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Biowulf Seminar Series: How to build a dog in 2,392,715,236 simple steps
Biowulf Seminar Series The Biowulf seminar series continues with talks by Biowulf users. The first such seminar features Heidi Parker, the Senior Staff Scientist for the Dog Genome Project at NHGRI The NHGRI Dog Genome Project at NIH and focuses on the genetics of health and body structure in the domestic dog. We are particularly interested in the variation represented in individual dog breeds, which allows us to focus on locating genes involved in both canine cancer and the morphologic traits. Our research yields not only an understanding of how genes interact to create the modern dog breeds we see today and how we can ke...
Source: Videocast - All Events - February 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI Post-Treatment Surveillance Workshop - March 2018 (Day 2)
To discuss issues in post treatment surveillance given the current advances in imaging and in vitro diagnostics. Specific discussions will occur in Breast, Colon, NSCLS, Colorectal Cancer and Testicular cancer. Identify and prioritize histologies and tools that are most suitable to be evaluated in this setting, in NCTN and NCORP clinical trials.Air date: 3/27/2018 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI Post-Treatment Surveillance Workshop - March 2018 (Day 1)
To discuss issues in post treatment surveillance given the current advances in imaging and in vitro diagnostics. Specific discussions will occur in Breast, Colon, NSCLS, Colorectal Cancer and Testicular cancer. Identify and prioritize histologies and tools that are most suitable to be evaluated in this setting, in NCTN and NCORP clinical trials.Air date: 3/26/2018 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mechanistic basis of cancer immunotherapy
NIH Director's Wednesday Afternoon Lecture Series My group ’ s long interest in understanding the cellular mechanisms of the immune response has increasingly focused on the problem of cancer immunology and immunotherapy. We have now established an entire department devoted to this effort, and postdocs in my group seek to understand how checkpoint inhibitors (eg anti-PD-L1), vaccines, immune agonists and their combinations work to produce durable anti-cancer responses.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 4/18/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Of bones, brain, and fat: macrophages and the control of homeostasis
NIH Director's Wednesday Afternoon Lecture Series Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in development, homeostasis and diverse types of cancer and can either restrain or promote cancer progression and metastasis. The Geissmann lab is now building on previous work to investigate mechanisms by which tissue macrophages may control tissue growth and metabolism and whether these same mechanisms play a role in cancer initiation and development.For more information go tohttps://o...
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Harry P. Erba, MD, PhD - A Master-Class on Building Better Therapy for AML: Making the Most of an Increasing Number of Innovative Options
A Master-Class on Building Better Therapy for AML: Making the Most of an Increasing Number of Innovative Options (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - February 9, 2018 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

HPV VLPs: Nature ’ s Nanoparticles for Prevention and Treatment of Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. John Schiller graduated from the University of Wisconsin-Madison with a B.S. in molecular biology in 1975. In 1982, he received a Ph.D. from the Department of Microbiology of the University of Washington in Seattle, then joined the NCI Laboratory of Cellular Oncology as a National Research Service Award postdoctoral fellow in 1983. Dr. Schiller became a senior staff fellow in the Laboratory of Cellular Oncology in 1986 and a senior investigator in 1992. He became chief of the Neoplastic Disease Section of the lab in 1998, deputy lab chief in 2000 and designate...
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Mitochondria control of physiology and disease: beyond ATP
NIH Director ’ s Wednesday Afternoon Lecture Series For decades, the mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles generating metabolites for the production of macromolecules and ATP, respectively. Our work has elucidated that mitochondria have a third distinct role whereby they release reactive oxygen species (ROS) and metabolites such as L-2-hydroxyglutarate to initiate physiological and pathological processes including hypoxic activation of HIFs, cellular differentiation, T cell activation and cancer cell proliferation. Thus, mitochondria function as signaling organelles.For m...
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Hematopoietic stem cells in stress, disease, and aging
NIH Director ’ s Wednesday Afternoon Lecture Series Dr. Passagu é 's research investigates the biology of blood-forming hematopoietic stem cells in normal and deregulated contexts such as development of hematological malignancies and physiological aging.For more information go tohttps://oir.nih.gov/wals/2017-2018Air date: 2/21/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

A comprehensive repertoire of mutational signatures in human cancer
DNA Repair Interest Group videoconferenceAir date: 6/19/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Proteogenomics of Breast Cancer
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Matthew Ellis ’ s clinical and basic research focuses on breast cancer. He has developed neoadjuvant endocrine therapy as an alternative to chemotherapy for promoting breast-conserving therapy in postmenopausal women with ER+ HER2- stage 2 and 3 disease. He developed and validated the Ki67 proliferation marker-based Preoperative Endocrine Prognostic Index which is now undergoing a large validation study (the ALTERNATE study). These clinical studies have provided the clinical context and tumor specimens for seminal investigations into the ER+ breast cancer somati...
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

National Cancer Advisory Board (NCAB) Virtual Meeting - February 2018
The 8th Virtual Meeting of the National Cancer Advisory Board (NCAB)Air date: 2/13/2018 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 25, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Preclinical cancer-target validation: How not to be wrong
Wednesday Afternoon Lecture Series Published and unpublished studies by investigators in the pharmaceutical industry indicate that a disturbingly high number of academic laboratories' reports nominating potential new cancer-drug targets are either non-reproducible or, if reproducible, are not sufficiently robust to form the basis for drug-discovery efforts. The reasons are likely multifactorial, including the ubiquitous use of " down " assays in cancer biology (e.g. decreased cell proliferation, decreased tumor growth, etc.) that incorporate chemical and genetic perturbants that are prone to cause off-target effe...
Source: Videocast - All Events - January 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Single cell analysis of the effector T cell transcriptome
Immunonology IG Seminar Dr. Thomas Ciucci is a post-doctoral fellow in Dr. R é my Bosselut ’ s group within the Laboratory of Immune Cell Biology (LICB). He received a Ph.D. in Genetics and Immunology from the University of Nice, France in 2012. His doctoral research work investigated the relationship between inflammatory immune cells, the tumor environment and bone tissue. Dr. Ciucci joined Dr. Bosselut ’ s group in 2013 to pursue his interests in the regulation of T cell responses. His research has focused on two aspects of T cell differentiation during the immune response. The first, identified a prev...
Source: Videocast - All Events - January 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Translating Cancer Genomics to Clinical Care
NCI's Center for Cancer Research (CCR) Eminent Lectures This monthly lecture series has been established to bring in prominent speakers to stimulate discussion of cutting-edge research areas and facilitate exchange of ideas, possibly leading to fruitful collaborations.Air date: 1/22/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Genetic Compensation and Transcriptional Adaptation
NCI's Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 1/19/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI's Center for Cancer Research (CCR) Grand Rounds
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 2/9/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

CC Grand Rounds: 1) Precision Medicine with DNA-targeted Therapies and the Emerging Role of SLFN11 and 2) Targeting DNA Repair in Small Cell Lung Cancer
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 1/31/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Identifying and Overcoming Mechanisms of Resistance to Immune Attack
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 1/26/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

The Dynamic Interplay between Aging and Cancer
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 1/5/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Autotherapies: Enhancing Our Innate Healing Capacity
Autotherapies are treatments based on the body ’ s natural ability to heal and protect itself. For example, immunotherapy harnesses the body ’ s immune cells to fight cancer and is now in clinical use. In the dental, oral, and craniofacial region, autotherapies could be used to selectively signal the body to repair and regenerate tissue, trigger immune responses, and restore a natural microbial balance. These strategies might also help to heal damaged or diseased tissues in other parts of the body, prevent or treat infections, fight cancer, treat autoimmune conditions, and enhance overall health. Advancing the ...
Source: Videocast - All Events - December 18, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

David L. Rimm, MD, PhD - The Present and the Future of Cancer Immunotherapy Biomarkers: Challenges, Opportunities, and Implications for Pathologists
The Present and the Future of Cancer Immunotherapy Biomarkers: Challenges, Opportunities, and Implications for Pathologists (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - December 13, 2017 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

T Cell-Based Immunotherapy Approaches for Gliomas
NCI's Center for Cancer Research (CCR) Grand Rounds As a physician – scientist, Dr. Okada has been dedicated to brain tumor immunology and development of effective immunotherapy for brain tumor patients for over 20 years. His team was one of very first to discover cytotoxic T lymphocyte (CTL) epitopes in glioma-associated and glioma-specific antigens. Dr. Okada also found critical roles for the integrin receptor very late activation antigen (VLA)-4 and the chemokine CXCL10 in facilitating entry of CTLs to the brain tumor site. Dr. Okada has translated these discoveries into a number of innovative immunotherapy clinic...
Source: Videocast - All Events - December 11, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Personalized vs. Precision? Let ’ s Call It Medicine
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Howard McLeod is Medical Director of the DeBartolo Family Personalized Medicine Institute at the Moffitt Cancer Center. He is Chair of the Department of Individualized Cancer Management and a State of Florida Endowed Chair in Cancer Research. He is also a senior member of the Division of Population Sciences and Professor at the University of South Florida. Dr. McLeod is Chair of the NHGRI eMERGE network external scientific panel and a recent member of the FDA Advisory Committee for Pharmaceutical Science and Clinical Pharmacology and the NIH Human Genome Advisory Coun...
Source: Videocast - All Events - December 4, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Scientists fight cancer’s resistance by re-programming chromatin
Scientists have developed an effective new strategy for treating cancer, which has wiped out the disease to near completion in cellular cultures in the laboratory. The treatment works by controlling chromatin, a group of macromolecules -- including DNA, RNA and proteins -- that houses genetic ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - November 29, 2017 Category: Science Source Type: video

Robert L. Ferris, MD, PhD - Understanding the Impact of Immunotherapy on Head and Neck Cancer: A Look at the Science, Practice, and Future of Multimodal Treatment
Understanding the Impact of Immunotherapy on Head and Neck Cancer: A Look at the Science, Practice, and Future of Multimodal Treatment (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - November 27, 2017 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Extension of Hydroxyl Radical-Based Footprinting Coupled with Mass Spectrometry for In Cell and In Vivo Protein Analysis
Proteomics Interest Group In recent years, protein footprinting coupled with mass spectrometry has been used to identify protein-protein interaction sites and regions of conformational change through modification of solvent accessible sites in proteins. Hydroxyl radical-based footprinting (HRBF) approaches utilize hydroxyl radicals to oxidatively modify the side chains of solvent accessible amino acids. There are several approaches to generate radicals for oxidation including synchrotron radiation and electrochemistry. One HRBF method, fast photochemical oxidation of proteins (FPOP), utilizes an excimer laser for photolysi...
Source: Videocast - All Events - November 27, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Monocyte Heterogeneity: Implications for Cancer
Immunonology IG Seminar Monocytes are key cells that drive the rapid innate immune response. We discovered that a subset of monocytes, nonclassical monocytes (CD14dim in humans and Ly6C- in mice), function in the vasculature to recognize metastasizing tumor cells. Once these cells recognize tumor cells, they orchestrate the killing of these cells to prevent metastasis. This presentation will discuss how nonclassical monocytes regulate tumor cell killing, and will discuss the possible use of nonclassical monocytes in cancer immunotherapy.Air date: 11/29/2017 4:15:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 20, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Transcriptional Regulation of Neuroinflammation
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Lazarevic received her B.Sc. Microbiology degree from the University of Nottingham (UK) and Ph.D. degree in Molecular Virology and Microbiology from the University of Pittsburgh. Following her post-doctoral training in the laboratory of Dr. Laurie Glimcher at Harvard School of Public Health, Dr. Lazarevic was recruited as a tenure-track investigator in the Experimental Immunology Branch, CCR. Her laboratory is interested in how transcription factors regulate differentiation and effector function of CD4+ T helper (Th) cells in the context of autoimmune disorders with e...
Source: Videocast - All Events - November 13, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

2018 Demystifying Medicine: The New Frontier: Immunotherapy of cancer
The Demystifying Medicine Lecture Series is designed to help bridge the gap between advances in biology and their applications to major human diseases. The lectures include presentations of patients, pathology, diagnosis, and therapy in the context of major diseases and current research. All clinicians, trainees including fellows, medical students, Ph.D. students, and other healthcare and research professionals are welcome to attend.For more information go tohttps://demystifyingmedicine.od.nih.gov/Air date: 2/6/2018 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 2, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board - November 2017
The 10th Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory BoardAir date: 11/29/2017 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - November 2, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

TRACO 2017: Lymphoma and Genomics
Translational Research in Clinical Oncology (TRACO) Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in developing and implementing many new technologies, such as nanotechnology, next generation seq...
Source: Videocast - All Events - November 1, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Cells as Anti-Cancer Drugs: Entering Mainstream Oncology
12th annual Philip S. Chen, Jr., Ph.D. Distinguished Lecture on Innovation and Technology Transfer The Office of Intramural Research, Office of the Director, NIH, invites you to the 12th annual Philip S. Chen, Jr., Ph.D. Distinguished Lecture on Innovation and Technology Transfer. Dr. Steven A. Rosenberg will present “ Cells as Anti-Cancer Drugs: Entering Mainstream Oncology. ” Dr. Rosenberg is Branch Chief and Senior Investigator at the Surgery Branch, National Cancer Institute.For more information go tohttps://www.ott.nih.gov/twelfth-annual-philip-s-chen-jr-phd-distinguished-lecture-innovation-and-technology-...
Source: Videocast - All Events - October 27, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Stem Cell Aging
GeroScience Interest Group The Trans-NIH GeroScience Interest Group (GSIG), cordially invites you to its fall seminar, featuring Dr. Sean Morrison. Dr. Morrison is the Director of the Children ’ s Medical Center Research Institute at UT Southwestern and is the Mary McDermott Cook Chair in Pediatric Genetics as well as an Investigator of the Howard Hughes Medical Institute. The Morrison laboratory studies the cellular and molecular mechanisms that regulate the function of stem cells and cancer cells in the nervous and hematopoietic systems. The laboratory is particularly interested in the mechanisms that regulate stem...
Source: Videocast - All Events - October 26, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

The two faces of the IL-15- Janus Kinase-Stat system: implications for the immunotherapy of autoimmune diseases and cancer
NIH Director's Wednesday Afternoon Lecture Series Dr. Walmann will present the annual William Paul lecture. Dr. Waldmann defined the IL-2 receptor alpha and beta subunits using the daclizumab antibody he discovered, an antibody that is approved by the FDA. He co-discovered IL-15 and performed the first in-human clinical trial with this agent in patients with malignancy. Furthermore, Waldmann defined molecular abnormalities of the common gamma cytokine, Jak/Stat signaling pathway in HTLV-1 associated adult T-cell lymphoma and translated this discovery with a trial of a Jak inhibitor in patients with this disorder.For more i...
Source: Videocast - All Events - October 26, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Principles of Epigenetics and Chromatin in Development and Human Disease
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Ali Shilatifard, Professor and Chairman of the Department of Biochemistry and Molecular Genetics of the Northwestern University Feinberg School of Medicine, is a world renown biochemist and molecular biologist. He is a respected expert in the field of transcription and epigenetics, specifically as it relates to cancer biology. He has an immense interest in understanding the intricate molecular mechanisms of the regulation of gene expression, the mechanisms that activate or suppress a particular gene ’ s traits. As a Jane Coffin Childs postdoctoral fellow...
Source: Videocast - All Events - October 23, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Aneuploidy and Cancer - A Complicated Relationship
NCI's Center for Cancer Research (CCR) Eminent Lecture Dr. Amon received her B.S. and Ph.D. from the University of Vienna. She completed a two-year post-doctoral fellowship with Ruth Lehmann at the Whitehead Institute and was subsequently named a Whitehead Fellow for three years. In 1999, she joined the MIT Koch Institute for Integrative Cancer Research and the Department of Biology where she holds the Kathleen and Curtis Marble Chair for Cancer Research. Dr. Amon ’ s honors include the 2003 Alan T. Waterman Award, the 2007 Paul Marks Prize, the 2008 National Academy of Sciences Molecular Biology Award, and the 2013 ...
Source: Videocast - All Events - October 18, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Developing Therapies for Ras-Driven Tumors
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Cichowski ’ s research goals are to elucidate mechanisms that drive human cancer, identify novel therapeutic targets, and generate robust animal models to facilitate these efforts. A related goal is to establish collaborative relationships with clinicians to translate basic scientific findings into clinical trials. Her principal scientific interest is to understand how the Ras pathway, which is deregulated in the majority of human cancers, promotes tumorigenesis. She and her colleagues have been investigating this question in nervous system tumors, prostate, lun...
Source: Videocast - All Events - October 16, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Computing cures: discovery through the lens of a computational microscope
NIH Director's Wednesday Afternoon Lecture Series Dr. Amaro ’ s scientific interests lie at the intersection of computer-aided drug discovery and biophysical simulation methods. She has a long-standing interest in incorporating structural and dynamical information derived from all-atom molecular dynamics simulations in drug discovery programs, and has worked in a variety of disease areas, including infectious diseases and cancer. Her lab ’ s work on p53 revealed a novel druggable pocket that clarified the mechanism of action for a compound in clinical trials. This work served as the basis for the formation of a...
Source: Videocast - All Events - October 13, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Prevention of Progression in Multiple Myeloma
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Irene Ghobrial is an Associate Professor at Dana-Farber Cancer Institute (DFCI), Harvard Medical School, Boston, MA and an Associate member of the Broad Institute, Cambridge, MA. She is the director of the Michele& Stephen Kirsch Laboratory and co-director of the Center for Prevention of Progression of Blood Cancers (CPOP) at DFCI. In addition, she is the co-leader of the Blood Cancer Research Partnership (BCRP), a consortium for innovative clinical trials of community oncology sites coordinated by DFCI. Dr. Ghobrial received her medical degree from Cairo Universi...
Source: Videocast - All Events - October 2, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Innate Immunity in Neurodegeneration
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Marco Colonna received his medical degree with honors from the School of Medicine at Parma University in 1983, and completed his specialization in Internal Medicine at Parma University in 1988. He began his postdoctoral training as a Research Fellow at the Istituto Nazionale per la Ricerca sul Cancro in Genova, Italy, followed by work as a Research Affiliate in the Department of Molecular Immunology at Roswell Park Memorial Institute in Buffalo, New York and as a Research Fellow in Pathology at Dana Farber Cancer Institute and Harvard Medical School. He then became a ...
Source: Videocast - All Events - September 25, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

The development and Function of Regulatory T cells
Immunology Interest Group Seminar Series Dr. Chen ’ s research focuses on elucidating mechanisms of T-cell immunity and tolerance and manipulating T-cell immunity versus tolerance in animal models to understand the pathogenesis of and develop immunotherapy for autoimmunity, cancer and infectious diseases. Among his many scientific contributions to biomedical research, Dr. Chen is the first to discover that TGF-beta induces Foxp3 gene in naive CD4+ T cells and converts them into regulatory T cells (iTregs, pTregs). The paper describing this finding has been cited for more than 4000 times. He has also demonstrated that...
Source: Videocast - All Events - September 25, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Guy Young, MD - Assessing Recent Advances in Hemophilia A Management: What Are the Key Learnings From Berlin?
Assessing Recent Advances in Hemophilia A Management: What Are the Key Learnings From Berlin? (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - September 18, 2017 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

NIH Research Festival Plenary Session III - " The Cancer Moonshot "
The Cancer Moonshot was launched in 2016 with the stated goal of achieving in five years what would otherwise take a decade of cancer research. To identify those areas of cancer research that were poised for acceleration, a Blue Ribbon Panel was convened with representatives from across the cancer continuum. The panel developed a series of recommendations designed to accelerate our understanding of cancer. This session will review those recommendations, describe the extramural programs that are being established, and highlight three of the intramural programs that are being launched as part of the Cancer Moonshot.For more ...
Source: Videocast - All Events - September 12, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

How Telomeres Solve the End-Protection Problem
NCI Center for Cancer Research Eminent Lecture Series Dr. de Lange's lab studies telomeres, protective elements at the ends of chromosomes critical for the stability and maintenance of the genetic information. Deficiency in telomere function can cause genomic alterations found in cancer, and the gradual loss of telomeres contributes to aging of human cells. Dr. de Lange seeks to understand how telomere protection is established and what happens when telomere function is lost during the early stages of tumor formation. Dr. de Lange ’ s group is working to determine the mechanism by which each shelterin protein inhibi...
Source: Videocast - All Events - September 11, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

A nanolaser known as the spaser can serve as a biocompatible probe capable of finding cancer cells
A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the blood stream and then killing these cells, according to a new research study. The study found the spaser can be used as an optical probe and when ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - September 7, 2017 Category: Science Source Type: video

Novel Personalized Care Directions for Gliomas
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Arnab Chakravarti is Chair and Professor of Radiation Oncology at the Arthur G. James Hospital, Richard J. Solove Research Institute, Ohio State University Comprehensive Cancer Center, where he also holds the Klotz Family Chair of Cancer Research and serves as the Director of the Brain Tumor Program. Nationally, he is Chair of the Board of Directors of the International Society of Neuro-Radiation Biology, Board of Directors of the Ohio Neuro-Oncology Consortium, Chair of the Radiation Therapy and Oncology Group (RTOG) Brain Tumor Translational Research Subcomm...
Source: Videocast - All Events - September 5, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI's Center for Cancer Research (CCR) Eminent Lectures
This monthly lecture series has been established to bring in prominent speakers to stimulate discussion of cutting-edge research areas and facilitate exchange of ideas, possibly leading to fruitful collaborations.Air date: 3/19/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 1, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI's Center for Cancer Research (CCR) Grand Rounds
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 3/16/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 1, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

NCI's Center for Cancer Research (CCR) Grand Rounds
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 3/9/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 1, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video