Medical News Today: Forms of tobacco that give you cancer
Many people try nicotine replacement or vaping as an alternative to smoking cigarettes. However, people often speculate as to whether there is a link between nicotine consumption and cancer. The consensus is also unclear as to whether smokeless tobacco causes cancer. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 31, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Black, Low - Income Women May Not Report Barriers to Care
They are less likely to report barriers to early breast CA detection, less likely to get timely mammogram (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 31, 2018 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Internal Medicine, Nursing, Oncology, Radiology, Journal, Source Type: news

Genetic Risk Score IDs Breast CA Risk in Female Child CA Survivors
Survivors in highest quintile of polygenic risk score have increased relative rate of breast cancer (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 31, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pathology, Journal, Source Type: news

Accuray reports revenue gains in fiscal 1st quarter
Strong sales of its Radixact radiation therapy system helped radiation oncology...Read more on AuntMinnie.comRelated Reading: Accuray brings Radixact to India Accuray highlights CyberKnife prostate studies Accuray posts revenue increases for Q4, fiscal 2018 Accuray wins Indian market clearance for Radixact X9 Accuray lands new deal with Mercy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 31, 2018 Category: Radiology Source Type: news

A Closer Look at HER2-Targeted Therapies
Dr. Adam Brufsky speaks withCancer Network about the evolution and future of HER2-targeted therapy. (Source: CancerNetwork)
Source: CancerNetwork - October 31, 2018 Category: Cancer & Oncology Authors: Adam Brufsky, MD, PhD Source Type: news

First PI3K Inhibitor to Improve Outcomes in HR+/HER2 − Breast Cancer
The SOLAR-1 trial tested whether the PI3K inhibitor alpelisib improved outcomes in HR+, HER2 − breast cancer patients. (Source: CancerNetwork)
Source: CancerNetwork - October 31, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Is Controversy Over NCRT Plus Surgery Warranted in Esophageal Squamous Cell Carcinoma?
A new study adds to evidence examining whether neoadjuvant chemoradiotherapy plus surgery improves survival vs surgery alone in locally advanced ESCC. (Source: CancerNetwork)
Source: CancerNetwork - October 31, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

A Healthy Diet Is Never Too Late With Colon Cancer
WEDNESDAY, Oct. 31, 2018 -- A healthy diet may lower your risk of death from colon cancer, even if you wait until after you're diagnosed with the disease, new research suggests. The study included more than 2,800 colon cancer patients. Those whose... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 31, 2018 Category: General Medicine Source Type: news

Poor Communication May Mean Missing Cancer Poor Communication May Mean Missing Cancer
As a medical student, discovering holes in the system can be frustrating. What happens when a lapse in communication means a missed diagnosis?Medscape Med Students (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Med Students Article Source Type: news

Why You Might Get Kidney Cancer If You Move To Florida
You may want to ask your doctors to think twice before ordering an unnecessary CT scan or treating an incidental “diagnosis.” (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - October 31, 2018 Category: Pharmaceuticals Authors: Peter Ubel, Contributor Source Type: news

Shortage of Histopathologists in the United Kingdom Now Contributing to Record-Long Cancer-Treatment Waiting Times in England
Only 3% of histopathology departments that responded to the Royal College of Pathologists’ workforce census reported enough staff to meet clinical demand There is a chronic shortage of histopathologists in the United Kingdom (UK) and it is being blamed for cancer treatment waiting times that now reach the worst-ever levels, as National Health Service (NHS) […] (Source: Dark Daily)
Source: Dark Daily - October 31, 2018 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Hiring & Human Resources Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing anatomic pathology BBC clinical laboratory Dark Daily dark intelligence group Dark Source Type: news

$2.4M bequest: Children's to name part of new building for executive, wife
Cincinnati Children ’s Hospital plans to name the Bone Marrow Transplant Unit in the Critical Care Building now under construction in honor of the late Mary and Joseph Stern Jr., who recently left $2.4 million to the medical center. Mary Stern died in June at age 97. Joseph Stern, who had been president and chairman of U.S. Shoe Corp. as well as a trustee of Cincinnati Children’s, died in 2010 at age 91. At the time he died, the Hematology and Oncology Research Center at the hospital was named… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 31, 2018 Category: American Health Authors: Barrett J. Brunsman Source Type: news

Here ’s the Healthiest Way to Gain Weight
For most Americans with weight issues, the problem is carrying around too much , not too little. While obesity rates have surged in North America since the 1970s, the proportion of underweight people has remained low—less than 5% of the population, according to a study in The Lancet. These bodyweight trends mean that most health experts are focused on helping people lose weight to avoid disease. But there are also some potentially serious health consequences associated with being clinically underweight, which is usually defined as having a body mass index (BMI) of 18.5 or below. “There are many epidemiologic st...
Source: TIME: Health - October 31, 2018 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Diet/Nutrition Source Type: news

Researchers identify patients facing greatest risk of cancer's return
St. Jude researchers believe gene variations could help identify pediatric cancer survivors who are especially likely to face a breast cancer diagnosis later in life. The findings of a new St. Jude Children’s Research Hospital study determined that childhood cancer survivors with a specific combination of genetic variations are at a much higher risk of breast cancer compared to other survivors of pediatric cancers. Researchers found the combined effect of th e 170 common gene variations is comparable… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 31, 2018 Category: American Health Authors: Caitlin Mullen Source Type: news

Pembro Plus Chemo Now for First-Line Metastatic Squamous NSCLC Pembro Plus Chemo Now for First-Line Metastatic Squamous NSCLC
The FDA has granted approval for immunotherapy with pembrolizumab in combination with chemotherapy to be used first-line in metastatic squamous nonsmall cell lung cancer.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Male Breast Cancer: Current Clinical Practice'Justified'Male Breast Cancer: Current Clinical Practice'Justified '
Despite differences in demographic and disease-related characteristics, male breast cancer patients are treated similarly to female patients, with similar outcomes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

French Study Reveals Potential Mesothelioma Treatment Target
A team of French researchers led by Dr. Christophe Blanquart has identified a substance that may better define the severity of malignant pleural mesothelioma (MPM) in the body and provide clues to more effectively manage the rare cancer. Brain-derived neurotrophic factor, as the name indicates, is a protein found in the brain. BDNF is a growth factor and also appears in other tissues in the body. “It seems that BDNF could be a prognostic marker for MPM patients,” Blanquart told The Mesothelioma Center at Asbestos.com. “The level of BDNF in pleural fluids could reflect the severity of disease.” The...
Source: Asbestos and Mesothelioma News - October 31, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

Prostate cancer: British man now cancer-free after treatment reveals he had no symptoms
A BRITISH man diagnosed with prostate cancer is now cancer-free after having private treatment in Prague. He received a diagnosis despite not experiencing symptoms. (Source: Daily Express - Health)
Source: Daily Express - Health - October 31, 2018 Category: Consumer Health News Source Type: news

A nine-year-old boy who bravely endured years of gruelling treatment is now free of cancer
Henry Hallam, from Plymouth, was diagnosed with neuroblastoma when he was three years old. It affects 100 UK children each year and has one of the lowest survival rates - but he beat it. (Source: the Mail online | Health)
Source: the Mail online | Health - October 31, 2018 Category: Consumer Health News Source Type: news

Genetic Risk Score IDs Breast CA Risk in Female Child CA Survivors
WEDNESDAY, Oct. 31, 2018 -- A polygenic risk score (PRS) can identify subsequent breast cancer risk among childhood survivors of cancer, according to a study published online Oct. 26 in Clinical Cancer Research. Zhaoming Wang, Ph.D., from St. Jude... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 31, 2018 Category: Pharmaceuticals Source Type: news

Black, Low-Income Women May Not Report Barriers to Care
WEDNESDAY, Oct. 31, 2018 -- Black women, women living in poverty, and those with higher levels of distrust are less likely to report barriers to timely screening mammography, according to a study published online Sept. 24 in Cancer. Sage J. Kim,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 31, 2018 Category: Pharmaceuticals Source Type: news

Sex hormone blocker increases likelihood of pregnancy in breast cancer patients
The sex hormone blocker, goserelin, protects the ovaries from breast cancer chemotherapy, improving the likelihood of future pregnancy, according to research published in theJournal of the National Cancer Institute. Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 31, 2018 Category: Endocrinology Source Type: news

Progress in Kidney Cancer Outcomes Through Collaboration, Innovation, and Discovery
In this Special Series, kidney cancer (KC) experts describe how recent advances can be integrated into clinical management strategies and focus on important future priorities, including understanding mechanisms by which KC develops and becomes resistant to standard therapies. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 31, 2018 Category: Consumer Health News Source Type: news

Boosting confidence after breast cancer in Salisbury
This case study illustrates how cancer survivors in Salisbury feel more confident and less fatigued after enhanced support to live better after cancer. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 31, 2018 Category: Consumer Health News Source Type: news

Evaluation of health risk in industrial workers - Oleshchenko AM, Zakharenkov V, Surzhikov DV, Kislitsvna V, Korsakova TG.
The article presents results of evaluating chronic intoxication risks, acute toxic effects risk, carcinogenic risk and risk of occupational diseases due to dust. FINDINGS are that the highest risk levels for chronic intoxication and carciongenic ri... (Source: SafetyLit)
Source: SafetyLit - October 31, 2018 Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news

Takeda raises forecast on cancer drug outlook
(Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - October 31, 2018 Category: Pharmaceuticals Source Type: news

Medical News Today: Does brain size predict brain cancer risk?
New research suggests that having a larger brain may increase the risk of developing aggressive brain cancer. The higher number of brain cells may be why. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 31, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

The Reality of Cancer Biosimilars: Challenges and New Hope
Various challenges still surround the use of cancer biologics, but expert guidance and expiring patents may help expand their use and benefits. (Source: CancerNetwork)
Source: CancerNetwork - October 31, 2018 Category: Cancer & Oncology Authors: Naveed Saleh, MD, MS Source Type: news

Lung Ground-Glass Nodules in Never-Smokers and Smokers Lung Ground-Glass Nodules in Never-Smokers and Smokers
How long should ground glass nodules of the lung be monitored and what are predictors of their growth?Translational Lung Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Dermoscopy of Skin Metastases From Breast Cancer Dermoscopy of Skin Metastases From Breast Cancer
This report highlights the utility of dermoscopy for accurate diagnosis of cutaneous metastatic breast cancer, describing dermoscopic patterns of the disease.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Early Development of De Novo HCC After DAA Therapy Early Development of De Novo HCC After DAA Therapy
The results of this study indicate that chronic HCV patients treated either with PegIFN or an all-oral DAA regimen remain at risk for development of de novo hepatocellular carcinoma.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Comparison of Oxycodone and Morphine for Cancer Pain Comparison of Oxycodone and Morphine for Cancer Pain
Do oxycodone and morphine differ significantly in their analgesic efficacy or tolerability when used as first-line therapy for patients with moderate to severe cancer pain?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Investigators study how a protein factor contributes to cancer cell migration
(University of California - Los Angeles Health Sciences) UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 31, 2018 Category: International Medicine & Public Health Source Type: news

NUS study: RNA defects linked to multiple myeloma progression in high risk patients
(National University of Singapore) Researchers from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore have uncovered an association between RNA abnormalities and MM progression. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 31, 2018 Category: International Medicine & Public Health Source Type: news

Low-fat diet increases cancer survival rate in mice, study finds
(University of California - Los Angeles Health Sciences) Something as simple as a change in diet can potentially help to increase the cancer survival rate of obese children with acute lymphoblastic leukemia, the most common childhood cancer, according to a new study by UCLA scientists. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Is it brain infection or cancer? A new rapid test could hold the answer
(Thomas Jefferson University) A diagnostic test based on cytokine profile could help distinguish between infection and other diseases. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 31, 2018 Category: Infectious Diseases Source Type: news

Minimally invasive surgery for early-stage cervical cancer may increase risk of death
(Massachusetts General Hospital) A study by a multi-institutional research team, including Massachusetts General Hospital physicians, has found evidence that patients receiving minimally invasive radical hysterectomy for early-stage cervical cancer have an increased risk of death compared to patients treated with open surgery. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

For early cervical cancer, open hysterectomy is safer than minimally invasive surgery
(Columbia University Irving Medical Center) A new study found that the risk of death was significantly higher for women with early cervical cancer if they had a minimally invasive hysterectomy instead of open surgery. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Minimally invasive surgery associated with worse survival for women with cervical cancer compared to open hysterectomy
(University of Texas M. D. Anderson Cancer Center) When comparing standard-of-care surgical options for women with early-stage cervical cancer, two studies led by researchers at The University of Texas MD Anderson Cancer Center discovered that minimally invasive radical hysterectomy is associated with higher recurrence rates and worse overall survival (OS), compared to abdominal radical hysterectomy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Minimally invasive surgery leads to worse survival for cervical cancer patients
(Northwestern University) Minimally invasive hysterectomy, a popular procedure for early-stage cervical cancer, turns out to result in worse overall survival for cancer patients than traditional open surgery, reports a new study. More than half of hysterectomies performed for this purpose are minimally invasive. Patients are about 1.65 times more likely to die over four years with the minimally invasive surgery. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Relapsed leukemia flies under immune system's radar
(Washington University School of Medicine) A study from Washington University School of Medicine in St. Louis offers a potential explanation for why many AML patients experience a relapse after a stem cell transplant, and suggests a therapeutic approach that may help to place relapsed patients back into remission. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

University of Arizona researchers make next move in the fight against ovarian cancer
(University of Arizona College of Engineering) Jennifer Barton, engineering professor and director of the University of Arizona's BIO5 Institute, is using an $863,000 grant from the United States Army to test a minimally invasive ovarian cancer screening device in vivo for the first time. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

IU Philanthropic Venture Fund commits $500,000 to drug development company
(Indiana University) The Indiana University Philanthropic Venture Fund has made a commitment to invest $500,000 in NERx Biosciences Inc., a startup company that discovers and develops targeted therapeutics for cancer treatment. IU researcher John J. Turchi founded the company. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 31, 2018 Category: International Medicine & Public Health Source Type: news

UA targeting rhabdomyosarcoma, a rare pediatric cancer with few treatment options
(University of Arizona Health Sciences) UA Cancer Center researcher harnesses 'big data' to identify targeted treatments for rhabdomyosarcoma, a rare cancer that mostly strikes children and teenagers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 31, 2018 Category: International Medicine & Public Health Source Type: news

Cold therapy offers promising prevention against taxane-induced dermatologic events
(George Washington University) Researchers at the George Washington University found skin cooling methods may be the best preventative intervention against taxane-based chemotherapy side effects. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Chirality of vitamin-D derivative affects the protonation states of its receptor protein
(Toyohashi University of Technology) Researchers at Toyohashi University of Technology, in cooperation with researchers at Teijin Pharma Ltd. and Teikyo University, have highlighted the possibility that chirality of vitamin-D derivatives can affect the protonation states of histidine residues in the vitamin-D receptor protein via ab initio molecular simulations and biomedical analyses. This finding emphasizes that protonation states should be considered more precisely in molecular simulations, when investigating specific interactions between candidate drugs and target proteins related to disease pathogenesis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Two-cells-in-one combo therapy could bolster leukemia treatment
(UCLA Samueli School of Engineering) A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

CNIO finds the origin of a type of thrombocytopenia caused by an oncogene
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) This work has allowed to understand, through the study of MASTL protein, the molecular origin of inherited thrombocytopenia in some patients and to successfully explore therapeutic options on a mouse model.MASTL controls the cytoskeleton, the structure that gives cells their shape and governs their mobility and capacity for grouping.Abnormalities in the cytoskeleton of tumor cells facilitate their spreading throughout the body of cancer patients, which is why studying MASTL might have important implications on how to block metastasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Potential markers identified for early detection and prevention of liver cancer
(Frontiers) A new study offers hope of early detection for hepatocellular carcinoma -- the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. The results show a dramatic increase in expression of sugar-burning 'glycolytic' genes in precancerous cirrhotic livers, associated with a significantly higher risk of developing hepatocellular carcinoma. This could lead to a biomarker which identifies those at risk of malignancy, as well as targets for new treatments. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 31, 2018 Category: Biology Source Type: news