Optimizing technologies for discovering cancer cell mutations
(Penn State) Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results. A team of researchers has developed a new framework that can combine three existing methods of finding these large mutations -- or structural variants -- into a single, more complete picture. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 10, 2018 Category: Cancer & Oncology Source Type: news

Social support is critical to life satisfaction in young patients with cancer
(Wiley) Among adolescents and young adults with cancer, social support was the most decisive factor associated with life satisfaction. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings indicate that social support and how young cancer patients process the experience of being ill have far greater importance for their life satisfaction than sociodemographic or medical factors do. September is Childhood Cancer Awareness Month. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 10, 2018 Category: Cancer & Oncology Source Type: news

Maryland Charges Insys With Engaging in Deceptive Opioid Scheme Maryland Charges Insys With Engaging in Deceptive Opioid Scheme
Maryland on Thursday charged Insys Therapeutics Inc with deceptively marketing a powerful opioid pain killer so that it was prescribed inappropriately beyond its intended use with cancer patients.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 10, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Mayo Clinic Radio: Childhood cancer awareness / Ken Burns / Does aspirin prevent heart attack and stroke?
There are four words no parent or family ever wants to hear: Your child has cancer.?Families facing pediatric cancer experience a wide range of emotions, often feeling scared, overwhelmed, frustrated, helpless or hopeless.?And each family member may experience different emotions at different times, making it difficult to navigate and support each other. These and related [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 10, 2018 Category: Databases & Libraries Source Type: news

MSK Cancer Center Orders Staff to ‘ Do a Better Job ’ of Disclosing Industry Ties
In an email to staff members, chief executives at Memorial Sloan Kettering responded to news that a top doctor had failed to report links to companies in research articles. (Source: NYT Health)
Source: NYT Health - September 9, 2018 Category: Consumer Health News Authors: KATIE THOMAS and CHARLES ORNSTEIN Tags: Drugs (Pharmaceuticals) Academic and Scientific Journals Memorial Sloan-Kettering Cancer Center Baselga, Jose Ethics and Official Misconduct Start-ups American Assn for Cancer Research Bristol Myers Squibb Company New England Journal of Me Source Type: news

Cancer time bomb is ready to explode
THOUSANDS of cancer patients could miss out on life-saving treatment as a pioneering drug to help beat the disease will only be available for a limited time. Patients on "game-changing" immunotherapy drugs face having to stop the life-saving treatment because of rules about how long they are allowed to take it. (Source: Daily Express - Health)
Source: Daily Express - Health - September 9, 2018 Category: Consumer Health News Source Type: news

Breast cancer things every woman needs to know... by a breast surgeon who's had it twice
You may have to cope with an altered body image and a treatment-induced menopause, but don ’t let cancer take away your physical connection, says Dr Liz O'Riordan, who was diagnosed in 2015. (Source: the Mail online | Health)
Source: the Mail online | Health - September 9, 2018 Category: Consumer Health News Source Type: news

Two more Peninsula IPOs tell the story of biotech's investment boom
And then there were 15. Two Bay Area biotech companies — one that started its first clinical trial in eye diseases in July, the other a pioneer in the fledgling field of hunting down cancer via a simple blood draw — seek to raise $100 million each in the region’s 14th and 15th life sciences initial public offerings this year. It is the most life sciences IPOs in the Bay Area in a calendar year since 19 were filed in 2014. Guardant Health Inc. of Redwood City and Kodiak Sciences Inc. of Palo… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 9, 2018 Category: American Health Authors: Ron Leuty Source Type: news

Two more Peninsula IPOs tell the story of biotech's investment boom
And then there were 15. Two Bay Area biotech companies — one that started its first clinical trial in eye diseases in July, the other a pioneer in the fledgling field of hunting down cancer via a simple blood draw — seek to raise $100 million each in the region’s 14th and 15th life sciences initial public offerings this year. It is the most life sciences IPOs in the Bay Area in a calendar year since 19 were filed in 2014. Guardant Health Inc. of Redwood City and Kodiak Sciences Inc. of Palo… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 8, 2018 Category: Biotechnology Authors: Ron Leuty Source Type: news

Huang Qi, a foundational herb in Traditional Chinese Medicine (TCM), found to inhibit breast cancer cell proliferation
(Natural News) Huang qi (Astragalus membranaceus) is one of the fundamental herbs in traditional Chinese medicine, with earliest records of its use dating back over 2,000 years ago. Now, a study in BMC Complementary and Alternative Medicine has found that Huang qi is also able to prevent the spread of breast cancer cells in the body. Breast... (Source: NaturalNews.com)
Source: NaturalNews.com - September 8, 2018 Category: Consumer Health News Source Type: news

Top Cancer Researcher Fails to Disclose Corporate Financial Ties in Major Research Journals
A senior official at Memorial Sloan Kettering Cancer Center has received millions of dollars in payments from companies that are involved in medical research. (Source: NYT Health)
Source: NYT Health - September 8, 2018 Category: Consumer Health News Authors: CHARLES ORNSTEIN and KATIE THOMAS Tags: Drugs (Pharmaceuticals) Clinical Trials Conflicts of Interest Memorial Sloan-Kettering Cancer Center New England Journal of Medicine American Society of Clinical Oncology Lancet, The (Journal) Jose Baselga Breast Cancer Ethics and Offici Source Type: news

Bowel cancer symptoms: Having this colour poo could indicate you have the disease
BOWEL cancer symptoms can be subtle and won ’t always necessarily make you ill. However, one way to detect the disease is by looking at the colour of your stools. Here’s what to look out for. (Source: Daily Express - Health)
Source: Daily Express - Health - September 8, 2018 Category: Consumer Health News Source Type: news

A first look at the newly opened Knight Cancer Research Building (Photos)
Five years after Nike co-founder Phil Knight issued a $1 billion challenge to Oregon Health& Science University, the Knight Cancer Research Building opened on Portland ’s South Waterfront. The 320,000-square-foot building will bring together 650 employees, including researchers from different scientific disciplines, under one roof to pursue work in early cancer detection, computational biology, population health, precision medicine and related fields. Most of the funding for the seven-story building,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 8, 2018 Category: Biotechnology Authors: Elizabeth Hayes Source Type: news

Lung cancer patients have the highest malignancy-associated suicide rate in USA: a population-based analysis - Rahouma M, Kamel M, Abouarab A, Eldessouki I, Nasar A, Harrison S, Lee B, Shostak E, Morris J, Stiles B, Altorki NK, Port JL.
PURPOSE: Previous studies have reported that psychological and social distresses associated with a cancer diagnosis have led to an increase in suicides compared to the general population. We sought to explore lung cancer-associated suicide rates in a large... (Source: SafetyLit)
Source: SafetyLit - September 8, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

First US Companies List a CRISPR Trial, for Blood Conditions First US Companies List a CRISPR Trial, for Blood Conditions
Two US companies registered a CRISPR-based treatment for β -thalassemia at ClinicalTrials.gov.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 8, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

A first look at the newly opened Knight Cancer Research Building (Photos)
Five years after Nike co-founder Phil Knight issued a $1 billion challenge to Oregon Health& Science University, the Knight Cancer Research Building opened on Portland ’s South Waterfront. The 320,000-square-foot building will bring together 650 employees, including researchers from different scientific disciplines, under one roof to pursue work in early cancer detection, computational biology, population health, precision medicine and related fields. Most of the funding for the seven-story building,… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 8, 2018 Category: Pharmaceuticals Authors: Elizabeth Hayes Source Type: news

Changes in the architecture around cancer cells can fuel their spread
FINDINGSUCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption. The study shows that acute changes in a single component of the extracellular matrix can trigger a very rapid change in the metabolism and migration of the cell.  BACKGROUNDGiven its importance in the growth and migration in cancer cells, scientists have intensely studied how glucose metabolism can be regulated in response to a variety of both internal and external cues. But little research has focuse...
Source: UCLA Newsroom: Health Sciences - September 8, 2018 Category: Universities & Medical Training Source Type: news

Science Saturday: Quest to unmask an elusive immune cancer
A researcher and her team to journey in search of a worthy goal: better care for patients with lymphoma. When she began practicing medicine, Dr. Lisa Rimsza, a Mayo Clinic hematopathologist, faced a frustration common in the cancer field. After diagnosing patients with an immune system cancer called lymphoma, she couldn?t provide the information they [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 8, 2018 Category: Databases & Libraries Source Type: news

' A Ticking Time Bomb for Heart Disease': What We Heard This Week
(MedPage Today) -- Quotable quotes from MedPage Today's sources (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - September 7, 2018 Category: Hematology Source Type: news

Top scientists claim transfusions of young blood will put an END to sickness in old age
Publishing data in the journal Nature, Dame Linda Partridge, a UCL geneticist, says young blood could allow humans to live a life free of cancer, dementia and heart disease. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2018 Category: Consumer Health News Source Type: news

Predicting Tumor Progression in CRC Patients
It may be possible to predict personalized tumor progression in CRC patient's liquid biopsy and mathematical modeling. (Source: CancerNetwork)
Source: CancerNetwork - September 7, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Gene Variant Linked to Risk of Oral Squamous Cell Carcinoma
A study shows significant association between MTHFR C677T polymorphisms and risk of oral squamous cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - September 7, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

Quiz: Understanding Epigenetics and Genomics of Multiple Myeloma
How much do you know about the genomics of multiple myeloma? Take our latest quiz to sharpen your knowledge. (Source: CancerNetwork)
Source: CancerNetwork - September 7, 2018 Category: Cancer & Oncology Source Type: news

Laser Interstitial Thermal Therapy Shows Promise for Glioblastomas
MRI-guided laser interstitial thermal therapy appears to be safe and effective for glioblastomas and may add an average of 2 months to life expectancy. (Source: CancerNetwork)
Source: CancerNetwork - September 7, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Does Sequential vs Concurrent Treatment Change Outcomes in HER2+ Breast Cancer?
Outcomes for patients with HER2-positive breast cancer did not differ when treated with sequential chemotherapy plus trastuzumab compared with a concurrent approach. (Source: CancerNetwork)
Source: CancerNetwork - September 7, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Study Backs Omitting Axillary Surgery in Certain Breast Ca Patients
(MedPage Today) -- But assessing pCR before surgery remains the obstacle (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - September 7, 2018 Category: Hematology Source Type: news

When a Patient Becomes a Friend When a Patient Becomes a Friend
Dr David Kerr discusses his personal experience with patients who become friends.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

When a Patient Turns Into a Friend When a Patient Turns Into a Friend
Dr David Kerr discusses his personal experience with patients who become friends.Medscape Oncology (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 7, 2018 Category: Surgery Tags: Hematology-Oncology Commentary Source Type: news

' I Wonder if I Betrayed Him': When the Patient Is a Colleague'I Wonder if I Betrayed Him': When the Patient Is a Colleague
David Kerr discusses the loss of a colleague and personal friend whom he treated, and how this experience differed--and did not differ--from his other patient care experiences.Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 7, 2018 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

' I Wonder if I Betrayed Him': When the Patient Is a Friend'I Wonder if I Betrayed Him': When the Patient Is a Friend
David Kerr discusses the loss of a colleague and personal friend whom he treated, and how this experience differed--and did not differ--from his other patient care experiences.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Voriconazole May Boost Risk of Squamous Cell Carcinoma in Transplant Patients Voriconazole May Boost Risk of Squamous Cell Carcinoma in Transplant Patients
Recipients of lung transplants (LT) or hematopoietic cell transplants (HCT) who are taking the antifungal voriconazole may be at increased risk of squamous cell carcinoma (SCC), researchers report.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - September 7, 2018 Category: Transplant Surgery Tags: Hematology-Oncology News Source Type: news

End-Stage Lung Cancer Patients Still Taking Preventive Meds
(MedPage Today) -- Few taken off unnecessary drugs at last hospital discharge (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - September 7, 2018 Category: American Health Source Type: news

Social Determinants Linked to Provision of Primary Care
Strong link for social complexity with primary care indicators for prevention, chronic dz management (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - September 7, 2018 Category: Psychiatry Tags: Endocrinology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Nursing, Oncology, Pediatrics, Psychiatry, Journal, Source Type: news

Boost for & quot;Made in China & quot; Medicine as Chi-Med Wins Key Approval Boost for & quot;Made in China & quot; Medicine as Chi-Med Wins Key Approval
Hutchison China MediTech has won Chinese approval for a closely watched new cancer drug in a significant boost for"made in China" medicine.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Breast cancer symptoms: Watch out for this sign in your arm or hand
BREAST cancer symptoms are important to recognise as this type of cancer is the most common in the UK. The first symptom for women is usually a lump in the breast, but a sign the disease has progressed can appear in your arm or hand. (Source: Daily Express - Health)
Source: Daily Express - Health - September 7, 2018 Category: Consumer Health News Source Type: news

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight Funding Available: NNLM MAR has funding available for two grants of $19,000. Libraries, community-based organizations, schools, health care providers, and other organizations that provide health programming or services within PA, NY, NJ or DE are eligible to apply. Applications are due October 5, 2018, and award funds must be spent by April 30, 2019. Details. September is National Preparedness Month. Disasters Happen. Prepare Now. Learn How. This week: Make and Practice Your Plan. National Network of Libraries of Medicine N...
Source: NN/LM Middle Atlantic Region Blog - September 7, 2018 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

Boston Scientific & #039;s Aggressive M & amp;A Strategy Continues with Augmenix Deal
Tuck-in acquisitions continue to play a key role in Boston Scientific's strategy this year, as evidenced by the company's latest deal, which also happens to be its largest so far in 2018.  The Marlborough, MA-based company has agreed to pay $500 million upfront and up to $100 million for sales-based milestones to acquire Augmenix. This private company is based in Bedford, MA and has developed a product called SpaceOAR, which intended to reduce common and debilitating side effects for men who undergo prostate cancer radiotherapy. Not only is Augmenix the eighth acquisition Boston Scientific has reported this yea...
Source: MDDI - September 7, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Medical News Today: Is regular screening for prostate cancer really necessary?
A panel of experts from the United Kingdom is asking whether regular screening for prostate cancer actually brings enough benefits to outweigh the risks. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 7, 2018 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Cervical Cancer Screening: Who Might Need Co-testing? Cervical Cancer Screening: Who Might Need Co-testing?
Updated recommendations from the USPSTF address the use of co-testing for cervical cancer.Medscape Internal Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Internal Medicine Commentary Source Type: news

Mobile app launches to better connect cancer patients to appropriate care, clinical trials
US and China-based Driver boasts a network of more than 30 cancer treatment centers, and also offers a separate post-care management service. (Source: mobihealthnews)
Source: mobihealthnews - September 7, 2018 Category: Information Technology Source Type: news

Varian Signs Partnership Agreement with Mediheal to Support Cancer Care in Kenya
PALO ALTO, Calif. and NAIROBI, Kenya, Sept. 7, 2018 -- (Healthcare Sales & Marketing Network) -- Varian (NYSE : VAR ) signed a partnership agreement with Mediheal Group of Hospitals to expand access to radiotherapy in Kenya. This comprehensive partnership... Devices, Oncology Varian Medical Systems, radiotherapy, linear accelerator, TrueBeam, Halcyon (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 7, 2018 Category: Pharmaceuticals Source Type: news

Optim Partners with 21st Century Oncology as the Preferred Vendor for Head and Neck Cancer Endoscopy
The ENTity™ XL Nasopharyngoscope has been selected by the leading health care provider as the preferred choice in technology utilized to diagnose and manage patients with head and neck cancers. STURBRIDGE, Mass., Sept. 7, 2018 -- (Healthcare Sales & Mar... Devices, Oncology Optim LLC, ENTityXL, Nasopharyngoscope, FreedomView, OptiLux (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 7, 2018 Category: Pharmaceuticals Source Type: news

Boston Scientific puts up $600m for Augmenix
Boston Scientific (NYSE:BSX) said yesterday that it put $600 million on the table for Augmenix and its SpaceOar device. The deal for Bedford, Mass.-based Augmenix calls for $500 million in up-front cash and another $100 million pegged to sales-based milestones, Boston said. The SpaceOar hydrogel device, which won CE Mark approval in the European Union in 2010 and 510(k) clearance from the FDA in April 2015 , is designed to separate the prostate from the rectal wall during radiation treatment for prostate cancer. The product is delivered through a small needle as a liquid, which then solidifies into a so...
Source: Mass Device - September 7, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Mergers & Acquisitions Urology Wall Street Beat Augmenix Inc. Boston Scientific Source Type: news

Tampa Bay bankers, CFO selected to national list of influential finance executives
The Bank of Tampa's Bill West, Pilot Bank's Rita Lowman and Moffitt Cancer Center's Yvette Tremonti have been selected to a national list of notable financial executives. The Business Journals’ Influencers: Finance spotlights 100 executives who are having an impact on business being done in communities across the nation.  These 100 executives represent both large, nationally known lenders as well as smaller, community based institutions. The group also includes entrepreneurial investors and… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 7, 2018 Category: American Health Authors: Mark Mensheha Source Type: news

Africa:Nigerians Risk Cancer, Others As Counterfeit Phones Flood Market
[Guardian] The use and sale of counterfeit and substandard mobile phones in the country telecommunications space have been increasing to the extent that it has become a menace. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 7, 2018 Category: African Health Source Type: news

Access to CT lung screening varies by population density
Smokers in densely populated regions in the U.S. live significantly closer...Read more on AuntMinnie.comRelated Reading: CT screening program targets nuclear weapons workers Lung cancer overdiagnosis varies widely on CT screening CT lung screening may benefit racial minorities most More CT screening may be needed for high-risk smokers 4 reasons why people seek CT lung cancer screening (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 7, 2018 Category: Radiology Source Type: news

Hypothalamic-Pituitary, Growth Disorders in Cancer Survivors Hypothalamic-Pituitary, Growth Disorders in Cancer Survivors
The Endocrine Society has developed clinical practice guidelines to provide recommendations regarding the treatment of hypothalamic-pituitary and growth disorders in childhood cancer survivors.Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Updates in Pharmacotherapy for Melanoma Updates in Pharmacotherapy for Melanoma
This article reviews the latest new and emerging systemic therapies for advanced melanoma, including immunotherapy and targeted therapy.U.S. Pharmacist (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Bioadhesive, wirelessly powered implant emitting light to kill cancer cells
(Waseda University) A new wirelessly powered light-emitting device, which sticks onto animal tissue like a sticker with tissue-adhesive and elastic nanosheets, could possibly facilitate treatment for hard-to-detect microtumors and deeply located lesions that are hard to reach with standard phototherapy. If clinically applied, the device could be beneficial for cancer patients who seek minimally invasive treatment, helping them live longer and improve their quality of life. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 7, 2018 Category: Cancer & Oncology Source Type: news