The Ca < sup > 2+ < /sup > channel TRPV4 is dispensable for Ca < sup > 2+ < /sup > influx and cell volume regulation during hypotonic stress response in human keratinocyte cell lines
Cell Calcium. 2023 Mar 11;111:102715. doi: 10.1016/j.ceca.2023.102715. Online ahead of print.ABSTRACTCell swelling as a result of hypotonic stress is counteracted in mammalian cells by a process called regulatory volume decrease (RVD). We have recently discovered that RVD of human keratinocytes requires the LRRC8 volume-regulated anion channel (VRAC) and that Ca2+ exerts a modulatory function on RVD. However, the ion channel that is responsible for Ca2+ influx remains unknown. We investigated in this study whether the Ca2+-permeable TRPV4 ion channel, which functions as cell volume sensor in many cell types, may be involve...
Source: Cell Calcium - March 18, 2023 Category: Cytology Authors: Dirk Ritzmann Magdalena Jahn Susanne Heck Cristina Jung Tiziana Cesetti Nathalie Couturier R üdiger Rudolf Naemi Reuscher Claudia Buerger Oliver Rauh Torsten Fauth Source Type: research

Decreasing tobacco use promotes ulcer healing in a patient with Buerger's disease
We describe a case of a patient with Buerger's disease who experienced ulcer healing and pain improvement through reduced tobacco use. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 23, 2023 Category: General Medicine Authors: Sandra Jaroonwanichkul, John C. Hall Tags: CASE REPORT Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Atherosclerosis)
Source: Atherosclerosis - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Do Patients With Arterial Occlusive Disease of Different Etiologies Benefit Equally From Cilostazol?
CONCLUSION: Patients with nonatherosclerotic arterial occlusive disease also benefit from cilostazol, but patients with Buerger disease or diabetic angiopathy seem to benefit less. Combining cilostazol with anticoagulant or antiaggregant agents and closer monitoring of these patients may produce better results.PMID:36763036 | DOI:10.14503/THIJ-21-7747 (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - February 10, 2023 Category: Cardiology Authors: Burak Can Depboylu Serkan Yazman Bugra Harmandar Muruvvet Funda Tetik Hande Istar Kadir Arslan Gokhan Ilhan Source Type: research

Psychiatric sequelae of thromboangiitis obliterans: a  case report and review of the literature 
ConclusionThe pathophysiology of psychosis secondary to Buerger ’s is not yet well characterized which adds to the complexity of managing these cases. Recognizing that cerebral manifestations of this disease may evolve several years after the onset of peripheral thromboangiitic features is important for following the natural history and considering measures th at may reduce the burden of illness. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 30, 2023 Category: General Medicine Source Type: research

IJERPH, Vol. 20, Pages 2493: Psychopathology, Protective Factors, and COVID-19 Among Adolescents: A Structural Equation Model
Buerger Since the outbreak of the COVID-19 pandemic in December 2019 and the associated restrictions, mental health in children and adolescents has been increasingly discussed in the media. Negative impacts of the pandemic, including a sharp increase in psychopathology and, consequently, reduced quality of life, appear to have particularly affected children and young people, who may be especially vulnerable to the adverse effects of isolation. Nevertheless, many children and adolescents have managed to cope well with the restrictions, without deterioration of their mental health. The present study therefore explored th...
Source: International Journal of Environmental Research and Public Health - January 30, 2023 Category: Environmental Health Authors: Christin Scheiner Christian Seis Nikolaus Kleindienst Arne Buerger Tags: Article Source Type: research

Linking early-life bilingualism and cognitive advantage in older adulthood
Neurobiol Aging. 2022 Dec 14;124:18-28. doi: 10.1016/j.neurobiolaging.2022.12.005. Online ahead of print.ABSTRACTPrevious studies have identified bilingualism as a protective factor against dementia. Here we aimed to test whether being bilingual at different life stages impacts cognition and brain structure in older adulthood. We included 746 participants from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE). Assessment of bilingualism at 3 life stages (early: 13-30, middle: 30-65 and late: over 65 years old) was determined with the Lifetime of Experiences Questionnaire. Individuals reporting bilingu...
Source: Neurobiology of Aging - January 27, 2023 Category: Geriatrics Authors: Tommaso Ballarini Elizabeth Kuhn Sandra R öske Slawek Altenstein Claudia Bartels Friederike Buchholz Katharina Buerger Peter Dechent Laura Dobisch Michael Ewers Klaus Fliessbach Silka Dawn Freiesleben Ingo Frommann Tatjana Gabelin Wenzel Glanz Doreen G à Source Type: research

Linking early-life bilingualism and cognitive advantage in older adulthood
Neurobiol Aging. 2022 Dec 14;124:18-28. doi: 10.1016/j.neurobiolaging.2022.12.005. Online ahead of print.ABSTRACTPrevious studies have identified bilingualism as a protective factor against dementia. Here we aimed to test whether being bilingual at different life stages impacts cognition and brain structure in older adulthood. We included 746 participants from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE). Assessment of bilingualism at 3 life stages (early: 13-30, middle: 30-65 and late: over 65 years old) was determined with the Lifetime of Experiences Questionnaire. Individuals reporting bilingu...
Source: Neurobiology of Aging - January 27, 2023 Category: Geriatrics Authors: Tommaso Ballarini Elizabeth Kuhn Sandra R öske Slawek Altenstein Claudia Bartels Friederike Buchholz Katharina Buerger Peter Dechent Laura Dobisch Michael Ewers Klaus Fliessbach Silka Dawn Freiesleben Ingo Frommann Tatjana Gabelin Wenzel Glanz Doreen G à Source Type: research

Linking early-life bilingualism and cognitive advantage in older adulthood
Neurobiol Aging. 2022 Dec 14;124:18-28. doi: 10.1016/j.neurobiolaging.2022.12.005. Online ahead of print.ABSTRACTPrevious studies have identified bilingualism as a protective factor against dementia. Here we aimed to test whether being bilingual at different life stages impacts cognition and brain structure in older adulthood. We included 746 participants from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE). Assessment of bilingualism at 3 life stages (early: 13-30, middle: 30-65 and late: over 65 years old) was determined with the Lifetime of Experiences Questionnaire. Individuals reporting bilingu...
Source: Neurobiology of Aging - January 27, 2023 Category: Geriatrics Authors: Tommaso Ballarini Elizabeth Kuhn Sandra R öske Slawek Altenstein Claudia Bartels Friederike Buchholz Katharina Buerger Peter Dechent Laura Dobisch Michael Ewers Klaus Fliessbach Silka Dawn Freiesleben Ingo Frommann Tatjana Gabelin Wenzel Glanz Doreen G à Source Type: research

Linking early-life bilingualism and cognitive advantage in older adulthood
Neurobiol Aging. 2022 Dec 14;124:18-28. doi: 10.1016/j.neurobiolaging.2022.12.005. Online ahead of print.ABSTRACTPrevious studies have identified bilingualism as a protective factor against dementia. Here we aimed to test whether being bilingual at different life stages impacts cognition and brain structure in older adulthood. We included 746 participants from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE). Assessment of bilingualism at 3 life stages (early: 13-30, middle: 30-65 and late: over 65 years old) was determined with the Lifetime of Experiences Questionnaire. Individuals reporting bilingu...
Source: Neurobiology of Aging - January 27, 2023 Category: Geriatrics Authors: Tommaso Ballarini Elizabeth Kuhn Sandra R öske Slawek Altenstein Claudia Bartels Friederike Buchholz Katharina Buerger Peter Dechent Laura Dobisch Michael Ewers Klaus Fliessbach Silka Dawn Freiesleben Ingo Frommann Tatjana Gabelin Wenzel Glanz Doreen G à Source Type: research