Midatech Pharma Commences First In-Human Study Of Brain Cancer Drug
(Source: Clinical Trials And Noteworthy Treatments For Brain Tumors)
Source: Clinical Trials And Noteworthy Treatments For Brain Tumors - May 25, 2018 Category: Cancer & Oncology Source Type: clinical trials

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant
Conditions:   Minimal Residual Disease;   Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Myeloid Leukemia Interventions:   Biological: Daratumumab;   Procedure: Donor Lymphocyte Infusion;   Other: Laboratory Biomarker Analysis Sponsors:   Sumithira Vasu;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Effect of Group Led Creative Writing on Mood in Cancer Patients
Condition:   Cancer Patients Interventions:   Other: Creative Writing Workshop;   Other: Independent Writing - Control Group Sponsor:   Milton S. Hershey Medical Center Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Oral AMXT 1501 Dicaprate in Combination With DFMO
Conditions:   Cancer;   Solid Tumor;   Solid Carcinoma;   Advanced Cancer Interventions:   Drug: AMXT1501;   Drug: DFMO Sponsor:   Aminex Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Urinary TF and Endo180 in Early Pancreatic Cancer Detection
Conditions:   Cancer of Pancreas;   Pancreas Cyst Intervention:   Sponsors:   Hull and East Yorkshire Hospitals NHS Trust;   University of Hull Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Condition:   Breast Cancer Intervention:   Radiation: IORT Sponsor:   Mount Carmel Health System Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Hybrid APC Therapy in Early Central Lung Cancer
Condition:   Lung Cancer Intervention:   Procedure: Hybrid APC Sponsor:   Jiayuan Sun Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Novel Imaging in Staging of Primary Prostate Cancer
Condition:   High Risk Prostate Cancer Interventions:   Diagnostic Test: Whole body contrast enhanced computer tomography;   Diagnostic Test: 99mTC-HMDP planar bone scintigraphy (BS);   Diagnostic Test: 99mTc-HMDP single photon emission computer tomography/computer tomography;   Diagnostic Test: Whole-body magnetic resonance imaging;   Diagnostic Test: Fluorine-18-prostate specific membrane antigen-1007- positron emission tomography/computer tomography Sponsors:   Turku University Hospital;   University of Turku Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

FID-007 in Treating Participants With Advanced Solid Tumors
Conditions:   Advanced Malignant Solid Neoplasm;   Refractory Malignant Solid Neoplasm Interventions:   Other: Laboratory Biomarker Analysis;   Drug: PEOX-based Polymer Encapsulated Paclitaxel FID-007;   Other: Pharmacokinetic Study Sponsors:   University of Southern California;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
Condition:   Hematologic Malignancies Intervention:   Drug: APG-2575 Sponsor:   Ascentage Pharma Group Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Intervention for Sleep Disturbance in HCT Survivors
Conditions:   Sleep Disturbance;   Sleep Disorder Interventions:   Other: mHealth Stepped-care Intervention;   Other: Educational Control Condition;   Other: Questionnaire;   Other: Interview;   Other: Qualitative Interviews Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   American Cancer Society, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
Conditions:   Cervical Cancer;   Microsatellite Instability (MSI)-High Endometrial Cancer;   Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]);   Esophageal Cancer;   Hepatocellular Carcinoma;   Melanoma (Uveal Melanoma Excluded);   Merkel Cell Carcinoma;   Mesothelioma;   MSI-high Colorectal Cancer;   Non-small Cell Lung Cancer (NSCLC);   Ovarian Cancer;   Squamous Cell Carcinoma of the Head and Neck (SCCHN);   Small Cell Lung Cancer (SCLC); &n...
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant
Conditions:   Minimal Residual Disease;   Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Myeloid Leukemia Interventions:   Biological: Daratumumab;   Procedure: Donor Lymphocyte Infusion;   Other: Laboratory Biomarker Analysis Sponsors:   Sumithira Vasu;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

FID-007 in Treating Participants With Advanced Solid Tumors
Conditions:   Advanced Malignant Solid Neoplasm;   Refractory Malignant Solid Neoplasm Interventions:   Other: Laboratory Biomarker Analysis;   Drug: PEOX-based Polymer Encapsulated Paclitaxel FID-007;   Other: Pharmacokinetic Study Sponsors:   University of Southern California;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Intervention for Sleep Disturbance in HCT Survivors
Conditions:   Sleep Disturbance;   Sleep Disorder Interventions:   Other: mHealth Stepped-care Intervention;   Other: Educational Control Condition;   Other: Questionnaire;   Other: Interview;   Other: Qualitative Interviews Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   American Cancer Society, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
Conditions:   Cervical Cancer;   Microsatellite Instability (MSI)-High Endometrial Cancer;   Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]);   Esophageal Cancer;   Hepatocellular Carcinoma;   Melanoma (Uveal Melanoma Excluded);   Merkel Cell Carcinoma;   Mesothelioma;   MSI-high Colorectal Cancer;   Non-small Cell Lung Cancer (NSCLC);   Ovarian Cancer;   Squamous Cell Carcinoma of the Head and Neck (SCCHN);   Small Cell Lung Cancer (SCLC); &n...
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
Condition:   Hematologic Malignancies Intervention:   Drug: APG-2575 Sponsor:   Ascentage Pharma Group Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Novel Imaging in Staging of Primary Prostate Cancer
Condition:   High Risk Prostate Cancer Interventions:   Diagnostic Test: Whole body contrast enhanced computer tomography;   Diagnostic Test: 99mTC-HMDP planar bone scintigraphy (BS);   Diagnostic Test: 99mTc-HMDP single photon emission computer tomography/computer tomography;   Diagnostic Test: Whole-body magnetic resonance imaging;   Diagnostic Test: Fluorine-18-prostate specific membrane antigen-1007- positron emission tomography/computer tomography Sponsors:   Turku University Hospital;   University of Turku Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Hybrid APC Therapy in Early Central Lung Cancer
Condition:   Lung Cancer Intervention:   Procedure: Hybrid APC Sponsor:   Jiayuan Sun Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Condition:   Breast Cancer Intervention:   Radiation: IORT Sponsor:   Mount Carmel Health System Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Urinary TF and Endo180 in Early Pancreatic Cancer Detection
Conditions:   Cancer of Pancreas;   Pancreas Cyst Intervention:   Sponsors:   Hull and East Yorkshire Hospitals NHS Trust;   University of Hull Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Oral AMXT 1501 Dicaprate in Combination With DFMO
Conditions:   Cancer;   Solid Tumor;   Solid Carcinoma;   Advanced Cancer Interventions:   Drug: AMXT1501;   Drug: DFMO Sponsor:   Aminex Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Effect of Group Led Creative Writing on Mood in Cancer Patients
Condition:   Cancer Patients Interventions:   Other: Creative Writing Workshop;   Other: Independent Writing - Control Group Sponsor:   Milton S. Hershey Medical Center Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Midatech Pharma Commences First In-Human Study Of Brain Cancer Drug
(Source: Clinical Trials And Noteworthy Treatments For Brain Tumors)
Source: Clinical Trials And Noteworthy Treatments For Brain Tumors - May 25, 2018 Category: Cancer & Oncology Source Type: clinical trials

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant
Conditions:   Minimal Residual Disease;   Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes;   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Myeloid Leukemia Interventions:   Biological: Daratumumab;   Procedure: Donor Lymphocyte Infusion;   Other: Laboratory Biomarker Analysis Sponsors:   Sumithira Vasu;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Effect of Group Led Creative Writing on Mood in Cancer Patients
Condition:   Cancer Patients Interventions:   Other: Creative Writing Workshop;   Other: Independent Writing - Control Group Sponsor:   Milton S. Hershey Medical Center Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Oral AMXT 1501 Dicaprate in Combination With DFMO
Conditions:   Cancer;   Solid Tumor;   Solid Carcinoma;   Advanced Cancer Interventions:   Drug: AMXT1501;   Drug: DFMO Sponsor:   Aminex Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Urinary TF and Endo180 in Early Pancreatic Cancer Detection
Conditions:   Cancer of Pancreas;   Pancreas Cyst Intervention:   Sponsors:   Hull and East Yorkshire Hospitals NHS Trust;   University of Hull Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Condition:   Breast Cancer Intervention:   Radiation: IORT Sponsor:   Mount Carmel Health System Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Hybrid APC Therapy in Early Central Lung Cancer
Condition:   Lung Cancer Intervention:   Procedure: Hybrid APC Sponsor:   Jiayuan Sun Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Novel Imaging in Staging of Primary Prostate Cancer
Condition:   High Risk Prostate Cancer Interventions:   Diagnostic Test: Whole body contrast enhanced computer tomography;   Diagnostic Test: 99mTC-HMDP planar bone scintigraphy (BS);   Diagnostic Test: 99mTc-HMDP single photon emission computer tomography/computer tomography;   Diagnostic Test: Whole-body magnetic resonance imaging;   Diagnostic Test: Fluorine-18-prostate specific membrane antigen-1007- positron emission tomography/computer tomography Sponsors:   Turku University Hospital;   University of Turku Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

FID-007 in Treating Participants With Advanced Solid Tumors
Conditions:   Advanced Malignant Solid Neoplasm;   Refractory Malignant Solid Neoplasm Interventions:   Other: Laboratory Biomarker Analysis;   Drug: PEOX-based Polymer Encapsulated Paclitaxel FID-007;   Other: Pharmacokinetic Study Sponsors:   University of Southern California;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
Condition:   Hematologic Malignancies Intervention:   Drug: APG-2575 Sponsor:   Ascentage Pharma Group Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Intervention for Sleep Disturbance in HCT Survivors
Conditions:   Sleep Disturbance;   Sleep Disorder Interventions:   Other: mHealth Stepped-care Intervention;   Other: Educational Control Condition;   Other: Questionnaire;   Other: Interview;   Other: Qualitative Interviews Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   American Cancer Society, Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
Conditions:   Cervical Cancer;   Microsatellite Instability (MSI)-High Endometrial Cancer;   Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]);   Esophageal Cancer;   Hepatocellular Carcinoma;   Melanoma (Uveal Melanoma Excluded);   Merkel Cell Carcinoma;   Mesothelioma;   MSI-high Colorectal Cancer;   Non-small Cell Lung Cancer (NSCLC);   Ovarian Cancer;   Squamous Cell Carcinoma of the Head and Neck (SCCHN);   Small Cell Lung Cancer (SCLC); &n...
Source: ClinicalTrials.gov - May 25, 2018 Category: Research Source Type: clinical trials

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma
Condition:   Glioblastoma Interventions:   Drug: Ibrutinib;   Radiation: Radiation;   Drug: Temozolomide (TMZ) Sponsor:   Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

PSMA PET Registry (18F-DCFPyL)
Condition:   Carcinoma of Prostate Intervention:   Diagnostic Test: 18F-DCFPyL Sponsor:   University Health Network, Toronto Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

High-dose Intensity Modulatd Radiotherapy and Concurrent Chemotherapy in Esophageal Cancer
Condition:   Esophageal Cancer Interventions:   Radiation: standard chemoradiotherapy;   Radiation: experimental chemoradiotherapy Sponsor:   Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

The American Society of Hematology (ASH) Research Registry: A Multicenter Research Registry of Patients With Hematologic Disease
Condition:   Benign and Malignant Hematologic Diseases Intervention:   Combination Product: Protease Inhibitors Sponsor:   American Society of Hematology Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Immunotherapy Based on Tumor Associated Antigen-specific Immune Effector Cells
Condition:   Cancer Intervention:   Biological: Engineered Immune Cells Sponsor:   Shenzhen Geno-Immune Medical Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Phase II Study of Concurrent Sorafenib and Intensity-modulated Radiotherapy (IMRT) for Advanced Hepatocellular Carcinoma
Condition:   Hepatocellular Carcinoma, Radiotherapy, Sorafenib Intervention:   Radiation: concurrent sorafenib and IMRT, followed sorafenib maintenance Sponsor:   Chinese Academy of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC
Conditions:   NSCLC;   Non-small Cell Lung Cancer Intervention:   Drug: Osimertinib Sponsor:   Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients
Conditions:   Pulmonary Fibrosis;   Lung Cancer Interventions:   Drug: [68Ga]CBP8;   Diagnostic Test: PET Imaging Sponsors:   Massachusetts General Hospital;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Muscadine Plus (MPX) In Men With Prostate Cancer
Condition:   Adenocarcinoma of the Prostate Interventions:   Drug: Muscadine Plus;   Drug: Placebos Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Ketogenic Diet and Chemotherapy in Affecting Recurrence in Patients With Stage IV Breast Cancer
Condition:   Stage IV Breast Cancer AJCC v6 and v7 Interventions:   Dietary Supplement: Dietary Intervention;   Other: Laboratory Biomarker Analysis;   Drug: Paclitaxel;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration Sponsor:   Ohio State University Comprehensive Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer
Conditions:   Adenocarcinoma;   Pancreatic Neoplasms;   Neoplasm, Glandular;   Neoplasms;   Neoplasms Pancreatic;   Digestive System Neoplasm;   Endocrine Gland Neoplasms;   Digestive System Disease;   Pancreatic Diseases;   Endocrine System Diseases Interventions:   Drug: Nab-paclitaxel;   Drug: Gemcitabine;   Drug: Capecitabine;   Drug: Cisplatin;   Drug: Irinotecan Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Not yet recruiting (Sour...
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

A Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib
Condition:   ALK-positive Advanced NSCLC Intervention:   Drug: Brigatinib Sponsor:   Ariad Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

An Analysis of Treatment Timelines for Lung Cancer Patients Across System Evolutions
Condition:   Lung Cancer Intervention:   Sponsor:   St Elizabeth Healthcare Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Apatinib Combined With Oral Etoposide in Metastatic HER2 Negative Breast Cancer
Condition:   Breast Cancer Intervention:   Drug: apatinib+oral etoposide Sponsor:   Chinese Academy of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials

Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery
Conditions:   Prostate Cancer;   Opioid Use Interventions:   Drug: Opioid Reduction Intervention;   Behavioral: Current Care Sponsor:   Johns Hopkins University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2018 Category: Research Source Type: clinical trials