Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

Novel automated antifungal susceptibility testing system for yeasts based on dual-detection algorithm of turbidimetry and colorimetry
Conclusion. Given the above, it can be argued that the utilization of Fungus AST is a discretionary automated approach. More improvements are needed in Fungus AST compared to the BMD system for a wider range of clinical isolates, including different types of fungi.PMID:38440953 | DOI:10.1099/jmm.0.001811 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 5, 2024 Category: Microbiology Authors: Tingting Shen Piao Liu Dongmiao Chen Duoduo Liu Juan Fang Qian Wang Yinjuan Xu Chunjuan Tan Congrong Wang Source Type: research

< em > Candida glabrata < /em > oropharyngeal infection in a patient with oral squamous cell carcinoma after COVID-19 infection
CONCLUSION: Risk of fungal infections, such as Candida seems to be high in patients with severe COVID-19, mainly affecting the oral mucosa. However, whether they are directly attributed to COVID-19 or other surrounding factors is unknown.PMID:38361958 | PMC:PMC10864745 | DOI:10.22034/cmm.2023.345120.1478 (Source: Pain Physician)
Source: Pain Physician - February 16, 2024 Category: Anesthesiology Authors: Jalal Jafarzadeh Javad Javidnia Seyed Ali Jeddi Mahshid Vakili Mojtaba Taghizadeh Armaki Mahin Tavakoli Source Type: research

< em > Candida glabrata < /em > oropharyngeal infection in a patient with oral squamous cell carcinoma after COVID-19 infection
CONCLUSION: Risk of fungal infections, such as Candida seems to be high in patients with severe COVID-19, mainly affecting the oral mucosa. However, whether they are directly attributed to COVID-19 or other surrounding factors is unknown.PMID:38361958 | PMC:PMC10864745 | DOI:10.22034/cmm.2023.345120.1478 (Source: Pain Physician)
Source: Pain Physician - February 16, 2024 Category: Anesthesiology Authors: Jalal Jafarzadeh Javad Javidnia Seyed Ali Jeddi Mahshid Vakili Mojtaba Taghizadeh Armaki Mahin Tavakoli Source Type: research

SAR study of N'-(Salicylidene)heteroarenecarbohydrazides as promising antifungal agents
Bioorg Med Chem. 2024 Jan 24;100:117610. doi: 10.1016/j.bmc.2024.117610. Online ahead of print.ABSTRACTClinically available antifungal drugs have therapeutic limitations due to toxicity, narrow spectrum of activity, and intrinsic or acquired drug resistance. Thus, there is an urgent need for new broad-spectrum antifungal agents with low toxicity and a novel mechanism of action. In this context, we have successfully identified several highly promising lead compounds, i.e., aromatic N'-(salicylidene)carbohydrazides, exhibiting excellent antifungal activities against Cryptococcus neoformans, Candida albicans, Aspergillus fumi...
Source: Bioorganic and Medicinal Chemistry - February 2, 2024 Category: Chemistry Authors: Yi Sun Saerom Kim SeungYoun Shin Kathryn Takemura Gabriel S Matos Cristina Lazzarini Krupanandan Haranahalli Julia Zambito Ashna Garg Maurizio Del Poeta Iwao Ojima Source Type: research

A regimen based on the combination of trimethoprim/sulfamethoxazole with caspofungin and corticosteroids as a first-line therapy for patients with severe non-HIV-related pneumocystis jirovecii pneumonia: a retrospective study in a tertiary hospital
Pneumocystis jirovecii pneumonia (PJP) is a life-threatening and severe disease in immunocompromised hosts. A synergistic regimen based on the combination of sulfamethoxazole-trimethoprim (SMX-TMP) with caspof... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Hao Li, Yihe Lu, Guoxin Tian, Yongxing Wu, Tianjun Chen, Jiangwei Zhang, Nan Hu, Xiaoning Wang, Yang Wang, Lan Gao, Jinqi Yan, Linjing Zhou and Qindong Shi Tags: Research Source Type: research

Safety and efficacy of non-reduced use of caspofungin in patients with Child –Pugh B or C cirrhosis: a real-world study
ConclusionsStandard-dose of caspofungin can be safely and effectively used in patients with Child –Pugh B or C cirrhosis, and we appealed to re-assess the most suitable dosing regimen in this population to avoid a potential subtherapeutic exposure. (Source: Infection)
Source: Infection - January 24, 2024 Category: Infectious Diseases Source Type: research

18S rRNA sequencing and homology analysis of post-traumatic bloodstream infection with Saprochaete clavata (Magnusiomyces clavatus) and a case report
We present a case of bloodstream infection with Saprochaete clavata following an abdominal steel impact injury in a 52-year-old man, whose non-healing abdominal wound was also highly suspected of being caused by Saprochaete clavata. Saprochaete clavata is a very uncommon fungal pathogen. Our case is distinctive in that previous reports have typically involved immunocompromised, malignant, or leukemic patients. In contrast, our case involved a middle-aged man in good health who had ileal perforation repair for gastrointestinal perforation. Post-surgery, Saprochaete clavata was isolated from the incision exudate and blood sa...
Source: New Microbiologica - January 22, 2024 Category: Microbiology Authors: Wei Jia Guang Chen Wanxiang Li Jie Ma Xue Zhao Source Type: research