundance of devices promises to streamline our health and optimize every breath we take. For enthusiasts like us at The Medical Futurist, it’s a realm of fascinating trials, rigorous testing, and delightful discoveries. As Dr. Meskó and the team have experimented with over a hundred devices, we’ve had the pleasure of immersing ourselves in this tech-filled healthcare voyage. While all devices had their moments, five stood out as champions in enhancing our everyday lives and bringing the most practical benefit. Let’s see our subjective list of the top 5 digital health devic...
Source: The Medical Futurist - September 26, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Health Sensors & Trackers air quality digital health smartwatch wearables continous glucose monitoring best digital health devices Source Type: blogs
Fight Aging! Newsletter, September 25th 2023
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
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Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug
https://www.fightaging.org/archives/2023/09/results-from-human-clinical-trials-do-not-support-metformin-as-a-longevity-drug/
The SENS Research Fou...
Source: Fight Aging! - September 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Adaptation-Maladaptation Framework of Aging
While a great deal is known about the ways in which old tissues differ from young tissues, there remains considerable room to theorize on how exactly aging is caused and progresses. Which manifestations are causative, and which downstream consequences, which mechanisms are important, which are side-effects or diversions. Theories of aging abound, alongside frameworks intended to steer thinking about aging. We stand in the opening years of a new era of medicine, in which the first rejuvenation therapies exist or are under development, senolytics that can clear senescent cells, alongside reprogramming strategies and potentia...
Source: Fight Aging! - September 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
A Selection of Mechanisms Relevant to Atherosclerosis
Atherosclerosis is the growth of fatty lesions in blood vessel walls, leading eventually to a rupture and blockage to cause a heart attack or stroke, and along the way causing narrowing of blood vessels sufficient to lead to heart failure and dysfunction elsewhere in the body as the supply of blood to tissues is reduced. Today's paper on this topic is a little disorganized, something of a random assembly of thoughts on mechanisms relevant to the development of atherosclerosis. Atherosclerosis is the single largest cause of human mortality, and attempts to treat contributing mechanisms have so far not stopped it from being ...
Source: Fight Aging! - September 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Increased Mortality Associated with High Blood Pressure that Declines While Remaining Above the Normal Range
In conclusion, long-term BP trajectory was associated with all-cause mortality, especially CVD mortality. Keeping a stable BP over time may be an important way for CVD prevention among the elderly.
Link: https://doi.org/10.3389/fcvm.2023.1157327 (Source: Fight Aging!)
Source: Fight Aging! - September 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mitochondrial Epigenetics in Age-Related Mitochondrial Dysfunction
The hundreds of mitochondria present in every cell in the body undertake the essential duty of producing chemical energy store molecules, adenosine triphosphate (ATP), used to power the cell. With age, mitochondria become less efficient and more damaged, generating oxidative stress and triggering inflammation while producing less ATP than is optimal. This is thought to be a major contribution to degenerative aging, though as for all contributions to aging, it requires a highly targeted way to improve mitochondrial function in order to determine just how important it is. That highly targeted therapy doesn't yet exist in a u...
Source: Fight Aging! - September 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
