A Review of Studies on < em > Candida < /em > Species in Peninsular Malaysia
Adv Biomed Res. 2022 Nov 28;11:98. doi: 10.4103/abr.abr_3_22. eCollection 2022.ABSTRACTData on the epidemiology and the antifungal susceptibility of Candida species infections in Malaysia is still limited. The study aimed to review and compare studies reporting the prevalence of Candida species and antifungal susceptibility of Candida infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords "Candida and Malaysia." Around 19 Candida species were identified in a total of 35,608 Candida ...
Source: Biomed Res - January 20, 2023 Category: Research Authors: Humaira Farooq Tahmina Monowar Swe Swe Latt Suresh V Chinni Noor Hasliza Zainol Gokul Shankar Sabesan Source Type: research
A Review of Studies on < em > Candida < /em > Species in Peninsular Malaysia
Adv Biomed Res. 2022 Nov 28;11:98. doi: 10.4103/abr.abr_3_22. eCollection 2022.ABSTRACTData on the epidemiology and the antifungal susceptibility of Candida species infections in Malaysia is still limited. The study aimed to review and compare studies reporting the prevalence of Candida species and antifungal susceptibility of Candida infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords "Candida and Malaysia." Around 19 Candida species were identified in a total of 35,608 Candida ...
Source: Adv Data - January 20, 2023 Category: Epidemiology Authors: Humaira Farooq Tahmina Monowar Swe Swe Latt Suresh V Chinni Noor Hasliza Zainol Gokul Shankar Sabesan Source Type: research
A Review of Studies on < em > Candida < /em > Species in Peninsular Malaysia
Adv Biomed Res. 2022 Nov 28;11:98. doi: 10.4103/abr.abr_3_22. eCollection 2022.ABSTRACTData on the epidemiology and the antifungal susceptibility of Candida species infections in Malaysia is still limited. The study aimed to review and compare studies reporting the prevalence of Candida species and antifungal susceptibility of Candida infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords "Candida and Malaysia." Around 19 Candida species were identified in a total of 35,608 Candida ...
Source: Biomed Res - January 20, 2023 Category: Research Authors: Humaira Farooq Tahmina Monowar Swe Swe Latt Suresh V Chinni Noor Hasliza Zainol Gokul Shankar Sabesan Source Type: research
A Review of Studies on < em > Candida < /em > Species in Peninsular Malaysia
Adv Biomed Res. 2022 Nov 28;11:98. doi: 10.4103/abr.abr_3_22. eCollection 2022.ABSTRACTData on the epidemiology and the antifungal susceptibility of Candida species infections in Malaysia is still limited. The study aimed to review and compare studies reporting the prevalence of Candida species and antifungal susceptibility of Candida infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords "Candida and Malaysia." Around 19 Candida species were identified in a total of 35,608 Candida ...
Source: Adv Data - January 20, 2023 Category: Epidemiology Authors: Humaira Farooq Tahmina Monowar Swe Swe Latt Suresh V Chinni Noor Hasliza Zainol Gokul Shankar Sabesan Source Type: research
UDP-Galactopyranose Mutase Mediates Cell Wall Integrity, Polarity Growth, and Virulence in Fusarium graminearum
In conclusion, UGMA is an important pathogenic factor that is specific to fungi and bacteria and required for cell wall architecture, radial growth, and caspofungin tolerance, and it appears to be a promising target for antifungal agent development. IMPORTANCE The long-term use of chemical pesticides has had increasingly negative impacts on the ecological environment and human health. Low-toxicity, high-efficiency and environmentally friendly alternative pesticides are of great significance for maintaining the sustainable development of agriculture and human and environmental health. Using fungus- or microbe-specific genes...
Source: Applied and Environmental Microbiology - January 19, 2023 Category: Microbiology Authors: Shulin Cao Wenqiang Jiang Yan Shu Wei Li Yani Zhang Aixiang Zhang Huaigu Chen Source Type: research
UDP-Galactopyranose Mutase Mediates Cell Wall Integrity, Polarity Growth, and Virulence in Fusarium graminearum
In conclusion, UGMA is an important pathogenic factor that is specific to fungi and bacteria and required for cell wall architecture, radial growth, and caspofungin tolerance, and it appears to be a promising target for antifungal agent development. IMPORTANCE The long-term use of chemical pesticides has had increasingly negative impacts on the ecological environment and human health. Low-toxicity, high-efficiency and environmentally friendly alternative pesticides are of great significance for maintaining the sustainable development of agriculture and human and environmental health. Using fungus- or microbe-specific genes...
Source: Applied and Environmental Microbiology - January 19, 2023 Category: Microbiology Authors: Shulin Cao Wenqiang Jiang Yan Shu Wei Li Yani Zhang Aixiang Zhang Huaigu Chen Source Type: research
In vitro and in vivo evaluation of antifungal combinations against azole-resistant Aspergillus fumigatus isolates
In conclusion, the combination of caspofungin with azoles is a promising alternative for the treatment of azole resistant strains of Af. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - January 17, 2023 Category: Microbiology Source Type: research
Molecules, Vol. 28, Pages 933: Synthesis and Antimicrobial Activity Evaluation of Homodrimane Sesquiterpenoids with a Benzimidazole Unit
agiu
Aculina Aricu
Herein we report a feasible study concerning the synthesis and the in vitro antimicrobial activity of some new homodrimane sesquiterpenoids with a benzimidazole unit. Based on some homodrimane carboxylic acids, on their acyl chlorides and intermediate monoamides, a series of seven N-homodrimenoyl-2-amino-1,3-benzimidazoles and 2-homodrimenyl-1,3-benzimidazoles was synthesized. The syntheses involved the decarboxylative cyclization and condensation of the said acids or acyl chlorides with o-phenylendiamine and 2-aminobenzimidazole, as well as the p-TsOH-mediated cyclodehydration of the said monoacyl...
Source: Molecules - January 17, 2023 Category: Chemistry Authors: Lidia Lungu Svetlana Blaja Caleria Cucicova Alexandru Ciocarlan Alic Barba Veaceslav Kulci țki Sergiu Shova Nicoleta Vornicu Elisabeta-Irina Geana Ionel I. Mangalagiu Aculina Aricu Tags: Article Source Type: research
Cecropin D-derived synthetic peptides in the fight against Candida albicans cell filamentation and biofilm formation
The recent progressive increase in the incidence of invasive fungal infections, especially in immunocompromised patients, makes the search for new therapies crucial in the face of the growing drug resistance of prevalent nosocomial yeast strains. The latest research focuses on the active compounds of natural origin, inhibiting fungal growth, and preventing the formation of fungal biofilms. Antimicrobial peptides are currently the subject of numerous studies concerning effective antifungal therapy. In the present study, the antifungal properties of two synthetic peptides (ΔM3, ΔM4) derived from an insect antimicrobial pep...
Source: Frontiers in Microbiology - January 13, 2023 Category: Microbiology Source Type: research
Viruses, Vol. 15, Pages 197: Polymycovirus Infection Sensitizes Aspergillus fumigatus for Antifungal Effects of Nikkomycin Z
. Stevens
Infection with Aspergillus fumigatus polymycovirus 1 (AfuPmV-1) weakens resistance of Aspergillus fumigatus common reference strain Af293 biofilms in intermicrobial competition with Pseudomonas aeruginosa. We compared the sensitivity of two infected and one virus-free Af293 strains to antifungal drugs. All three were comparably sensitive to drugs affecting fungal membranes (voriconazole, amphotericin) or cell wall glucan synthesis (micafungin, caspofungin). In contrast, forming biofilms of virus-free Af293 were much more resistant than AfuPmV-1-infected Af293 to nikkomycin Z (NikZ), a drug inhibiting chitin s...
Source: Viruses - January 10, 2023 Category: Virology Authors: Gabriele Sass Ioly Kotta-Loizou Marife Martinez David J. Larwood David A. Stevens Tags: Article Source Type: research
Molecules, Vol. 28, Pages 435: Immune Defences: A View from the Side of the Essential Oils
Mandras
The use of essential oils is increasingly being investigated among new therapeutic approaches based on medicinal plants and their extracts. With the wide use of synthetic and semi-synthetic antimicrobial drugs, the spread of drug-resistant clinical isolates has increased, and research is directed towards natural products, such as essential oils, as useful antimicrobial resources. In the context of a prospective infection, we compared the impact of essential oils and common antimicrobial agents on the microbicidal activity of human phagocytes. Here, we present the results of our decades-long investigation into t...
Source: Molecules - January 3, 2023 Category: Chemistry Authors: Vivian Tullio Janira Roana Lorenza Cavallo Narcisa Mandras Tags: Review Source Type: research
Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: The American Journal of Tropical Medicine and Hygiene - December 26, 2022 Category: Tropical Medicine Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research
Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: Am J Trop Med Hyg - December 26, 2022 Category: Infectious Diseases Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research
Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: The American Journal of Tropical Medicine and Hygiene - December 26, 2022 Category: Tropical Medicine Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research
Microbiology Profile of COVID-19-Associated Rhino-Orbital Mucormycosis Pathogens in South India
This study describes the microbiological and histopathological features of patients with COVID-19-associated rhino-orbital mucormycosis (ROM) seen at the L V Prasad Eye Institute between May and August 2021. Diagnosed clinically and radiologically, 24 patients with ROM were included in the study. Deep nasal swabs or endoscopically collected nasal swabs or orbital tissues were submitted for microbiological evaluation and in vitro susceptibility testing by microbroth dilution for natamycin, amphotericin B, caspofungin, posaconazole, ketoconazole, and voriconazole. Cultures were processed by 28S ribosomal DNA polymerase chain...
Source: Am J Trop Med Hyg - December 26, 2022 Category: Infectious Diseases Authors: Esther Sheba Savitri Sharma Dilip Kumar Mishra Tarjani Vivek Dave Anasua Ganguly Kapoor Joveeta Joseph Source Type: research
