PSMA Therapy and Immunotherapy in Kidney Cancer
Conditions: Metastatic Renal Cell Carcinoma; Metastatic Clear Cell Renal Cell Carcinoma Interventions: Drug: Pembrolizumab; Drug: 177Lu-PNT2002; Drug: (F-18)-DCFPyL Sponsors: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Merck Sharp& Dohme LLC; Lantheus Medical Imaging Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Probability of OncotypeDx to Reallocate as Low or High Risk of Recurrence Breast Cancer Patients With Uncertain Biology
Conditions: Breast Cancer Sponsors: Fondazione Sandro Pitigliani; Genomic Health ®, Inc.; Istituto Toscano Tumori Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Real-World Use of Nivolumab for the Treatment of Patients With Metastatic Upper Gastrointestinal Cancer in Canada
Conditions: Upper Gastrointestinal Cancer Interventions: Drug: Nivolumab Sponsors: Bristol-Myers Squibb Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Clinical Efficacy of 125I Seed Implantation in the Treatment of Refractory Differentiated Thyroid Cancer
Conditions: Thyroid Neoplasms Interventions: Radiation: Iodine-125 brachytherapy Sponsors: Jiangxi Provincial Cancer Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients?
Conditions: Cancer; Chronic Obstructive Pulmonary Disease; Surgery-Complications Interventions: Device: Active alarms from WARD software Sponsors: Rigshospitalet, Denmark; Bispebjerg Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Pilot Study to Assess the Ability of Stereotactic Radiotherapy to Restore the Efficacy of Immunotherapy in Patients With Metastatic Cancer.
Conditions: Metastatic Cancer Interventions: Radiation: Stereotactic Radiotherapy Sponsors: Elsan Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer
Conditions: Colon Cancer Interventions: Procedure: Laparoscopic right hemicolectomy with transrectal specimen extraction Sponsors: National Cancer Center, China Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Conditions: Oropharyngeal Squamous Cell Carcinoma; Human Papillomavirus Infection Interventions: Genetic: Pre-Radiation Dental Evaluation/Sample Collection; Other: Pre-Study Visit; Genetic: Oral Medicine Consultation Visit/Sample Collection Sponsors: Wake Forest University Health Sciences; InnoTech Precision Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)
Conditions: Extensive Stage-small Cell Lung Cancer Interventions: Drug: Ifinatamab deruxtecan; Drug: Atezolizumab; Drug: Carboplatin; Drug: Etoposide Sponsors: Daiichi Sankyo; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Toripalimab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer
Conditions: Biliary Tract Neoplasms Immunotherapy Interventions: Drug: Toripalimab; Drug: Lenvatinib; Drug: Gemox Chemotherapy (Gemox or GC) Sponsors: Peking Union Medical College Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI
Conditions: To Investigate the Potential Value of CDK4/6 Inhibitor in NSCLC Patients Undergoing Acquired Resistance to Third-generation EGFR TKIs Interventions: Drug: Osimertinib plus Dalpiciclib Sponsors: Tianjin Medical University Cancer Institute and Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast Cancer
Conditions: Breast Cancer Interventions: Radiation: Preoperative accelerated partial breast irradiation; Procedure: Breast conserving surgery; Procedure: Sentinel node procedure; Procedure: Biopsy track removal Sponsors: The Netherlands Cancer Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Comparison of MRI AI-cTB Versus Routine cTB in Prostate Cancer Diagnosis: a Prospective Randomized Controlled Trial
Conditions: Prostate Cancer Interventions: Procedure: MRI-AI guided cognitive prostate targeted biopsy; Procedure: Routine cognitive prostate targeted biopsy Sponsors: Peking University First Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers
Conditions: Cancer of the Prostate; Anxiety Interventions: Behavioral: TEMPO; Other: Active Monitoring dyads ' anxiety Sponsors: St. Mary ' s Research Center, Canada; Princess Margaret Hospital, Canada; University of Calgary; Sunnybrook Health Sciences Centre; University of British Columbia; McGill University; Simon Fraser University; Universit é de Sherbrooke; Memorial University of Newfoundland; Université de Montréal; Centre intégré de santé et de services sociaux (CISSS) de Laval Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy
Conditions: Anaplastic Thyroid Cancer Interventions: Drug: Dabrafenib + Trametinib Sponsors: Saint Petersburg State University, Russia Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials