Male hormones regulate stomach inflammation in mice
NIEHS research shows that male sex hormones are anti-inflammatory and could lead to new treatment strategies for stomach cancer. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - June 2, 2021 Category: Environmental Health Source Type: news

New class of cancer-fighting compounds discovered by NIEHS-funded team
Oregon State University researchers say the compounds effectively kill liver and breast cancer cells. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - June 2, 2021 Category: Environmental Health Source Type: news

U.S. Supreme Court Rejects J & J Appeal of $2 Billion Talc Verdict
The U.S. Supreme Court rejected a request June 1 from Johnson & Johnson to consider overturning a $2.1 billion award to 22 women who blamed the company’s asbestos-contaminated talcum powder products for causing ovarian cancer. With the Supreme Court declining to consider it, a Missouri state court ruling from 2018 that originally awarded $4.69 billion remains in place. A Missouri court of appeals reduced the award in 2020 to $2.1 billion, but also rejected a J&J effort to dismiss the jury verdict. The appeal did not involve the question of whether the products caused cancer. Johnson & Johnson wanted...
Source: Asbestos and Mesothelioma News - June 2, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news

What Is Life Expectancy of Stage 4 Prostate Cancer
What Is the Life Expectancy of Someone with Stage 4 Prostate Cancer? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 2, 2021 Category: General Medicine Source Type: news

Can a Routine Cancer Scan Flag Depression?
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 2, 2021 Category: General Medicine Source Type: news

Oncology imaging errors are the most common cause of lawsuits
Oncologic imaging represents 44% of radiology malpractice cases with diagnosti...Read more on AuntMinnie.comRelated Reading: Could AI lower malpractice risk for physicians? Pa. man wins $11M award for MRI brain damage U.S. physicians use imaging as defensive medicine Misinterpreted CT scans leading cause of malpractice 4 steps for physicians to influence AI legal issues (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 2, 2021 Category: Radiology Source Type: news

Hormone Therapy, Mammographic Density and Breast Cancer Risk Hormone Therapy, Mammographic Density and Breast Cancer Risk
What have we learned about the joint effect of menopausal hormone therapy and mammographic density on the risk for breast cancer?Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 2, 2021 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Stereotactic Radiotherapy for Early Stage NSCLC Stereotactic Radiotherapy for Early Stage NSCLC
A new review explores the current role of stereotactic body radiation therapy in the treatment of early stage non-small cell lung cancer and highlights recent research.Translational Lung Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 2, 2021 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Huntsman Cancer Institute researchers yield new insights into origins of synovial sarcoma
(Huntsman Cancer Institute) A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads. The study was led by Kevin B. Jones, MD and Bradley R. Cairns, PhD from Huntsman Cancer Institute. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Immunotherapy after surgery reduces deadly relapse risk in advanced bladder cancer
(The Mount Sinai Hospital / Mount Sinai School of Medicine) A phase 3 clinical trial co-led by Mount Sinai researchers is the first to show that immunotherapy after surgery to remove bladder cancer can reduce the risk of relapse for patients who are at high risk of their cancer returning in a deadly metastatic form, according to results published in The New England Journal of Medicine. The immunotherapy nivolumab was used as an adjuvant therapy, which is given after surgery in the hopes of maximizing its effectiveness. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Machine learning brings an early diagnostic for pancreatic cancer a step closer to reality
(London School of Hygiene& Tropical Medicine) Individuals at higher risk of developing pancreatic cancer could be identified earlier using machine learning (ML) techniques which would result in a greater number of patients surviving the disease, suggests a new study published in PLOS ONE. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

La Jolla Institute for Immunology launches new global cancer immunology resource
(La Jolla Institute for Immunology) The National Cancer Institute (NCI) of the National Institutes of Health has granted over $4.2 million to launch the Cancer Epitope Database and Analysis Resource (CEDAR), led by La Jolla Institute for Immunology (LJI) Professors Alessandro Sette, Dr. Biol. Sci., and Bjoern Peters, Ph.D. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2021 Category: International Medicine & Public Health Source Type: news

How is the genome like an open book? New research shows cells' 'library system'
(New York University) The organization of the human genome relies on physics of different states of matter - such as liquid and solid. The findings reveal how the physical nature of the genome changes as cells transform to serve specific functions and point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2021 Category: International Medicine & Public Health Source Type: news

Cancer-promoting Ras protein exists in a pair within cells
(Ruhr-University Bochum) Researchers from Bochum and Osnabr ü ck have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer. With the help of fluorescence markings, they have demonstrated that the protein is deposited in a pair at the cell membrane, and with the very structure that they predicted in theory back in 2012. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Protein disguise could be new target for cancer immunotherapy
(The Francis Crick Institute) Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

NIH supports mathematical optimization of tumor treatment
(Rice University) A Rice University engineer's mathematical model to reduce the side effects suffered by patients undergoing treatment for head and neck cancers now has the support of the National Institutes of Health. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Oncotarget: E6-specific inhibitors as therapeutics for HPV+ head and neck carcinomas
(Impact Journals LLC) " Head and neck squamous cell carcinomas (HNSCC) are heterogeneous tumors that arise in the upper respiratory tract and are the 6th most common cancer worldwide by incidence. " (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Oncotarget: Lung squamous cell carcinoma tumors reveal therapeutic alterations
(Impact Journals LLC) " Lung cancer is the leading cause of cancer-related deaths across the globe with more than 1.7 million deaths annually. " (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Research suggests BMI may not be best obesity indicator to assess risk for lung cancer
(International Association for the Study of Lung Cancer) - New research published in the Journal of Thoracic Oncology (JTO) suggests the method used to calculate how obesity is measured may affect whether it is considered a risk factor for lung cancer. The JTO is an official journal of the International Association for the Study of Lung Cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Replicating patients' tumors to test different treatments
(Universit é de Gen è ve) In order to offer a personalised treatment that best suits the case being treated, scientists led by UNIGE had already developed a spheroidal reproduction of tumours that integrates the tumour cells, but also their microenvironment. Today, the Geneva team has succeeded in integrating two types of immune cells that come directly from the patient into the spheroidal structure, making it possible to test the various possible treatments and select the most effective. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Regulation of the genome affects its 3D structure
(Institute for Research in Biomedicine (IRB Barcelona)) The Molecular Modelling lab at IRB Barcelona describes the impact of DNA methylation, a known gene regulation mechanism, on the 3D structure of the genome and on gene expression.Published in Nature Communications, the work highlights the connections between epigenetic changes, chromatin structure and gene regulation and may have implications for the study of cancer and ageing, among others. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Clinical trial launched following discovery that psychiatric drug may prevent bowel cancer
(Worldwide Cancer Research) The study, published in the journal Nature, shows how a drug available on the NHS can boost fitness of healthy stem cells in the gut, making them more resistant to sabotage from mutant stem cells that cause cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Researchers identify how to prevent cancer metastases
(University of Basel) Metastases can develop in the body even years after apparently successful cancer treatment. They originate from cancer cells that migrated from the original tumor to other organs, and which can lie there inactive for a considerable time. Researchers have now discovered how these " sleeping cells " are kept dormant and how they wake up and form fatal metastases. They have reported their findings in the journal Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Coloring tumors reveals their bad influence
(IMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences) Red2Onco, an innovative genetic mouse model, allows to detect the very initial steps that lead to cancer development. Red2Onco's multi-colour labelling system allows to trace intestinal tumour development after the first oncogenic hit at the single cell level. The research carried out at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences - and the University of Cambridge is now published in the journal Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2021 Category: Cancer & Oncology Source Type: news

Novel Drug Approved by FDA for Some Bile Duct Cancers Novel Drug Approved by FDA for Some Bile Duct Cancers
Infigratinib was approved for use in adults with previously treated unresectable bile duct cancer harboring an FGFR2 fusion or other rearrangement.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 2, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

National Cancer Survivors Day ® 2021 Brings Together Cancer...
On Sunday, June 6, 2021 – National Cancer Survivors Day® – cancer survivors and supporters around the world will unite to recognize cancer survivors, raise awareness of the ongoing challenges...(PRWeb June 02, 2021)Read the full story at https://www.prweb.com/releases/national_cancer_survivors_day_2021_brings_together_cancer_survivors_local_communities_to_raise_awareness_of_survivorship_issues/prweb17973604.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 2, 2021 Category: Pharmaceuticals Source Type: news

ASCO: Incidence of Cervical Cancer Has Decreased in the United States
TUESDAY, June 1, 2021 -- The incidence of cervical cancer has decreased, while the incidence of other human papillomavirus (HPV)-related cancers has increased in the United States, according to a study scheduled to be presented at the annual meeting... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 1, 2021 Category: Pharmaceuticals Source Type: news

Mayo Clinic Top Doc Ousted Over Sexual Relations With Mentees Mayo Clinic Top Doc Ousted Over Sexual Relations With Mentees
High-profile oncologist Axel Grothey, MD, resigned from the Mayo Clinic 3 years ago; only now are details of inappropriate sexual relations with mentees coming to light.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 1, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Inside a Big Pharma cancer drug approval with roots in a small Bay Area biotech
Before CAR-T therapies became one of the hottest areas of cancer drug development, Kristen Hege and her team looked at cell therapies to tackle HIV and solid tumors. More than 20 years later, Hege, now with drug giant Bristol-Myers Squibb Co., is diving into solid tumors again. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 1, 2021 Category: Biotechnology Authors: Ron Leuty Source Type: news

Inside a Big Pharma cancer drug approval with roots in a small Bay Area biotech
Before CAR-T therapies became one of the hottest areas of cancer drug development, Kristen Hege and her team looked at cell therapies to tackle HIV and solid tumors. More than 20 years later, Hege, now with drug giant Bristol-Myers Squibb Co., is diving into solid tumors again. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 1, 2021 Category: American Health Authors: Ron Leuty Source Type: news

Portland startup Gabbi is fighting delayed diagnosis in women's health
The company is building a product to help women better understand their risks of breast cancer and then create action plans that can be taken to health care providers. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - June 1, 2021 Category: Health Management Authors: Malia Spencer Source Type: news

4 Ways Exercise Helps Fight Aging
Everyone knows that exercise is good for you. But it’s not just beneficial for the young, healthy and already fit. It’s also one of the best defenses against the toughest aspects of aging. Exercise not only improves heart and lung health, but research shows that even modest physical activity is good for the brain, bones, muscles and mood. Numerous studies have found that lifelong exercise may keep people healthier for longer; delay the onset of 40 chronic conditions or diseases; stave off cognitive decline; reduce the risk of falls; alleviate depression, stress and anxiety; and may even help people live longer....
Source: TIME: Health - June 1, 2021 Category: Consumer Health News Authors: Liz Seegert Tags: Uncategorized Source Type: news

Optic nerve firing may spark growth of vision-threatening childhood tumor
NIH-funded pre-clinical study supports key role of neural activity in brain cancers. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - June 1, 2021 Category: American Health Source Type: news

U.S. Supreme Court refuses to hear Johnson & Johnson appeal of $2B St. Louis baby powder verdict
Johnson& Johnson's had asked the high court to review a $2.1 billion award won by a group of women who said the company's baby powder caused their ovarian cancer. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - June 1, 2021 Category: Health Management Authors: Greg Edwards Source Type: news

Justices Reject Johnson & Johnson Appeal of $2B Talc Verdict Justices Reject Johnson & Johnson Appeal of $2B Talc Verdict
The Supreme Court is leaving in place a $2 billion verdict in favor of women who claim they developed ovarian cancer from using Johnson& Johnson talc products.Associated Press (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 1, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

New Hearing on Crash That Killed Florida Oncologist New Hearing on Crash That Killed Florida Oncologist
The driver responsible for an automobile accident that killed Florida oncologist Charles Canaan Williams may now be found not guilty by reason of insanity.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 1, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

False-Positive Lymph Nodes on PET Scans After COVID Vaccination False-Positive Lymph Nodes on PET Scans After COVID Vaccination
Cases of false-positive lymph nodes on PET scans, sometimes leading to unnecessary biopsies, are being reported after COVID-19 vaccination.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

FDA ’s Oncology Center of Excellence Launches National Black Family Cancer Awareness Week
Throughout the week, the agency ’s social media platforms will serve as the hub for this historic initiative as participants at health care centers, non-profit associations, and community organizations nationwide raise awareness about the impact of cancer on Black families. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 1, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

J&J to pay $2.1bn in talc cancer case after Supreme Court rejection
Highest court in US refuses to hear appeal despite support from business lobby groups (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - June 1, 2021 Category: Pharmaceuticals Source Type: news

Cancer screening may still be valuable for older individuals
who are outsid...Read more on AuntMinnie.comRelated Reading: COVID-19 widens disparities in breast screening Does digital mammography fall short for surveillance imaging? AI, radiomics can predict cancer in lesions found on breast MRI Women with genetic disorder more reassured after breast screening AI has opportunities for more acceptance in screening mammography (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 1, 2021 Category: Radiology Source Type: news

Kineta Closes $10 Million Financing Round to Advance Anti-VISTA Immuno-oncology Program
SEATTLE, June 1, 2021 -- (Healthcare Sales & Marketing Network) -- Kineta, Inc., a clinical stage biotechnology company focused on the development of novel immunotherapies in oncology, announced today the close of its $10 million financing round. Kineta i... Biopharmaceuticals, Oncology, Venture Capital, Personnel Kineta, anti-VISTA antibody (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 1, 2021 Category: Pharmaceuticals Source Type: news

Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Teclistamab for the Treatment of Relapsed or Refractory Multiple Myeloma
U.S. Milestone Follows European Medicines Agency PRIME Designation for this BCMA Bispecific Antibody for the Treatment of Relapsed or Refractory Multiple Myeloma RARITAN, N.J., June 1, 2021 -- (Healthcare Sales & Marketing Network) -- The Janssen Pharm... Biopharmaceuticals, Oncology, FDA Janssen Pharmaceutical, Johnson & Johnson, teclistamab, Multiple Myeloma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 1, 2021 Category: Pharmaceuticals Source Type: news

Justices reject Johnson & Johnson appeal of $2B talc verdict
The Supreme Court is leaving in place a $2 billion verdict in favor of women who say they developed ovarian cancer from using Johnson & Johnson talc products (Source: ABC News: Health)
Source: ABC News: Health - June 1, 2021 Category: Consumer Health News Tags: Health Source Type: news

Cancer in Kids May Present as Musculoskeletal Symptoms, Complicating Diagnosis Cancer in Kids May Present as Musculoskeletal Symptoms, Complicating Diagnosis
Childhood cancer may present with musculoskeletal symptoms that mimic the features of rheumatic diseases, potentially leading to misdiagnosis, diagnostic delay and inappropriate treatment, caution researchers in Italy.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

' Encouraging' Data on Ipilimumab Plus Anti-PD-1 in Metastatic Melanoma'Encouraging' Data on Ipilimumab Plus Anti-PD-1 in Metastatic Melanoma
For patients with advanced melanoma resistant to anti-PD-L1 monotherapy, combining the CTLA-4 inhibitor ipilimumab with an anti-PD-1 agent'should be favored'over ipilimumab alone as second-line immunotherapy, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

ASCO: Oncologists Underestimate Patient Use of Complementary Medicine
TUESDAY, June 1, 2021 – Oncologists may substantially underestimate how many breast cancer patients are using complementary medicine, according to the results of a survey scheduled to be presented at the annual meeting of the American Society of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 1, 2021 Category: Pharmaceuticals Source Type: news

Patients With Cancer Who Develop Ketoacidosis Fare Badly Patients With Cancer Who Develop Ketoacidosis Fare Badly
Patients with cancer hospitalized for DKA were older and more often had type 2 diabetes, plus a higher likelihood of dying, than those with DKA without cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Teclistamab for the Treatment of Relapsed or Refractory Multiple Myeloma
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for teclistamab in the treatment of relapsed or refractory multiple myeloma. This distinction for teclistamab, an off-the-shelf, T-cell redirecting, bispecific antibody targeting both B-cell maturation antigen (BCMA) and CD3 receptors, follows a PRIME (PRIority MEdicines) designation from the European Medicines Agency (EMA) received earlier this year. Today’s BTD marks the 11th received by Janssen’s ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

100th Elekta Unity MR-Linac goes to St George's Hospital in New Zealand
CHRISTCHURCH, New Zealand, June 1, 2021 -- (Healthcare Sales & Marketing Network) -- Elekta (EKTA-B.ST) announces that St George's Hospital in Christchurch, New Zealand, has ordered an Elekta Unity MR-Linac, making it the 100th device sold since introduct... Devices, Oncology Elekta, Unity MR-Linac, MR-guided, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 1, 2021 Category: Pharmaceuticals Source Type: news